DNA-Based Fixed Gain Amplifiers and Linear Classifier Circuits

  • David Yu Zhang
  • Georg Seelig
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 6518)


DNA catalysts have been developed as methods of amplifying single-stranded nucleic acid signals. The maximum turnover (gain) of these systems, however, often varies based on strand and complex purities, and has so far not been well-controlled. Here we introduce methods for controlling the asymptotic turnover of strand displacement-based DNA catalysts and show how these could be used to construct linear classifier systems.


Catalytic Reaction Autocatalytic Reaction Catalytic Turnover Threshold Element Negative Gain 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  • David Yu Zhang
    • 1
  • Georg Seelig
    • 2
  1. 1.California Institute of TechnologyPasadenaUSA
  2. 2.University of WashingtonSeattleUSA

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