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Long-term IGF-I treatment changed the craniofacial morphology and increased head circumference (i.e. brain growth) to normal values.
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References
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Laron, Z. (2011). IGF-I Stimulation of Head Growth in Patients with Laron Syndrome. In: Laron, Z., Kopchick, J. (eds) Laron Syndrome - From Man to Mouse. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-11183-9_43
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DOI: https://doi.org/10.1007/978-3-642-11183-9_43
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