Abstract
Global and regional cardiac deformation provides important information on myocardial (dys-)function in a variety of clinical settings. Recent developments in the field of echocardiography have allowed the cardiologist to quantify cardiac deformation in a non-invasive manner. Unstitched volumetric data can be captured in a high frame rate by real-time ultrasound imaging. However, most existing methods for measuring myocardial mechanics are often limited to measurements in one or two dimensions. Since myocardial tissue is virtually incompressible, the ventricular wall contains the same volume during the cardiac cycle and, thus, deforms in three dimensions. In this paper, we propose an automatic method to estimate the regional 3D myocardial mechanics on ultrasound images by recovering the 3D non-rigid deformation of the myocardium. The key advantage of our method is fusing multiple information, such as speckle patterns, image gradients, boundary detection, and motion prediction, to achieve a robust tracking on 3D+t ultrasound data. Preliminary results in both in-vitro and in-vivo experiments confirmed these findings in a quantitative manner, as the motion and mechanical parameters, such as displacement and strain, estimated by our method are close to both the ground-truth data and the clinical evaluation. The proposed method is efficient and achieves high speed performance of less than 1 second per frame for volumetric ultrasound data.
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D’hooge, J., Heimdal, A., Jamal, F., Kukulski, T., Bijnens, B., Rademakers, F., Hatle, L., Suetens, P., Sutherland, G.R.: Regional strain and strain rate measurements by cardiac ultrasound: Principles, implementation and limitations. Eur. J. Echocardiogr. 1(3), 154–170 (2000)
Hatle, L., Sutherland, G.: Regional myocardial function a new approach. Eur. Heart J. 21, 1337–1357 (2000)
Chung, E., Leon, A., Tavazzi, L., Sun, J., Nihoyannopoulos, P., Merlino, J., Abraham, W.T., Ghio, S., Leclercq, C., Bax, J., Yu, C., Gorcsan III, J., St. John Sutton, M., De Sutter, J., Murillo, J.: Results of the predictors of response to crt (PROSPECT) trial. Circulation 117, 2608–2616 (2008)
Kaluzynski, K., Chen, X., Emelianov, S., Skovoroda, A., O’Donnell, M.: Strain rate imaging using two-dimensional speckle tracking. Transactions on Ultrasonics, Ferroelectrics and Frequency Control 48(4), 1111–1123 (2001)
Suffoletto, M., Dohi, K., Cannesson, M., Saba, S., Gorcsan, J.: Novel speckle-tracking radial strain from routine black-and-white echocardiographic images to quantify dyssynchrony and predict response to cardiac resynchronization therapy. Circulation 113(7), 960–968 (2006)
Ledesma-Carbayo, M.J., Kybic, J., Desco, M., Santos, A., Suhling, M., Hunziker, P., Unser, M.: Spatio-temporal nonrigid registration for ultrasound cardiac motion estimation. IEEE Trans. Medical Imaging 24(9), 1113–1126 (2005)
Yin, F.C.P., Chan, C.C.H., Judd, R.M.: Compressibility of perfused passive myocardium. American journal of physiology. Heart and circulatory physiology 271(5), 1864–1870 (1996)
Zhu, Y., Papademetris, X., Duncan, J.S., Sinusas, A.J.: Cardiac MR image segmentation with incompressibility constraint. In: ISBI, pp. 185–188 (2007)
Glass, L., Hunter, P., McCulloch, A.: Theory of Heart: Biomechanics, Biophysics, and Nonlinear Dynamics of Cardiac Function. Springer, New York (1991)
Amini, A., Chen, Y., Curwen, R., Manu, V., Sun, J.: Coupled b-snake grides and constrained thin-plate splines for analysis of 2d tissue deformations from tagged mri. TMI 17(3), 344–356 (1998)
Leung, K.Y.E., van Stralen, M., van Burken, G., de Jong, N., Bosch, J.G.: Automatic active appearance model segmentation of 3D echocardiograms. In: ISBI, pp. 320–323 (2010)
Grau, V., Becher, H., Noble, J.: Registration of multiview real-time 3-D echocardiographic sequences. TMI 26(9), 1154–1165 (2007)
Elen, A., Choi, H.F., Loeckx, D., Gao, H., Claus, P., Suetens, P., Maes, F., D’hooge, J.: Three-dimensional cardiac strain estimation using spatio-temporal elastic registration of ultrasound images: A feasibility study. TMI 27(11), 1580–1591 (2008)
Craene, M.D., Camara, O., Bijnens, B.H., Frangi, A.F.: Large diffeomorphic FFD registration for motion and strain quantification from 3D-US sequences. In: Ayache, N., Delingette, H., Sermesant, M. (eds.) FIMH 2009. LNCS, vol. 5528, pp. 437–446. Springer, Heidelberg (2009)
Duan, Q., Parker, K.M., Lorsakul, A., Angelini, E.D., Hyodo, E., Homma, S., Holmes, J.W., Laine, A.F.: Quantitative validation of optical flow based myocardial strain measures using sonomicrometry. In: ISBI, pp. 454–457 (2009)
Zheng, Y., Barbu, A., Georgescu, B., Scheuering, M., Comaniciu, D.: Four-chamber heart modeling and automatic segmentation for 3-D cardiac CT volumes using marginal space learning and steerable features. TMI 27(11), 1668–1681 (2008)
Tu, Z.: Probabilistic boosting-tree: Learning discriminative models for classification, recognition, and clustering. In: ICCV, pp. II: 1589–1596 (2005)
Zhu, Y., Papademetris, X., Sinusas, A.J., Duncan, J.S.: A dynamical shape prior for LV segmentation from RT3D echocardiography. In: Yang, G.-Z., Hawkes, D., Rueckert, D., Noble, A., Taylor, C. (eds.) MICCAI 2009. LNCS, vol. 5761, pp. 206–213. Springer, Heidelberg (2009)
Yang, L., Georgescu, B., Zheng, Y., Foran, D.J., Comaniciu, D.: A fast and accurate tracking algorithm of left ventricles in 3D echocardiography. In: ISBI (2008)
Chen, X., Xie, H., Erkamp, R., Kim, K., Jia, C., Rubin, J.M., O’Donnell, M.: 3-D correlation-based speckle tracking. Ultrasonic Imaging 27, 21–36 (2005)
Wang, X., Chen, T., Zhang, S., Metaxas, D., Axel, L.: LV motion and strain computation from tMRI based on meshless deformable models. In: Metaxas, D., Axel, L., Fichtinger, G., Székely, G. (eds.) MICCAI 2008, Part I. LNCS, vol. 5241, pp. 636–644. Springer, Heidelberg (2008)
Yang, L., Georgescu, B., Zheng, Y., Meer, P., Comaniciu, D.: 3D ultrasound tracking of the left ventricles using one-step forward prediction and data fusion of collaborative trackers. In: CVPR (2008)
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Wang, Y., Georgescu, B., Houle, H., Comaniciu, D. (2010). Volumetric Myocardial Mechanics from 3D+t Ultrasound Data with Multi-model Tracking. In: Camara, O., Pop, M., Rhode, K., Sermesant, M., Smith, N., Young, A. (eds) Statistical Atlases and Computational Models of the Heart. STACOM 2010. Lecture Notes in Computer Science, vol 6364. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-15835-3_19
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DOI: https://doi.org/10.1007/978-3-642-15835-3_19
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