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Airborne Particulate Matter, Platinum Group Elements and Human Health

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Abstract

The platinum group elements (PGE), platinum (Pt), palladium (Pd) and rhodium (Rh), are emitted in small amounts in the exhaust of automobiles equipped with catalytic converters, which employ these metals as catalysts to convert nitrous oxide (NO x ), carbon monoxide (CO) and hydrocarbons (HCs) into more benign forms prior to their release. While catalytic converters have reduced these noxious emissions, the environmental concentrations of PGE concentrations have significantly increased over time due to their use. More recent studies on PGE in biologically relevant media such as airborne fine and ultrafine particulate matter (PM) indicate that exposures to these metals are indeed a human health concern. First, emitted PGE may be easily mobilised and solubilised by various compounds commonly present in the environment, thereby enhancing their bioavailability. Second, PGE may be transformed into more toxic species upon uptake by organisms. Third, PGE are also present in the fine fraction of aerosols that have been associated with increases in morbidity and mortality, especially in vulnerable populations such as children and the elderly. All these factors highlight the need to monitor environmental levels of PGE and continue research on their bioavailability, behaviour, and speciation and associated toxicity to enable us to better assess the risks they may pose to human health.

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References

  • Alsenz H, Zereini F, Wiseman C, Püttmann W (2009) Determination of palladium in airborne particulate matter using isotope dilution-quadrupole-inductively coupled plasma-mass spectrometry (ID-Q-ICP-MS) with helium as a collision gas after reductive co-precipitation with mercury. Anal Bioanal Chem 395:1919–1927

    Article  CAS  Google Scholar 

  • Alt F, Bambauer A, Hoppstock K, Mergler B, Tölg G (1993) Platinum traces in airborne particulate matter. Determination of whole content, particle size distribution and soluble platinum. Fresenius J Anal Chem 346:693–696

    Article  CAS  Google Scholar 

  • Artelt S, Kock H, König HP, Levsen K, Rosner G (1999) Engine dynamometer experiments: platinum emissions from differently aged three-way catalytic converters. Atmos Environ 33:3559–3567

    Article  CAS  Google Scholar 

  • Artelt S, Levsen K, König HP, Rosner G (2000) Engine test bench experiments to determine platinum emissions from three-way catalytic converters. In: Zereini F, Alt F (eds) Anthropogenic platinum group element emissions. Their impact on man and environment. Springer-Verlag, Berlin, pp 33–44

    Chapter  Google Scholar 

  • Barbante C, Veysseyre A, Ferrari C, Van de Velde K, Morel C, Capodoglio G, Cescon P, Scarponi G, Boutron C (2001) Greenland snow evidence of large scale atmospheric contamination for platinum, palladium and rhodium. Environ Sci Technol 35:835–839

    Article  CAS  Google Scholar 

  • Binet A, Volfin P (1977) Effect of an anti-tumor platinum complex, Pt(II)diaminotoluene, on mitochondrial-membrane properties. Biochim Biophys Acta 461:182–187

    Article  CAS  Google Scholar 

  • Bocca B, Caimi S, Smichowski P, Gomez D, Caroli S (2006) Monitoring Pt and Rh in urban aerosols from Buenos Aires, Argentina. Sci Total Environ 358:255–264

    Article  CAS  Google Scholar 

  • Brauer M, Hoek G, Smit HA, de Jongste JC, Gerritsen J, Postma DS, Kerkhof M, Brunekreef B (2007) Air pollution and development of asthma, allergy and infections in a birth cohort. Eur Respir J 29:879–888

    Article  CAS  Google Scholar 

  • Burnett RT, Smith-Doiron M, Stieb D, Cakmak S, Brook JR (1999) Effects of particulate and gaseous air pollution on cardiorespiratory hospitalizations. Arch Environ Health 54:130–139

    Article  CAS  Google Scholar 

  • Burnett RT, Brook J, Dann T, Delocla C, Philips O, Cakmak S, Vincent R, Goldberg MS, Krewski D (2000) Association between particulate- and gas-phase components of urban air pollution and daily mortality in eight Canadian cities. Inhal Toxicol 12:15–39

    Article  CAS  Google Scholar 

  • Caroli S, Alimonti A, Petrucci F, Bocca B, Krachler M, Forastiere F, Sacerdote MT, Mallone S (2001) Assessment of exposure to platinum-group metals in urban children. Spectrochim Acta B 56:1241–1248

    Article  Google Scholar 

  • Carter JD, Ghio AJ, Samet JM, Devlin RB (1997) Cytokine production by human airway epithelial cells after exposure to an air pollution particles is metal-dependent. Toxicol Appl Pharmacol 146:180–188

    Article  CAS  Google Scholar 

  • Columbo C, Monhemius AJ, Plant JA (2008a) Platinum, palladium and rhodium release from vehicle exhaust catalysts and road dust exposed to simulated lung fluids. Ecotoxicol Environ Safe 71:722–730

    Article  Google Scholar 

  • Columbo C, Monhemius AJ, Plant JA (2008b) The estimation of the bioavailabilities of platinum, palladium and rhodium in vehicle exhaust catalysts and road dusts using a physiologically based extraction test. Sci Total Environ 389:46–51

    Article  Google Scholar 

  • Costa DL, Dreher KL (1997) Bioavailable transition metals in particulate matter mediate cardiopulmonary injury in healthy and compromised animal models. Environ Health Perspect 105:1053–1060

    Google Scholar 

  • Cristaudo A, Sera F, Severino V, De Rocco M, Di Lella E, Picardo M (2005) Occupational hypersensitivity to metal salts, including platinum, in the secondary industry. Allergy 60:159–164

    Article  CAS  Google Scholar 

  • Dahlheimer SR, Neal CR, Fein JB (2007) Potential mobilization of platinum-group elements by siderophores in surface environments. Environ Sci Technol 41:870–875

    Article  CAS  Google Scholar 

  • Djingova R, Kovacheva P, Wagner G, Markert B (2003) Distribution of platinum group elements and other traffic related elements among different plants along some highways in Germany. Sci Total Environ 308:235–246

    Article  CAS  Google Scholar 

  • Dockery DW, Pope CA, Xu X, Spengler JD, Ware JH, Fay ME, Ferris BG, Speizer FE (1993) As association between air pollution and mortality in six US cities. N Engl J Med 329:1753–1759

    Article  CAS  Google Scholar 

  • Ek KH, Rauch S, Morrison GM, Lindberg P (2004) Platinum group elements in raptor eggs, faeces, blood, liver and kidney. Sci Total Environ 334/335:149–159

    Article  Google Scholar 

  • Frazzoli C, Dragone R, Mantovani A, Massimi C, Campanella L (2007) Functional toxicity and tolerance patterns of bioavailable Pd(II), Pt(II), and Rh(III) on suspended Saccharomyces cerevisiae cells assayed in tandem by a respirometric biosensor. Anal Bioanal Chem 89:2185–2194

    Article  Google Scholar 

  • Gagnon ZE, Newkirk C, Hicks S (2006) Impact of platinum group metals on the environment: a toxicological, genotoxic and analytical chemistry study. J Environ Sci Health A 41:397–414

    Article  CAS  Google Scholar 

  • Gagnon ZE, Patel A (2007) Induction of metallothionein in chick embryos as a mechanism of tolerance to platinum group metal exposure. J Environ Sci Health A 42:381–387

    CAS  Google Scholar 

  • Gebel T, Lantzsch H, Pleßow K, Dunkelberg H (1997) Genotoxicity of platinum and palladium compounds in human and bacterial cells. Mutat Res Gen Toxicol Environ Mutagen 389:183–190

    Article  CAS  Google Scholar 

  • Gomez B, Gomez M, Sanchez JL, Fernandez R, Palacios MA (2001) Platinum and rhodium distribution in airborne particulate matter and road dust. Sci Total Environ 269:131–144

    Article  CAS  Google Scholar 

  • Gomez B, Palacios MA, Gomez M, Sanchez JL, Morrison G, Rauch S, McLeod C, Ma R, Caroli S, Alimonti A, Petrucci F, Bocca B, Schramel P, Zischka M, Petterson C, Wass U (2002) Levels and risk assessment for humans and ecosystems of platinum-group elements in the airborne particles and road dust of some European cities. Sci Total Environ 299:1–19

    Article  CAS  Google Scholar 

  • Hatch GE, Slade R, Boykin E, Hu PC, Miller FJ, Gardner DE (1985) Correlation of effects of inhaled versus intratracheally-injected metals on susceptibility to respiratory tract infection in mice. Am J Respir Dis 124:167–173

    Google Scholar 

  • Helm D (2002) Association between palladium urinary concentrations and diseases of the thyroid and the immune system. Sci Total Environ 299:247–249

    Article  CAS  Google Scholar 

  • Höhr D, Steinfartz Y, Schins RPF, Knaapen AM, Martra G, Fubini B, Borm PJA (2002) The surface area rather than the surface coating determines the acute inflammatory response after instillation of fine and ultrafine TiO2 in the rat. Int J Hyg Environ Health 205:239–244

    Article  Google Scholar 

  • Iavicoli I, Bocca B, Petrucci F, Senofonte O, Carelli G, Alimonti A, Caroli S (2004) Biomonitoring of traffic police officers exposed to airborne platinum. Occup Environ Med 61:636–639

    Article  CAS  Google Scholar 

  • Iavicoli I, Carelli G, Marinaccio A, Fontana L, Calabrese EJ (2008) Effects of sub-chronic exposure to palladium (as potassium hexachloro-palladate) on cytokines in male Wistar rats. Hum Exp Toxicol 27:493–497

    Article  CAS  Google Scholar 

  • IARC (International Agency for Research on Cancer) (1981) Some antineoplastic and immunosuppressive agents: summary of data reported and evaluation. IARC monographs on the evaluation of carcinogenic risks to humans, vol 26. http://monographs.iarc.fr/ENG/Monographs/vol26/volume26.pdf. Accessed 10 May 2008

  • Janssen NAH, Brunekreef B, van Vliet P, Aarts F, Meliefste K, Harssema H, Fischer P (2003) The relationship between air pollution from heavy traffic and allergic sensitization, bronchial hyperresponsiveness, and respiratory symptoms in Dutch schoolchildren. Environ Health Perspect 111:1512–1518

    Article  Google Scholar 

  • Jarvis K, Parry S, Piper M (2001) Temporal and spatial studies of autocatalyst-derived platinum, rhodium, and palladium and selected vehicle-derived trace elements in the environment. Environ Sci Technol 35:1031–1036

    Article  CAS  Google Scholar 

  • Johnson Matthey (2007) Platinum—annual report. Johnson Matthey, London, p 104

    Google Scholar 

  • Kanitsar K, Koellensperger G, Hann S, Limbeck A, Puxbaum H, Stingeder G (2003) Determination of Pt, Pd and Rh by inductively coupled plasma sector field mass spectrometry (ICP-SFMS) in size-classified urban aerosol samples. J Anal At Spectrom 18:239–246

    Article  CAS  Google Scholar 

  • Klaassen CD, Lui J (1998) Induction of metallothionein as an adaptive mechanism affecting the magnitude and progression of toxicological injury. Environ Health Perspect 106:1–8

    Article  Google Scholar 

  • Kraemer SM (2004) Iron oxide dissolution and solubility in the presence of siderophores. Aquat Sci 66:3–18

    Article  CAS  Google Scholar 

  • Kränke B, Binder M, Derhaschnig J, Komericki P, Pirkhammer D, Ziegler V, Aberer W (1985) Epikutantestung mit der “Standardreihe Österreich”- Testepidemiologische Kenngrößen und Ergebnisse. Wien Klin Wochenschr 107:323–330

    Google Scholar 

  • Lustig S, Zang S, Beck W, Schramel P (1998) Dissolution of metallic platinum as water soluble species by naturally occurring complexing agents. Microchim Acta 129:189–194

    Article  CAS  Google Scholar 

  • Makri A, Goveia M, Balbus J, Parkin R (2004) Children’s susceptibility to chemicals: a review by developmental stage. J Toxicol Environ Health B 7:417–435

    Article  CAS  Google Scholar 

  • Merget R, Schultze-Werninghaus G, Muthorst T, Friedrich W, Meier-Sydow J (1988) Asthma due to the complex salts of platinum—a cross-sectional survey of workers in a platinum refinery. Clin Exp Allergy 18:569–580

    Article  CAS  Google Scholar 

  • Merget R, Rosner G (2001) Evaluation of the health risk of platinum group metals emitted from automotive catalytic converters. Sci Total Environ 270:165–173

    Article  CAS  Google Scholar 

  • Migliore L, Frenzilli G, Nesti C, Fortaner S, Sabbioni E (2002) Cytogenic and oxidative damage induced in human lymphocytes by platinum, rhodium and palladium compounds. Mutagenesis 17:411–417

    Article  CAS  Google Scholar 

  • Moldovan M, Rauch S, Gomez M, Palacios M, Morrison GM (2001) Bioaccumulation of palladium, platinum and rhodium from urban particulates and sediments by the freshwater isopod Asellus aquaticus. Water Res 35:4175–4183

    Article  CAS  Google Scholar 

  • Moldovan M, Palacios MA, Gomez MM, Morrison G, Rauch S, McLeod C, Ma R, Caroli S, Alimonti A, Petrucci F, Bocca B, Schramel P, Zischka M, Pettersson C, Wass U, Luna M, Saenz JC, Santamaría J (2002) Environmental risk of particulate and soluble platinum group elements released from gasoline and diesel engine catalytic converters. Sci Total Environ 296:199–208

    Article  CAS  Google Scholar 

  • Moore W, Hysell D, Crocker W, Stara J (1975) Biological fate of a single administration of 191Pt in rats following different routes of exposure. Environ Res 9:152–158

    Article  CAS  Google Scholar 

  • Nowack B, Kari FG, Krüger HG (2001) The remobilization of metals from iron oxides and sediments by metal-EDTA complexes. Water Air Soil Pollut 125:243–257

    Article  CAS  Google Scholar 

  • Orion E, Matz H, Wolf R (2003) Palladium allergy in an Israeli contact dermatitis clinic. Contact Dermatitis 49:216–217

    Article  Google Scholar 

  • Palacios M, Gomez M, Moldovan M, Morrison G, Rauch S, McLeod C, Ma R, Lacerna J, Lucena P, Caroli S, Alimonti A, Petrucci F, Bocca B, Schramel P, Lustig S, Zischka M, Wass U, Stenbom B, Luna M, Saenz J, Santamaria J, Torrens J (2000) Platinum group elements: quantification in collected exhaust fumes and studies of catalyst surfaces. Sci Total Environ 257:1–15

    Article  CAS  Google Scholar 

  • Park JD, Lui Y, Klaassen CD (2001) Protective effect of metallothionein against the toxicity of cadmium and other metals. Toxicology 163:93–100

    Article  CAS  Google Scholar 

  • Peijnenburg WJGM, Posthuma L, Eijsackers HJP, Allen EH (1997) A conceptual framework for implementation of bioavailability of metals for environmental management purposes. Ecotoxicol Environ Safe 37:163–172

    Article  CAS  Google Scholar 

  • Rauch S, Lu M, Morrison GM (2001) Heterogeneity of platinum group metals in airborne particles. Environ Sci Technol 35:595–599

    Article  CAS  Google Scholar 

  • Rauch S, Hemond HF, Peucker-Ehrenbrink B, Ek KH, Morrison GM (2005) Platinum group element concentrations and osmium isotopic composition in urban airborne particles from Boston, Massachusetts. Environ Sci Technol 39:9464–9470

    Article  CAS  Google Scholar 

  • Rauch S, Peucker-Ehrenbrink B, Molina LT, Molina MJ, Ramos R, Hemond H (2006) Platinum group elements in airborne particles in Mexico City. Environ Sci Technol 40:7554–7560

    Article  CAS  Google Scholar 

  • Ravindra K, Bencs L, Van Grieken R (2004) Platinum group elements in the environment and their health risk. Sci Total Environ 318:1–43

    Article  CAS  Google Scholar 

  • Rosen M, Figliomeni M, Simpkins H (1992) The interaction of platinum antitumor drugs with mouse-liver mitochondria. Int J Exp Pathol 73:61–74

    CAS  Google Scholar 

  • Santucci B, Valenzano C, de Rocco M, Cristaudo A (2000) Platinum in the environment: frequency of reactions to platinum-group elements in patients with dermatitis and urticaria. Contact Dermatitis 43:333–338

    Article  CAS  Google Scholar 

  • Schäfer J, Hannker D, Eckhardt JD, Stüben D (1998) Uptake of traffic-related heavy metals and platinum group elements (PGE) by plants. Sci Total Environ 215:59–67

    Article  Google Scholar 

  • Schierl R (2000) Environmental monitoring of platinum in air and urine. Microchem J 67:245–248

    Article  CAS  Google Scholar 

  • Schlögl R, Indlekofer G, Oelhafen P (1987) Mikropartikelemissionen von Verbrennungsmotoren mit Abgasreinigung, Röntgen-Photoelektronenspektroskopie in der Umweltanalytik. Angew Chem 99:312–322

    Article  Google Scholar 

  • Schmid M, Zimmermann S, Krug HF, Sures B (2007) Influence of platinum, palladium and rhodium as compared with cadmium, nickel and chromium on cell viability and oxidative stress in human bronchial epithelial cells. Environ Int 33:385–390

    Article  CAS  Google Scholar 

  • Shins RPF, Polat D, Begerow J, Turfeld M, Becker A, Borm PJA (2004) Platinum levels in nasal lavage fluid as a biomarker for traffic-related exposure and inflammation in children. Sci Total Environ 334/335:447–455

    Article  Google Scholar 

  • Schwartz J (1995) Short term fluctuations in air pollution and hospital admissions of the elderly for respiratory disease. Thorax 50:531–538

    Article  CAS  Google Scholar 

  • Sures B, Zimmermann S, Messerschmidt J, von Bohlen A, Alt F (2001) First report on the uptake of automobile catalyst emitted palladium by European eels (Anguilla anguilla) following experimental exposure to road dust. Environ Pollut 113:341–345

    Article  CAS  Google Scholar 

  • Vaughan GT, Florence TM (1992) Platinum in the human diet, blood, hair and excreta. Sci Total Environ 111:47–58

    Article  CAS  Google Scholar 

  • Ward JM, Young DM, Fauvie KA, Wolpert MK, Davis R, Guarino AM (1976) Comparative nephrotoxicity of platinum cancer chemotherapeutic agents. Cancer Treat Rep 60:1675–1678

    CAS  Google Scholar 

  • Wataha JC, Hanks CT, Sun Z (1995) In vitro reaction of macrophages to metal ions from dental biomaterials. Dent Mater 11:239–245

    Article  CAS  Google Scholar 

  • Watsky KL (2007) Occupational allergic contact dermatitis to platinum, palladium and gold. Contact Dermatitis 57:382–383

    Article  Google Scholar 

  • Whiteley JD, Murray F (2003) Anthropogenic platinum group element (Pt, Pd and Rh) concentrations in road dusts and roadside soils from Perth, Western Australia. Sci Total Environ 317:121–135

    Article  CAS  Google Scholar 

  • WHO (1991) Platinum. Environmental health criteria series, No. 125. International programme on chemical safety. WHO, Geneva, p 167

    Google Scholar 

  • WHO (2002) Palladium. Environmental health criteria series, No. 226. International program on chemical safety. WHO, Geneva, p 201

    Google Scholar 

  • Wigle DT, Arbuckle TE, Walker M, Wade MG, Liu S, Krewski D (2007) Environmental hazards: evidence for effects on child health. J Toxicol Environ Health B 10:3–39

    Article  CAS  Google Scholar 

  • Wilson MR, Lightbody JH, Donaldson K, Sales J, Stone V (2002) Interactions between ultrafine particles and transition metals in vivo and in vitro. Toxicol Appl Pharmacol 184:172–179

    Article  CAS  Google Scholar 

  • Winer AM, Behrentz E (2005) Estimates of nitrous oxide emissions from motor vehicles and the effects of catalyst composition and aging. Final report, submitted to the State of California Air Resources Board (Contract No. 02-313), p 216

    Google Scholar 

  • Wiseman CLS, Zereini F (2009) Airborne particulate matter, platinum group elements and human health: a review of recent evidence. Sci Total Environ 407:2493–2500

    Article  CAS  Google Scholar 

  • Wood SA (1996) The role of humic substances in the transport and fixation of metals of economic interest (Au, Pt, Pd, U, V). Ore Geol Rev 11:1–31

    Article  Google Scholar 

  • Zelikoff JT, Schermerhorn KR, Fang K, Cohen MD, Schlesinger RB (2002) A role for associated transition metals in the immunotoxicity of inhaled ambient particulate matter. Environ Health Perspect 110:871–875

    Article  CAS  Google Scholar 

  • Zereini F, Skerstupp B, Alt F, Helmers E, Urban H (1997) Geochemical behaviour of platinum-group elements (PGE) in particulate emissions by automobile exhaust catalysts: experimental results and environmental investigations. Sci Total Environ 206:137–146

    CAS  Google Scholar 

  • Zereini F, Golwer A (1999) Geochemisches Verhalten von Platinmetalle aus Autoabgaskatalysatoren in Sedimenten und im Wasser aus einem Versickerbecken. In: Zereini F, Alt F (eds) Emissionen von Platinmetallen: Analytik, Umwelt- und Gesundheitsrelevanz. Springer-Verlag, Berlin, pp 259–266

    Chapter  Google Scholar 

  • Zereini F, Wiseman C, Alt F, Messerschmidt J, Müller J, Urban H (2001) Platinum and rhodium concentrations in airborne particulate matter in Germany from 1988 to 1998. Environ Sci Technol 35:1996–2000

    Article  CAS  Google Scholar 

  • Zereini F, Alt F, Messerschmidt J, von Bohlen A, Liebl K, Püttmann W (2004) Concentration and distribution of platinum group elements (Pt, Pd, Rh) in airborne particulate matter in Frankfurt am Main, Germany. Environ Sci Technol 38:1686–1692

    Article  CAS  Google Scholar 

  • Zereini F, Alt F, Messerschmidt J, Wiseman C, Feldmann I, von Bohlen A, Müller J, Liebl K, Püttmann W (2005) Concentration and particle size distribution of heavy metals in urban airborne particulate matter in Frankfurt am Main, Germany. Environ Sci Technol 39:2983–2989

    Article  CAS  Google Scholar 

  • Zereini F, Wiseman C, Püttmann W (2007) Changes in palladium, platinum and rhodium concentrations and their spatial distribution in soils along a major highway in Germany from 1994 to 2004. Environ Sci Technol 41:451–456

    Article  CAS  Google Scholar 

  • Zimmermann S, Menzel CM, Stüben D, Taraschewski H, Sures B (2003) Lipid solubility of the platinum group metals Pt, Pd and Rh in dependence on the presence of complexing agents. Environ Pollut 124:1–5

    Article  CAS  Google Scholar 

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Wiseman, C.L., Zereini, F. (2010). Airborne Particulate Matter, Platinum Group Elements and Human Health. In: Zereini, F., Wiseman, C. (eds) Urban Airborne Particulate Matter. Environmental Science and Engineering(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-12278-1_28

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