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Reconstruction of Upper Cervical Spine and Craniovertebral Junction

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Abstract

At the craniovertebral junction (CVJ) and upper cervical spine (UCS) regions, many types of tumors can be seen;however, the incidence is very low. Using an oncological classification, they can be divided into the general categories of tumors of bone, tumors of connective tissue, and tumors of neural structures. More commonly in practice, surgeons use classifications common in the other parts of spine. Thus, it primarily starts with defining the tumors as intradural or extradural. Within the intradural classification it is further divided into intramedullary and extramedullary tumors. Tumors that are located extradurally usually consist of primary and secondary tumors of bone and connective tissue. Therapy for these tumors is type dependent and can vary from observation only to complicated, multidisciplinary surgical procedures followed by chemo and radiotherapy.

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References

  1. Abdu, W.A., Provencher, M.: Primary bone and metastatic tumors of the cervical spine. Spine (Phila Pa 1976) 23, 2767–2777 (1998)

    CAS  Google Scholar 

  2. Abe, E., Sato, K., Tazawa, H., et al.: Total spondylectomy for primary tumor of the thoracolumbar spine. Spinal Cord 38, 146–152 (2000)

    Article  CAS  PubMed  Google Scholar 

  3. Ameli, N.O., Abbassioun, K., Saleh, H., et al.: Aneurysmal bone cysts of the spine. Report of 17 cases. J Neurosurg 63, 685–690 (1985)

    Article  CAS  PubMed  Google Scholar 

  4. Amendola, B.E., Amendola, M.A., Oliver, E., et al.: Chordoma: role of radiation therapy. Radiology 158, 839–843 (1986)

    CAS  PubMed  Google Scholar 

  5. Atanasiu, J.P., Badatcheff, F., Pidhorz, L.: Metastatic lesions of the cervical spine. A retrospective analysis of 20 cases. Spine (Phila Pa 1976) 18, 1279–1284 (1993)

    CAS  Google Scholar 

  6. Azouz, E.M., Kozlowski, K., Marton, D., et al.: Osteoid osteoma and osteoblastoma of the spine in children. Report of 22 cases with brief literature review. Pediatr Radiol 16, 25–31 (1986)

    Article  CAS  PubMed  Google Scholar 

  7. Bacci, G., Toni, A., Avella, M., et al.: Long-term results in 144 localized Ewing’s sarcoma patients treated with combined therapy. Cancer 63, 1477–1486 (1989)

    Article  CAS  PubMed  Google Scholar 

  8. Bailey, C.S., Fisher, C.G., Boyd, M.C., et al.: En bloc marginal excision of a multilevel cervical chordoma. Case report. J Neurosurg Spine 4, 409–414 (2006)

    Article  PubMed  Google Scholar 

  9. Barsa, P., Suchomel, P., Lukas, R., et al.: Percutaneous CT-guided radiofrequency ablation in spinal osteoid osteoma treatment. Acta Chir Orthop Traumatol Cech 74, 401–405 (2007)

    CAS  PubMed  Google Scholar 

  10. Barwick, K.W., Huvos, A.G., Smith, J.: Primary osteogenic sarcoma of the vertebral column: a clinicopathologic correlation of ten patients. Cancer 46, 595–604 (1980)

    Article  CAS  PubMed  Google Scholar 

  11. Benes 3rd, V., Barsa, P., Benes Jr., V., et al.: Prognostic factors in intramedullary astrocytomas: a literature review. Eur Spine J 18, 1397–1422 (2009)

    Article  PubMed  Google Scholar 

  12. Bertram, C., Madert, J., Eggers, C.: Eosinophilic granuloma of the cervical spine. Spine (Phila Pa 1976) 27, 1408–1413 (2002)

    Google Scholar 

  13. Blaylock, R.L., Kempe, L.G.: Chondrosarcoma of the cervical spine. Case report. J Neurosurg 44, 500–503 (1976)

    Article  CAS  PubMed  Google Scholar 

  14. Bohlman, H.H., Sachs, B.L., Carter, J.R., et al.: Primary neoplasms of the cervical spine. Diagnosis and treatment of twenty-three patients. J Bone Joint Surg Am 68, 483–494 (1986)

    CAS  PubMed  Google Scholar 

  15. Boriani, S., Bandiera, S., Biagini, R., et al.: Chordoma of the mobile spine: fifty years of experience. Spine (Phila Pa 1976) 31, 493–503 (2006)

    Google Scholar 

  16. Boriani, S., Biagini, R., De Iure, F., et al.: Primary bone tumors of the spine: a survey of the evaluation and treatment at the Istituto Ortopedico Rizzoli. Orthopedics 18, 993–1000 (1995)

    CAS  PubMed  Google Scholar 

  17. Boriani, S., Biagini, R., De Iure, F., et al.: En bloc resections of bone tumors of the thoracolumbar spine. A preliminary report on 29 patients. Spine (Phila Pa 1976) 21, 1927–1931 (1996)

    CAS  Google Scholar 

  18. Boriani, S., Capanna, R., Donati, D., et al.: Osteoblastoma of the spine. Clin Orthop Relat Res 278, 37–45 (1992)

    PubMed  Google Scholar 

  19. Boriani, S., De Iure, F., Campanacci, L., et al.: Aneurysmal bone cyst of the mobile spine: report on 41 cases. Spine (Phila Pa 1976) 26, 27–35 (2001)

    CAS  Google Scholar 

  20. Boriani, S., Nandiera, S., Weinstein, J.N.: Primary malignant tumors of the cervical spine. In: Clark, C.R., Benzel, E.C., Currier, B.L., et al. (eds.) The cervical spine, vol. 4, pp. 840–857. Lippincott, Philadelphia (2004)

    Google Scholar 

  21. Boriani, S., Weinstein, J.N., Biagini, R.: ) Primary bone tumors of the spine. Terminology and surgical staging. Spine (Phila Pa 1976) 22, 1036–1044 (1997)

    CAS  Google Scholar 

  22. Brada, M., Pijls-Johannesma, M., De Ruysscher, D.: Proton therapy in clinical practice: current clinical evidence. J Clin Oncol 25, 965–970 (2007)

    Article  PubMed  Google Scholar 

  23. Brihaye, J., Ectors, P., Lemort, M., et al.: The management of spinal epidural metastases. Adv Tech Stand Neurosurg 16, 121–176 (1988)

    CAS  PubMed  Google Scholar 

  24. Brotchi, J., Dewitte, O., Levivier, M., et al.: A survey of 65 tumors within the spinal cord: surgical results and the importance of preoperative magnetic resonance imaging. Neurosurgery 29, 651–657 (1991)

    Article  CAS  PubMed  Google Scholar 

  25. Bruneau, M., Polivka, M., Cornelius, J.F., et al.: Progression of an osteoid osteoma to an osteoblastoma. Case report. J Neurosurg Spine 3, 238–241 (2005)

    Article  PubMed  Google Scholar 

  26. Burn, S.C., Ansorge, O., Zeller, R., et al.: Management of osteoblastoma and osteoid osteoma of the spine in childhood. J Neurosurg Pediatr 4, 434–438 (2009)

    Article  PubMed  Google Scholar 

  27. Camins, M.B., Duncan, A.W., Smith, J., et al.: Chondrosarcoma of the spine. Spine (Phila Pa 1976) 3, 202–209 (1978)

    CAS  Google Scholar 

  28. Cantwell, C.P., O’Byrne, J., Eustace, S.: Radiofrequency ablation of osteoid osteoma with cooled probes and impedance-control energy delivery. AJR Am J Roentgenol 186, S244–S248 (2006)

    Article  PubMed  Google Scholar 

  29. Cantwell, C.P., Obyrne, J., Eustace, S.: Current trends in treatment of osteoid osteoma with an emphasis on radiofrequency ablation. Eur Radiol 14, 607–617 (2004)

    Article  PubMed  Google Scholar 

  30. Capanna, R., Albisinni, U., Picci, P., et al.: Aneurysmal bone cyst of the spine. J Bone Joint Surg Am 67, 527–531 (1985)

    CAS  PubMed  Google Scholar 

  31. Caudell, J.J., Ballo, M.T., Zagars, G.K., et al.: Radiotherapy in the management of giant cell tumor of bone. Int J Radiat Oncol Biol Phys 57, 158–165 (2003)

    Article  PubMed  Google Scholar 

  32. Chabot, M., Herkowitz, H.N.: Spine tumors: Patient evaluation. In: Weisel, S. (ed.) Seminars in spine surgery, vol. 7, pp. 260–268. Saunders, Philadelphia (1995)

    Google Scholar 

  33. Chakravarti, A., Spiro, I.J., Hug, E.B., et al.: Megavoltage radiation therapy for axial and inoperable giant-cell tumor of bone. J Bone Joint Surg Am 81, 1566–1573 (1999)

    CAS  PubMed  Google Scholar 

  34. Chan, P., Boriani, S., Fourney, D.R., et al.: An assessment of the reliability of the Enneking and Weinstein-Boriani-Biagini classifications for staging of primary spinal tumors by the Spine Oncology Study Group. Spine (Phila Pa 1976) 34, 384–391 (2009)

    Google Scholar 

  35. Choi, D., Melcher, R., Harms, J., et al.: Outcome of 132 operations in 97 patients with chordomas of the craniocervical junction and upper cervical spine. Neurosurgery 66, 59–65 (2010). discussion 65

    Article  PubMed  Google Scholar 

  36. Cohen, Z.R., Fourney, D.R., Marco, R.A., et al.: Total cervical spondylectomy for primary osteogenic sarcoma. Case report and description of operative technique. J Neurosurg 97, 386–392 (2002)

    PubMed  Google Scholar 

  37. Constans, J.P., de Divitiis, E., Donzelli, R., et al.: Spinal metastases with neurological manifestations. Review of 600 cases. J Neurosurg 59, 111–118 (1983)

    Article  CAS  PubMed  Google Scholar 

  38. Dahlin, D.C., Cupps, R.E., Johnson Jr., E.W.: Giant-cell tumor: a study of 195 cases. Cancer 25, 1061–1070 (1970)

    Article  CAS  PubMed  Google Scholar 

  39. Dahlin, D.C., McLeod, R.A.: Aneurysmal bone cyst and other nonneoplastic conditions. Skeletal Radiol 8, 243–250 (1982)

    Article  CAS  PubMed  Google Scholar 

  40. de Kleuver, M., van der Heul, R.O., Veraart, B.E.: Aneurysmal bone cyst of the spine: 31 cases and the importance of the surgical approach. J Pediatr Orthop B 7, 286–292 (1998)

    PubMed  Google Scholar 

  41. Di Lorenzo, N., Delfini, R., Ciappetta, P., et al.: Primary tumors of the cervical spine: surgical experience with 38 cases. Surg Neurol 38, 12–18 (1992)

    Article  PubMed  Google Scholar 

  42. Dominguez, C.J., Martin-Ferrer, S., Rimbau, J., et al.: Upper cervical chondrosarcoma. Neurocirugia (Astur) 16, 261–265 (2005). discussion 265

    CAS  Google Scholar 

  43. Dreghorn, C.R., Newman, R.J., Hardy, G.J., et al.: Primary tumors of the axial skeleton. Experience of the Leeds Regional Bone Tumor Registry. Spine (Phila Pa 1976) 15, 137–140 (1990)

    CAS  Google Scholar 

  44. Enneking, W.F.: A system of staging musculoskeletal neoplasms. Clin Orthop Relat Res 204, 9–24 (1986)

    PubMed  Google Scholar 

  45. Enneking, W.F., Spanier, S.S., Goodman, M.A.: A system for the surgical staging of musculoskeletal sarcoma. Clin Orthop Relat Res 153, 106–120 (1980)

    PubMed  Google Scholar 

  46. Epstein, F.J., Farmer, J.P., Freed, D.: Adult intramedullary spinal cord ependymomas: the result of surgery in 38 patients. J Neurosurg 79, 204–209 (1993)

    Article  CAS  PubMed  Google Scholar 

  47. Feigenberg, S.J., Marcus Jr., R.B., Zlotecki, R.A., et al.: Megavoltage radiotherapy for aneurysmal bone cysts. Int J Radiat Oncol Biol Phys 49, 1243–1247 (2001)

    Article  CAS  PubMed  Google Scholar 

  48. Fidler, M.W.: Surgical treatment of giant cell tumours of the thoracic and lumbar spine: report of nine patients. Eur Spine J 10, 69–77 (2001)

    Article  CAS  PubMed  Google Scholar 

  49. Fisher, C.G., Keynan, O., Boyd, M.C., et al.: The surgical management of primary tumors of the spine: initial results of an ongoing prospective cohort study. Spine (Phila Pa 1976) 30, 1899–1908 (2005)

    Google Scholar 

  50. Fourney, D.R., Rhines, L.D., Hentschel, S.J., et al.: En bloc resection of primary sacral tumors: classification of surgical approaches and outcome. J Neurosurg Spine 3, 111–122 (2005)

    Article  PubMed  Google Scholar 

  51. Frank, E., Chamberland, D., Ragel, B.: A proposed technique for intraoperative measurement of cervical spine stiffness. Neurosurgery 39, 147–150 (1996)

    Article  CAS  PubMed  Google Scholar 

  52. Fujita, T., Kawahara, N., Matsumoto, T., et al.: Chordoma in the cervical spine managed with en bloc excision. Spine (Phila Pa 1976) 24, 1848–1851 (1999)

    CAS  Google Scholar 

  53. Gabrielsen, T.O., Seeger, J.F.: Vertebral angiography in the diagnosis of intraspinal masses in upper cervical region. Neuroradiology 5, 7–12 (1973)

    Article  CAS  PubMed  Google Scholar 

  54. Gebes, S., Winking, M.: Plasmacytoma involving the atlas and axis. Neurochirurgia (Stuttg) 32, 187–188 (1989)

    CAS  Google Scholar 

  55. George, B., Lot, G., Boissonnet, H.: Meningioma of the foramen magnum: a series of 40 cases. Surg Neurol 47, 371–379 (1997)

    Article  CAS  PubMed  Google Scholar 

  56. George, B., Lot, G., Velut, S., et al.: French language Society of Neurosurgery. 44th Annual Congress. Brussels, 8-12 June 1993. Tumors of the foramen magnum. Neurochirurgie 39(1), 1–89 (1993)

    PubMed  Google Scholar 

  57. Guidetti, B., Mercuri, S., Vagnozzi, R.: Long-term results of the surgical treatment of 129 intramedullary spinal gliomas. J Neurosurg 54, 323–330 (1981)

    Article  CAS  PubMed  Google Scholar 

  58. Harrington, K.D.: The use of methylmethacrylate for vertebral-body replacement and anterior stabilization of pathological fracture-dislocations of the spine due to metastatic malignant disease. J Bone Joint Surg Am 63, 36–46 (1981)

    CAS  PubMed  Google Scholar 

  59. Harrop, J.S., Schmidt, M.H., Boriani, S., et al.: Aggressive “benign” primary spine neoplasms: osteoblastoma, aneurysmal bone cyst, and giant cell tumor. Spine (Phila Pa 1976) 34, 39–47 (2009)

    Google Scholar 

  60. Hastings, D.E., Macnab, I., Lawson, V.: Neoplasms of the atlas and axis. Can J Surg 11, 290–296 (1968)

    CAS  PubMed  Google Scholar 

  61. Hay, M.C., Paterson, D., Taylor, T.K.: Aneurysmal bone cysts of the spine. J Bone Joint Surg Br 60, 406–411 (1978)

    PubMed  Google Scholar 

  62. Hosalkar, H.S., Jones, K.J., King, J.J., et al.: Serial arterial embolization for large sacral giant-cell tumors: mid- to long-term results. Spine (Phila Pa 1976) 32, 1107–1115 (2007)

    Google Scholar 

  63. Hug, E.B., Fitzek, M.M., Liebsch, N.J., et al.: Locally challenging osteo- and chondrogenic tumors of the axial skeleton: results of combined proton and photon radiation therapy using three-dimensional treatment planning. Int J Radiat Oncol Biol Phys 31, 467–476 (1995)

    Article  CAS  PubMed  Google Scholar 

  64. Hyun, S.J., Rhim, S.C., Riew, K.D.: A combined posterior, lateral, and anterior approach to ventrolaterally situated chordoma of the upper cervical spine. Surg Neurol 72, 409–413 (2009). discussion 413

    Article  PubMed  Google Scholar 

  65. Jackson, R.P.: Recurrent osteoblastoma: a review. Clin Orthop Relat Res 131, 229–233 (1978)

    PubMed  Google Scholar 

  66. Jackson, R.P., Reckling, F.W., Mants, F.A.: Osteoid osteoma and osteoblastoma. Similar histologic lesions with different natural histories. Clin Orthop Relat Res 128, 303–313 (1977)

    PubMed  Google Scholar 

  67. Jaffe, H., Lichtenstein, I.: Solitary unicameral bone cyst with emphasis on the roentgen picture, the pathologic appearance and the pathogenesis. Arch Surg 44, 1004–1025 (1942)

    Google Scholar 

  68. Kaibara, T., Hurlbert, R.J., Sutherland, G.R.: Transoral resection of axial lesions augmented by intraoperative magnetic resonance imaging. Report of three cases. J Neurosurg 95, 239–242 (2001)

    CAS  PubMed  Google Scholar 

  69. Kaiser, T.E., Pritchard, D.J., Unni, K.K.: Clinicopathologic study of sacrococcygeal chordoma. Cancer 53, 2574–2578 (1984)

    Article  CAS  PubMed  Google Scholar 

  70. Khan, D.C., Malhotra, S., Stevens, R.E., et al.: Radiotherapy for the treatment of giant cell tumor of the spine: a report of six cases and review of the literature. Cancer Invest 17, 110–113 (1999)

    CAS  PubMed  Google Scholar 

  71. Kingdom, T.T., Nockels, R.P., Kaplan, M.J.: Transoral-transpharyngeal approach to the craniocervical junction. Otolaryngol Head Neck Surg 113, 393–400 (1995)

    Article  CAS  PubMed  Google Scholar 

  72. Konya, D., Ozgen, S., Gercek, A., et al.: Transmandibular approach for upper cervical pathologies: report of 2 cases and review of the literature. Turk Neurosurg 18, 271–275 (2008)

    PubMed  Google Scholar 

  73. Kostuik, J., Weinstein, J.N.: Differential diagnosis and surgical treatment of metastatic spine tumors. In: Frymoyer, J. (ed.) The adult spine: principles and practice, pp. 861–888. Raven, New York (1991)

    Google Scholar 

  74. Laus, M., Albisinni, U., Alfonso, C., et al.: Osteoid osteoma of the cervical spine: surgical treatment or percutaneous radiofrequency coagulation? Eur Spine J 16, 2078–2082 (2007)

    Article  CAS  PubMed  Google Scholar 

  75. Lee, F.Y., Mankin, H.J., Fondren, G., et al.: Chondrosarcoma of bone: an assessment of outcome. J Bone Joint Surg Am 81, 326–338 (1999)

    Article  CAS  PubMed  Google Scholar 

  76. Levine, A.M., Boriani, S.: Benign tumors of cervical spine. In: Clark, C.R., Benzel, E.C., Currier, B.L., et al. (eds.) The cervical spine, vol. 4, pp. 816–839. Lippincott, Philadelphia (2005)

    Google Scholar 

  77. Levine, A.M., Boriani, S., Donati, D., et al.: Benign tumors of the cervical spine. Spine (Phila Pa 1976) 17, 399–406 (1992)

    Google Scholar 

  78. Lichtenstein, L., Jeffe, H.L.: Eosinophilic granuloma of bone: with report of a case. Am J Pathol 16(595–604), 593 (1940)

    Google Scholar 

  79. Lichtenstein, L., Sawyer, W.R.: Benign osteoblastoma. Further observations and report of twenty additional cases. J Bone Joint Surg Am 46, 755–765 (1964)

    CAS  PubMed  Google Scholar 

  80. Lis, E., Bilsky, M.H., Pisinski, L., et al.: Percutaneous CT-guided biopsy of osseous lesion of the spine in patients with known or suspected malignancy. AJNR Am J Neuroradiol 25, 1583–1588 (2004)

    PubMed  Google Scholar 

  81. Lucas, D.R., Unni, K.K., McLeod, R.A., et al.: Osteoblastoma: clinicopathologic study of 306 cases. Hum Pathol 25, 117–134 (1994)

    Article  CAS  PubMed  Google Scholar 

  82. Marmor, E., Rhines, L.D., Weinberg, J.S., et al.: Total en bloc lumbar spondylectomy. Case report. J Neurosurg 95, 264–269 (2001)

    CAS  PubMed  Google Scholar 

  83. Marsh, B.W., Bonfiglio, M., Brady, L.P., et al.: Benign osteoblastoma: range of manifestations. J Bone Joint Surg Am 57, 1–9 (1975)

    CAS  PubMed  Google Scholar 

  84. McCormick, P.C., Torres, R., Post, K.D., et al.: Intramedullary ependymoma of the spinal cord. J Neurosurg 72, 523–532 (1990)

    Article  CAS  PubMed  Google Scholar 

  85. McLain, R.F., Weinstein, J.N.: Solitary plasmacytomas of the spine: a review of 84 cases. J Spinal Disord 2, 69–74 (1989)

    Article  CAS  PubMed  Google Scholar 

  86. Munzenrider, J.E., Liebsch, N.J.: Proton therapy for tumors of the skull base. Strahlenther Onkol 175(Suppl 2), 57–63 (1999)

    Article  PubMed  Google Scholar 

  87. Murphey, M.D., Andrews, C.L., Flemming, D.J., et al.: From the archives of the AFIP. Primary tumors of the spine: radiologic pathologic correlation. Radiographics 16, 1131–1158 (1996)

    CAS  PubMed  Google Scholar 

  88. Murphy, W.A., Strecker, E.B., Schoenecker, P.L.: Transcatheter embolisation therapy of an ischial aneurysmal bone cyst. J Bone Joint Surg Br 64, 166–168 (1982)

    CAS  PubMed  Google Scholar 

  89. Nagashima, H., Nishi, T., Yamane, K., et al.: Case report: osteoid osteoma of the C2 pedicle: surgical technique using a navigation system. Clin Orthop Relat Res 468, 283–288 (2010)

    Article  PubMed  Google Scholar 

  90. Nesbit Jr., M.E., Gehan, E.A., Burgert Jr., E.O., et al.: Multimodal therapy for the management of primary, nonmetastatic Ewing’s sarcoma of bone: a long-term follow-up of the First Intergroup study. J Clin Oncol 8, 1664–1674 (1990)

    PubMed  Google Scholar 

  91. Neumann, D., Dorn, U.: Osteoid osteoma of the dens axis. Eur Spine J 16(Suppl 3), 271–274 (2007)

    Article  PubMed  Google Scholar 

  92. Noel, G., Feuvret, L., Calugaru, V., et al.: Chordomas of the base of the skull and upper cervical spine. One hundred patients irradiated by a 3D conformal technique combining photon and proton beams. Acta Oncol 44, 700–708 (2005)

    Article  PubMed  Google Scholar 

  93. Nyholm, K.: Eosinophilic xanthomatous granulomatosis and Letterer-Siwe’s disease. Acta Pathol Microbiol Scand Suppl 216, 211+ (1971)

    Google Scholar 

  94. Ono, K., Ebara, S., Fuji, T., et al.: Myelopathy hand. New clinical signs of cervical cord damage. J Bone Joint Surg Br 69, 215–219 (1987)

    CAS  PubMed  Google Scholar 

  95. Otani, S., Ehrlich, J.C.: Solitary granuloma of bone: Simulating primary neoplasm. Am J Pathol 16(479–490), 477 (1940)

    Google Scholar 

  96. Peraud, A., Drake, J.M., Armstrong, D., et al.: Fatal ethibloc embolization of vertebrobasilar system following percutaneous injection into aneurysmal bone cyst of the second cervical vertebra. AJNR Am J Neuroradiol 25, 1116–1120 (2004)

    CAS  PubMed  Google Scholar 

  97. Phillips, E., Levine, A.M.: Metastatic lesions of the upper cervical spine. Spine (Phila Pa 1976) 14, 1071–1077 (1989)

    CAS  Google Scholar 

  98. Pierot, L., Boulin, A.: Percutaneous biopsy of the thoracic and lumbar spine: transpedicular approach under fluoroscopic guidance. AJNR Am J Neuroradiol 20, 23–25 (1999)

    CAS  PubMed  Google Scholar 

  99. Prasad, V.S., Raju, B.S., Sundaram, C.: Plasmacytoma of dens as a cause of atlanto-axial instability. Spinal Cord 36, 661–663 (1998)

    Article  CAS  PubMed  Google Scholar 

  100. Rao, S., Badani, K., Schildhauer, T., et al.: Metastatic malignancy of the cervical spine. A nonoperative history. Spine (Phila Pa 1976) 17, 407–412 (1992)

    Google Scholar 

  101. Raskas, D.S., Graziano, G.P., Herzenberg, J.E., et al.: Osteoid osteoma and osteoblastoma of the spine. J Spinal Disord 5, 204–211 (1992)

    Article  CAS  PubMed  Google Scholar 

  102. Raycroft, J.F., Hockman, R.P., Southwick, W.O.: Metastatic tumors involving the cervical vertebrae: surgical palliation. J Bone Joint Surg Am 60, 763–768 (1978)

    CAS  PubMed  Google Scholar 

  103. Rhines, L.D., Fourney, D.R., Siadati, A., et al.: En bloc resection of multilevel cervical chordoma with C-2 involvement. Case report and description of operative technique. J Neurosurg Spine 2, 199–205 (2005)

    Article  PubMed  Google Scholar 

  104. Rich, T.A., Schiller, A., Suit, H.D., et al.: Clinical and pathologic review of 48 cases of chordoma. Cancer 56, 182–187 (1985)

    Article  CAS  PubMed  Google Scholar 

  105. Robins, S.L.: Pathology, 3rd edn, pp. 1649–1650. Saunders, Philadelphia (1967)

    Google Scholar 

  106. Rose, E.F., Fekete, A.: Odontoid osteochondroma causing sudden death. Report of a case and review of the literature. Am J Clin Pathol 42, 606–609 (1964)

    CAS  PubMed  Google Scholar 

  107. Samii, M., Klekamp, J., Carvalho, G.: Surgical results for meningiomas of the craniocervical junction. Neurosurgery 39, 1086–1094 (1996). discussion 1094–1085

    Article  CAS  PubMed  Google Scholar 

  108. Sar, C., Eralp, L.: Transoral resection and reconstruction for primary osteogenic sarcoma of the second cervical vertebra. Spine (Phila Pa 1976) 26, 1936–1941 (2001)

    CAS  Google Scholar 

  109. Schellinger, K.A., Propp, J.M., Villano, J.L., et al.: Descriptive epidemiology of primary spinal cord tumors. J Neurooncol 87, 173–179 (2008)

    Article  PubMed  Google Scholar 

  110. Sciubba, D.M., Okuno, S.H., Dekutoski, M.B., et al.: Ewing and osteogenic sarcoma: evidence for multidisciplinary management. Spine (Phila Pa 1976) 34, 58–68 (2009)

    Google Scholar 

  111. Shives, T.C., Dahlin, D.C., Sim, F.H., et al.: Osteosarcoma of the spine. J Bone Joint Surg Am 68, 660–668 (1986)

    CAS  PubMed  Google Scholar 

  112. Shives, T.C., McLeod, R.A., Unni, K.K., et al.: Chondrosarcoma of the spine. J Bone Joint Surg Am 71, 1158–1165 (1989)

    CAS  PubMed  Google Scholar 

  113. Simmons, E.D., Zheng, Y.: Vertebral tumors: surgical versus nonsurgical treatment. Clin Orthop Relat Res 443, 233–247 (2006)

    Article  PubMed  Google Scholar 

  114. Suchomel, P., Buchvald, P., Barsa, P., et al.: Single-stage total C-2 intralesional spondylectomy for chordoma with three-column reconstruction. Technical note. J Neurosurg Spine 6, 611–618 (2007)

    Article  PubMed  Google Scholar 

  115. Suit, H.D., Goitein, M., Munzenrider, J., et al.: Definitive radiation therapy for chordoma and chondrosarcoma of base of skull and cervical spine. J Neurosurg 56, 377–385 (1982)

    Article  CAS  PubMed  Google Scholar 

  116. Sundaresan, N., Boriani, S., Okuno, S.: State of the art management in spine oncology: a worldwide perspective on its evolution, current state, and future. Spine (Phila Pa 1976) 34, 7–20 (2009)

    Google Scholar 

  117. Sundaresan, N., Galicich, J.H., Chu, F.C., et al.: Spinal chordomas. J Neurosurg 50, 312–319 (1979)

    Article  CAS  PubMed  Google Scholar 

  118. Suttner, N.J., Chandy, K.J., Kellerman, A.J.: Osteoid osteomas of the body of the cervical spine. Case report and review of the literature. Br J Neurosurg 16, 69–71 (2002)

    Article  CAS  PubMed  Google Scholar 

  119. Talac, R., Yaszemski, M.J., Currier, B.L., et al.: Relationship between surgical margins and local recurrence in sarcomas of the spine. Clin Orthop Relat Res 397, 127–132 (2002)

    Article  PubMed  Google Scholar 

  120. Thiry, S., Steenebruggen, A., Hotermans, J.M., et al.: Complete destruction of the body of the axis by a myeloplasmacytoma. Resection by the transoral route and reconstruction of the vertebral body by a bone graft. Presentation of a case 2 years after intervention. Neurochirurgie 14, 799–808 (1968)

    CAS  PubMed  Google Scholar 

  121. Thomson, A.D., Turner-Warwick, R.T.: Skeletal sarcomata and giant-cell tumour. J Bone Joint Surg Br 37-, 266–303 (1955)

    PubMed  Google Scholar 

  122. Tokuhashi, Y., Matsuzaki, H., Oda, H., et al.: A revised scoring system for preoperative evaluation of metastatic spine tumor prognosis. Spine (Phila Pa 1976) 30, 2186–2191 (2005)

    Google Scholar 

  123. Tokuhashi, Y., Matsuzaki, H., Toriyama, S., et al.: Scoring system for the preoperative evaluation of metastatic spine tumor prognosis. Spine (Phila Pa 1976) 15, 1110–1113 (1990)

    CAS  Google Scholar 

  124. Tomita, K., Kawahara, N., Baba, H., et al.: Total en bloc spondylectomy. A new surgical technique for primary malignant vertebral tumors. Spine (Phila Pa 1976) 22, 324–333 (1997)

    CAS  Google Scholar 

  125. Tomita, K., Kawahara, N., Kobayashi, T., et al.: Surgical strategy for spinal metastases. Spine (Phila Pa 1976) 26, 298–306 (2001)

    CAS  Google Scholar 

  126. Torma, T.: Malignant tumours of the spine and the spinal extradural space; a study based on 250 histologically verified cases. Acta Chir Scand Suppl 225, 1–176 (1957)

    CAS  PubMed  Google Scholar 

  127. Verbiest, H.: Giant-cell tumours and aneurysmal bone cysts of the spine. With special reference to the problems related to the removal of a vertebral body. J Bone Joint Surg Br 47, 699–713 (1965)

    CAS  PubMed  Google Scholar 

  128. Vergel De Dios, A.M., Bond, J.R., Shives, T.C., et al.: Aneurysmal bone cyst. A clinicopathologic study of 238 cases. Cancer 69, 2921–2931 (1992)

    Article  CAS  PubMed  Google Scholar 

  129. Weber, K.L.: Current concepts in the treatment of Ewing’s sarcoma. Expert Rev Anticancer Ther 2, 687–694 (2002)

    Article  PubMed  Google Scholar 

  130. Weiner, H.L., Freed, D., Woo, H., et al.: Intra-axial tumors of the cervicomedullary junction: surgical results and long-term outcome. Pediatr Neurosurg 27, 12–18 (1997)

    Article  CAS  PubMed  Google Scholar 

  131. Weinstein, J.M.: Spine neoplasms. In: Weinstein, J.M. (ed.) The pediatric spine, pp. 887–916. Raven, New York (1994)

    Google Scholar 

  132. Wilner, D.: Radiology of bone tumors and allied disorders, vol. 2. Saunders, Philadelphia (1982)

    Google Scholar 

  133. Yamazaki, T., McLoughlin, G.S., Patel, S., et al.: Feasibility and safety of en bloc resection for primary spine tumors: a systematic review by the Spine Oncology Study Group. Spine (Phila Pa 1976) 34, 31–38 (2009)

    Google Scholar 

  134. Zileli, M., Cagli, S., Basdemir, G., et al.: Osteoid osteomas and osteoblastomas of the spine. Neurosurg Focus 15, E5 (2003)

    PubMed  Google Scholar 

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  1. Department of Neurosurgery, Neurocenter, Regional Hospital Liberec, Husova St. 10, 46063, Liberec, Czech Republic

    P. Suchomel, V. Benes & M. Kaiser

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  2. V. Benes
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Suchomel, P., Benes, V., Kaiser, M. (2011). Tumors. In: Reconstruction of Upper Cervical Spine and Craniovertebral Junction. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-13158-5_19

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