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Genitourinary

  • María I. Martínez León
  • Juan E. Gutiérrez
  • Luisa Ceres Ruiz
Chapter
Part of the Learning Imaging book series (LEARN)

Abstract

Wilms’ tumor (WT) is the most common intra-abdominal malignancy found in children (0.8 per 100,000 people per year). It originates from the kidney by abnormal proliferation of the metanephric blastema. The histological spectrum of this tumor ranges from elements of the renal blastema to aggressive sarcomatous variants (4–10% of WT). An association has been described between the loss of the WT1 suppressor gene found in chromosome 11 and the development of this tumor, and it may be seen in relation to WAGR syndrome (Wilms’ tumor, Aniridia, Genitourinary anomalies, and mental Retardation). Clinical presentation consists of a flank mass and hematuria, as well as hypertension, fever, and anemia.

Keywords

Renal Tumor Renal Mass Clear Cell Sarcoma Malignant Rhabdoid Tumor Prune Belly Syndrome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Further Reading

Book

  1. Baert AL (ed) (2008) Encyclopedia of diagnostic imagins. Springer, Berlin/Heidelberg/New YorkGoogle Scholar
  2. Davidson A (1994) Radiology of the kidney and genitourinary tract. W.B. Saunders, Washington, DCGoogle Scholar
  3. Donnelly LF et al, ed. (2005) Diagnostic imaging: Pediatrics. Salt Lake City, AMIRISYS (Philadelphia: Elsevier)Google Scholar
  4. Douglas Stephens F, Durhan Smith E, Hutson JM, Douglas Stephens F, Durhan Smith E, Hutson JM (2002) Congenital anomalies of the kidney, urinary and genital tracts, vol 14, 2nd edn. Martin Dunitz, London, pp 167–307Google Scholar
  5. Murphy WM et al, eds. (2004) Kidney tumors in children. In: Atlas of tumor pathology, 4th Series, Fascicle 1. Armed Forces Institute of Pathology, Washington, DC, pp 47–49Google Scholar
  6. Richardson MD, Warnock DW (2003) Fungal infection: diagnosis and management. Blackwell, MaldenGoogle Scholar
  7. Siegel MJ (1999) The kidney. In: Pediatric body CT. Lippincott Williams & Wilkins, Philadelphia, pp 226–252Google Scholar
  8. Slovis Thomas L. Haller Jack. Caffey’s pediatric diagnostic imaging. Part V, Neonatal genitourinary tract, 10th edn. Mosby, PhiladelphiaGoogle Scholar
  9. Stephen RE (1992) Handbook of gastrointestinal and genitourinary radiology. Mosby, St. Louis, p 180Google Scholar
  10. Swischuk LE (1997) Imaging of the newborn, infant, and young child, 4th edn. Lippincott Williams & Wilkins, Philadelphia, p 608Google Scholar

Articles

  1. Agrons GA, Kingsman KD, Wagner BJ, Sotelo-Avila C (1997) Rhabdoid tumor of the kidney in children: a comparative study of 21 cases. AJR 168:447–451PubMedGoogle Scholar
  2. Alonso RC, Nacenta SB, Martinez PD, Guerrero AS, Fuentes CG (2009) Kidney in danger: CT findings of blunt and penetrating renal trauma. RadioGraphics 29:2033–2053PubMedGoogle Scholar
  3. Amar AM, Tomlinson G, Green DM, Breslow NE, de Alarcon PA (2001) Clinical presentation of rhabdoid tumors of the kidney. J Pediatr Hematol Oncol 23:105–108PubMedGoogle Scholar
  4. Amoury RA, Fellows RA, Goodwin CD, Hall RT, Holder TM, Ashcraft KW (1977) Megacystis-microcolon-intestinal hypoperistalsis syndrome: a cause of intestinal obstruction in the newborn period. J Pediatr Surg 12:1063–1065PubMedGoogle Scholar
  5. Andres V, Muro D, Sanguesa C, Torres D, Berbel Tornero O (2003) Ecografía en el diagnóstico de la candidiasis renal neonatal. Radiología 45:37–42Google Scholar
  6. Angulo JC, Lopez JI, Ereno C, Unda M, Flores N (1991) Hydrops fetalis and congenital mesoblastic nephroma. Child Nephrol Urol 11:115–116PubMedGoogle Scholar
  7. Avni FE, Nicaise N, Hall M, Janssens F, Collier F, Matos C, Metens T (2001) The role of MR imaging for the assessment of complicated duplex kidneys in children: preliminary report. Pediatr Radiol 31:215–223PubMedGoogle Scholar
  8. Babyn P, Owens C, Gyepes M, D’Angio GJ (1995) Imaging patients with Wilms tumor. Hematol Oncol Clin North Am 9:1217–1252PubMedGoogle Scholar
  9. Berdon WE, Baker DH, Blanc WA, Gay B, Santulli TV, Donovan C (1976) Megacystis-microcolon-intestinal hypoperistalsis syndrome: a new case of intestinal obstruction in a newborn. Report of radiological findings in five newborn girls. AJR 126:957–964PubMedGoogle Scholar
  10. Bisset GS, Strife JL (1987) The duplex collecting system in girls with urinary tract infection: prevalence and significance. AJR 148:497–500PubMedGoogle Scholar
  11. Boldus R, Brown R, Culp D (1972) Fungus balls in the renal pelvis. Radiology 102:555–557PubMedGoogle Scholar
  12. Bravo-Bravo C, Martínez-León MI, Ceres-Ruiz L, Weil-Lara B (2003) Childhood xanthogranulomatous pyelonephritis: an uncommon entity. Radiología 45(5):225–227Google Scholar
  13. Carrico C, Lebowitz RL (1998) Incontinence due to an infrasphincteric ectopic ureter: why the delay in diagnosis and what the radiologist can do about it. Pediatr Radiol 28:942–949PubMedGoogle Scholar
  14. Castell V, Muro MD, Brugger S, Moreno A, Sangüesa C (2004) Radiological manifestations of mesoblastic nephroma. Radiología 46:77–82Google Scholar
  15. Chen CP, Wang TY, Chuang CY (1998) Sonographic findings in a fetus with megacystis-microcolon-intestinal hypoperistalsis syndrome. J Clin Ultrasound 26:217–220PubMedGoogle Scholar
  16. Chung-Pin S, Yiu-Wah L, Yang-Jann L, Cheng-Shen H (1998) Bilateral congenital cysts of the seminal vesicle wiyh bilateral duplex kidneys. J Urol 160:184–185Google Scholar
  17. Ciftci AO, Cook RC, van Velzen D (1996) Megacystis microcolon intestinal hypoperistalsis syndrome: evidendency of a primary myocellular defect of contractile fiber synthesis. J Pediatr Surg 31:1706–1711PubMedGoogle Scholar
  18. Craig WD, Wagner BJ, Travis MD (2008) Pyelonephritis: radiologic–pathologic review. RadioGraphics 28:255–277PubMedGoogle Scholar
  19. De Campo JF (1986) Ultrasound of Wilms’ tumor. Pediatr Radiol 16:21–24PubMedGoogle Scholar
  20. Eeg KR, Khoury AE, Halachmi S, Braga LH, Farhat WA, Bägli DJ, Pippi Salle JL, Lorenzo AJ (2009) Single center experience with application of the ALARA concept to serial imaging studies after blunt renal trauma in children – is ultrasound enough? J Urol 181:1834–1840PubMedGoogle Scholar
  21. El-Husseini TK, Egail SA, Al-Orf AM, Mostert C (2005) Ossifying renal tumor of infancy. Saudi Med J 26(12):1978–1979PubMedGoogle Scholar
  22. Ellisen LW (2002) Regulation of gene expression by WT1 in development and tumorigenesis. Int J Hematol 76:110–116PubMedGoogle Scholar
  23. Fan CM, Whitman GJ, Chew FS, Chew FS (1995) Xanthogranulomatous pyelonephritis. AJR 165:1008PubMedGoogle Scholar
  24. Fernbach SK, Feinstein KA, Spencer K, Lindstrom CA (1997) Ureteral duplication and its complications. RadioGraphics 17:109–127PubMedGoogle Scholar
  25. Garza S, Keeney SE, Angel CA, Thompson LL, Swischuk LE (2004) Meconium obstruction in the very low birth weight premature infant. Pediatrics 114:285–290Google Scholar
  26. Geller E, Smergel E, Lowry P (1997) Renal neoplasms of childhood. Rad Clin North Am 35:1391–1413Google Scholar
  27. Glick RD, Hicks MJ, Nuchtern JG, Wesson DE, Olutoye OO, Cass DL (2004) Renal tumors in infants less than 6 months of age. J Pediatr Surg 39(4):522–525PubMedGoogle Scholar
  28. Gonzalez F, Canning DA, Hyun G, Casale P (2006) Lower pole pelvi-ureteric junction obstruction in duplicated collecting systems. BUJ Int 97:161–165Google Scholar
  29. Guillén G, Asensio M, Piró C, Martin JA, Pérez M (2007) Five years of renal trauma in a paediatric trauma center: new tools in the diagnostic and therapeutic process. Cir Pediátr 20:209–214PubMedGoogle Scholar
  30. Haas JE, Palmer NF, Weinberg AG, Beckwith JB (1981) Ultrastructure of malignant rhabdoid tumor of the kidney. A distinctive renal tumor of children. Hum Pathol 12(7):646–657PubMedGoogle Scholar
  31. Hallscheidt PJ, Fink C, Haferkamp A, Bock M, Luburic A, Zuna I, Noeldge G, Kauffmann G (2005) Preoperative staging of renal cell carcinoma with inferior vena cava thrombus using multidetector CT and MRI: prospective study with histopathological correlation. J Comput Assist Tomogr 29:64–68PubMedGoogle Scholar
  32. Hammedeh MY, Buik RG, Nicholls G, Calder CJ, Corkery JJ (1994) Xanthogranulomatous pyelonephritis in childhood: preoperative diagnosis is possible. Br J Urol 73:83–86Google Scholar
  33. Han TI, Kim MJ, Yoon HK, Chung JY, Choeh K (2001) Rhabdoid tumour of the kidney: imaging findings. Pediatr Radiol 31:233–237PubMedGoogle Scholar
  34. Harms D, Gutjahr P, Hohenfellner R, Willke E (1980) Fetal rhabdomyomatous nephroblastoma with a renal pelvic mass simulating sarcoma botryoides. Eur J Pediatr 133(2):167–172PubMedGoogle Scholar
  35. Hayes WS, Hartman DS, Sesterbenn IA (1991) Xanthogranulomatous pyelonephritis. RadioGraphics 11:485–498PubMedGoogle Scholar
  36. Hussman DA, Allen TD (1991) Resolution of vesicoureteral reflux in completely duplicated systems: fact or fiction? J Urol 145:1022–1023Google Scholar
  37. Irsutti M, Puget C, Baunin C, Duga I, Sarramon MF, Guitard J (2000) Mesoblastic nephroma: prenatal ultrasonographic and MRI features. Pediatr Radiol 30:147–150PubMedGoogle Scholar
  38. Johnson KC, Barone JG (2006) Management of obstructing fungal pyelonephritis in infants. Urology 67(2):424, e7-424.e9PubMedGoogle Scholar
  39. Joseph JM, Suter OC, Nenadov-Beck M, Gudinchet F, Frey P, Meagher-Villemure K (2003) Repeated surgical excision for an unusual variant of nephroblastoma: case report and review of the literature. J Pediatr Surg 38(4):E13PubMedGoogle Scholar
  40. Karlowicz MG (2003) Candidal renal and urinary tract infection in neonates. Semin Perinatol 27(5):393–400PubMedGoogle Scholar
  41. Kawashima A, Sandler C, Goldman S (1997) CT of renal inflammatory disease. RadioGraphics 17:851–866PubMedGoogle Scholar
  42. Kawashima A, Sandler CM, Corl FM, West OC, Tamm EP, Fishman EK, Goldman SM (2001) Imaging of renal trauma: a comprehensive review. RadioGraphics 21:557–574PubMedGoogle Scholar
  43. Kelner M, Droullé P, Didier F, Hoeffel JC (2003) The vascular “ring” in mesoblastic nephroma: report of two cases. Pediatr Radiol 33:123–128PubMedGoogle Scholar
  44. Körner M, Krötz MM, Degenhart C, Pfeifer KJ, Reiser MF, Linsenmaier U (2008) Current role of emergency US in patients with major trauma. RadioGraphics 28:225–242PubMedGoogle Scholar
  45. Lefi M, Jouini R, Guesmi M, Mekki M, Belghith M, Nouri A (2002) Congenital mesoblastic nephroma. Prog Urol 12:663–665PubMedGoogle Scholar
  46. Leroy S, Vantalon S, Larakeb A (2010) Vesicoureteral reflux in children with urinary tract infection. Radiology 255:890–898PubMedGoogle Scholar
  47. Loffroy R, Guiu B, Watfa J, Michel F, Cercueil JP, Krause D (2007) Xanthogranulomatous pyelonephritis in adults: clinical and radiological findings in difuse and focal forms. Clin Radiol 62:884–890PubMedGoogle Scholar
  48. Lonergan GJ, Martinez-Leon MI, Agrons GA, Montemarano H, Suarez ES (1998) Nephrogenic rest, nephroblastomatosis and associated lesions of the kidney. RadioGraphics 18:947–968PubMedGoogle Scholar
  49. López-Medina A, Ereno MJ, Fernández-Cantón G, Calder CJ, Zuazo A (1995) Focal xanthogranulomatous pyelonephritis simulating malignancy in children. Abdom Imaging 20:270–271PubMedGoogle Scholar
  50. Lougué-Sorgho LC, Lambot K, Gorincour G, Chaumoître K, Chapuy S, Bourlière-Najean B et al (2006) Kidney trauma in children: state of the art medical imaging. J Radiol 87:275–283PubMedGoogle Scholar
  51. Lowe LH, Isuani BH, Heller RM, Stein SM, Johnson JE, Navarro OM et al (2000a) Pediatric masses: Wilms tumor and beyond. RadioGraphics 20:1585–1603PubMedGoogle Scholar
  52. Lowe LH, Isuani BH, Heller RM, Stein SM, Johnson JE, Navarro OM, Hernanz-Schulman M (2000b) Pediatric renal masses: Wilms tumor and beyond. RadioGraphics 20:1585–1603PubMedGoogle Scholar
  53. Lowe LH, Isuani B, Heller R, Stein S, Johnson J, Navarro O (2000c) Pediatric renal masses: Wilms tumor and beyond. Radio­Graphics 20:1585–1603PubMedGoogle Scholar
  54. Maes P, Delemarre J, de Kraker J, Ninane J (1999) Fetal rhabdomyomatous nephroblastoma: a tumour of good prognosis but resistant to chemotherapy. Eur J Cancer 35(9):1356–1360PubMedGoogle Scholar
  55. McGahan PJ, Richards JR, Bair AE, Rose JS (2005) Ultrasound detection of blunt urological trauma: a 6-year study. Injury 36:762–770PubMedGoogle Scholar
  56. McHugh K (2007) Renal and adrenal tumours in children. Cancer Imaging 7:41–51PubMedCentralPubMedGoogle Scholar
  57. Mekki M, Belghith M, Krichène I, Zakhama A, Landolsi A, Chelly S, Nouri A (2002) Fetal rhabdomyomatous nephroblastoma: report of 2 cases and review of the literature. Ann Urol (Paris) 36(4):245–249Google Scholar
  58. Murthi GV, Carachi R, Howatson A (2003) Congenital cystic mesoblastic nephroma. Pediatr Surg Int 19:109–111PubMedGoogle Scholar
  59. Nakagawa T, Misawa H, Nakajima Y, Takaki M (2005) Absence of peristalsis in the ileum of W/W(V) mutant mice that are selectively deficient in myenteric interstitial cells of Cajal. J Smooth Muscle Res 41:141–151PubMedGoogle Scholar
  60. Nguyen MM, Das S (2002) Pediatric renal trauma. Urology 59:762–767PubMedGoogle Scholar
  61. Noyola DE, Fernandez M, Moylett EH, Baker CJ (2001) Ophthalmologic, visceral, and cardiac involvement in neonates with candidemia. Clin Infect Dis 32(7):1018–1023PubMedGoogle Scholar
  62. Pickhardt PJ, Lonergan GJ, Davis CJ, Kashitani N, Eagner BJ (2000a) From the archives of the AFIP. Infiltrative renal lesions: radiologic-pathologic correlation. RadioGraphics 20:215–243PubMedGoogle Scholar
  63. Pickhardt PJ, Lonergan GJ, Kashitani N, Wagner BJ (2000b) Infiltrative renal lesions: radiologic and pathologic correlation. RadioGraphics 20:215–243PubMedGoogle Scholar
  64. Pollono D, Drut R, Tomarchio S, Fontana A, Ibañez O (2003) Fetal rhabdomyomatous nephroblastoma: report of 14 cases confirming chemotherapy resistance. J Pediatr Hematol Oncol 25(8):640–643PubMedGoogle Scholar
  65. Porteus MH, Narkool P, Neuberg D, Guthrie KN, Breslow DM (2000) Characteristics and outcome of children with Beckwith–Wiedemann syndrome and Wilms’ tumor: A report from the National Wilms Tumor Study Group. JCO 18:2026–2037Google Scholar
  66. Privett JT, Jeans WD, Roylance J (1976) The incidence and importance of renal duplication. Clin Radiol 4:521–530Google Scholar
  67. Quinn FM, Dick AC, Corbally MT, McDermott MB, Guiney EJ (1999) Xanthogranulomatous pyelonephritis in childhood. Arch Dis Child 81:483–486PubMedGoogle Scholar
  68. Riebel T, Kebelmann-Betzing C, Sarioglu N, Wit J, Seeger K (2003) Unusual mesoblastic nephroma in a young child. Pediatr Radiol 33:62–65PubMedGoogle Scholar
  69. Rite Gracia S, Fernández Álvarez de Sotomayor B, Rebage Moisés V, Marco Tello A, Esteban Ibarz JA et al (2000) Megabladder–microcolon–intestinal hypoperistalsis syndrome. An Esp Pediatr 53(3):253–256PubMedGoogle Scholar
  70. Roberts CW, Biegel JA (2009) The role of SMARCB1/INI1 in development of rhabdoid tumor. Cancer Biol Ther 8:412–416PubMedCentralPubMedGoogle Scholar
  71. Rolle U, Piaseczna-Piotrowska A, Puri P (2007) Interstitial cells of Cajal in the normal gut and in intestinal motility disorders of childhood. Pediatr Surg Int 23:1139–1152PubMedGoogle Scholar
  72. Saba LM, de Camargo B, Gabriel-Arana M (1998) Experience with six children with fetal rhabdomyomatous nephroblastoma: review of the clinical, biologic, and pathologic features. Med Pediatr Oncol 30(3):152–155PubMedGoogle Scholar
  73. Samuel M, Duffy P, Capps S, Mouriquand P, Williams D, Ransley P (2001) Xanthogranulomatous pyelonephritis in childhood. J Pediatr Surg 36:598–601PubMedGoogle Scholar
  74. Sato M, Yoshii H (2004) Reevaluation of ultrasonography for solid-organ injury in blunt abdominal trauma. J Ultrasound Med 23:583–596Google Scholar
  75. Schelling J, Schröder A, Stein R, Rösch WH (2007) Ossifying renal tumor of infancy. J Pediatr Urol 3(3):258–261PubMedGoogle Scholar
  76. Schenk JP, Graf N, Günther P, Ley S, Göppl M, Kulozik A, Rohrschneider WK, Tröger J (2008) Role of MRI in the management of patients with nephroblastoma. Eur Radiol 18:683–691PubMedGoogle Scholar
  77. Seixas-Mikelus SA, Khan A, Williot PE, Greenfield SP (2009) Three-month-old boy with juvenile granulosa cell tumor of testis and ossifying renal tumor of infancy. Urology 74(2):311–313PubMedGoogle Scholar
  78. Shinohara N, Koanagi T, Hanioka K (1998) Ossifying renal tumor of infancy: the first Japanese case with long-term follow-up. Patol Int 48:151–159Google Scholar
  79. Siegel MJ, Chung EM (2008) Wilms’ tumor and other pediatric renal masses. Magn Reson Imaging Clin N Am 16:479–497PubMedGoogle Scholar
  80. Siomou E, Papadopoulou F, Kollios KD et al (2006) Duplex collecting system diagnosed during the first 6 years of life after a first urinary tract infection: a study of 63 children. J Urol 175:678–681PubMedGoogle Scholar
  81. Sister CL, Siegel MJ (1989) Malignant rhabdoid tumor of the kidney: radiologic features. Radiology 172:211–212Google Scholar
  82. Sotelo-Avila C et al (1995) Ossifying renal tumor of infancy: a clinicopathologic study of nine cases. Pediatr Pathol Lab Med 15:745–762PubMedGoogle Scholar
  83. Steffens J, Kraus J, Misho B, Remberger K (1993) Ossifying renal tumor of infancy. J Urol 149(5):1080–1081PubMedGoogle Scholar
  84. Stokland E, Jodal U, Sixt R, Swerkersson S, Hansson S (2007) Uncomplicated duplex kidney and DMSA scintigraphy in children with urinary tract infection. Pediatr Radiol 37:826–828PubMedGoogle Scholar
  85. Umbreit EC, Routh JC, Husmann DA (2009) Nonoperative management of nonvascular grade IV blunt renal trauma in children: meta-analysis and systematic review. Urology 74:579–582PubMedGoogle Scholar
  86. Vasquez T (2009) Epidemiología clínica del micetoma renal por Candida. Rev Enfer Infec Pediatr 22(89):6Google Scholar
  87. Vazquez JL, Barnewolt CE, Shamberger RC, Chung T, ­Perez-Atayde AR (1998) Ossifying renal tumor of infancy presenting as a palpable abdominal mass. Pediatr Radiol 28:454–457PubMedGoogle Scholar
  88. Vázquez O, Campos Rivera T, Jiménez R, Ahumada Mendoza H, Martínez I (2001) Candidiasis renal en pacientes pediátricos. Rev Mex Patol Clin 48(1):17–22Google Scholar
  89. Vicandi B, Picazo ML, González MC, Contreras F (1985) Fetal rhabdomyomatous nephroblastoma: study of 2 cases and review of the literature. An Esp Pediatr 23(3):205–210PubMedGoogle Scholar
  90. Vujanic GM (2006) Renal tumors in early life. Curr Diagn Pathol 12:210–219Google Scholar
  91. Vujanic GM, Charles AK (2008) Renal tumours of childhood: an update. Pathology 40:217–227PubMedGoogle Scholar
  92. Vujanic GM, Sandstedt B, Harms D, Boccon-Gibod L, Delemarre JF (1996) Rhabdoid tumour of the kidney: a clinicopahological study of 22 patiens from the International Society of Paedia­tric Oncology (SIOP) nephroblastoma file. Histopatho­logy 28:333–340PubMedGoogle Scholar
  93. Weese DL, Applebaum H, Taber P (1991) Mapping intravascular extension of Wilms’ tumor with magnetic resonance imaging. J Pediatr Surg 26:64–67PubMedGoogle Scholar
  94. Wigger HJ (1976) Fetal rhabdomyomatous nephroblastoma-a variant of Wilms tumor. Hum Pathol 7(6):613–623PubMedGoogle Scholar
  95. Wimalendra M, Reece A, Nicholl RM (2004) Renal fungal ball. Arch Dis Child Fetal Neonatal Ed 89(4):F376PubMedGoogle Scholar
  96. Winger DI, Buyuk A, Bohrer S, Turi G, Scimeca P, Price A et al (2006) Radiology–pathology conference: rhabdoid tumor of the kidney. Clin Imaging 30:132–136PubMedGoogle Scholar
  97. Winter RM, Knowles SAS (1986) Megacystis-­microcolon-intestinal hipoperistalsis syndrome: confirmation of autosomal recessive inheritance. J Med Genet 23:3260–3262Google Scholar
  98. Yigit S, Barlas C, Yurdakok M, Onderoglu L, Zafer Y, Saltik I (1996) The megacystis-microcolon-intestinal hypoperistalsis syndrome: report of a case and review of the literature. Turk J Pediatr 38:137–141PubMedGoogle Scholar
  99. Zarate YA, Mena R, Martin LJ, Steele P, Tinkle BT, Hopkin RJ (2009) Experience with hemihyperplasia and Beckwith–Wiedemann syndrome surveillance protocol. Am J Med Genet A 149:1691–1697Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  • María I. Martínez León
    • 1
  • Juan E. Gutiérrez
    • 2
  • Luisa Ceres Ruiz
    • 3
  1. 1.Radiology Department Pediatric Radiology UnitHospital Materno-Infantil del C.H.U. Carlos HayaMálagaSpain
  2. 2.Health Science CenterUniversity of TexasSan AntonioUSA
  3. 3.Radiology Department Pediatric Radiology Unit. ChiefHospital Materno-Infantil del C.H.U. Carlos HayaMálagaSpain

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