Numerical Study of Pulsatile Flow Through Models of Vascular Stenoses with PhysiologicalWaveform of the Heart

  • Jason D. Thompson
  • Christian F. Pinzn
  • Ramesh K. Agarwal
Conference paper
Part of the Lecture Notes in Computational Science and Engineering book series (LNCSE, volume 74)


Recently an in-vitro experimental investigation on axisymmetric models of stenotic arteries was conducted by Peterson and Plesniak to determine the influence of three fundamental disturbances on stenotic flows: a geometric perturbation resulting in asymmetry of stenosis; a skewed mean inlet velocity profile; and flow downstream of a bend (skewed mean inlet velocity profile plus secondary flow due to bend). The goal of this paper is to numerically simulate the flow fields in the experiments of Peterson and Plesniak and compare the computed results with the experimental data. A commercially available CFD flow solver FLUENT is employed in the numerical simulations. The stenosis is modeled as an axisymmetric 75% area reduction occlusion. The actual physiological waveform of the heart is employed at the inlet in both the simulations and the experiments. Computations are in good agreement with the experimental data for flow in an axisymmetric stenosis with 75% area reduction occlusion. Computations for flow in an asymmetric stenosis (due to small geometric perturbation to axisymmetric configuration) are also in reasonable agreement with the experimental data.

Key words

Vascular Stenosis Pulsatile Blood Flow in Arteries 


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Copyright information

© Springer Berlin Heidelberg 2010

Authors and Affiliations

  • Jason D. Thompson
    • 1
  • Christian F. Pinzn
    • 1
  • Ramesh K. Agarwal
    • 1
  1. 1.Mechanical, Aerospace and Structural Engineering DepartmentWashington University in St. LouisSt. LouisUSA

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