Abstract
Prostate cancer is a major health threat for men. For over five years, the U.S. National Cancer Institute has performed prostate biopsies with a magnetic resonance imaging (MRI)-guided robotic system. Purpose: A retrospective evaluation methodology and analysis of the clinical accuracy of this system is reported. Methods: Using the pre and post-needle insertion image volumes, a registration algorithm that contains a two-step rigid registration followed by a deformable refinement was developed to capture prostate dislocation during the procedure. The method was validated by using three-dimensional contour overlays of the segmented prostates and the registrations were accurate up to 2 mm. Results: It was found that tissue deformation was less of a factor than organ displacement. Out of the 82 biopsies from 21 patients, the mean target displacement, needle placement error, and clinical biopsy error was 5.9 mm, 2.3 mm, and 4 mm, respectively. Conclusion: The results suggest that motion compensation for organ displacement should be used to improve targeting accuracy.
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Xu, H. et al. (2010). MRI-Guided Robotic Prostate Biopsy: A Clinical Accuracy Validation. In: Jiang, T., Navab, N., Pluim, J.P.W., Viergever, M.A. (eds) Medical Image Computing and Computer-Assisted Intervention – MICCAI 2010. MICCAI 2010. Lecture Notes in Computer Science, vol 6363. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-15711-0_48
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DOI: https://doi.org/10.1007/978-3-642-15711-0_48
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