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Facing the Challenge: A Rational Strategy for Fluid and Volume Management

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Annual Update in Intensive Care and Emergency Medicine 2011

Part of the book series: Annual Update in Intensive Care and Emergency Medicine 2011 ((AUICEM,volume 1))

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Abstract

Perioperative fluid and volume therapy is an important aspect relevant to outcome in the treatment of patients undergoing surgery and on the intensive care unit (ICU). New findings concerning the endothelial surface layer, its physiological functions and its role under pathological conditions, have led not only to a new understanding of the vascular barrier function, but also to challenges to traditional strategies for volume replacement in the operating room (OR) and in the ICU. The various studies comparing restrictive versus liberal fluid management are not directly comparable and are in most instances neither related to the phys?iological basis of perioperative fluid loss, nor do they differ between colloid and crystalloid administration for volume resuscitation.

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References

  1. Chappell D, Jacob M, Hofmann-Kiefer K, Conzen P, Rehm M (2008) A rational approach to perioperativ fluid management. Anesthesiology 109: 723–740

    Article  PubMed  Google Scholar 

  2. Starling E (1896) On the absorption of fluid the connective tissue spaces. J Physiol (Lond) 19: 312–326

    CAS  Google Scholar 

  3. Adamson RH, Lenz JF, Zhang X, et al (2004) Oncotic pressures opposing filtration across non-fenestrated rat microvessels. J Physiol 557: 889–907

    Article  PubMed  CAS  Google Scholar 

  4. Chappell D, Jacob M, Becker BF, et al (2008) Expedition Glykokalyx. Ein neu entdecktes “Great Barrier Reef“. Anaesthesist 57: 959–969

    Article  PubMed  CAS  Google Scholar 

  5. Chappell D, Westphal M, Jacob M (2009) The impact of the glycocalyx on microcirculatory oxygen distribution in critical illness. Curr Opin Anaesthesiol 22: 155–162

    Article  PubMed  Google Scholar 

  6. Rehm M, Haller M, Orth V, et al (2001) Changes in blood volume and hematocrit during acute preoperative volume Loading with 5 % albumin or 6 % hetastarch solutions in patients before radical hysterectomy. Anesthesiology 95: 849–856

    Article  PubMed  CAS  Google Scholar 

  7. Rehm M, Zahler S, Lotsch M, et al (2004) Endothelial glycocalyx as an additional barrier determining extravasation of 6 % hydroxyethyl starch or 5 % albumin solutions in the coronary vascular bed. Anesthesiology 100: 1211–1223

    Article  PubMed  CAS  Google Scholar 

  8. Fahraeus R, Lindqvist T (1931) The viscosity of the blood in narrow capillary tubes. Am J Physiol 96: 562–568

    CAS  Google Scholar 

  9. Desjardins C, Duling BR (1990) Heparinase treatment suggests a role for the endothelial cell glycocalyx in regulation of capillary hematocrit. Am J Physiol 258: H647–H654

    PubMed  CAS  Google Scholar 

  10. Rehm M, Bruegger D, Christ F, et al (2007) Shedding of the endothelial glycocalyx in patients undergoing major vascular surgery with global and regional ischemia. Circulation 116: 1896–1906

    Article  PubMed  CAS  Google Scholar 

  11. Bernfield M, Gotte M, Park PW, et al (1999) Functions of cell surface heparan sulfate proteoglycans. Annu Rev Biochem 68: 729–777

    Article  PubMed  CAS  Google Scholar 

  12. Shih GC, Hajjar KA (1993) Plasminogen and plasminogen activator assembly on the human endothelial cell. Proc Soc Exp Biol Med 202: 258–264

    PubMed  CAS  Google Scholar 

  13. Bruegger D, Jacob M, Rehm M, et al (2005) Atrial natriuretic peptide induces shedding of endothelial glycocalyx in coronary vascular bed of guinea pig hearts. Am J Physiol Heart Circ Physiol 289: H1993–H1999

    Article  PubMed  CAS  Google Scholar 

  14. Nelson A, Berkestedt I, Schmidtchen A, Ljunggren L, Bodelsson M (2008) Increased levels of glycosaminoglycans during septic shock: Relation to mortality and the antibacterial actions of plasma. Shock 30: 623–627

    Article  PubMed  CAS  Google Scholar 

  15. Jacob M, Chappell D, Conzen P, et al (2008) Blood volume is normal after preoperative overnight fasting. Acta Anaesthesiol Scand 52: 522–529

    Article  PubMed  CAS  Google Scholar 

  16. Kamp-Jensen M, Olesen KL, Bach V, et al (1990) Changes in serum electrolyte and atrial natriuretic peptide concentrations, acid-base and hemodynamic status after rapid infusion of isotonic saline and Ringer lactate solution in healthy volunteers. Br J Anaesth 64: 606–610

    Article  PubMed  CAS  Google Scholar 

  17. Lamke LO, Nilsson GE, Reithner HL (1977) Water loss by evaporation from the abdominal cavity during surgery. Acta Chir Scand 413: 279–284

    Google Scholar 

  18. Sear JW (2005) Kidney dysfunction in the postoperative period. Br J Anaesth 95: 20–32

    Article  PubMed  CAS  Google Scholar 

  19. Desborough JP (2000) The stress response to trauma and surgery. Br J Anaesth 85: 109–117

    Article  PubMed  CAS  Google Scholar 

  20. Rehm M, Orth V, Kreimeier U, et al (2001) Changes in blood volume during acute normovolemic hemodilution with 5 % albumin or 6 % hydroxyethylstarch and intraoperative retransfusion. Anaesthesist 50: 569–579

    Article  PubMed  CAS  Google Scholar 

  21. Rehm M, Orth V, Kreimeier U, et al (2000) Changes in intravascular volume during acute normovolemic hemodilution and intraoperative retransfusion in patients with radical hysterectomy. Anesthesiology 92: 657–664

    Article  PubMed  CAS  Google Scholar 

  22. Robarts WM (1979) Nature of the disturbance in the body fluid compartments during and after surgical operations. Br J Surg 66: 691–695

    Article  PubMed  CAS  Google Scholar 

  23. Chan ST, Kapadia CR, Johnson AW, Radcliffe AG, Dudley HA (1983) Extracellular fluid volume expansion and third space sequestration at the site of small bowel anastomoses. Br J Surg 70: 36–39

    Article  PubMed  CAS  Google Scholar 

  24. Lowell JA, Schifferdecker C, Driscoll DF, Benotti PN, Bistrian BR (1990) Postoperative fluid overload: not a benign problem. Crit Care Med 18: 728–733

    Article  PubMed  CAS  Google Scholar 

  25. Shoemaker WC, Appel PL, Kram HR (1988) Tissue oxygen debt as a determinant of lethal and non-lethal postoperative organ failure. Crit Care Med 16: 1117–1120

    Article  PubMed  CAS  Google Scholar 

  26. Holte K, Sharrock NE, Kehlet H (2002) Pathophysiology and clinical implications of perioperative fluid excess. Br J Anaesth 89: 622–632

    Article  PubMed  CAS  Google Scholar 

  27. Gottrup F, Firmin R, Rabkin J, Halliday BJ, Hunt TK, (1987) Directly measured tissue oxygen tension and arterial oxygen tension assess tissue perfusion. Crit Care Med 15: 1030–1036

    Article  PubMed  CAS  Google Scholar 

  28. Marx G, Pedder S, Smith L, et al (2004) Resuscitation from septic shock with capillary leakage: Hydroxyethyl starch (130 kd), but not ringer’s solution maintains plasma volume and systemic oxygenation. Shock 21: 336–341

    Article  PubMed  CAS  Google Scholar 

  29. Verheij J, van Lingen A, Raijimakers PG, et al (2006) Effect of fluid loading with saline or colloids on pulmonary permeability, oedema and lung injury score after cardiac and and major vascular surgery. Br J Anaesth 96: 21–30

    Article  PubMed  CAS  Google Scholar 

  30. Wiedemann HP, Wheeler AP, Bernard GR, et al (2006) Comparison of two fluid-management strategies in acute lung injury. N Engl J Med 354: 2564–2575

    Article  PubMed  CAS  Google Scholar 

  31. Waters JH, Gottlieb A, Schoenwald P, Popovich MJ, Sprung J, Nelson DR (2001) Normal saline versus lactated Ringer’s solution for intraoperative fluid management in patients undergoing abdominal aortic aneurysm repair: an outcome study. Anesth Analg 93: 817–822

    Article  PubMed  CAS  Google Scholar 

  32. Robarts WM (1979) Nature of the disturbance in the body fluid compartments during and after surgical operations. Br J Surg 66: 691–695

    Article  PubMed  CAS  Google Scholar 

  33. Sakr Y, Payen D, Reinhart K, et al (2007) Effects of hydroxyethyl starch administration on renal function in critically ill patients. Br J Anaesth 98: 216–224

    Article  PubMed  CAS  Google Scholar 

  34. Cochrane Injuries Group (1998) Human albumin administration in critically ill patients: systematic review of randomised controlled trials. Cochrane Injuries Group Albumin Reviewers. BMJ 317: 235–240

    Google Scholar 

  35. The SAFE Study Investigators (2004) A comparison of albumin and saline for fluid resuscitation in the intensive care unit. N Engl J Med 350: 2247–2256

    Article  Google Scholar 

  36. Schortgen F, Girou E, Deye N, Brochard L; GRYCO Study Group (2008) The risk associated with hyperoncotic colloids in patients with shock. Intensive Care Med 34: 2157–2168

    Article  PubMed  Google Scholar 

  37. Boldt J, Brosch Ch, Röhm K, Papsdorf M, Mengistu A (2008) Comparison of the effects of gelatin and a modern hydroxyethyl starch solution on renal function and inflammatory response in elderly cardiac surgery patients. Br J Anaesth 100: 457–464

    Article  PubMed  CAS  Google Scholar 

  38. Mahmood A, Gosling P, Vohra RK (2007) Randomized clinical trial comparing the effects on renal function of hydroxyethyl starch or gelatin during aortic aneurysm surgery. Br J Surg 94: 427–433

    Article  PubMed  CAS  Google Scholar 

  39. Boldt J (2009) Modern rapidly degradable hydroxyethyl starches: current concepts. Anesth Analg 108: 1574–1582

    Article  PubMed  Google Scholar 

  40. Boldt J (2007) The balanced concept of fluid resuscitation. Br J Anaesth 99: 312–315

    Article  PubMed  CAS  Google Scholar 

  41. Legendre C, Thervet E, Page B, Percheron A, Noel LH, Kreis H (1993) Hydroxyethylstarch and osmotic-nephrosis-like lesions in kidney transplantation. Lancet 342: 248–249

    Article  PubMed  CAS  Google Scholar 

  42. Cittanova ML, LeBlanc I, Legendre C, Mouquet C, Riou B, Coriat P (1996) Effects of hydroxyethyl starch in brain-dead kidney donors on renal function in kidney-transplant recipients. Lancet 348: 1620–1622

    Article  PubMed  CAS  Google Scholar 

  43. Brunkhorst FM, Engel C, Bloos F, et al (2008) Intensive insulin therapy and pentastarch resuscitation in severe sepsis. N Engl J Med 358: 125–139

    Article  PubMed  CAS  Google Scholar 

  44. Moran M, Kapsner C (1987) Acute renal failure associated with elevated plasma oncotic pressure. N Engl J Med 317: 150–153

    Article  PubMed  CAS  Google Scholar 

  45. Neff TA, Doelberg M, Jungheinrich C (2003) Repetitive large-dose infuson of the novel hydroxyethyl starch 130/0.4 in patients with severe head injury. Anesth Analg 96: 1453–1459

    Article  PubMed  CAS  Google Scholar 

  46. Nohé B, Johannes T, Reutershan J, et al (2005) Synthetic colloids attenuate leukocyte-endothelial interactions by inhibition of integrin function. Anesthesiology 103: 759–767

    Article  PubMed  Google Scholar 

  47. Feng X, Yan W, Wang Z, et al (2007) Hydroxyethyl starch, but not modified fluid gelatin, affects inflammatory response in a rat model of polymicrobial sepsis with capillary leakage. Anesth Analg 104: 624–630

    Article  PubMed  CAS  Google Scholar 

  48. Wang P, Li Y, Li J (2009) Hydroxyethyl starch 130/0,4 prevents the early pulmonary inflammatory response and oxidative stress after hemorrhagic shock and resuscitation in rats. Int Immunopharmacol 9: 347–353

    Article  PubMed  CAS  Google Scholar 

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Heckel, K., Strunden, M.S., Reuter, D.A. (2011). Facing the Challenge: A Rational Strategy for Fluid and Volume Management. In: Vincent, JL. (eds) Annual Update in Intensive Care and Emergency Medicine 2011. Annual Update in Intensive Care and Emergency Medicine 2011, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-18081-1_31

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  • DOI: https://doi.org/10.1007/978-3-642-18081-1_31

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-18080-4

  • Online ISBN: 978-3-642-18081-1

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