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Noninvasive Ventilation Pressure Adjustments in Patients with Amyotrophic Lateral Sclerosis

  • Kirsten L. GruisEmail author
Chapter

Abstract

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder of motor neurons. Patients with ALS develop diffuse skeletal muscle weakness in addition to respiratory muscle weakness, and respiratory failure is the most common cause of death. Tolerance to intermittent use of noninvasive ventilation (NIV) for 4 h or more a day is associated with improved survival and quality of life in patients with ALS [1, 5].

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Copyright information

© Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  1. 1.Department of Neurology, 1914/0316 Taubman CenterMotor Neuron Disease Center, University of Michigan Health SystemAnn ArborUSA

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