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Flavonoid-Rich Nutrients for the Skin

Abstract

Flavonoids are a group of widespread plant constituents available from dietary sources such as cocoa, green tea, soy, berries, or other fruits like apples, lemons, cherries, plums, and peaches. There is evidence that flavonoid-rich products contribute to the protection of skin against UV-induced damage at the molecular and cellular level and that they may as well improve overall skin conditions. Regular intake or topical application confers significantly to photoprotection and helps maintaining skin health by improving skin structure and function. Photoprotective effects mediated by flavonoids are moderate but likely contribute to permanent, overall protection. Effects are comparable to those reported for other dietary constitutents such as carotenoids and other antioxidants.

Keywords

  • Hairless Mouse
  • Cocoa Product
  • Cocoa Powder
  • Ginkgo Biloba Extract
  • Pulse Wave Amplitude

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Fig. 8.1

References

  1. Afaq, F., Mukhtar, H.: Botanical antioxidants in the prevention of photocarcinogenesis and photoaging. Exp. Dermatol. 15, 678–684 (2006)

    CrossRef  CAS  PubMed  Google Scholar 

  2. Arct, J., Pytkowska, K.: Flavonoids as components of biologically active cosmeceuticals. Clin. Dermatol. 26, 347–357 (2008)

    CrossRef  PubMed  Google Scholar 

  3. Beecher, G.: Overview of dietary flavonoids: nomenclature, occurrence and intake. J. Nutr. 133, 3248S–3254S (2003)

    CAS  PubMed  Google Scholar 

  4. Boots, A.W., Haenen, G.R., Bast, A.: Health effects of quercetin: from antioxidant to nutraceutical. Eur. J. Pharmacol. 585(2–3), 325–337 (2008)

    CrossRef  CAS  PubMed  Google Scholar 

  5. Choquenet, B., Couteau, C., Paparis, E., Coiffard, L.J.M.: Quercetin and rutin as potential sunscreen agents: determination of efficacy by an in vitro method. J. Nat. Prod. 71, 1117–1118 (2008)

    CrossRef  CAS  PubMed  Google Scholar 

  6. Dinkova-Kostova, A.T.: Phytochemicals as protectors against ultraviolet radiation: versatility of effects and mechanisms. Planta Med 74, 1548–1559 (2008)

    CrossRef  CAS  PubMed  Google Scholar 

  7. Harnly, J.M., Doherty, R.F., Beecher, G.R., Holden, J.M., Haytowitz, D.B., Bhagwat, S., Gebhardt, S.: Flavonoid content of U.S. fruits, vegetables, and nuts. J. Agric. Food Chem. 54, 9966–9977 (2006)

    CrossRef  CAS  PubMed  Google Scholar 

  8. Heinrich, U., Neukam, K., Tronnier, H., Sies, H., Stahl, W.: Long-term ingestion of high flavanol cocoa provides photoprotection against UV-induced erythema and improves skin condition in women. J. Nutr. 136, 1565–1569 (2006)

    CAS  PubMed  Google Scholar 

  9. Heiss, C., Finis, D., Kleinbongard, P., Hoffmann, A., Rassaf, T., Kelm, M., Sies, H.: Sustained increase in flow-mediated dilation after daily intake of high-flavanol cocoa drink over 1 week. J. Cardiovasc. Pharmacol. 49, 74–80 (2007)

    Google Scholar 

  10. Heiss, C., Schroeter, H., Balzer, J., Kleinbongard, P., Matern, S., Sies, H., Kelm, M.: Endothelial function, nitric oxide, and cocoa flavanols. J. Cardiovasc. Pharmacol. 47, S128–S135 (2006)

    CrossRef  CAS  PubMed  Google Scholar 

  11. Hsu, S.: Green tea and the skin. J. Am. Acad. Dermatol. 52, 1049–1059 (2005)

    CrossRef  PubMed  Google Scholar 

  12. Katiyar, S.K.: Silymarin and skin cancer prevention: anti-inflammatory, antioxidant and immunomodulatory effects. Int. J. Oncol. 26, 169–176 (2005)

    CAS  PubMed  Google Scholar 

  13. Keen, C.L., Holt, R.R., Oteiza, P.I., Fraga, C.G., Schmitz, H.H.: Cocoa antioxidants and cardiovascular health. Am. J. Clin. Nutr. 81, 298S–303S (2005)

    CAS  PubMed  Google Scholar 

  14. Manach, C., Scalbert, A., Morand, C., Rémésy, C., Jiménez, L.: Polyphenols: food sources and bioavailability. Am. J. Clin. Nutr. 79, 727–747 (2004)

    CAS  PubMed  Google Scholar 

  15. Neukam, K., Stahl, W., Tronnier, H., Sies, H., Heinrich, U.: Consumption of flavanol-rich cocoa acutely increases microcirculation in human skin. Eur. J. Nutr. 46, 53–56 (2007)

    CrossRef  CAS  PubMed  Google Scholar 

  16. Rees, J.R., Stukel, T.A., Perry, A.E., Zens, M.S., Spencer, S.K., Karagas, M.R.: Tea consumption and basal cell and squamous cell skin cancer: results of a case-control study. J. Am. Acad. Dermatol. 56, 781–785 (2007)

    CrossRef  PubMed  Google Scholar 

  17. Sies, H., Stahl, W.: Nutritional protection against skin damage from sunlight. Ann. Rev. Nutr. 24, 173–200 (2004)

    CrossRef  CAS  Google Scholar 

  18. Solovchenko, A., Schmitz-Eiberger, M.: Significance of skin flavonoids for UV-B-protection in apple fruits. J. Exp. Bot. 54, 1977–1984 (2003)

    CrossRef  CAS  PubMed  Google Scholar 

  19. Stahl, W., Mukhtar, H., Afaq, F., Sies, H.: Vitamins and polyphenols in systemic photoprotection. In: Gilchrest, B.A., Krutmann, J. (eds.) Skin Aging. Springer, Berlin/Heidelberg (2006)

    Google Scholar 

  20. Steffen, Y., Gruber, C., Schewe, T., Sies, H.: Mono-O-methylated flavanols and other flavonoids as inhibitors of endothelial NADPH oxidase. Arch. Biochem. Biophys. 469, 206–219 (2008)

    CrossRef  Google Scholar 

  21. Stevenson, D.E., Hurst, R.D.: Polyphenolic phytochemicals–just antioxidants or much more? Cell. Mol. Life Sci. 64, 2900–2916 (2007)

    CrossRef  CAS  PubMed  Google Scholar 

  22. Uehara, M., Sugiura, H., Sakurai, K.: A trial of Oolong tea in the management of recalcitrant atopic dermatitis. Arch. Dermatol. 137, 42–43 (2001)

    CAS  PubMed  Google Scholar 

  23. Valko, M., Leibfritz, D., Moncol, J., Cronin, M.T., Mazur, M., Telser, J.: Free radicals and antioxidants in normal physiological functions and human disease. Int. J. Biochem. Cell Biol. 39, 44–84 (2007)

    CrossRef  CAS  PubMed  Google Scholar 

  24. Wolfe, K.L., Liu, R.H.: Structure–activity relationship of flavonoids in the cellular antioxidant activity assay. J. Agric. Food Chem. 56, 8404–8411 (2008)

    CrossRef  CAS  PubMed  Google Scholar 

  25. Yusuf, N., Irby, C., Katiyar, S.K., Elmets, C.A.: Photoprotective effects of green tea polyphenols. Photodermatol. Photoim­munol. Photomed. 23, 48–56 (2007)

    CrossRef  PubMed  Google Scholar 

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Acknowledgements Parts of our studies have been supported by the Deutsche Forschungsgemeinschaft (SFB 663, B1).

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Correspondence to Wilhelm Stahl .

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Stahl, W. (2010). Flavonoid-Rich Nutrients for the Skin. In: Krutmann, J., Humbert, P. (eds) Nutrition for Healthy Skin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-12264-4_8

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  • DOI: https://doi.org/10.1007/978-3-642-12264-4_8

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