Skip to main content

Physical Activity and Lung Cancer Prevention

Part of the Recent Results in Cancer Research book series (RECENTCANCER,volume 186)

Abstract

Since lung cancer is among the cancers with the highest incidence and has the highest mortality rate of cancer worldwide, the means of reducing its impact are urgently needed. Emerging evidence shows that physical activity plays an etiological role in lung cancer risk reduction. The majority of studies support the fact that total and recreational physical activity reduces lung cancer risk by 20–30% for women and 20–50% for men, and there is evidence of a dose–response effect. The biological mechanisms operating between physical activity and lung cancer are likely complex and influenced by many factors including inherited or acquired susceptibility genes, gender, smoking, and other environmental factors. Several plausible biological factors and mechanisms have been hypothesized linking physical activity to reduced lung cancer risk including: improved pulmonary function, reduced concentrations of carcinogenic agents in the lungs, enhanced immune function, reduced inflammation, enhanced DNA repair capacity, changes in growth factor levels and possible gene–physical activity interactions. Future research should target the possible subgroup effects and the biologic mechanisms that may be involved.

Keywords

  • Physical Activity
  • Lung Cancer
  • Lung Cancer Risk
  • Total Physical Activity
  • Large Cell Carcinoma

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

This is a preview of subscription content, access via your institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • DOI: 10.1007/978-3-642-04231-7_5
  • Chapter length: 33 pages
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
eBook
USD   229.00
Price excludes VAT (USA)
  • ISBN: 978-3-642-04231-7
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book
USD   299.00
Price excludes VAT (USA)
Hardcover Book
USD   299.00
Price excludes VAT (USA)
Fig. 5.1
Fig. 5.2
Fig. 5.3
Fig. 5.4
Fig. 5.5

References

  • Ahn J, Weinstein SJ, Snyder K, Pollak MN, Virtamo J, Albanes D (2006) No association between serum insulin-like growth factor (IGF)-I, IGF-binding protein-3, and lung cancer risk. Cancer Epidemiol Biomarkers Prev 15:2010–2012

    PubMed  CrossRef  CAS  Google Scholar 

  • Albanes D, Blair A, Taylor PR (1989) Physical activity and risk of cancer in the NHANES I population. Am J Public Health 79:744–750

    PubMed  CrossRef  CAS  Google Scholar 

  • Alberg AJ, Ford JG, Samet JM (2007) Epidemiology of lung cancer: ACCP evidence-based clinical practice guidelines, 2nd edn. Chest 132: 29S–55S

    PubMed  CrossRef  CAS  Google Scholar 

  • Alfano CM, Klesges RC, Murray DM, Bowen DJ, McTiernan A, Vander Weg MW, Robinson LA, Cartmel B, Thornquist MD, Barnett M, Goodman GE, Omenn GS (2004) Physical activity in relation to all-site and lung cancer incidence and mortality in current and former smokers. Cancer Epidemiol Biomarkers Prev 13:2233–2241

    PubMed  Google Scholar 

  • American Cancer Society (2009) Cancer Facts & Figures 2009. American Cancer Society, Atlanta

    Google Scholar 

  • Amos CI, Xu W, Spitz MR (1999) Is there a genetic basis for lung cancer susceptibility? Recent Results Cancer Res 151:3–12

    PubMed  CrossRef  CAS  Google Scholar 

  • Amos CI, Wu X, Broderick P, Gorlov IP, Gu J, Eisen T, Dong Q, Zhang Q, Gu X, Vijayakrishnan J, Sullivan K, Matakidou A, Wang Y, Mills G, Doheny K, Tsai YY, Chen WV, Shete S, Spitz MR, Houlston RS (2008) Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. Nat Genet 40:616–622

    PubMed  CrossRef  CAS  Google Scholar 

  • Asami S, Manabe H, Miyake J, Tsurudome Y, Hirano T, Yamaguchi R, Itoh H, Kasai H (1997) Cigarette smoking induces an increase in oxidative DNA damage, 8-hydroxydeoxyguanosine, in a central site of the human lung. Carcinogenesis 18:1763–1766

    PubMed  CrossRef  CAS  Google Scholar 

  • Bak H, Christensen J, Thomsen BL, Tjonneland A, Overvad K, Loft S, Raaschou-Nielsen O (2005) Physical activity and risk for lung cancer in a Danish cohort. Int J Cancer 116:439–444

    PubMed  CrossRef  CAS  Google Scholar 

  • Ballaz S, Mulshine JL (2003) The potential contributions of chronic inflammation to lung carcinogenesis. Clin Lung Cancer 5:46–62

    PubMed  CrossRef  CAS  Google Scholar 

  • Blair SN, Powell KE, Bazzarre TL, Early JL, Epstein LH, Green LW, Harris SS, Haskell WL, King AC, Koplan J et al. (1993) Physical inactivity. Workshop V. AHA Prevention Conference III. Behavior change and compliance: keys to improving cardiovascular health. Circulation 88:1402–1405

    Google Scholar 

  • Bouchard C (2001) Physical activity and health: introduction to the dose-response symposium. Med Sci Sports Exerc 33:S347–S350

    PubMed  CrossRef  CAS  Google Scholar 

  • Brownson RC, Chang JC, Davis JR, Smith CA (1991) Physical activity on the job and cancer in Missouri. Am J Public Health 81:639–642

    PubMed  CrossRef  CAS  Google Scholar 

  • Bruske-Hohlfeld I (2009) Environmental and occupational risk factors for lung cancer. Methods Mol Biol 472:3–23

    PubMed  CrossRef  Google Scholar 

  • Bruunsgaard H (2005) Physical activity and modulation of systemic low-level inflammation. J Leukoc Biol 78:819–835

    PubMed  CrossRef  CAS  Google Scholar 

  • Cheng YJ, Macera CA, Addy CL, Sy FS, Wieland D, Blair SN (2003) Effects of physical activity on exercise tests and respiratory function. Br J Sports Med 37:521–528

    PubMed  CrossRef  CAS  Google Scholar 

  • Colbert LH, Hartman TJ, Tangrea JA, Pietinen P, Virtamo J, Taylor PR, Albanes D (2002) Physical activity and lung cancer risk in male smokers. Int J Cancer 98:770–773

    PubMed  CrossRef  CAS  Google Scholar 

  • DeVita VT, Lawrence TS, Rosenberg SA (2008) DeVita, Hellman, and Rosenberg’s cancer: principles & practice of oncology. Philadel-phia, PA

    Google Scholar 

  • Dosemeci M, Hayes RB, Vetter R, Hoover RN, Tucker M, Engin K, Unsal M, Blair A (1993) Occupational physical activity, socioeconomic status, and risks of 15 cancer sites in Turkey. Cancer Cause Control 4:313–321

    CrossRef  CAS  Google Scholar 

  • Elosua R, Molina L, Fito M, Arquer A, Sanchez-Quesada JL, Covas MI, Ordonez-Llanos J, Marrugat J (2003) Response of oxidative stress biomarkers to a 16-week aerobic physical activity program, and to acute physical activity, in healthy young men and women. Atherosclerosis 167:327–334

    PubMed  CrossRef  CAS  Google Scholar 

  • Engels EA (2008) Inflammation in the development of lung cancer: epidemiological evidence. Expert Rev Anticancer Ther 8:605–615

    PubMed  CrossRef  CAS  Google Scholar 

  • Fairey AS, Courneya KS, Field CJ, Bell GJ, Jones LW, Mackey JR (2005) Randomized controlled trial of exercise and blood immune function in postmenopausal breast cancer survivors. J Appl Physiol 98:1534–1540

    PubMed  CrossRef  Google Scholar 

  • Ferlay J, Autier P, Boniol M, Heanue M, Colombet M, Boyle P (2007) Estimates of the cancer incidence and mortality in Europe in 2006. Ann Oncol 18:581–592

    PubMed  CrossRef  CAS  Google Scholar 

  • Ford ES (2002) Does exercise reduce inflammation? Physical activity and C-reactive protein among U.S. adults. Epidemiology 13:561–568

    PubMed  CrossRef  Google Scholar 

  • Friedenreich CM, Orenstein MR (2002) Physical activity and cancer prevention: etiologic evidence and biological mechanisms. J Nutr 132:3456S–3464S

    PubMed  CAS  Google Scholar 

  • Hung RJ, McKay JD, Gaborieau V, Boffetta P, Hashibe M, Zaridze D, Mukeria A, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Mates D, Bencko V, Foretova L, Janout V, Chen C, Goodman G, Field JK, Liloglou T, Xinarianos G, Cassidy A, McLaughlin J, Liu G, Narod S, Krokan HE, Skorpen F, Elvestad MB, Hveem K, Vatten L, Linseisen J, Clavel-Chapelon F, Vineis P, Bueno-de-Mesquita HB, Lund E, Martinez C, Bingham S, Rasmuson T, Hainaut P, Riboli E, Ahrens W, Benhamou S, Lagiou P, Trichopoulos D, Holcatova I, Merletti F, Kjaerheim K, Agudo A, Macfarlane G, Talamini R, Simonato L, Lowry R, Conway DI, Znaor A, Healy C, Zelenika D, Boland A, Delepine M, Foglio M, Lechner D, Matsuda F, Blanche H, Gut I, Heath S, Lathrop M, Brennan P (2008) A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature 452:633–637

    PubMed  CrossRef  CAS  Google Scholar 

  • IARC (2002) Weight control and physical activity. International Agency for Research on Cancer, Lyon

    Google Scholar 

  • Inoue M, Yamamoto S, Kurahashi N, Iwasaki M, Sasazuki S, Tsugane S (2008) Daily total physical activity level and total cancer risk in men and women: results from a large-scale population-based cohort study in Japan. Am J Epidemiol 168:391–403

    PubMed  CrossRef  Google Scholar 

  • Jakes RW, Day NE, Patel B, Khaw KT, Oakes S, Luben R, Welch A, Bingham S, Wareham NJ (2002) Physical inactivity is associated with lower forced expiratory volume in 1 second: European prospective investigation into cancer-norfolk prospective population study. Am J Epidemiol 156:139–147

    PubMed  CrossRef  Google Scholar 

  • Jakobisiak M, Lasek W, Golab J (2003) Natural mechanisms protecting against cancer. Immunol Lett 90:103–122

    PubMed  CrossRef  CAS  Google Scholar 

  • Jemal A, Travis WD, Tarone RE, Travis L, Devesa SS (2003) Lung cancer rates convergence in young men and women in the United States: analysis by birth cohort and histologic type. Int J Cancer 105:101–107

    PubMed  CrossRef  CAS  Google Scholar 

  • Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ (2009) Cancer statistics, 2009. CA Cancer J Clin 59:225–249

    PubMed  CrossRef  Google Scholar 

  • Jones JI, Clemmons DR (1995) Insulin-like growth factors and their binding proteins: biological actions. Endocr Rev 16:3–34

    PubMed  CAS  Google Scholar 

  • Kasapis C, Thompson PD (2005) The effects of physical activity on serum C-reactive protein and inflammatory markers: a systematic review. J Am Coll Cardiol 45:1563–1569

    PubMed  CrossRef  CAS  Google Scholar 

  • Khuder SA (2001) Effect of cigarette smoking on major histological types of lung cancer: a meta-analysis. Lung Cancer 31:139–148

    PubMed  CrossRef  CAS  Google Scholar 

  • Knekt P, Raitasalo R, Heliovaara M, Lehtinen V, Pukkala E, Teppo L, Maatela J, Aromaa A (1996) Elevated lung cancer risk among persons with depressed mood. Am J Epidemiol 144: 1096–1103

    PubMed  CrossRef  CAS  Google Scholar 

  • Knuth AG, Hallal PC (2009) Temporal trends in physical activity: a systematic review. J Phys Act Health 6:548–559

    PubMed  Google Scholar 

  • Kubik A, Zatloukal P, Tomasek L, Pauk N, Petruzelka L, Plesko I (2004) Lung cancer risk among nonsmoking women in relation to diet and physical activity. Neoplasma 51: 136–143

    PubMed  CAS  Google Scholar 

  • Kubik A, Zatloukal P, Tomasek L, Pauk N, Havel L, Dolezal J, Plesko I (2007) Interactions between smoking and other exposures associated with lung cancer risk in women: diet and physical activity. Neoplasma 54:83–88

    PubMed  CAS  Google Scholar 

  • Kubik A, Zatloukal P, Tomasek L, Dolezal J, Syllabova L, Kara J, Kopecky P, Plesko I (2008) A case-control study of lifestyle and lung cancer associations by histological types. Neoplasma 55:192–199

    PubMed  CAS  Google Scholar 

  • Kubik AK, Zatloukal P, Tomasek L, Petruzelka L (2002) Lung cancer risk among Czech women: a case-control study. Prev Med 34:436–444

    PubMed  CrossRef  Google Scholar 

  • Landi MT, Chatterjee N, Yu K, Goldin LR, Goldstein AM, Rotunno M, Mirabello L, Jacobs K, Wheeler W, Yeager M, Bergen AW, Li Q, Consonni D, Pesatori AC, Wacholder S, Thun M, Diver R, Oken M, Virtamo J, Albanes D, Wang Z, Burdette L, Doheny KF, Pugh EW, Laurie C, Brennan P, Hung R, Gaborieau V, McKay JD, Lathrop M, McLaughlin J, Wang Y, Tsao MS, Spitz MR, Wang Y, Krokan H, Vatten L, Skorpen F, Arnesen E, Benhamou S, Bouchard C, Metsapalu A, Vooder T, Nelis M, Valk K, Field JK, Chen C, Goodman G, Sulem P, Thorleifsson G, Rafnar T, Eisen T, Sauter W, Rosenberger A, Bickeboller H, Risch A, Chang-Claude J, Wichmann HE, Stefansson K, Houlston R, Amos CI, Fraumeni JF Jr, Savage SA, Bertazzi PA, Tucker MA, Chanock S, Caporaso NE (2009) A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. Am J Hum Genet 85:679–691

    PubMed  CrossRef  CAS  Google Scholar 

  • Lee IM, Sesso HD, Paffenbarger RS Jr (1999) Physical activity and risk of lung cancer. Int J Epidemiol 28:620–625

    PubMed  CrossRef  CAS  Google Scholar 

  • Lee SY, Kim MT, Jee SH, Im JS (2002) Does hypertension increase mortality risk from lung cancer? A prospective cohort study on smoking, hypertension and lung cancer risk among Korean men. J Hypertens 20:617–622

    PubMed  CrossRef  CAS  Google Scholar 

  • Leitzmann MF, Koebnick C, Abnet CC, Freedman ND, Park Y, Hollenbeck A, Ballard-Barbash R, Schatzkin A (2009) Prospective study of physical activity and lung cancer by histologic type in current, former, and never smokers. Am J Epidemiol 169:542–553

    PubMed  CrossRef  Google Scholar 

  • London SJ, Yuan JM, Travlos GS, Gao YT, Wilson RE, Ross RK, Yu MC (2002) Insulin-like growth factor I, IGF-binding protein 3, and lung cancer risk in a prospective study of men in China. J Natl Cancer Inst 94:749–754

    PubMed  CrossRef  CAS  Google Scholar 

  • Lukanova A, Toniolo P, Akhmedkhanov A, Biessy C, Haley NJ, Shore RE, Riboli E, Rinaldi S, Kaaks R (2001) A prospective study of insulin-like growth factor-I, IGF-binding proteins-1, -2 and -3 and lung cancer risk in women. Int J Cancer 92:888–892

    PubMed  CrossRef  CAS  Google Scholar 

  • Mao Y, Pan S, Wen SW, Johnson KC (2003) Physical activity and the risk of lung cancer in Canada. Am J Epidemiol 158:564–575

    PubMed  CrossRef  Google Scholar 

  • McTiernan A (2008) Mechanisms linking physical activity with cancer. Nat Rev Cancer 8:205–211

    PubMed  CrossRef  CAS  Google Scholar 

  • Olson JE, Yang P, Schmitz K, Vierkant RA, Cerhan JR, Sellers TA (2002) Differential association of body mass index and fat distribution with three major histologic types of lung cancer: evidence from a cohort of older women. Am J Epidemiol 156:606–615

    PubMed  CrossRef  CAS  Google Scholar 

  • Parkin DM, Whelan SL, Ferlay J, Teppo L, Thomas DM (2006) Cancer incidence in five continents, vol. VIII. I S P N 155. International Agency for Research on Cancer, Lyon, France

    Google Scholar 

  • Pollak MN, Schernhammer ES, Hankinson SE (2004) Insulin-like growth factors and neoplasia. Nat Rev Cancer 4:505–518

    PubMed  CrossRef  CAS  Google Scholar 

  • Reid ME, Santella R, Ambrosone CB (2008) Molecular epidemiology to better predict lung cancer risk. Clin Lung Cancer 9:149–153

    PubMed  CrossRef  CAS  Google Scholar 

  • Renehan AG, Zwahlen M, Minder C, O’Dwyer ST, Shalet SM, Egger M (2004) Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis. Lancet 363:1346–1353

    PubMed  CrossRef  CAS  Google Scholar 

  • Rundle A (2005) Molecular epidemiology of physical activity and cancer. Cancer Epidemiol Biomarkers Prev 14:227–236

    PubMed  CrossRef  Google Scholar 

  • Rundle A, Richie J, Steindorf K, Peluso M, Overvad K, Raaschou-Nielsen O, Clavel-Chapelon F, Linseisen JP, Boeing H, Trichopoulou A, Palli D, Krogh V, Tumino R, Panico S, Bueno-De-Mesquita HB, Peeters PH, Lund E, Gonzalez CA, Martinez C, Dorronsoro M, Barricarte A, Tormo MJ, Quiros J, Agudo A, Berglund G, Jarvholm B, Bingham S, Key TJ, Gormally E, Saracci R, Kaaks R, Riboli E, Vineis P (2010) Physical activity and lung cancer among non-smokers: a pilot molecular epidemiological study within EPIC. Biomarkers 15:20–30

    PubMed  CrossRef  CAS  Google Scholar 

  • Sano H, Marugame T (2006) International comparisons of cumulative risk of lung cancer, from cancer incidence in five continents, vol VIII. Jpn J Clin Oncol 36:334–335

    PubMed  CrossRef  Google Scholar 

  • Schnohr P, Gronbaek M, Petersen L, Hein HO, Sorensen TI (2005) Physical activity in leisure-time and risk of cancer: 14-year follow-up of 28, 000 Danish men and women. Scand J Public Health 33:244–249

    PubMed  CrossRef  Google Scholar 

  • Schwartz AG, Prysak GM, Bock CH, Cote ML (2007) The molecular epidemiology of lung cancer. Carcinogenesis 28:507–518

    PubMed  CrossRef  CAS  Google Scholar 

  • Sellers TA, Potter JD, Folsom AR (1991) Association of incident lung cancer with family history of female reproductive cancers: the Iowa Women’s Health Study. Genet Epidemiol 8:199–208

    PubMed  CrossRef  CAS  Google Scholar 

  • Severson RK, Nomura AM, Grove JS, Stemmermann GN (1989) A prospective analysis of physical activity and cancer. Am J Epidemiol 130: 522–529

    PubMed  CAS  Google Scholar 

  • Shephard RJ, Shek PN (1995) Cancer, immune function, and physical activity. Can J Appl Physiol 20:1–25

    PubMed  CrossRef  CAS  Google Scholar 

  • Sin DD, Jones RL, Mannino DM, Paul Man SF (2004) Forced expiratory volume in 1 second and physical activity in the general population. Am J Med 117:270–273

    PubMed  CrossRef  Google Scholar 

  • Sinner P, Folsom AR, Harnack L, Eberly LE, Schmitz KH (2006) The association of physical activity with lung cancer incidence in a cohort of older women: the Iowa Women’s Health Study. Cancer Epidemiol Biomarkers Prev 15: 2359–2363

    PubMed  CrossRef  Google Scholar 

  • Sprague BL, Trentham-Dietz A, Klein BE, Klein R, Cruickshanks KJ, Lee KE, Hampton JM (2008) Physical activity, white blood cell count, and lung cancer risk in a prospective cohort study. Cancer Epidemiol Biomarkers Prev 17: 2714–2722

    PubMed  CrossRef  Google Scholar 

  • Steenland K, Nowlin S, Palu S (1995) Cancer incidence in the National Health and Nutrition Survey I. Follow-up data: diabetes, cholesterol, pulse and physical activity. Cancer Epidemiol Biomarkers Prev 4:807–811

    PubMed  CAS  Google Scholar 

  • Steindorf K, Friedenreich C, Linseisen J, Rohrmann S, Rundle A, Veglia F, Vineis P, Johnsen NF, Tjonneland A, Overvad K, Raaschou-Nielsen O, Clavel-Chapelon F, Boutron-Ruault MC, Schulz M, Boeing H, Trichopoulou A, Kalapothaki V, Koliva M, Krogh V, Palli D, Tumino R, Panico S, Monninkhof E, Peeters PH, Boshuizen HC, Bueno-de-Mesquita HB, Chirlaque MD, Agudo A, Larranaga N, Quiros JR, Martinez C, Barricarte A, Janzon L, Berglund G, Bingham S, Khaw KT, Key TJ, Norat T, Jenab M, Cust A, Riboli E (2006) Physical activity and lung cancer risk in the European Prospective Investigation into Cancer and Nutrition Cohort. Int J Cancer 119:2389–2397

    PubMed  CrossRef  CAS  Google Scholar 

  • Subramanian J, Govindan R (2007) Lung cancer in never smokers: a review. J Clin Oncol 25: 561–570

    PubMed  CrossRef  Google Scholar 

  • Tardon A, Lee WJ, Delgado-Rodriguez M, Dosemeci M, Albanes D, Hoover R, Blair A (2005) Leisure-time physical activity and lung cancer: a meta-analysis. Cancer Causes Control 16:389–397

    PubMed  CrossRef  Google Scholar 

  • Thun MJ, Henley SJ, Burns D, Jemal A, Shanks TG, Calle EE (2006) Lung cancer death rates in lifelong nonsmokers. J Natl Cancer Inst 98: 691–699

    PubMed  CrossRef  Google Scholar 

  • Thune I, Lund E (1997) The influence of physical activity on lung-cancer risk: a prospective study of 81, 516 men and women. Int J Cancer 70: 57–62

    PubMed  CrossRef  CAS  Google Scholar 

  • Tockman MS, Anthonisen NR, Wright EC, Donithan MG (1987) Airways obstruction and the risk for lung cancer. Ann Intern Med 106:512–518

    PubMed  CrossRef  CAS  Google Scholar 

  • Wakelee HA, Chang ET, Gomez SL, Keegan TH, Feskanich D, Clarke CA, Holmberg L, Yong LC, Kolonel LN, Gould MK, West DW (2007) Lung cancer incidence in never smokers. J Clin Oncol 25:472–478

    PubMed  CrossRef  Google Scholar 

  • Wannamethee SG, Shaper AG, Walker M (2001) Physical activity and risk of cancer in middle-aged men. Br J Cancer 85:1311–1316

    PubMed  CrossRef  CAS  Google Scholar 

  • Wasswa-Kintu S, Gan WQ, Man SF, Pare PD, Sin DD (2005) Relationship between reduced forced expiratory volume in one second and the risk of lung cancer: a systematic review and meta-analysis. Thorax 60:570–575

    PubMed  CrossRef  CAS  Google Scholar 

  • WCRF/AICR (2007) World Cancer Research Fund/American Institute for Cancer Research: food, nutrition, physical activity, and the prevention of cancer: a global perspective. AICR, Washington DC

    Google Scholar 

  • Wetmore C, Ulrich CM (2006) Mechanisms associating physical activity with cancer incidence: exercise and immune function. CRC Press, Taylor & Francis

    Google Scholar 

  • Yu H, Spitz MR, Mistry J, Gu J, Hong WK, Wu X (1999) Plasma levels of insulin-like growth factor-I and lung cancer risk: a case-control analysis. J Natl Cancer Inst 91:151–156

    PubMed  CrossRef  CAS  Google Scholar 

  • Yun YH, Lim MK, Won YJ, Park SM, Chang YJ, Oh SW, Shin SA (2008) Dietary preference, physical activity, and cancer risk in men: national health insurance corporation study. BMC Cancer 8:366

    PubMed  CrossRef  Google Scholar 

Download references

Acknowledgment

Aina Emaus was funded by the Norwegian Cancer Society (grant 05087) and Inger Thune was funded by The Research Council of Norway while working on this book chapter. The authors would like to express their appreciation for the helpful suggestions and discussions made by Jessica Clague and other colleagues at the Department of Etiology, City of Hope, CA, USA.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Aina Emaus .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and Permissions

Copyright information

© 2010 Springer Berlin Heidelberg

About this chapter

Cite this chapter

Emaus, A., Thune, I. (2010). Physical Activity and Lung Cancer Prevention. In: Courneya, K., Friedenreich, C. (eds) Physical Activity and Cancer. Recent Results in Cancer Research, vol 186. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-04231-7_5

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-04231-7_5

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-04230-0

  • Online ISBN: 978-3-642-04231-7

  • eBook Packages: MedicineMedicine (R0)