Abstract
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Esophageal cancer is the seventh leading cause of cancer deaths worldwide, with squamous cell responsible for 95% of all cases.
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Adenocarcinoma now accounts for over 50% of esophageal cancer in the USA, due to association with gastroesophageal reflux disease (GERD) and obesity.
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Dysphagia and weight loss are the two most common presentations in patients with esophageal cancer.
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Endoscopic ultrasound (EUS) is necessary to accompany a complete workup for proper staging and diagnosis of esophageal cancer.
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Surgery is the standard of care for early-stage esophageal cancer.
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Preoperative chemotherapy and radiation is the standard option for locally advanced esophageal cancer in surgically eligible patients.
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Pathologic complete response is around 25% after preoperative chemoradiation, which improves survival.
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Definitive chemoradiation cures some patients with esophageal cancer.
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The need to add surgical resection after chemoradiation is controversial, and may not be needed for selected patients.
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© 2011 Springer-Verlag Berlin Heidelberg
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Lin, S., Liao, Z. (2011). Esophageal Cancer. In: Lu, J., Brady, L. (eds) Decision Making in Radiation Oncology. Medical Radiology(), vol 0. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-13832-4_12
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DOI: https://doi.org/10.1007/978-3-642-13832-4_12
Publisher Name: Springer, Berlin, Heidelberg
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Online ISBN: 978-3-642-13832-4
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