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The Function of Cyclic Nucleotide-Gated Channels in Biotic Stress

Chapter
Part of the Signaling and Communication in Plants book series (SIGCOMM)

Abstract

Plant cyclic nucleotide-gated ion channels conduct Ca2+ across the plasma membrane (PM) and facilitate cytosolic Ca2+ elevation during pathogen response signaling cascades. Until recently, not much was known about the specific ion channels involved in Ca2+ influx into plant cells, or how Ca2+ signals are generated and impact on downstream events during pathogen resistance responses. Recent studies, involving the cyclic nucleotide gated ion channel (CNGC) family of proteins, have provided new information relevant to these two areas of plant biology and will be reviewed in this chapter. Current evidence points to specific proteins that synthesize cyclic nucleotides and that function as ligands to activate CNGCs. The role of these channels in Ca2+ conduction appears critical to the generation of the hypersensitive response to pathogens, an important defense mechanism that limits disease in plants. Signaling downstream from Ca2+ during biotic stress responses involves cytosolic Ca2+-binding proteins such as calmodulin.

Keywords

Nitric Oxide Hypersensitive Response Cyclic Nucleotide Avirulent Pathogen Vacuolar Processing Enzyme 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations

AC

Adenylyl cyclase

avr

Avirulence

CaM

Calmodulin

CML

CaM-like protein

CDPK

Ca2+-dependent protein kinase

CNBDs

Cyclic nucleotide binding domains

CNGC

Cyclic nucleotide gated channel

GC

Guanylyl cyclase

HR

Hypersensitive response

LPS

Lipopolysaccharide

LRR-RLKs

Leucine-rich-repeat receptor-like kinases

NC

Nucleotidyl cyclase

NO

Nitric oxide

NOS

Nitric oxide synthase

PAMP

Pathogen-associated molecular pattern

PCD

Programmed cell death

PM

Plasma membrane

ROS

Reactive oxygen species

SA

Salicylic acid

TM

Transmembrane

VPE

Vacuolar processing enzyme

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Copyright information

© Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  1. 1.Agricultural Biotechnology Laboratory, Department of Plant ScienceUniversity of ConnecticutStorrsUSA
  2. 2.Department of Cell and Systems BiologyUniversity of TorontoTorontoCanada
  3. 3.Department of BiotechnologyUniversity of the Western CapeBellvilleSouth Africa

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