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Design and Characterization of a Signal Conditioning Microchip and Thin-Film Microelectrode Array for High Spatial Resolution Cardiac Mapping

  • Conference paper
6th World Congress of Biomechanics (WCB 2010). August 1-6, 2010 Singapore

Part of the book series: IFMBE Proceedings ((IFMBE,volume 31))

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Abstract

A Thin-Film Microelectrode Array (TFMEA) capable of recording electrical activities of the heart with high spatial resolution, on the order of individual myocytes, was developed and characterized to study the mechanisms of arrhythmias. A customized multichannel signal conditioning microchip (SCM) consisting of a pre-amplification stage and band-pass filter was interfaced directly to the electrodes on the TFMEA to improve the signal-to-noise ratios (SNRs). The results suggest that the TFMEA-SCM system will greatly enhance the spatial resolution and improve signal quality for high resolution cardiac mapping.

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Author information

Authors and Affiliations

  1. Department of Bioengineering, University of Louisville, Louisville, Kentucky, United States

    Huihang Dong, Thomas Roussel, Steven Koenig & Robert Keynton

  2. Department of Electrical and Computer Engineering, University of Louisville, Louisville, Kentucky, United States

    Huihang Dong, Douglas Jackson & John Naber

  3. Departments of Medicine, Physiology, and Biophysics, University of Alabama at Birmingham, Birmingham, Alabama, United States

    Derek Dosdal & Raymond Ideker

Authors
  1. Huihang Dong
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  2. Douglas Jackson
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  3. Thomas Roussel
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  4. Derek Dosdal
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  5. Raymond Ideker
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  6. John Naber
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  7. Steven Koenig
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  8. Robert Keynton
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Editor information

Editors and Affiliations

  1. Fac. Engineering, Dept. Mechanical Engineering Div. Bioengineering, National University of Singapore , Engineering Drive 7 1 Block, 117574, E3A #04-15, Singapore, Singapore

    C. T. Lim

  2. Dept. Orthopaedic Surgery Tissue Engineering Program, National University of Singapore , Medical Drive 27 Level 4, DSO (Kent Ridge) Bldg., 117510, Singapore, Singapore

    J. C. H. Goh

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© 2010 International Federation for Medical and Biological Engineering

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Cite this paper

Dong, H. et al. (2010). Design and Characterization of a Signal Conditioning Microchip and Thin-Film Microelectrode Array for High Spatial Resolution Cardiac Mapping. In: Lim, C.T., Goh, J.C.H. (eds) 6th World Congress of Biomechanics (WCB 2010). August 1-6, 2010 Singapore. IFMBE Proceedings, vol 31. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-14515-5_361

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  • DOI: https://doi.org/10.1007/978-3-642-14515-5_361

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-14514-8

  • Online ISBN: 978-3-642-14515-5

  • eBook Packages: EngineeringEngineering (R0)

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