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Optical Probes

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Small Animal Imaging

Abstract

The application of optical imaging technologies for drug discovery research and the development of novel preclinical animal models has expanded with tremendous vigor in the past few years. The fact that fluorescent dyes can be detected at low concentrations and nonionizing and harmless radiation is applied with rather low technical effort makes optical techniques attractive for routine use in the animal imaging laboratory. Novel imaging probes and contrast agents have been designed in a broad variety addressing the various requirements given by the disease problem at the preclinical animal imaging stage. Moreover, the industry has identified this field as a market from the side both the imaging equipment and the fluorescent probes applied as readily injectable contrast agents or reactive labels for bioconjugation chemistry.

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Author information

Authors and Affiliations

  1. mivenion GmbH, Robert-Koch-Platz 4, 10115, Berlin, Germany

    Kai Licha

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  1. Kai Licha
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Correspondence to Kai Licha .

Editor information

Editors and Affiliations

  1. Chair of Experimental Molecular Imaging, University of Aachen (RWTH), Pauwelsstraße 20, Aachen, 52074, Germany

    Fabian Kiessling

  2. Laboratory for Preclinical Imaging and Imaging Technology of the Werner Siemens-Foundation, Department of Radiology, Eberhard Karls University of Tübingen, Röntgenweg 13, Tübingen, 72076, Germany

    Bernd J. Pichler

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© 2011 Springer-Verlag Berlin Heidelberg

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Licha, K. (2011). Optical Probes. In: Kiessling, F., Pichler, B. (eds) Small Animal Imaging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-12945-2_21

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  • DOI: https://doi.org/10.1007/978-3-642-12945-2_21

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-12944-5

  • Online ISBN: 978-3-642-12945-2

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