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Helicobacter-Related Gastritis and Ulceration and Investigation of Helicobacter pylori

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Esophageal and Gastric Disorders in Infancy and Childhood

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Abstract

Helicobacter pylori (H. pylori) infection occurs worldwide. Infection occurs most often in poor socioeconomic conditions and has been consistently linked to residential crowding and migration from high prevalence areas. Onset of infection occurs most frequently in childhood [1]. The mode of transmission of H. pylori has not been clearly identified. Evidence suggests that direct person-to-person transmission occurs, but the relative importance of the faecal-oral route or oral-oral route is not fully determined nor has the relevance of waterborne and zoonotic pathways been established [1]. Little is known regarding host factors that influence susceptibility to acquisition or persistence of infection.

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Acknowledgements

I would like to thank Dr K Venkatesh for his help with the literature search and Dr M Al-Adnani for the histological images of H. pylori.

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Authors and Affiliations

  1. Sheffield Children’s Hospital, Western Bank, Sheffield, S10 2TH, UK

    Priya Narula

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  1. Priya Narula
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Correspondence to Priya Narula .

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Editors and Affiliations

  1. Medical University of Graz, Graz, Austria

    Holger Till

  2. Sheffield Children’s Hospital, Paediatric Gastroenterology Centre, Sheffield, United Kingdom

    Mike Thomson

  3. Division of Cardiothoracic Surgery, Department of Surgery, University of Minnesota Medical School, Minneapolis, Minnesota, USA

    John E. Foker

  4. Department Surgery, University of Missouri, Kansas City Children’s Mercy Hospital, Kansas City, Missouri, USA

    George W. Holcomb III

  5. University of Arizona, Tucson, Arizona, USA

    Khalid M. Khan

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Narula, P. (2017). Helicobacter-Related Gastritis and Ulceration and Investigation of Helicobacter pylori . In: Till, H., Thomson, M., Foker, J., Holcomb III, G., Khan, K. (eds) Esophageal and Gastric Disorders in Infancy and Childhood. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-11202-7_119

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