Zusammenfassung
Der akute Blutverlust stellt seit jeher eines der schwierigsten Probleme in der Notfall- und operativen Medizin dar. Außer dem Volumenverlust ist auch der Verlust der einzelnen Blutkomponenten zu beachten, da das Blut den vielfältigen Anforderungen nur bei optimalem Zusammenwirken seiner Bestandteile gerecht werden kann. Neben dem Transport von Sauerstoff, Nährstoffen, Stoffwechselmetaboliten und Komponenten des körpereigenen Immunsystems nimmt das Blut auch eine zentrale Rolle bei der Steuerung der intrinsischen Gerinnung ein. Aus diesem Grund ist beim akuten Blutverlust nicht nur an den Volumenverlust und den Verlust an Sauerstofftransportkapazität zu denken, sondern auch an den Verlust gerinnungsaktiver Komponenten. Besonders in der Kombination mit anderen schweren systemischen Reaktionen wie beim Schock oder während einer Sepsis sind Gerinnungsstörungen keine Seltenheit. Ziel dieses Kapitels ist es, die gebräuchlichsten Richtgrößen zur Therapie von akuten Blutverlusten in der operativen Medizin unter Einbeziehung der von der Bundesärztekammer formulierten Leitlinien darzulegen.
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Scheeren, T., Hergert, S., Nöldge-Schomburg, G. (2010). Akuter Blutverlust in der operativen Medizin. In: Kiefel, V., Mueller-Eckhardt, C. (eds) Transfusionsmedizin und Immunhämatologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-12765-6_21
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