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An Application for Studying Tandem Repeats in Orthologous Genes

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Book cover Advances in Bioinformatics

Part of the book series: Advances in Intelligent and Soft Computing ((AINSC,volume 74))

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Abstract

Several authors have being suggesting that the occurrence of amino acids repeats in some genes are implied in human diseases. We aim to investigate if these repetitions, which one can observe in humans, also exist in orthologous genes of several organisms, and how they have evolved along time. However, for this kind of study, it is necessary to use different databases and computation methods that are not integrated in any specific tool. In this paper, we present a bioinformatics application, supported by Web Services, that allows to conduct comparative analysis studies for various organisms, along the evolutionary chain.

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Lousado, J.P., Oliveira, J.L., Moura, G., Santos, M.A.S. (2010). An Application for Studying Tandem Repeats in Orthologous Genes. In: Rocha, M.P., Riverola, F.F., Shatkay, H., Corchado, J.M. (eds) Advances in Bioinformatics. Advances in Intelligent and Soft Computing, vol 74. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-13214-8_14

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  • DOI: https://doi.org/10.1007/978-3-642-13214-8_14

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-13213-1

  • Online ISBN: 978-3-642-13214-8

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