Innovative Drugs and Biomedical Engineering

Abstract

In the recent 20 years, rapid improvement has taken place in the research and development (R&D) of innovative drugs, which mostly manifested in the following two aspects. On one hand, with the advancement of genomics, proteomics, systems biology, stem cell research and other modern biotechnologies, more and more details have been revealed relative to mechanisms of disease etiology which further facilitates the discovery and validation of novel targets and changes the thought and the model of developing new drug; on the other hand, burgeoning sciences such as structural biology, computer and information technologies are emerged in early stage of drug discovery and research deeply more and more, while continuous cross-fostering with chemistry and physics brings about dramatic changes in the landscape of innovative drug development.