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Bone Tumours: Work Up 2009

Imaging Algorithm in the Diagnosis, Therapy, Control and Follow-Up of Primary Musculoskeletal Tumours and Metastases
  • I. M. Noebauer-Huhmann
  • J. Panotopolous
  • R. I. Kotz
Chapter
Part of the European Instructional Lectures book series (EICL, volume 10)

Abstract

Fracture healing is a complex physiological process caused by the interaction of cellular elements that are activated and controlled by an array of cytokines and signalling proteins [11]. This process is both temporal and spatial in nature and usually results in the formation of new bone, which is structurally and mechanically similar to the pre-fracture state [10]. For al lot of reasons this process can fail and result in non-union of bone in 10% of all fractures and in up in 50% of open fractures of the tibia. These patients develop a non-union, which leads to long-lasting inability to work, loss of employment and high social costs. These cost are estimated in a paper of Sprague 2002 to be at approximately $80,000 in case of 18 weeks delay of fracture healing [28]. The overall costs of delayed fracture healing are estimated to be at $14.6 million in United States alone [6].

Keywords

Positron Emission Tomography Single Photon Emission Compute Tomography Standard Uptake Value Soft Tissue Tumour Fibrous Dysplasia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgement

We thank Teresa Zettl for the thorough ­administrative help

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Copyright information

© EFORT 2010

Authors and Affiliations

  • I. M. Noebauer-Huhmann
  • J. Panotopolous
  • R. I. Kotz
    • 1
  1. 1.Department of OrthopaedicMedizinische Universität WienViennaAustria

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