Abstract
Storage of regular platelet concentrates (PCs) is limited to 5 days, predominantly due to the risk of possible bacterial contamination. Alternative approaches for platelet storage May result in a prolonged storage period. In this study PCs were cryopreserved with a new storage solution (ThromboSol; LifeCell Corp., Branchburg, USA) [1,2]. CD62p expression is a useful Measure for quality control during platelet storage [3]. To verify platelet activation flow cytometric analyses was performed in the cryopreserved PCs [4]. For this purpose the expression of an activationdependent neoepitope (CD62p) was analyzed on platelet surface in PCs before and after platelet cryopreservation.
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Siemensen, M.K., Brockmann, M.A., Geidel, K., Sputtek, A., Kuehnl, P., Gutensohn, K. (2003). Platelet Activation before and after Cryopreservation of Platelet Concentrates with a new Storage Solution. In: Scharrer, I., Schramm, W. (eds) 32nd Hemophilia Symposium. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-18150-4_47
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DOI: https://doi.org/10.1007/978-3-642-18150-4_47
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-43884-7
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