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Stereotactic Radiosurgery for Movement Disorders

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Shaped Beam Radiosurgery

Abstract

Stereotactic radiosurgery (SRS) was developed with the aim of creating a minimally invasive technique capable of precisely generating a focal lesion in the brain. In his first procedure, Lars Leksell used an orthovoltage X-ray source adapted to his arc-centered stereotactic frame to treat a trigeminal neuralgia patient (Leksell 1951). At that point, his main goal was to develop a device to treat functional disorders of the brain, including intractable pain, movement disorders, and epilepsy. Although Leksell and his group described the utility of SRS in functional diseases (Leksell 1968; Steiner et al. 1980), the technique has advanced and proved its invaluable utility in the treatment of other major neurosurgical pathologies including brain arteriovenous malformations, metastases, malignant and benign tumors of the brain and skull base (De Salles et al. 2008; Friedman and Bova 1992; Kondziolka et al. 2008a; Sneed et al. 2002).

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References

  • Alterman RL, Kall BA, Cohen H et al (1995) Stereotactic ventrolateral thalamotomy: is ventriculography necessary? Neurosurgery 37:717–722

    Article  PubMed  CAS  Google Scholar 

  • Bednarz G, Downes MB, Corn BW, Curran WJ, Goldman HW (1999) Evaluation of the spatial accuracy of magnetic resonance imaging-based stereotactic target localization for gamma knife radio-surgery of functional disorders. Neurosurgery 45:1156–1161, Discussion 61–63

    Article  PubMed  CAS  Google Scholar 

  • Benabid AL, Benazzouz A, Hoffmann D et al (1998) Long-term electrical inhibition of deep brain targets in movement disorders. Mov Disord 13(Suppl 3):119–125

    PubMed  Google Scholar 

  • Bonnen JG, Iacono RP, Lulu B, Mohamed AS, Gonzalez A, Schoonenberg T (1997) Gamma knife pallidotomy: case report. Acta Neurochir 139:442–445

    Article  CAS  Google Scholar 

  • Burchiel KJ, Anderson VC, Favre J, Hammerstad JP (1999) Comparison of pallidal and subthalamic nucleus deep brain stimulation for advanced Parkinson’s disease: results of a randomized, blinded pilot study. Neurosurgery 6:1375–1382, Discussion 1382–1384

    Article  Google Scholar 

  • De Salles AA, Melega WP, Lacan G, Steele LJ, Solberg TD (2001) Radiosurgery performed with the aid of a 3-mm ­collimator in the subthalamic nucleus and substantia nigra of the vervet monkey. J Neurosurg 95:990–997

    Article  PubMed  Google Scholar 

  • De Salles AA, Gorgulho AA, Selch M, De Marco J, Agazaryan N (2008) Radiosurgery from the brain to the spine: 20 years experience. Acta Neurochir Suppl 101:163–168

    Article  PubMed  Google Scholar 

  • Dogali M, Fazzini E, Kolodny E et al (1995) Stereotactic ventral pallidotomy for Parkinson’s disease. Neurology 45: 753–761

    Article  PubMed  CAS  Google Scholar 

  • Duma CM (2007) Movement disorder radiosurgery—planning, physics and complication avoidance. Prog Neurol Surg 20: 249–266

    Article  PubMed  Google Scholar 

  • Duma CM, Jacques DB, Kopyov OV et al (1998) Gamma knife radiosurgery for thalamotomy in parkinsonian tremor: a five-year experience. J Neurosurg 88:1044–1049

    Article  PubMed  CAS  Google Scholar 

  • Duma CM, Jacques K, Kopyov OV (1999) Treatment of movement disorders using gamma knife stereotactic radiosurgery. Neurosurg Clin N Am 10:379–389

    PubMed  CAS  Google Scholar 

  • Fahn S, Tolosa E, Marin C (1993) Clinical rating scale for tremor. Parkinson’s disease and movement disorders, 2nd edn. William & Wilkins, Baltimore, pp 271–280

    Google Scholar 

  • Friedman WA, Bova FJ (1992) Linear accelerator radiosurgery for arteriovenous malformations. J Neurosurg 77(6):832–841

    Article  PubMed  CAS  Google Scholar 

  • Friedman DP, Epstein M, Sanes JN et al (1996) Gamma knife pallidotomy in advanced Parkinson’s disease. Ann Neurol 39:535–538

    Article  PubMed  CAS  Google Scholar 

  • Friedman DP, Goldman HW, Flanders AE, Gollomp SM, Curran WJ Jr (1999) Stereotactic radiosurgical pallidotomy and thalamotomy with the gamma knife: MR imaging findings with clinical correlation – preliminary experience. Radiology 212:143–150

    PubMed  CAS  Google Scholar 

  • Friedman JH, Fernandez HH, Sikirica M, Stopa E, Friehs G (2002) Stroke induced by gamma knife pallidotomy: autopsy result. Neurology 58:1695–1697

    Article  PubMed  CAS  Google Scholar 

  • Friehs GM, Ojakangas CL, Pachatz P et al (1995) Thalamotomy and caudatotomy with the gamma knife as a treatment for parkinsonism with a comment on lesion sizes. Stereotact Funct Neurosurg 64(Suppl 1):209–221

    PubMed  Google Scholar 

  • Friehs GM, Norén G, Ohye C et al (1996) Lesion size following gamma knife treatment for functional disorders. Stereotact Funct Neurosurg 66(Suppl 1):320–328

    Article  PubMed  Google Scholar 

  • Frighetto L, De Salles A, Wallace R, Ford J, Selch M, Cabatan-Awang C, Solberg T (2004) Linear accelerator thalamotomy. Surg Neurol 62(2):106–113, Discussion 113–114

    Article  PubMed  Google Scholar 

  • Goldman MS, Kelly PJ (2000) Stereotactic thalamotomy for medically intractable essential tremor. N Engl J Med 342: 461–468

    Article  Google Scholar 

  • Hariz MI, Bergenheim AT (2001) A 10-year follow-up review of patients who underwent Leksell’s posteroventral ­pallidotomy for Parkinson disease. J Neurosurg 94(4): 552–558

    Article  PubMed  CAS  Google Scholar 

  • Jankovic J, Cardoso F, Grossman RG et al (1995) Outcome after stereotactic thalamotomy for parkinsonian essential and other types of tremor. Neurosurgery 37:680–687

    Article  PubMed  CAS  Google Scholar 

  • Kihlström L, Guo WY, Lindquist C et al (1995) Radiobiology of radiosurgery for refractory anxiety disorders. Neurosurgery 36:294–302

    Article  PubMed  Google Scholar 

  • Kondziolka D, Mathieu D, Lunsford LD, Martin JJ, Madhok R, Niranjan A, Flickinger JC (2008a) Radiosurgery as definitive management of intracranial meningiomas. Neurosurgery 62(1):53–58, Discussion 58–60

    Article  PubMed  Google Scholar 

  • Kondziolka D, Ong J, Lee J, Moore R, Flickinger J, Lunsford D (2008b) Gamma Knife thalamotomy for essential tremor. J Neurosurg 108(1):111–117

    Article  PubMed  Google Scholar 

  • Laitinen LV, Bergenheim AT, Hariz MI (1992) Leksell’s posteroventral pallidotomy in the treatment of Parkinson’s disease. J Neurosurg 76:53–61

    Article  PubMed  CAS  Google Scholar 

  • Leksell L (1951) The stereotaxic method and radiosurgery of the brain. Acta Chir Scand 102:316–319

    PubMed  CAS  Google Scholar 

  • Leksell L (1968) Cerebral radiosurgery. I. Gammathalanotomy in two cases of intractable pain. Acta Chir Scand 134: 585–595

    PubMed  CAS  Google Scholar 

  • Lindquist C, Kihlstrom L, Hellstrand E (1991) Functional neurosurgery – a future for the gamma knife? Stereotact Funct Neurosurg 57:72–81

    Article  PubMed  CAS  Google Scholar 

  • Lindquist C, Steiner L, Hindmarsh T (1992) Gamma knife thalamotomy for tremor: report of two cases. In: Steiner L, Lindquist C, Forster D (eds) Radiosurgery: baseline and trends. Raven, New York, pp 237–243

    Google Scholar 

  • Linhares MN, Tasker RR (2000) Microelectrode-guided thalamotomy for Parkinson’s disease. Neurosurgery 46:390–395

    Article  PubMed  CAS  Google Scholar 

  • Lozano A, Hutchison W, Kiss Z et al (1996) Methods for micro-electrode-guided posteroventral pallidotomy. J Neurosurg 84:194–202

    Article  PubMed  CAS  Google Scholar 

  • Martínez-Martín P, Gil-Nagel A, Gracia LM, Gómez JB, Martínez-Sarriés J, Bermejo F (1994) Unified Parkinson’s disease rating scale characteristics and structure. The Cooperative Multicentric Group. Mov Disord 9(1):76–83

    Article  PubMed  Google Scholar 

  • Novotny J Jr, Vymazal J, Novotny J, Tlachacova D, Schmitt M, Chuda P, Urgosik D, Liscak R (2005) Does new magnetic resonance imaging technology provide better geometrical accuracy during stereotactic imaging? J Neurosurg 102(Suppl):8–13

    Article  PubMed  Google Scholar 

  • Ohye C (2006) From selective thalamotomy with microrecording to gamma thalamotomy for movement disorders. Stereotact Funct Neurosurg 84:155–161

    Article  PubMed  Google Scholar 

  • Ohye C, Shibazaki T (2002) Location of the thalamic Vim nucleus. Its relation to the whole thalamic length. Funct Neurosurg 41:52–53

    Google Scholar 

  • Ohye C, Shibazaki T, Hirato M, Inoue H, Andou Y (1996) Gamma thalamotomy for parkinsonian and other kinds of tremor. Stereotact Funct Neurosurg 66(1 Suppl):333–342

    Article  PubMed  Google Scholar 

  • Ohye C, Shibazaki T, Ishihara J, Zhang J (2000) Evaluation of gamma thalamotomy for parkinsonian and other tremors: survival of neurons adjacent to the thalamic lesion after gamma thalamotomy. J Neurosurg 93(3 Suppl):120–127

    PubMed  Google Scholar 

  • Ohye C, Shibazaki T, Zhang J, Andou Y (2002) Thalamic lesions produced by gamma thalamotomy for movement disorders. J Neurosurg 97(5 Suppl):600–606

    PubMed  Google Scholar 

  • Ohye C, Shibazaki T, Sato S (2005) Gamma knife thalamotomy for movement disorders: evaluation of the thalamic lesion and clinical results. J Neurosurg 102(Suppl):234–240

    Article  PubMed  Google Scholar 

  • Pan L, Dai J, Wang B et al (1996) Stereotactic gamma knife thalamotomy for the treatment of parkinsonism. Stereotact Funct Neurosurg 66(Suppl 1):329–332

    Article  PubMed  Google Scholar 

  • Rand RW, Jacques DB, Melbye RW et al (1993) Gamma knife thalamotomy and pallidotomy in patients with movement disorders: preliminary results. Stereotact Funct Neurosurg 61(Suppl 1):65–92

    Article  PubMed  Google Scholar 

  • Smith ZA, De Salles AA, Frighetto L, Goss B, Lee SP, Selch M et al (2003) Dedicated linear accelerator radiosurgery for the treatment of trigeminal neuralgia. J Neurosurg 99:511–516

    Article  PubMed  Google Scholar 

  • Sneed PK, Suh JH, Goetsch SJ, Sanghavi SN, Chappell R, Buatti JM, Regine WF, Weltman E, King VJ, Breneman JC, Sperduto PW, Mehta MP (2002) A multi-institutional review of radiosurgery alone vs. radiosurgery with whole brain radiotherapy as the initial management of brain metastases. Int J Radiat Oncol Biol Phys 53(3):519–526

    Article  PubMed  Google Scholar 

  • Solberg TD, DeSalles AAF, Medin PM, DeMarco JJ, Selch MT (1998) Technical aspects of LINAC radiosurgery for the treatment of small functional targets. J Radiosurg 1:115–127

    Article  Google Scholar 

  • Starr PA, Vitek JL, Bakay RA (1998) Ablative surgery and deep brain stimulation for Parkinson’s disease. Neurosurgery 43: 989–1015

    Article  PubMed  CAS  Google Scholar 

  • Steiner L, Forster D, Leksell L et al (1980) Gammathalamotomy in intractable pain. Acta Neurochir 52:173–184

    Article  CAS  Google Scholar 

  • Sumanaweera TS, Adler JR Jr, Napel S et al (1994) Characterization of spatial distortion in magnetic resonance imaging and its implications for stereotactic surgery. Neurosurgery 35:696–704

    Article  PubMed  CAS  Google Scholar 

  • Tasker RR, Munz M, Junn FS et al (1997) Deep brain stimulation and thalamotomy for tremor compared. Acta Neurochir Suppl 68:49–53

    PubMed  CAS  Google Scholar 

  • Young RF, Jacques DS, Rand RW et al (1994) Medial thalamotomy with the Leksell gamma knife for treatment of chronic pain. Acta Neurochir Suppl 62:105–110

    Article  PubMed  CAS  Google Scholar 

  • Young RF, Jacques DS, Rand RW et al (1995) Technique of stereotactic medial thalamotomy with the Leksell gamma knife for treatment of chronic pain. Neurol Res 17:59–65

    PubMed  CAS  Google Scholar 

  • Young RF, Vermeulen SS, Grim P et al (1996) Electrophysiological target localization is not required for the treatment of functional disorders. Stereotact Funct Neurosurg 66(Suppl 1): 309–319

    Article  PubMed  Google Scholar 

  • Young RF, Shumway-Cook A, Vermeulen SS et al (1998a) Gamma knife radiosurgery as a lesioning technique in movement disorder surgery. J Neurosurg 89:183–193

    Article  PubMed  CAS  Google Scholar 

  • Young RF, Vermeulen S, Posewitz A, Shumway-Cook A (1998b) Pallidotomy with the gamma knife: a positive experience. Stereotact Funct Neurosurg 70(1 Suppl):218–228

    Article  PubMed  Google Scholar 

  • Young RF, Jacques S, Mark R, Kopyov O, Copcutt B, Posewitz A et al (2000) Gamma knife thalamotomy for treatment of tremor: long-term results. J Neurosurg 93(3 Suppl): 128–135

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Neurosurgery, Stereotactic Radiosurgery Section, Moinhos de Vento Hospital, Rua Tiradentes 333, 90560–030, Porto Alegre, RS, Brazil

    Leonardo Frighetto, Jorge Bizzi & Paulo Oppitz

Authors
  1. Leonardo Frighetto
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  2. Jorge Bizzi
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  3. Paulo Oppitz
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Corresponding author

Correspondence to Leonardo Frighetto .

Editor information

Editors and Affiliations

  1. David Geffen School of Medicine at UCLA, Department of Neurosurgery and Radiation, University of California, Le Conte Ave. 10495, Los Angeles, 90095, California, USA

    Antonio A. F. De Salles

  2. UCLA Medical Center, Department of Neurosurgery, University of California, Le Conte Ave 10945, Los Angeles, 90095, California, USA

    Alessandra Gorgulho

  3. David Geffen School of Medicine, Dept. Radiation Oncology, University of California, Los Angeles, UCLA Medical Plaza 200, Los Angeles, 90095, California, USA

    Nzhde Agazaryan

  4. , Department of Radiation Oncology, VU University Medical Center, De Boelelaan 1117, Amsterdam, 1081 HV, Netherlands

    Ben Slotman

  5. David Geffen School of Medicine at UCLA, Department of Radiation Oncology, University of California, UCLA Medical Plaza 200, Los Angeles, 90095, California, USA

    Michael Selch

  6. BrainLAB, Inc., Westbrook Corporate Center 3, Westchester, 60154, Illinois, USA

    Aaaron J. Burwick

  7. Shaped-Beam Radiosurgery, Varian Medical Systems, Inc., Hansen Way 3100, Palo Alto, 94304, California, USA

    Raymond Schulz

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Frighetto, L., Bizzi, J., Oppitz, P. (2011). Stereotactic Radiosurgery for Movement Disorders. In: De Salles, A., et al. Shaped Beam Radiosurgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-11151-8_18

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  • DOI: https://doi.org/10.1007/978-3-642-11151-8_18

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