End-of-Life Care in Patients with Lung Cancer
Lung cancer is among the most frequently occurring malignancies in the world and an increasing cause of cancer death in both men and women (Centers for Disease Control and Prevention 2002). Fewer than 15% of patients who develop lung cancer survive five years (Fry et al. 1999; Quddus et al. 2001), underscoring the need to address palliative care needs and end-of-life issues with this patient population. The preceding chapter focused on symptom management during lung cancer therapy, while this chapter will address advanced care planning, withdrawal of ventilatory support, issues in palliative care, and the relief of symptoms and suffering during the terminal phase of the disease.
KeywordsLung Cancer Palliative Care Morphine Sulfate Subcutaneous Infusion Effective Palliation
Unable to display preview. Download preview PDF.
- Bardgett D, Howard C, Murray GR, Calvey TN, Williams NE (1984) Plasma concentration and bioavailability of a buccal preparation of morphine sulfate. Br J Clin Pharmacol 17: 198–199Google Scholar
- Davis C (1995) The role of nebulised drugs in palliating respiratory symptoms from malignant disease. Eur J Palliat Care 2: 9–15Google Scholar
- Emanuel LL, Gunten CF von, Ferris FD (1999) The Education for Physicians on End-of-Life Care (EPEC©) Curriculum. American Medical Association, ChicagoGoogle Scholar
- Fainsinger R, Miller MJ, Bruera E, Hanson J, Maceachern T (1991) Symptom control during the last week of life on a palliative care unit. J Palliat Care 7:5–11Google Scholar
- Goodlin SJ (1997) What is palliative care? Hosp Prac 32:13–16Google Scholar
- Miles S (1995) Rapid extubation protocol. University of Minnesota, Minneapolis. Available at http://wings.buffalo.edu/faculty/ research/bioethics/miles. Accessed August 2002Google Scholar
- Pannuti F, Rossi AP, Iafelice G, Marraro D, Camera P, Cricca A, Strocchi E (1982) Control of chronic pain in very advanced cancer patients with morphine hydrochloride administered by oral, rectal, and sublingual routes. Clinical report and preliminary results of morphine pharmacokinetics. Pharmacol Res Commun 14:369–380PubMedCrossRefGoogle Scholar
- Quddus AM, Kerr GR, Price A, Gregor A (2001) Long-term survival in patients with non-small cell lung cancer treated with palliative radiotherapy. Clin Oncol 13:95–98Google Scholar
- Storey P (1998) Symptom control in dying. In Berger A et al. (eds): Principles and Practice of Supportive Oncology. Lippincott Raven Publishers, Philadelphia, pp 741–748Google Scholar
- Taylor JW, Simon KB(1990) Possible intramuscular midazolam-associated cardiorespiratory arrest and death. DICP (Ann Pharmacother) 24:695–697Google Scholar