Zusammenfassung
Anämien in der Schwangerschaft und im Wochenbett sind in Abhängigkeit der Schwere und der möglichen zusätzlichen Komplikationen mit einer erhöhten maternalen und fetalen Morbidität und Mortalität verbunden. Sie gehören zu den häufigsten Risikofaktoren im Bereich der Geburtshilfe und Perinatalmedizin.
Literatur
ACOG (1996) Hemoglobinopathies in pregnancy. ACOG Tech Bull 1–9
Al A, Unlubilgin E, Kandemir O, Yalvac S, Cakir L, Haberal A (2005) Intavenous verus oral iron for treatment of anemia in pregnancy. Obstet Gynecol 106: 1335–1340
al-Momen AK, al-Meshari A, al-Nuaim L, Saddique A, Abotalib Z, Khashogji T, Abbas M (1996) Intravenous iron sucrose complex in the treatment of iron deficiency anemia during pregnancy. Eur J Obstet Gynecol Reprod Biol 69 (2): 121–124
Bayoumeu F, Vial F, Zaccabri A, Agullès O, Laxenaire MC (2002) Iron therapy in iron deficiency anemia in pregnancy: intravenous route versus oral route. Am J Obstet Gynecol 186: 518–522
Beguin Y, Lipcsei G, Thoumsin H, Fillet G (1991) Blunted erythropoietin production and decreased erythropoiesis in early pregnancy. Blood 78: 89–91
Braga J, Marques R, Branco A, Jorge C (1996) Maternal and perinatal implications of the use of human recombinant erythropoietin. Acta Obstet Gynecol Scand 75: 449–453
Breymann C, Huch R (2008) Anemia in Pregnancy and the Puerperium. UNI-MED Science, 3rd edition. ISBN 978-3-8374-1022–1228
Breymann C, Major A., Huch R., Huch A (1995) Recombinant human EPO and parenteral iron in the treatment of pregnancy anemia: a pilot study. Feto Maternal Hematology Research Group University of Zurich, Zurich, Switzerland. J Perinat Med 23: 89–98
Breymann C, Zimmermann R, Huch R, Huch A (1996) Use of recombinant erythropoietin in combination with parenteral iron in the treatment of postpartum anaemia. Eur J Clin Invest 26: 123–130
Breymann C, Visca E, Huch R, Huch A (2001) Efficacy and safety of intravenously administered iron sucrose with and without adjuvant recombinant human erythropoietin for the treatment of resistant iron-deficiency anemia during pregnancy. Am J Obstet Gynecol 184: 662–667
Breymann C, Zimmermann R, Huch R, Huch A (1996) Use of recombinant erythropoietin in combination with parenteral iron in the treatment of postpartum anaemia. Eur J Clin Invest 26: 123–130
Breymann C, Visca E, Huch R, Huch A (2001) Efficacy and safety of intravenously administered iron sucrose with and without adjuvant recombinant human erythropoietin for the treatment of resistant iron-deficiency anemia during pregnancy. Am J Obstet Gynecol 184: 662–667
Breymann C et al. (2007) [www.sggg.ch/D/intern/expertenbriefe/22- D-Diagnostik-und-Therapie-der-Anaemie-in-der-Schwangerschaft- und-postpartal.pdf]
Breymann C, Gliga F, Bejenariu C, Strizhova N (2008) Comparative efficacy and safety of intravenous ferric carboxymaltose in the treatment of postpartum iron deficiency anemia. Int J Gynaecol Obstet 101:67–73
Bridges K (1990) Iron imbalance during pregnancy. In: Bern M, Frigoletto F (eds) Hematologic disorders in maternal-fetal medicine.Wiley & Liss, New York, pp 113–128
CDC (1989) CDC Criteria for anemia in children and childbearingaged women. Morbid Mortal Weekly Rep 38: 400–404
Charache S (1990) Hemoglobinopathies. In: Bern M, Frigoletto F (eds) Hematologic disorders in maternal-fetal medicine. Wiley & Liss, New York, pp 171–181
Cook J, Finch C, Smith N (1976) Evaluation of the iron status of a population. Blood 48: 449–455
Dee D, Sharma A, Cogswell M, Grummer-Strawn L, Fein S, Scanlon K (2008) Sources of supplemental iron among breastfed infants during the first year of life. Pediatrics 122: S 98–104
Dodd J, Dare M, Middleton P (2004) Treatment for women with postpartum iron deficiency anemia. Cochrane Database Syst Rev 004222
Ekeroma A, Ansari A, Stirrat G (1997) Blood transfusion in obstetrics and gynaecology. Br J Obstet Gynaecol 104: 278–284
Fuchs D, Zangerle R, Dworzak E et al. (1993) Association between immune activation, changes of iron metabolism and anaemia in patients with HIV infection. Eur J Haematol 50: 90–94
Gibson R (1990a) Assessement of iron staus. In: Gibson R Principles of nutritional assessement. Oxford Univ Press, pp 349–376
Gibson R (1990b) Assessement of the status of folate and vitamin B- 12. In: Gibson R Principles of nutritional assessment. Oxford Univ Press, pp 461–486
Goepel E, Ulmer H, Neth R (1988) Premature labor contractions and the value of serumferritin during pregnancy. Gynecol Obstet Invest 26: 265–273
Guidozzi F, Patel R, McPhail A (1995) A prospective study of iron status in white and black pregnant women in an urban hospital. SAMJ 85: 171–173
Hallberg L (1994) Prevention of iron deficiency. Baillieres Clin Haematol 7: 805–814
Harris E (1992) New insights into placental iron transport. Nutr Rev 50: 329–331
Hemminki E, Meriläinen J (1995) Long-term follow-up of mothers and their infants in a randomized trial on iron prophylaxis during pregnancy. Am J Obstet Gynecol 173: 205–209
Hollan S, Johansen K (1993) Adequate iron stores and the »nil nocere« principle. Haematologia 25: 69–84
Huch R, Breymann C (2005) Anämie in Schwangerschaft und Wochenbett, 1. Aufl. UNI-MED Science, Bremen
Huch R, Huch A (1994) Erythropoietin in obstetrics. Hematol Oncol Clin North Am 8: 1021–1040
Kaufer M, Casanueva E (1990) Relation of prepregnancy serum ferritin levels to hemoglobin levels throughout pregnancy. Eur J Clin Nutr 44: 709–715
Krafft A, Bencaiova B, Breymann C (2009) Selective use of recombinant human erythropoietin in pregnant patients with severe anemia or nonresponsive to iron sucrose alone. Fetal Diagn Ther 25: 239–245
Krafft A, Frischknecht H, Breymann C. (2004a) Haemoglobinopathy in pregnancy: diagnosis and treatment. Curr Med Chem 11: 2903–2909
Krafft A, Perewusnyk G, Hänseler E, Quack K, Breymann C (2004b) The effect of postpartum oral iron supplementation on haematologic parameters in iron deficient women without anaemia. BJOG 111: 1–6
Krapels I, van Rooij I, Ocké M, West C, van der Horts C, Steegers-Theunissen R (2004) maternal nutritional status and the risk for orofacial cleft offspring in humans. J Nutr 134: 3106–3113
Krawinkel M, Bethge M, Karib AO, Ahmet HM, Mirghani OA (1990) Maternal ferritin values and fetal iron stores. Acta Paediatr Scand 79/4: 467
Mahomed K, Hytten F (1991) Iron and folate supplementation in pregnancy. In: Chalmers I, Enkin M, Keirse M Effective care in pregnancy and childhood. Oxford Univ Press, pp 300–315
Malek A (2010) In vitro studies of ferric carboxymaltose on placental permeability using the dual perfusion model of human placenta. Arzneimittelforschung 60(69): 354–361
Mayhew TM, Charnock-Jones DS, Kaufmann P (2004) Aspects of human fetoplacental angiogenesis. Changes in complicated pregnancies. Placenta 25: 127–139
McCalla C (1994) Sickle cell disease in pregnacy. Postgrad Obstet Gynecol 14: 1–5
Milman N, Agger A, Nielsen O (1994) Iron status markers and serum erythropoietin in 120 mothers and newborn infants; effect of iron supplementation in normal pregnancy. Acta Obstet Gynecol Scand 73: 200–204
Mitchell E, Robinson E, Clark P, Becroft D, Glavisch N, Pattison N, Pryor J, Thompson J, Wild C (2004) Maternal nutritional risk factors for small gestational age babies in developed country: a case control study. Arch Dis Child Fetal Neonatal Ed 89: F431–435
Pena-Rosas JP, Viteri FE (2006) Effects of routine oral iron supplementation with or without folic acid for women during pregnancy Cochrane Database Syst Rev 3: 004736
Punnonen K, Irjala K, Rajamaki A (1997) Serum transferrin receptor and its ratio to serum ferritin in the diagnosis of iron deficiency. Blood 89: 1052–1057
Reveiz L, Gyte GM, Cuervo LG (2007) Treatments for. Iron-deficiency anaemia in pregnancy. Cochrane Database Syst Rev, Issue 1, 003094
Ronnenberg A, Wood R, Wang X, Xing H, Chen C, Chen D, Guang W, Huang A, Wang L, Xu X (2004) Preconception Hemoglobin and ferritin Concentrations are Associated with Pregnancy Outcome in a Prospective Cohort of Chinese Women. J Nutrit 134: 2586–2591
Rosenlöf K, Kivivuori S, Riska C, Teppo A, Slimes M (1995) Iron availability is transiently improved by intravenous iron medication in patients on chronic hemodialysis. Clin Nephrol 43: 249–255
Schaefer R, Schaefer L (1995) The hypochromic red cell: a new parameter for monitoring of iron supplementation during rhEPO therapy. J Perinat Med 23: 83–88
Seefried B (1995) Vergleichende Untersuchung von hämatologischen Parametern und des Eisenstoffwechsels von Müttern und Neugeborenen unter Anwendung der Retikulozytenflowzytometrie. Dissertation, Universitätsspital Zürich
Seid M, Derman R, Banach W, Goldberg C, Rogers R (2008) ferric carboxymaltose injection in the treatment of iron deficiency anemia: a randomized controlled clinical trial. Am J Obstet Gynecol 199: 435: e1–7
Spivak J (1995) Serum immunoreactive erythropoietin in health and disease. J Perinat Med 23: 13–17
USPSTF, US Preventive Services Task Force (1993) Routine iron supplementation during pregnancy. JAMA 15: 2846–2854
Van Wyck D, Martens M, Baker J, Mangione A (2007) Intravenous ferric carboxymaltose compared with oral iron in the treatment of postpartum anemia: a randomized controlled trial. Obstet Gynecol 110: 267–278
Wali A, Mushtaq A (2002) Efficacy, safety and compliance of intravenous iron sucrose and intramuscular iron sorbitol in iron deficiency anemia in pregnancy. J Pak Med Assoc 52: 392–395
Warth J (1990) Sickle cell disease. In: Bern M, Frigoletto F (eds) Hematologic disorders in maternal-fetal medicine. Wiley & Liss, New York, pp 183–197
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2011 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Breymann, C. (2011). Anämie. In: Schneider, H., Husslein, PW., Schneider, K. (eds) Die Geburtshilfe. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-12974-2_18
Download citation
DOI: https://doi.org/10.1007/978-3-642-12974-2_18
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-40181-7
Online ISBN: 978-3-642-12974-2
eBook Packages: Medicine (German Language)