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Benign Tumors

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References

  1. Altmann HW (1994) Hepatic neoformations. Path Res Pract 190: 513–77

    CAS  PubMed  Google Scholar 

  2. Anthony PP (1994) Tumours and tumour-like lesions of the liver and biliray tract. In: MacSween RNM, Anthony PP, Scheuer PJ, et al (eds) Pathology of the liver, 3rd ed. Churchill Livingstone, Edinburgh, pp 635–711

    Google Scholar 

  3. International Working Party of World Congress of Gastroenterology (1995) Terminology of nodular lesions of the liver. Hepatology 22: 983–93

    Google Scholar 

  4. Ishak KG, Anthony PP, Sobin LH (1994) WHO histological typing of tumours of the liver, 2nd ed. Springer, Berlin/ Heidelberg/New York

    Google Scholar 

  5. Ishak KG, Goodman ZD, Stocker JT (2001) Tumors of the liver and intrahepatic bile ducts. Armed Forces Institute of Pathology, Washington DC

    Google Scholar 

  6. Wittekind C, Tannapfel A (2000) Tumoren der leber. In: Denk H, Dienes HP, Düllmann J, et al (eds) Pathologie der Leber und der Gallenwege. Springer, Berlin/Heidelberg/ New York

    Google Scholar 

References

  1. Bacq Y, Jaquemin E, Balabaud C, et al (2003) Familial liver adenomatosis associated with hepatocyte nuclear factor 1α inactivation. Gastroenterology 125: 1470–5

    Article  PubMed  Google Scholar 

  2. Bioulac-Sage P, Rebouissou S, Thomas C, et al (2007) Hepatocellular adenoma subtype classification using molecular markers and immunohistochemistry. Hepatology 46: 740–8

    Article  CAS  PubMed  Google Scholar 

  3. Burri E, Steuerwald M, Cathomas G, et al (2006) Hepatocellular carcinoma in a liver-cell adenoma within a non-cirrhotic liver. Eur J Gastroenterol Hepatol 18: 437–41

    Article  PubMed  Google Scholar 

  4. Chen YW, Jeng YM, Yeh SH, et al (2002) p53 gene and Wnt signaling in benign neoplasms: βcatenin mutations in hepatic adenoma but not in focal nodular hyperplasia. Hepatology 36: 927–35

    CAS  PubMed  Google Scholar 

  5. Chiche L, Dao T, Salame E, et al (2000) Liver adenomatosis: reappraisal, diagnosis, and surgical management: eight new cases and review of the literature. Ann Surg 231: 74–81

    Article  CAS  PubMed  Google Scholar 

  6. Chung AYF, Leo KW, Wong GC, et al (2006) Giant hepato-cellular adenoma presenting with chronic iron deficiency anemia. Am J Gastroenterol 101: 2160–2

    Article  PubMed  Google Scholar 

  7. Cohen C, Lawson D, DeRose PB (1998) Sex and androgenic steroid receptor expression in hepatic adenomas. Hum Pathol 29: 1428–32

    Article  CAS  PubMed  Google Scholar 

  8. Cosme A, Horrajada JP, Vidaur F, et al (1995) Systemic amyloidosis induced by oral contraceptive-associated hepatocellular adenoma: a 13 year follow up. Liver 15: 164–7

    CAS  PubMed  Google Scholar 

  9. Edmondson HA, Henderson B, Benton B (1976) Liver cell adenomas associated with the use of oral contraceptives. N Engl J Med 294: 470–2

    Article  CAS  PubMed  Google Scholar 

  10. Foster JH, Berman MM (1994) The malignant transformation of liver cell adenomas. Arch Surg 129: 712–7

    CAS  PubMed  Google Scholar 

  11. Gouysse G, Frachon S, Hervieu V, et al (2004) Endothelial cell differentiation in hepatocellular adenomas: implications for histopathological diagnosis. J Hepatol 41: 259–66

    Article  PubMed  Google Scholar 

  12. Grazioli L, Federle MP, Ishikawa T, et al (2000) Liver ade-nomatosis: clinical, histopathologic, and imaging findings in 15 patients. Radiology 216: 395–402

    CAS  PubMed  Google Scholar 

  13. Khoo US, Nicholls JM, Lee JS, et al (1994) Cholestatic liver cell adenoma in a child with hirsutism and elevated serum levels of cortisol and ACTH. Histopathology 25: 586–8

    Article  CAS  PubMed  Google Scholar 

  14. Laumonier H, Bioulac-Sage P, Laurent C, et al (2008) Hepatocellular adenomas: magnetic resonance imaging features as a function of molecular pathological classification. Hepatology 48: 808–18

    Article  PubMed  Google Scholar 

  15. Paradis V, Benzekri A, Dargere D, et al (2004) Telangiectatic focal nodular hyperplasia: a variant of hepatocellular adenoma. Gastroenterology 126: 1323–9

    Article  PubMed  Google Scholar 

  16. Paradis V, Champault A, Ronot M, et al (2007) Telangiectatic adenoma: an entity associated with increased body mass index and inflammation. Hepatology 46: 140–6

    Article  PubMed  Google Scholar 

  17. Rebouissou S, Bioulac-Sage P, Zucman-Rossi J (2008) Molecular pathogenesis of focal nodular hyperplasia and hepatocellular adenoma. J Hepatol 48: 163–70

    Article  CAS  PubMed  Google Scholar 

  18. Rooks JB, Ory HW, Ishak KG, et al (1979) Epidemiology of hepatocellular adenoma. The role of oral contraceptive use. JAMA 242: 644–8

    Article  CAS  PubMed  Google Scholar 

  19. Smit GP, Fernandes J, Leonard J V, et al (1990) The long-term outcome of patients with glycogen storage diseases. J Inher Metab Dis 13: 411–8

    Article  CAS  PubMed  Google Scholar 

  20. Tannapfel A, Busse C, Geißler F, et al (2002) INK4αARF alterations in liver cell adenoma. Gut 51: 253–8

    Article  CAS  PubMed  Google Scholar 

  21. Terkivatan T, de Wilt JH, de Man RA, et al (2001) Indications and long-term outcome of treatment for benign hepatic tumors: a critical appraisal. Arch Surg 136: 1033–8

    Article  CAS  PubMed  Google Scholar 

  22. Thyssell H, Ingvar C, Gustafson T, et al (1986) Systemic reactive amyloidosis caused by hepatocellular adenoma. A case report. J Hepatol 2: 450–7

    Article  Google Scholar 

  23. Zucman-Rossi J, Jeannot E, Van Nhieu JT, et al (2006) Genotype-phenotype correlation in hepatocellular adenoma: new classification and relationship with HCC. Hepatology 43: 515–24

    Article  CAS  PubMed  Google Scholar 

Refrences

  1. Colina F, Alberti N, Solis JA, et al (1989) Diffuse nodular regenerative hyperplasia of the liver (DNRH). A clinico-pathological study of 24 cases. Liver 9: 253–65

    CAS  PubMed  Google Scholar 

  2. Croquelois A, Blindenbacher A, Terraciano I, et al (2005) Inducible inactivation of notch 1 causes nodular regenerative hyperplasia in mice. Hepatology 41: 487–96

    Article  CAS  PubMed  Google Scholar 

  3. Dumortier J, Boillot O, Chevallier M, et al (1999) Familial occurrence of nodular regenerative hyperplasia of the liver: a report on three families. Gut 45: 289–94

    Article  CAS  PubMed  Google Scholar 

  4. Ferlitsch A, Teml A, Reinisch W, et al (2007) 6-thioguanine associated nodular regenerative hyperplasia in patients with inflammatory bowel disease may induce portal hypertension. Am J Gastroenterol 102: 2495–503

    Article  CAS  PubMed  Google Scholar 

  5. Hubert C, Sempoux C, Horsmans Y, et al (2007) Nodular regenerative hyperplasia: a deleterious consequence of chemotherapy for colorectal liver metastases? Liver Int 27: 938–43

    Article  CAS  PubMed  Google Scholar 

  6. Kondo F (2001) Benign nodular hepatocellular lesions caused by abnormal hepatic circulation: etiological analysis and introduction of a new concept. J Gastroenterol Hepatol 16: 1319–28

    Article  CAS  PubMed  Google Scholar 

  7. Malamut G, Ziol M, Suarez F, et al (2008) Nodular regenerative hyperplasia: the main liver disease in patients with primary hypogammaglobulinemia and hepatic abnormalities. J Hepatol 48: 74–82

    Article  PubMed  Google Scholar 

  8. Nakhleh RE, Snover DC (1988) Use of alpha-1-antitrypsin in the diagnosis of nodular regenerative hyperplasia of the liver. Hum Pathol 19: 1048–52

    Article  CAS  PubMed  Google Scholar 

  9. O'Brien K, Hussein N, Warady BA, et al (2006) Nodular regenerative hyperplasia and severe portal hypertension in cystinosis. Clin Gastroenterol Hepatol 4: 387–94

    Article  PubMed  Google Scholar 

  10. Ranstrom S (1953) Miliary hepatocellular adenomatosis. Acta Pathol Microbiol Scand 33: 225–9

    Article  CAS  PubMed  Google Scholar 

  11. Reshamwala PA, Kleiner DE, Heller T (2006) Nodular regenerative hyperplasia: not all nodules are created equal. Hepatology 44: 7–14

    Article  PubMed  Google Scholar 

  12. Russmann S, Zimmermann A, Krähenbühl S, et al (2001) Veno-occlusive disease, nodular regenerative hyperplasia and hepatocellular carcinoma after treatment in a patient with ulcerative colitis. Eur J Gastroenterol Hepatol 13: 287–90

    Article  CAS  PubMed  Google Scholar 

  13. Steiner PE (1959) Nodular regenerative hyperplasia of the liver. Am J Pathol 35: 943–53

    CAS  PubMed  Google Scholar 

  14. Stromeyer FW, Ishak KG (1981) Nodular transformation (nodular regenerative hyperplasia) of the liver. A clinico-pathologic study of 30 cases. Hum Pathol 12: 60–71

    Article  CAS  PubMed  Google Scholar 

  15. Wanless IR (1990) Micronodular transformation (nodular regenerative hyperplasia) of the liver: a report of 64 cases among 2,500 autopsies and a new classification of benign hepatocellular nodules. Hepatology 11: 787–97

    Article  CAS  PubMed  Google Scholar 

References

  1. Bioulac-Sage P, Rebouissou S, Sa Cunha A, et al (2005) Clinical, morphologic, and molecular features defining so-called telangiectatic focal nodular hyperplasias of the liver. Gastroenterology 128: 1211–8

    Article  PubMed  Google Scholar 

  2. Boulahdour H, Cherqui D, Charlotte F, et al (1993) The hot spot hepatobiliary scan in focal nodular hyperplasia. J Nucl Med 34: 2105–10

    CAS  PubMed  Google Scholar 

  3. Butron Vila MM, Haot J, Desmet VJ (1984) Cholestatic features in focal nodular hyperplasia of the liver. Liver 4: 387–95

    CAS  PubMed  Google Scholar 

  4. Cherqui D, Rahmouni A, Charlotte F, et al (1995) Management of focal nodular hyperplasia and hepatocellular adenoma in young women: a series of 41 patients with clinical, radiological, and pathological correlations. Hepatology 22: 1674–81

    Article  CAS  PubMed  Google Scholar 

  5. Fabre A, Audet P, Vilgrain V, et al (2002) Histologic scoring of liver biopsy in focal nodular hyperplasia with atypical presentation. Hepatology 35: 414–20

    Article  PubMed  Google Scholar 

  6. Fukukura Y, Nakashima O, Kusaba A, et al (1998) Angioarchitecture and blood circulation in focal nodular hyperplasia of the liver. J Hepatol 29: 470–5

    Article  CAS  PubMed  Google Scholar 

  7. Gaffey MJ, Iezzoni JC, Weiss LM (1996) Clonal analysis of focal nodular hyperplasia of the liver. Am J Pathol 148: 1089–96

    CAS  PubMed  Google Scholar 

  8. Goldin RD, Rose DS (1990) Focal nodular hyperplasia of the liver associated with intracranial vascular malformation. Gut 31: 554–5

    Article  CAS  PubMed  Google Scholar 

  9. Luciani A, Kobeiter H, Maison P, et al (2002) Focal nodular hyperplasia of the liver in men: is presentation the same in men and women? Gut 50: 877–80

    Article  CAS  PubMed  Google Scholar 

  10. Gastroenterology 97: 154–7

    CAS  PubMed  Google Scholar 

  11. Mathieu D, Kobeiter H, Maison P, et al (2000) Oral contraceptive use and focal nodular hyperplasia of the liver. Gastroenterology 118: 560–4

    Article  CAS  PubMed  Google Scholar 

  12. Nguyen BN, Flejou JF, Terris B, et al (1999) Focal nodular hyperplasia of the liver: a comprehensive pathological study of 305 lesions and recognition of new histologic forms. Am J Surg Pathol 23: 1441–54

    Article  CAS  PubMed  Google Scholar 

  13. Pain JA, Gimson AE, Williams R, et al (1991) Focal nodular hyperplasia of the liver: results of treatment and options on management. Gut 32: 524–7

    Article  CAS  PubMed  Google Scholar 

  14. Paradis V, Laurent A, Flejou JF, et al (1997) Evidence for the polyclonal nature of focal nodular hyperplasia of the liver by the study of X-chromosome inactivation. Hepatology 26: 891–5

    Article  CAS  PubMed  Google Scholar 

  15. Paradis V, Bièche I, Dargére D, et al (2003) A quantitative gene expression study suggests a role for angiopoietins in focal nodular hyperplasia. Gastroenterology 124: 651–9

    Article  PubMed  Google Scholar 

  16. Rebouissou S, Bioulac-Sage P, Zucman-Rossi J (2008) Molecular pathogenesis of focal nodular hyperplasia and hepatocellular adenoma. J Hepatol 48: 163–70

    Article  CAS  PubMed  Google Scholar 

  17. Reymond D, Plaschkes R, Lathy A, et al (1995) Focal nodular hyperplasia of the liver in children: review of follow-up and outcome. J Pediatr Surg 30: 1590–3

    Article  CAS  PubMed  Google Scholar 

  18. Scalori A, Tavani A, Gallus S, et al (2002) Risk factors for focal nodular hyperplasia of the liver: an Italian case-control study. Am J Gastroenterol 97: 2371–3

    Article  PubMed  Google Scholar 

  19. Wanless IR, Albrecht S, Bilbao J, et al (1989) Multiple focal hyperplasia of the liver associated with vascular malformations of various organs and neoplasia of the brain: a new syndrome. Mod Pathol 2: 456–62

    CAS  PubMed  Google Scholar 

  20. Weimann A, Ringe B, Klempnauer J, et al (1997) Benign liver tumors: differential diagnosis and indications for surgery. World J Surg 21: 983–90

    Article  CAS  PubMed  Google Scholar 

  21. Weimann A, Mossinger M, Fronhoff K, et al (1998) Pregnancy in women with observed focal nodular hyperplasia of the liver. Lancet 351: 1251–2

    Article  CAS  PubMed  Google Scholar 

  22. Whelan TJ, Baugh JH, Chandor S (1973) Focal nodular hyperplasia of the liver. Ann Surg 177: 150–8

    Article  PubMed  Google Scholar 

References

  1. Albores-Saavedra J, Hoang MP, Murakata LA, et al (2001) Atypical bile duct adenoma, clear cell type: a previously undescribed tumor of the liver. Am J Surg Pathol 25: 956–60

    Article  CAS  PubMed  Google Scholar 

  2. Allaire GS, Rabin L, Ishak KG, et al (1988) Bile duct adenoma. A study of 152 cases. Am J Surg Pathol 12: 708–15

    Article  CAS  PubMed  Google Scholar 

  3. Bhathal PS, Hughes NR, Goodman ZD (1996) The so-called bile duct adenoma is a peribiliary gland hamartoma. Am J Surg Pathol 20: 858–64

    Article  CAS  PubMed  Google Scholar 

  4. Dumas A, Thung SN, Lin CS (1998) Diffuse hyperplasia of the peribiliary glands. Arch Pathol Lab Med 122: 87–9

    CAS  PubMed  Google Scholar 

  5. Wanless IR (2002) Benign liver tumors. Clin Liver Dis 6: 513–26

    Article  PubMed  Google Scholar 

References

  1. Devaney K, Goodman ZD, Ishak KG (1994) Hepatobiliary cystadenoma and cystadenocarcinoma. A light microscopic and immunohistochemical study of 70 patients. Am J Surg Pathol 18: 1078–91

    Article  CAS  PubMed  Google Scholar 

  2. Ishak KG, Willis GW, Cummis SD, et al (1977) Biliary cys-tadenoma and cystadenocarcinoma: report of 14 cases and review of the literature. Cancer 29: 322–38

    Article  Google Scholar 

  3. Regev A, Reddy KR, Berho M, et al (2001) Large cystic lesions of the liver in adults: a 15 year experience in a tertiary center. J Am Coll Surg 193: 36–45

    Article  CAS  PubMed  Google Scholar 

  4. Siebenkotten V, Wennig M, Malms J, et al (1999) Ein zys-tischer echinokokkenähnlicher Lebertumor. Z Gastroenterol 37: 379–83

    CAS  PubMed  Google Scholar 

  5. Sutton CD, White SA, Berry DP, et al (2000) Intrahepatic biliary cystadenoma causing luminal common bile duct obstruction. Dig Surg 17: 297–9

    Article  CAS  PubMed  Google Scholar 

  6. Thomas JA, Scriven MW, Puntis MC, et al (1992) Elevated serum Ca 19–9 levels in hepatobiliary cystadenoma with mesenchymal stroma. Two case reports with immunohis-tochemical confirmation. Cancer 70: 1841–46

    Article  CAS  PubMed  Google Scholar 

  7. Woods GL (1981) Biliary cystadenocarcinoma. Case report of hepatic malignancy originating in benign cystadenoma. Cancer 47: 2936–40

    Article  CAS  PubMed  Google Scholar 

References

  1. Amaya S, Sasaki M, Watanabe Y, et al (2001) Expression of MUC1 and MUC2 and carbohydrate antigen Tn change during malignant transformation of biliary papillomatosis. Histopathology 38: 550–60

    Article  CAS  PubMed  Google Scholar 

  2. Beavers KL, Fried MW, Johnson MW, et al (2001) Orthotopic liver transplantation for biliary papillomatosis. Liver Transpl 7: 264–5

    Article  CAS  PubMed  Google Scholar 

  3. Gunven P, Gorsetman J, Ohlsen H, et al (2000) Six-year recurrence free survival after intraluminal iridium-192 therapy for human bilobar biliary papillomatosis. Cancer 89: 69–73

    Article  CAS  PubMed  Google Scholar 

  4. Kim YS, Myung SI, Kim SY, et al (1998) Biliary papilloma-tosis: clinical, cholangiographic and cholangioscopic find-ings. Endoscopy 30: 763–67

    Article  CAS  PubMed  Google Scholar 

  5. Kim JD, Lee KM, Chung WC, et al (2007) Acute pancreatitis and cholangitis caused by hemobilia from biliary papil-lomatosis. Gastrointest Endosc 65: 177–80

    Article  PubMed  Google Scholar 

  6. Lee SS, Kim MH, Lee SK, et al (2004) Clinicopathologic review of 58 patients with biliary papillomatosis. Cancer 100: 783–93

    Article  PubMed  Google Scholar 

  7. Mercadier M, Bodard M, Fingerhut A, et al (1984) Papillomatosis of the intrahepatic bile ducts. World J Surg 8: 30–5

    Article  CAS  PubMed  Google Scholar 

  8. Vassiliou I, Kairi-Vassilatou E, Marinis A, et al (2006) Malignant potential of intrahepatic biliary papillomatosis: a case report and review of the literature. World J Surg Oncol. 4: 71

    Article  PubMed  Google Scholar 

  9. Wang YJ, Lee SD, Lai KH, et al (1993) Primary biliary cystic tumors of the liver. Am J Gastroenterol 88: 599–603

    CAS  PubMed  Google Scholar 

References

  1. Adams YG, Hunos AG, Fortnes JG (1970) Giant haeman-giomas of the liver. Ann Surg 172: 239–45

    Article  Google Scholar 

  2. Dehner LP, Ishak KG (1971) Vascular tumors of the liver in infants and children. Arch Pathol 92: 101–11

    CAS  PubMed  Google Scholar 

  3. Dietrich CF, Mertens JC, Braden B, et al (2007) Contrast-enhanced ultrasound of histologically proven liver heman-giomas. Hepatology 45: 1139–45

    Article  PubMed  Google Scholar 

  4. GandolfiL, Leo P, Solmi L, et al (1991) Natural history of hepatic haemangiomas: clinical and ultrasound study. Gut 32: 677–80

    Article  CAS  PubMed  Google Scholar 

  5. Gibney RG, Hendin AP, Cooperberg PL (1987) Sonographically detected hepatic haemangiomas: absence of change over time. Am J Roentgenol 149: 953–7

    CAS  Google Scholar 

  6. Glinkova V, Shevah O, Boaz M, et al (2004) Hepatic hae-mangiomas: possible association with female sex hormones. Gut 53: 1352–5

    Article  CAS  PubMed  Google Scholar 

  7. Hobbs KEF (1990) Hepatic haemangiomas. World J Surg 14: 468–71

    Article  CAS  PubMed  Google Scholar 

  8. Kim GE, Thung SN, Tsui WM, et al (2006) Hepatic cavernous hemangioma: underrecognized associated histologic features. Liver Int 26: 334–8

    Article  PubMed  Google Scholar 

  9. Mortele KJ, Ros PR (2002) Benign liver neoplasms. Clin Liver Dis 6: 119–145

    Article  PubMed  Google Scholar 

  10. Riesener KP, Treutner KH, Treumann T, et al (1990) Das Leberhämangiom. Teil I. Diagnostik, Spontanverlauf, Komplikationen. Leber Magen Darm 20: 218–23

    CAS  PubMed  Google Scholar 

  11. Sugimura H, Tange T, Yamaguchi K, et al (1986) Systemic haemangiomatosis. Acta Pathol Jpn 36: 1089–98

    CAS  PubMed  Google Scholar 

  12. Wanless IR, Gryfe A (1986) Nodular transformation of the liver in hereditary hemorrhagic telangiectasia. Arch Pathol Lab Med 110: 331–5

    CAS  PubMed  Google Scholar 

References

  1. Biecker E, Fischer HP, Strunk H, et al (2003) Benign hepatic tumors. Z Gastroenterol 41: 191–200

    Article  CAS  PubMed  Google Scholar 

  2. Daller JA, Bueno J, Gutierrez J, et al (1999) Hepatic heman-gioendothelioma: clinical experience and management strategy. J Pediatr Surg 34: 98–105

    Article  CAS  PubMed  Google Scholar 

  3. Dehner LP, Ishak KG (1971) Vascular tumors of the liver in infants and children: a study of 30 cases and review of the literature. Arch Pathol 92: 101–11

    CAS  PubMed  Google Scholar 

  4. Ezekowitz RA, Mulliken JB, Folkman J (1992) Interferon alfa-2a therapy for life threatening hemangiomas of infancy. N Engl J Med 326: 1456–63

    Article  CAS  PubMed  Google Scholar 

  5. Guven A, Aygun C, Ince H, et al (2005) Severe hypothyroid-ism caused by hepatic hemangioendothelioma in an infant of a diabetic mother. Horm Res 63: 86–9

    Article  PubMed  CAS  Google Scholar 

  6. Hurvitz SA, Hurvitz CH, Sloninsky L, et al (2000) Successful treatment with cyclophosphamide of life-threatening diffuse hemangiomatosis involving the liver. J Pediatr Hematol Oncol 22: 527–32

    Article  CAS  PubMed  Google Scholar 

  7. Laird WP, Friedman S, Koop CE, et al (1976) Hepatic hae-mangiomatosis. Successful management by hepatic artery ligation. Am J Dis Child 130: 657–9

    CAS  PubMed  Google Scholar 

  8. Lee TC, Barshes NR, Agee EE, et al (2006) Resolution of medically resistant hypothyroidism after liver transplantation for hepatic hemangioendothelioma. J Pediatr Surg 41: 1783–5

    Article  PubMed  Google Scholar 

  9. Mortele KJ, Ros PR (2002) Benign liver neoplasmas. Clin Liver Dis 6: 119–45

    Article  PubMed  Google Scholar 

  10. Sari N, Yalcin B, Akyuz C, et al (2006) Infantile hepatic hemangioendothelioma with elevated serum alpha-fetoprotein. Pediatr Hematol Oncol 23: 639–47

    Article  PubMed  Google Scholar 

  11. Selby DM, Stocker JT, Ishak KG (1992) Angiosarcoma of the liver in childhood. A clinicopathologic and follow-up study of 10 cases. Pediatr Pathol 12: 485–9

    Article  CAS  PubMed  Google Scholar 

  12. Selby DM, Stocker JT, Waclawiw MA, et al (1994) Infantile hemangioendothelioma of the liver. Hepatology 20: 39–45

    CAS  PubMed  Google Scholar 

  13. Stanley P, Geer GD, Miller JH, et al (1989) Infantile hepatic haemangiomas. Cancer 64: 936–49

    Article  CAS  PubMed  Google Scholar 

  14. Walsh R, Harrington J, Beneck D, et al (2004) Congenital infantile hepatic hemangioendothelioma type II treated with orthotopic liver transplantation. J Pediatr Hematol Oncol 26: 121–3

    Article  PubMed  Google Scholar 

References

  1. Chan SC, Huang SF, Lee WC, et al (2005) Solitary hepatic lymphangioma–a case report. Int J Clin Pract Suppl 147: 100–2

    PubMed  Google Scholar 

  2. Damascelli B, Spagnoli I, Garbagnati F, et al (1984) Massive lymphorrhoea after fine needle biopsy of the cystic haemo-lymphangioma of the liver. Eur J Radiol 4: 107–9

    CAS  PubMed  Google Scholar 

  3. Datz C, Graziadei IW, Dietze O, et al (2001) Massive progression of diffuse hepatic lymphangiomatosis after liver resection and rapid deterioration after liver transplantation. Am J Gastroenterol 96: 1278–81

    Article  CAS  PubMed  Google Scholar 

  4. O'Sullivan DA, Torres VE, de Groen PC, et al (1998) Hepatic lymphangiomatosis mimicking polycystic liver disease. Mayo Clin Proc 73: 1188–92

    Article  PubMed  Google Scholar 

  5. Van Steenbergen W, Joosten E, Marchal G, et al (1985) Hepatic lymphangiomatosis. Report of a case and review of the literature. Gastroenterology 88: 1968–72

    PubMed  Google Scholar 

References

  1. Arfa MN, Gharbi L, Zaafrani MR, et al (2003) Cystic mes-enchymal hamartoma of the liver report of a case and review of the literature. Hepatogastroenterology 50(Suppl 2): ccxlix–ccli

    PubMed  Google Scholar 

  2. Horton KM, Bluemke DA, Hruban RH, et al (1999) CT and MR imaging of benign hepatic and biliary tumors. Radiographics 19: 431–51

    CAS  PubMed  Google Scholar 

  3. Ros PR, Goodman ZD, Ishak KG, et al (1986) Mesenchymal hamartoma of the liver: radiologic-pathologic correlation. Radiology 158: 619–24

    CAS  PubMed  Google Scholar 

References

  1. Ahmadi T, Itai Y, Takahashi M, et al (1998) Angiomyolipoma of the liver: significance of CT and MR dynamic study. Abdom Imaging 23: 520–6

    Article  CAS  PubMed  Google Scholar 

  2. Basaran C, Karcaaltincaba M, Akata D, et al (2005) Fat-containing lesions of the liver: cross-sectional imaging find-ings with emphasis on MRI. AJR Am J Roentgenol 184: 1103–10

    PubMed  Google Scholar 

  3. Chang YC, Tsai HM, Chow NH (2001) Hepatic angiomyo-lipoma with concomitant hepatocellular carcinomas. Hepatogastroenterology 48: 253–5

    CAS  PubMed  Google Scholar 

  4. Dalle I, Sciot R, de Vo s R, et al (2000) Malignant angiomyo-lipoma of the liver: a hitherto unreported variant. Histopathology 36: 443–50

    Article  CAS  PubMed  Google Scholar 

  5. Fetsch PA, Fetsch JF, Marincola FM, et al (1998) Comparison of melanoma antigen recognized by T cells (MART-1) to HMB-45: additional evidence to support a common lineage for angiomyolipoma, lymphangiomyomatosis, and clear cell sugar tumor. Mod Pathol 11: 699–703

    CAS  PubMed  Google Scholar 

  6. Fricke BL, Donnelly LF, Casper KA, et al (2004) Frequency and imaging appearance of hepatic angiomyolipomas in pediatric and adult patients with tuberous sclerosis. AJR Am J Roentgenol 182: 1027–30

    PubMed  Google Scholar 

  7. Fukukura Y, Fujuyoshi F, Inoue H, et al (2000) Focal fatty infiltration in the posterior aspect of hepatic segment IV: relationship to pancreaticoduodenal venous drainage. Am J Gastroenterol 95: 3590–5

    Article  CAS  PubMed  Google Scholar 

  8. Goodman ZD, Ishak KG (1994) Angiomyolipomas of the liver. Am J Surg Pathol 8: 745–50

    Google Scholar 

  9. Guidi G, Catalano O, Rotondo A (1997) Spontaneous rupture of a hepatic angiomyolipoma: CT findings and literature review. Eur Radiol 7: 335–7

    Article  CAS  PubMed  Google Scholar 

  10. Intern Med 38: 345–8

    Article  CAS  PubMed  Google Scholar 

  11. Horton KM, Bluemke DA, Hruban RH, et al (1999) CT and MR imaging of benign hepatic and biliary tumors. Radiographics 19: 431–51

    CAS  PubMed  Google Scholar 

  12. Kannangai R, Diehl AM, Sicklick J, et al (2005) Hepatic angiomyolipoma and hepatic stellate cells share a similar gene expression profile. Hum Pathol 36: 341–7

    Article  CAS  PubMed  Google Scholar 

  13. Karhunen PJ (1985) Hepatic pseudolipoma. J Clin Pathol. 38: 877–9

    Article  CAS  PubMed  Google Scholar 

  14. Kelleher T, Staunton M, Malone D, et al (2004) Budd Chiari syndrome associated with angiomyolipoma of the liver. J Hepatol 40: 1048–9

    Article  PubMed  Google Scholar 

  15. Langner C, Homayounfar K, B. Ruten, et al (2001) Gleichzeitiges Auftreten von Angiomyolipom, fokaler nod-ulärer Hyperplasie, cholangiozellulärem Adenom und Hämangiom in der Leber. Pathologe 22: 417–23

    Article  CAS  PubMed  Google Scholar 

  16. Makhlouf HR, Remotti HE, Ishak KG (2002) Expression of KIT (CD117) in angiomyolipoma. Am J Surg Pathol 26: 493–7

    Article  PubMed  Google Scholar 

  17. McKinney CA, Geiger JD, Castle VP, et al (2005) Aggressive hepatic angiomyolipoma in a child. Pediatr Hematol Oncol 22: 17–24

    Article  PubMed  Google Scholar 

  18. Nonomura A, Mizukami Y, Kadoya M (1994) Angiomyolipoma of the liver. A collective review. J Gastroenterol 29: 95–105

    Article  CAS  PubMed  Google Scholar 

  19. Nonomura A, Minato H, Kurumaya H (1998) Angiomyolipoma predominantly composed of smooth muscle cells: problems in histological diagnosis. Histopathology 33: 20–7

    Article  CAS  PubMed  Google Scholar 

  20. Nonomura A, Enomoto Y, Takeda M, et al (2006) Invasive growth of hepatic angiomyolipoma; a hitherto unreported ominous histological feature. Histopathology 48: 831–5

    Article  CAS  PubMed  Google Scholar 

  21. Prasad SR, Wang H, Rosas H, et al (2005) Fat-containing lesions of the liver: radiologic-pathologic correlation. Radiographics 25: 321–31

    Article  PubMed  Google Scholar 

  22. Ren N, Qin LX, Tang Z Y, et al (2003) Diagnosis and treatment of hepatic angiomyolipoma in 26 cases. World J Gastroenterol 9: 1856–8

    PubMed  Google Scholar 

  23. Szekely E, Schaff Z, Madaras L, et al (2000) Trabecular angiomyolipoma mimicking hepatic cell carcinoma. Pathol Oncol Res 6: 224–6

    Article  CAS  PubMed  Google Scholar 

  24. Wang SN, Tsai KB, Lee KT (2006) Hepatic angiomyoli-poma with trace amounts of fat: a case report and literature review. J Clin Pathol 59: 1196–9

    Article  PubMed  Google Scholar 

  25. Xu AM, Zhang SH, Zheng JM, et al (2006) Pathological and molecular analysis of sporadic hepatic angiomyolipoma. Hum Pathol 37: 735–41

    Article  CAS  PubMed  Google Scholar 

  26. Yeh CN, Chen MF, Hung CF, et al (2001) Angiomyolipoma of the liver. J Surg Oncol 77: 195–200

    Article  CAS  PubMed  Google Scholar 

  27. Zheng RQ, Kudo M (2005) Hepatic angiomyolipoma: iden-tification of an efferent vessel to be hepatic vein by contrast-enhanced harmonic ultrasound. Br J Radiol 78: 956–60

    Article  CAS  PubMed  Google Scholar 

References

  1. Bernard M, Marie I, Riachi G, et al (2005) Inflamm atory pseudotumor of the liver revealing gynecological Corynebacterium infection. Scand J Gastroenterol 40: 875–7

    Article  PubMed  Google Scholar 

  2. Biecker E, Zimmermann A, Dufour JF (2003) Spontaneous regression of an inflammatory pseudotumor of the liver. Z Gastroenterol 41: 991–4

    Article  CAS  PubMed  Google Scholar 

  3. Czauderna P, Sznurkowska K, Korzon M, et al (1999) Association of inflammatory pseudotumor of the liver and Papillon-Lefevre syndrome — case report. Eur J Pediatr Surg 9: 343–6

    Article  CAS  PubMed  Google Scholar 

  4. Colakoglu O, Unsal B, Haciyanli M, et al (2005) A successfully managed inflammatory pseudotumour of liver without surgery: report of a case. Acta Gastroenterol Belg 68: 382–4

    PubMed  Google Scholar 

  5. Kanno A, Satoh K, Kimura K, et al (2005) Autoimmune pancreatitis with hepatic inflammatory pseudotumor. Pancreas 31: 420–3

    Article  PubMed  Google Scholar 

  6. Kawamura E, Habu D, Tsushima H, et al (2006) A case of hepatic inflammatory pseudotumor identified by FDG-PET. Ann Nucl Med 20: 321–3

    Article  PubMed  Google Scholar 

  7. Koide H, Sato K, Fukusato T, et al (2006) Spontaneous regression of hepatic inflammatory pseudotumor with primary biliary cirrhosis: case report and literature review. World J Gastroenterol 14: 1645–8

    Google Scholar 

  8. Moran CA, Ishak KG, Goodman ZD (1998) Solitary fibrous tumor of the liver: a clinicopathologic and immunohis-tochemical study of nine cases. Ann Diagn Pathol 2: 1–7

    PubMed  Google Scholar 

  9. Nishimura R, Teramoto N, Tanada M, et al (2005) Inflammatory pseudotumor of the liver associated with malignant disease: report of two cases and a review of the literature. Virchows Arch 447: 660–4

    Article  PubMed  Google Scholar 

  10. Ogawa T, Yokoi H, Kawarada Y (1998) A case of inflamma-tory pseudotumor of the liver causing elevated serum CA19–9 levels. Am J Gastroenterol 93: 2551–5

    Article  CAS  PubMed  Google Scholar 

  11. Pack GT, Baker HW (1953) Total right hepatic lobectomy. Report of a case. Ann Surg 138: 253–8

    Article  CAS  PubMed  Google Scholar 

  12. Pecorella I, Ciardi A, Memeo L, et al (1999) Inflammatory pseudotumor of the liver–evidence for malignant transformation. Pathol Res Pract 195: 115–20

    CAS  PubMed  Google Scholar 

  13. Sakai T, Shiraki K, Yamamoto N, et al (2002) Diagnosis of inflammatory pseudotumor of the liver. Int J Mol Med 10: 281–5

    PubMed  Google Scholar 

  14. Sasahira N, Kawabe T, Nakamura A, et al (2005) Inflammatory pseudotumor of the liver and peripheral eosinophilia in autoimmune pancreatitis. World J Gastroenterol 11: 922–5

    PubMed  Google Scholar 

  15. Schmid A, Janig D, Bohuszlavizki A, et al (1996) Inflammatory pseudotumor of the liver presenting as inci-dentaloma: report of a case and review of the literature. Hepatogastroenterology 43: 1009–14

    CAS  PubMed  Google Scholar 

  16. Shek TWH, Ng IOL, Chan KW (1993) Inflammatory pseudotumor of the liver. Report of four cases and review of the literature. Am J Surg Pathol 17: 231–8

    Article  CAS  PubMed  Google Scholar 

  17. Someren A (1978) “Inflammatory pseudotumor” of the liver with occlusive phlebitis. Am J Clin Pathol 69: 176–81

    CAS  PubMed  Google Scholar 

  18. Strohm WD, Stähle KS, Schlumm G (1996) Inflammatorischer Pseudotumor der Leber. Fallbericht über die seltene Differenzialdiagnose des hepatozellulären Karzinoms. Z Gastoenterol 34: 132–7

    CAS  Google Scholar 

  19. Toda K, Yasuda I, Nishigaki Y, et al (2003) Inflammatory pseudotumor of the liver with primary sclerosing cholangi-tis. J Gastroenterol35: 304–9

    Google Scholar 

  20. Tublin ME, Moser AJ, Marsh JW, et al (2007) Biliary inflam-matory pseudotumor: imaging features in seven patients. AJR Am J Roentgenol 188: W44–8

    Article  PubMed  Google Scholar 

  21. White JE, Chase CW, Kelley JE, et al (1997) Inflammatory pseudotumor of the liver associated with extrahepatic infection. South Med J 90: 23–9

    CAS  PubMed  Google Scholar 

  22. Yoon KH, Ha HK, Lee JS, et al (1999) Inflammatory pseudo-tumor of the liver in patients with recurrent pyogenic cholan-gitis: CT-histopathologic correlation. Radiology 211: 373–9

    CAS  PubMed  Google Scholar 

  23. Zamir D, Jarchowsky J, Singer C, et al (1998) Inflammatory pseudotumor of the liver — a rare entity and a diagnostic challenge. Am J Gastroenterol 93: 1538–40

    CAS  PubMed  Google Scholar 

  24. Zavaglia C, Barberis M, Gelosa F, et al (1996) Inflammatory pseudotumor of the liver with malignant transformation. Report of two cases. Ital J Gastroenterol 28: 152–9

    CAS  PubMed  Google Scholar 

  25. Zen Y, Harada K, Sasaki M, et al (2004) IgG4-related scle-rosing cholangitis with and without hepatic inflammatory pseudotumor, and sclerosing pancreatitis-associated scleros-ing cholangitis: do they belong to a spectrum of sclerosing pancreatitis? Am J Surg Pathol 28: 1193–203

    Article  PubMed  Google Scholar 

References

  1. Bioulac-Sage P, Laumonier H, Laurent C, et al (2008) Benign an malignant vascular tumors of the liver in adults. Semin Liver Dis 28: 302–14

    Article  PubMed  Google Scholar 

  2. Kaiserling E, Müller H (2005) Neoplasm of hepatic stellate cells (spongiotic pericytoma): a new tumor entity in human liver. Pathol Res Pract 201: 733–43

    Article  CAS  PubMed  Google Scholar 

  3. Mesenas SJ, Ng KY, Raj P, et al (2000) Primary leiomyoma of the liver. Singapore Med J 41: 129–31

    CAS  PubMed  Google Scholar 

  4. Sclabas GM, Maurer CA, Wente MN, et al (2002) Case report: hepatic leiomyoma in a renal transplant recipient. Transplant Proc 34: 3200–2

    Article  CAS  PubMed  Google Scholar 

  5. Wang MH, Wu CT, Hung CC, et al (2000) Hepatic leiomyo-matous neoplasm associated with Epstein Barr virus infection in an adult with acquired immunodeficiency syndrome. J Formos Med Assoc 99: 873–5

    CAS  PubMed  Google Scholar 

  6. Yoon GS, Kang GH, Kim OJ (1998) Primary myxoid leio-myoma of the liver. Arch Pathol Lab Med 122: 1112–5

    CAS  PubMed  Google Scholar 

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Dancygier, H. (2010). Benign Tumors. In: Clinical Hepatology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-04519-6_47

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