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Depression

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Psychoendokrinologie und Psychoimmunologie

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Zusammenfassung

Die Depression stellt weltweit eines der größten Gesundheitsprobleme dar. Bei einer Lebenszeitprävalenz von 17% kann davon ausgegangen werden, dass ungefähr eine von sechs Personen im Verlauf ihres Lebens eine depressive Störung entwickeln wird. Die Depression ist gekennzeichnet durch eine Kombination von Symptomen, zu welchen profunde depressive Verstimmung, Anhedonie (d. h. Verlust von Freude und Interesse an belohnenden Reizen), Irritabilität, Antriebsarmut, Veränderungen von Appetit, Schlaf und Libido, Gefühle von Wertlosigkeit und Schuld, Konzentrationsstörungen und Suizidalität gehören. Die Symptome der Depression führen zu einer markanten Beeinträchtigung der Lebensqualität und des Funktionsniveaus der betroff enen Person. Die Depression ist mit einer erhöhten Mortalität durch Suizid assoziiert. Weiterhin steht die Depression in Zusammenhang mit einem erhöhten Risiko für verschiedene medizinische Erkrankungen, die zu den führenden Gesundheitsproblemen in unserer Gesellschaft gehören, wie z. B. die koronare Herzkrankheit und Diabetes mellitus. Darüber hinaus wird die Prognose von chronischen medizinischen Erkrankungen, wie z. B. Karzinomerkrankungen, durch eine vorliegende Komorbidität mit der Depression deutlich verschlechtert (Krishnan u. Nestler 2008).

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Author information

Authors and Affiliations

  1. Department of Psychiatry and Behavioral Science, Emory University School of Medicine, 101 Woodruff Circle, Suite 4005, 30322, Atlanta, USA

    Christine Heim Ph. D.

  2. Department of Psychiatry and Behavioral Science, Emory University School of Medicine, 1365-B Clift on Rd, 5th floor , 30322, Atlanta, USA

    Prof. Dr. Andrew H. Miller

Authors
  1. Christine Heim Ph. D.
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  2. Prof. Dr. Andrew H. Miller
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Editors and Affiliations

  1. Klinische Psychologie und Psychotherapie, Psychologisches Institut, Universität Zürich, Binzmühlestraße 14/26, 8050, Zürich, Schweiz

    Ulrike Ehlert

  2. Universitätsklinik für Allgemeine Innere Medizin, Kompetenzbereich für Psychosomatische Medizin, Universitätsspital, Inselspital, 3010, Bern, Schweiz

    Roland von Känel

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© 2011 Springer-Verlag Berlin Heidelberg

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Heim, C., Miller, A.H. (2011). Depression. In: Ehlert, U., von Känel, R. (eds) Psychoendokrinologie und Psychoimmunologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-16964-9_19

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  • DOI: https://doi.org/10.1007/978-3-642-16964-9_19

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-16963-2

  • Online ISBN: 978-3-642-16964-9

  • eBook Packages: Medicine (German Language)

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