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Multimodale Therapie des Analkarzinoms

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Zusammenfassung

Autoren

Strahlentherapie: W. Budach, E. Bölke, C. Matuschek

Viszeralchirurgie: K. Orth

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Literatur

  • Abbas A, Yang G, Fakih M (2010) Management of anal cancer in 2010. Part 1: Overview, screening, and diagnosis. Oncology 24(4):364–369

    PubMed  Google Scholar 

  • Abramowitz L, Mathieu N, Roudot-Thoraval F, Lemarchand N, Bauer P, Hennequin C, Mitry E, Romelaer C, Aparicio T, Sobhani I (2009) Epidermoid anal cancer prognosis comparison among HIV+ and HIV-patients. Aliment Pharmacol Ther 30(4):414–421

    Article  CAS  PubMed  Google Scholar 

  • Ajani JA, Winter KA, Gunderson LL, Pedersen J, Benson AB, Thomas CR Jr., Mayer RJ, Haddock MG, Rich TA, Willett C (2008) Fluorouracil, mitomycin, and radiotherapy vs fluorouracil, cisplatin, and radiotherapy for carcinoma of the anal canal: a randomized controlled trial. JAMA 299(16):1914–1921

    Article  CAS  PubMed  Google Scholar 

  • Bartelink H, Roelofsen F, Eschwege F, Rougier P, Bosset JF, Gonzalez DG, Peiffert D, van Glabbeke M, Pierart M (1997) Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastrointestinal Cooperative Groups. J Clin Oncol 15(5):2040–2049

    CAS  PubMed  Google Scholar 

  • Bazan JG, Hara W, Hsu A, Kunz PA, Ford J, Fisher GA, Welton ML, Shelton A, Kapp DS, Koong AC, Goodman KA, Chang DT (2011) Intensity-modulated radiation therapy versus conventional radiation therapy for squamous cell carcinoma of the anal canal. Cancer 117(15):3342–3351

    Article  PubMed  Google Scholar 

  • Beahrs OH, Wilson SM (1976) Carcinoma of the anus. Ann Surg 184(4):422–428

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  • Josef BE, Moughan J, Ajani JA, Flam M, Gunderson L, Pollock J, Myerson R, Anne R, Rosenthal SA, Willett C (2010) Impact of overall treatment time on survival and local control in patients with anal cancer: a pooled data analysis of Radiation Therapy Oncology Group trials 87-04 and 98-11. J Clin Oncol 28(34):5061–5066

    Article  Google Scholar 

  • Boman BM, Moertel CG, O‘Connell MJ, Scott M, Weiland LH, Beart RW, Gunderson LL, Spencer RJ (1984) Carcinoma of the anal canal. A clinical and pathologic study of 188 cases. Cancer 54(1):114–125

    Article  CAS  PubMed  Google Scholar 

  • Bosset JF, Roelofsen F, Morgan DA, Budach V, Coucke P, Jager JJ, Steen-Banasik E, Triviere N, Stuben G, Puyraveau M, Mercier M (2003) Shortened irradiation scheme, continuous infusion of 5-fluorouracil and fractionation of mitomycin C in locally advanced anal carcinomas. Results of a phase II study of the European Organization for Research and Treatment of Cancer. Radiotherapy and Gastrointestinal Cooperative Groups. Eur J Cancer 39(1):45–51

    Article  CAS  PubMed  Google Scholar 

  • De Vuyst H, Clifford GM, Nascimento MC, Madeleine MM, Franceschi S (2009) Prevalence and type distribution of human papillomavirus in carcinoma and intraepithelial neoplasia of the vulva, vagina and anus: a meta-analysis. Int J Cancer 124(7):1626–1636

    Article  PubMed  Google Scholar 

  • Ellenhorn JD, Enker WE, Quan SH (1994) Salvage abdominoperineal resection following combined chemotherapy and radiotherapy for epidermoid carcinoma of the anus. Ann Surg Oncol 1(2):105–110

    Article  CAS  PubMed  Google Scholar 

  • Flam M, John M, Pajak TF, Petrelli N, Myerson R, Doggett S, Quivey J, Rotman M, Kerman H, Coia L, Murray K (1996) Role of mitomycin in combination with fluorouracil and radiotherapy, and of salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma of the anal canal: results of a phase III randomized intergroup study. J Clin Oncol 14(9):2527–2539

    CAS  PubMed  Google Scholar 

  • Gerard JP, Chapet O, Samiei F, Morignat E, Isaac S, Paulin C, Romestaing P, Favrel V, Mornex F, Bobin JY (2001) Management of inguinal lymph node metastases in patients with carcinoma of the anal canal: experience in a series of 270 patients treated in Lyon and review of the literature. Cancer 92(1):77–84

    Article  CAS  PubMed  Google Scholar 

  • Glynne-Jones R, Northover JM, Cervantes A (2010) Anal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 21(Suppl 5):87–92

    Article  Google Scholar 

  • Horch R, Stelzner F, Jager K, Roosen J (1990) Results of treatment of anal cancer. Zentralbl Chir 115(7):407–414

    CAS  PubMed  Google Scholar 

  • Matthews JH, Burmeister BH, Borg M, Capp AL, Joseph D, Thompson KM, Thompson PI, Harvey JA, Spry NA (2011) T1-2 anal carcinoma requires elective inguinal radiation treatment – the results of Trans Tasman Radiation Oncology Group study TROG 99.02. Radiother Oncol 98(1):93–98

    Article  PubMed  Google Scholar 

  • Nielsen A, Munk C, Kjaer SK (2012) Trends in incidence of anal cancer and high-grade anal intraepithelial neoplasia in Denmark, 1978–2008. Int J Cancer 130(5):1168–1173

    Article  CAS  PubMed  Google Scholar 

  • Nigro ND (1991) The force of change in the management of squamous-cell cancer of the anal canal. Dis Colon Rectum 34(6):482–486

    Article  CAS  PubMed  Google Scholar 

  • Northover J, Glynne-Jones R, Sebag-Montefiore D, James R, Meadows H, Wan S, Jitlal M, Ledermann J (2010) Chemoradiation for the treatment of epidermoid anal cancer: 13-year follow-up of the first randomised UKCCCR Anal Cancer Trial (ACT I). Br J Cancer 102(7):1123–1128

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  • Piketty C, Selinger-Leneman H, Grabar S, Duvivier C, Bonmarchand M, Abramowitz L, Costagliola D, Mary-Krause M (2008) Marked increase in the incidence of invasive anal cancer among HIV-infected patients despite treatment with combination antiretroviral therapy. AIDS 22(10):1203–1211

    Article  PubMed  Google Scholar 

  • Pintor MP, Northover JM, Nicholls RJ (1989) Squamous cell carcinoma of the anus at one hospital from 1948 to 1984. Br J Surg 76(8):806–810

    Article  CAS  PubMed  Google Scholar 

  • Schiller DE, Cummings BJ, Rai S, Le LW, Last L, Davey P, Easson A, Smith AJ, Swallow CJ (2007) Outcomes of salvage surgery for squamous cell carcinoma of the anal canal. Ann Surg Oncol 14(10):2780–2789

    Article  PubMed  Google Scholar 

  • Seo Y, Kinsella MT, Reynolds HL, Chipman G, Remick SC, Kinsella TJ (2009) Outcomes of chemoradiotherapy with 5-Fluorouracil and mitomycin C for anal cancer in immunocompetent versus immunodeficient patients. Int J Radiat Oncol Biol Phys 75(1):143–149

    Article  CAS  PubMed  Google Scholar 

  • Serup-Hansen E, Linnemann D, Skovrider-Ruminski W, Høgdall E, Geertsen PF, Havsteen H (2014) Human papillomavirus genotyping and p16 expression as prognostic factors for patients with American Joint Committee on Cancer stages I to III carcinoma of the anal canal. J Clin Oncol 32(17):1812–1817

    Article  PubMed  Google Scholar 

  • UKCCCR Anal Cancer Trial Working Party (1996) Epidermoid anal cancer: results from the UKCCCR randomised trial of radiotherapy alone versus radiotherapy, 5-fluorouracil, and mitomycin. UK Co-ordinating Committee on Cancer Research. Lancet 348(9034):1049–1054

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Klinik und Poliklinik für Strahlentherapie und Radioonkologie, Universitätsklinikum Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Deutschland

    Wilfried Budach Prof. Dr. med., Edwin Bölke Prof. Dr. med. & Christiane Matuschek Dr. med.

  2. Allgemein- und Visceralchirurgie, Harzkliniken Goslar, Köslinerstraße 12, 38642, Goslar, Deutschland

    Klaus Orth Prof. Dr. med.

Authors
  1. Wilfried Budach Prof. Dr. med.
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  2. Edwin Bölke Prof. Dr. med.
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  3. Christiane Matuschek Dr. med.
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  4. Klaus Orth Prof. Dr. med.
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Editor information

Editors and Affiliations

  1. Medizinische Klinik, Florence-Nightingale-Krankenhaus, Düsseldorf, Germany

    J.F. Erckenbrecht

  2. Klinik für Hepato-Pankreato-Biliäre Chirurgie, 310Klinik Nürnberg, Nürnberg, Germany

    Sven Jonas

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Budach, W., Bölke, E., Matuschek, C., Orth, K. (2015). Multimodale Therapie des Analkarzinoms. In: Erckenbrecht, J., Jonas, S. (eds) Viszeralmedizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-14301-4_35

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  • DOI: https://doi.org/10.1007/978-3-642-14301-4_35

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-14300-7

  • Online ISBN: 978-3-642-14301-4

  • eBook Packages: Medicine (German Language)

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