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Rare Tumors In Children and Adolescents pp 133–144Cite as

Thyroid Carcinomas

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Part of the book series: Pediatric Oncology ((PEDIATRICO))

Abstract

Thyroid cancers account for the most frequent tumors of endocrine glands in childhood and adolescence; however, these solid tumors are rare in this population. Currently, about 10% of all thyroid cancers occur in patients under 21 years of age (Buckwalter et al. 1981). The annual incidence as derived from the Surveillance, Epidemiology, and End Results (SEER) registry is 0.54 cases per 100,000 persons (Hogan et al. 2009).

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References

  • Aghini-Lombardi F, Antonangeli L, Martino E et al (1999) The spectrum of thyroid disorders in an iodine-deficient community: the Pescopagano survey. J Clin Endocrinol Metab 84(2):561–566

    Article  PubMed  CAS  Google Scholar 

  • Bargren AE, Meyer-Rochow GY, Delbridge LW, Sidhu SB, Chen H (2009) Outcomes of surgically managed pediatric thyroid cancer. J Surg Res 156(1):70–73

    Article  PubMed  Google Scholar 

  • Bell B, Mazzaferri EL (1993) Familial adenomatous polyposis (Gardner’s syndrome) and thyroid carcinoma. A case report and review of the literature. Dig Dis Sci 38(1):185–190

    Article  PubMed  CAS  Google Scholar 

  • Bergholm U, Bergstrom R, Ekbom A (1997) Long-term follow-up of patients with medullary carcinoma of the thyroid. Cancer 79(1):132–138

    Article  PubMed  CAS  Google Scholar 

  • Bhatia S, Yasui Y, Robison LL et al (2003) High risk of subsequent neoplasms continues with extended follow-up of childhood Hodgkin’s disease: report from the Late Effects Study Group. J Clin Oncol 21(23):4386–4394

    Article  PubMed  Google Scholar 

  • Brandi ML, Gagel RF, Angeli A et al (2001) Guidelines for diagnosis and therapy of MEN type 1 and type 2. J Clin Endocrinol Metab 86(12):5658–5671

    Article  PubMed  CAS  Google Scholar 

  • Brauckhoff M, Gimm O, Weiss CL et al (2004) Multiple endocrine neoplasia 2B syndrome due to codon 918 mutation: clinical manifestation and course in early and late onset disease. World J Surg 28(12):1305–1311

    Article  PubMed  Google Scholar 

  • Buckwalter JA, Gurll NJ, Thomas CG Jr (1981) Cancer of the thyroid in youth. World J Surg 5(1):15–25

    Article  PubMed  CAS  Google Scholar 

  • Chaukar DA, Rangarajan V, Nair N et al (2005) Pediatric thyroid cancer. J Surg Oncol 92(2):130–133

    Article  PubMed  Google Scholar 

  • Chen WK, Lee CH, Wang HC, Lui WY, Wei CF (1994) Thyroid cancer in children and adolescents. Zhonghua Yi Xue Za Zhi (Taipei) 54(6):400–406

    CAS  Google Scholar 

  • Chow SM, Law SC, Mendenhall WM et al (2004) Differentiated thyroid carcinoma in childhood and adolescence-clinical course and role of radioiodine. Pediatr Blood Cancer 42(2):176–183

    Article  PubMed  Google Scholar 

  • Cohen R, Campos JM, Salaun C et al (2000) Preoperative calcitonin levels are predictive of tumor size and postoperative calcitonin normalization in medullary thyroid carcinoma. Groupe d’Etudes des Tumeurs a Calcitonine (GETC). J Clin Endocrinol Metab 85(2):919–922

    Article  PubMed  CAS  Google Scholar 

  • Cohen MS, Phay JE, Albinson C et al (2002) Gastrointestinal manifestations of multiple endocrine neoplasia type 2. Ann Surg 235(5):648–654

    Article  PubMed  Google Scholar 

  • Collini P, Sampietro G, Pilotti S (2004) Extensive vascular invasion is a marker of risk of relapse in encapsulated non-Hurthle cell follicular carcinoma of the thyroid gland: a clinicopathological study of 18 consecutive cases from a single institution with a 11-year median follow-up. Histopathology 44(1):35–39

    Article  PubMed  CAS  Google Scholar 

  • Collini P, Massimino M, Leite SF et al (2006a) Papillary thyroid carcinoma of childhood and adolescence: a 30-year experience at the Istituto Nazionale Tumori in Milan. Pediatr Blood Cancer 46(3):300–306

    Article  PubMed  Google Scholar 

  • Collini P, Mattavelli F, Pellegrinelli A, Barisella M, Ferrari A, Massimino M (2006b) Papillary carcinoma of the thyroid gland of childhood and adolescence: morphologic subtypes, biologic behavior and prognosis: a clinicopathologic study of 42 sporadic cases treated at a single institution during a 30-year period. Am J Surg Pathol 30(11):1420–1426

    Article  PubMed  Google Scholar 

  • Collini P, Mattavelli F, Spinelli C, Massimino M (2007) Treatment of sporadic nonmedullary thyroid carcinomas in pediatric age. Expert Rev Anticancer Ther 7(1):23–30

    Article  PubMed  CAS  Google Scholar 

  • Crile G Jr (1966) Endocrine dependency of papillary carcinoma of the thyroid. JAMA 195(9):721–724

    Article  PubMed  Google Scholar 

  • Danese D, Gardini A, Farsetti A, Sciacchitano S, Andreoli M, Pontecorvi A (1997) Thyroid carcinoma in children and adolescents. Eur J Pediatr 156(3):190–194

    Article  PubMed  CAS  Google Scholar 

  • De Jong SA, Demeter JG, Lawrence AM, Paloyan E (1992) Necessity and safety of completion thyroidectomy for differentiated thyroid carcinoma. Surgery 112(4):734–737

    PubMed  Google Scholar 

  • De Keyser LF, Van Herle AJ (1985) Differentiated thyroid cancer in children. Head Neck Surg 8(2):100–114

    Article  PubMed  Google Scholar 

  • DeLellis RA, Lloyd RV, Heitz PU, Eng C (eds) (2004a) Pathology and genetics. Tumours of endocrine organs. In: World Health Organization Classification of Tumours. IARC, Lyon

    Google Scholar 

  • DeLellis RA, Lloyd RV, Heitz PU, Eng C (2004b) World Health Organization Classification of Tumours. Pathology and genetics of tumours of endocrine organs. IARC, Lyon

    Google Scholar 

  • Díaz-Soto G, Puig-Domingo M, Martínez-Pino I, Martínez de Osaba MJ, Mora M, Rivera-Fillat F, Halperin I (2011) Do thyroid cancer patients with basal undetectable Tg measured by current immunoassays require rhTSH testing? Exp Clin Endocrinol Diabetes 119:348–352.

    Article  PubMed  CAS  Google Scholar 

  • Dinauer CA, Breuer C, Rivkees SA (2008) Differentiated thyroid cancer in children: diagnosis and management. Curr Opin Oncol 20(1):59–65

    Article  PubMed  Google Scholar 

  • dos Santos Silva I, Swerdlow AJ (1993) Sex differences in the risks of hormone-dependent cancers. Am J Epidemiol 138(1):10–28

    PubMed  Google Scholar 

  • Farahati J, Bucsky P, Parlowsky T, Mader U, Reiners C (1997) Characteristics of differentiated thyroid carcinoma in children and adolescents with respect to age, gender, and histology. Cancer 80(11):2156–2162

    Article  PubMed  CAS  Google Scholar 

  • Farahati J, Parlowsky T, Mader U, Reiners C, Bucsky P (1998) Differentiated thyroid cancer in children and adolescents. Langenbecks Arch Surg 383(3–4):235–239

    Article  PubMed  CAS  Google Scholar 

  • Farahati J, Reiners C, Demidchik EP (1999) Is the UICC/AJCC classification of primary tumor in childhood thyroid carcinoma valid? J Nucl Med 40(12):2125

    PubMed  CAS  Google Scholar 

  • Frank-Raue K, Buhr H, Dralle H et al (2006) Long-term outcome in 46 gene carriers of hereditary medullary thyroid carcinoma after prophylactic thyroidectomy: impact of individual RET genotype. Eur J Endocrinol 155(2):229–236

    Article  PubMed  CAS  Google Scholar 

  • Franzius C, Dietlein M, Biermann M et al (2007) Procedure guideline for radioiodine therapy and 131iodine whole-body scintigraphy in paediatric patients with differentiated thyroid cancer. Nuklearmedizin 46(5):224–231

    PubMed  CAS  Google Scholar 

  • Gharib H, Goellner JR (1993) Fine-needle aspiration biopsy of the thyroid: an appraisal. Ann Intern Med 118(4):282–289

    PubMed  CAS  Google Scholar 

  • Gharib H, James EM, Charboneau JW, Naessens JM, Offord KP, Gorman CA (1987) Suppressive therapy with levothyroxine for solitary thyroid nodules. A double-blind controlled clinical study. N Engl J Med 317(2):70–75

    Article  PubMed  CAS  Google Scholar 

  • Hegedus L, Karstrup S (1998) Ultrasonography in the evaluation of cold thyroid nodules. Eur J Endocrinol 138(1):30–31

    Article  PubMed  CAS  Google Scholar 

  • Herle AJ, Uller RP (1975) Elevated serum thyroglobulin. A marker of metastases in differentiated thyroid carcinomas. J Clin Invest 56(2):272–277

    Article  PubMed  CAS  Google Scholar 

  • Hogan AR, Zhuge Y, Perez EA, Koniaris LG, Lew JI, Sola JE (2009) Pediatric thyroid carcinoma: incidence and outcomes in 1753 patients. J Surg Res 156(1):167–172

    Article  PubMed  Google Scholar 

  • Iihara M, Yamashita T, Okamoto T et al (1997) A nationwide clinical survey of patients with multiple endocrine neoplasia type 2 and familial medullary thyroid carcinoma in Japan. Jpn J Clin Oncol 27(3):128–134

    Article  PubMed  CAS  Google Scholar 

  • Jarzab B, Handkiewicz-Junak D (2007) Differentiated thyroid cancer in children and adults: same or distinct disease? Hormones (Athens) 6(3):200–209

    Google Scholar 

  • Jarzab B, Handkiewicz-Junak D, Wloch J (2005) Juvenile differentiated thyroid carcinoma and the role of radioiodine in its treatment: a qualitative review. Endocr Relat Cancer 12(4):773–803

    Article  PubMed  CAS  Google Scholar 

  • Kazakov VS, Demidchik EP, Astakhova LN (1992) Thyroid cancer after Chernobyl. Nature 359(6390):21

    Article  PubMed  CAS  Google Scholar 

  • Kloos RT, Eng C, Evans DB et al (2009) Medullary thyroid cancer: management guidelines of the American Thyroid Association. Thyroid 19(6):565–612

    Article  PubMed  Google Scholar 

  • Kuijt WJ, Huang SA (2005) Children with differentiated thyroid cancer achieve adequate hyperthyrotropinemia within 14 days of levothyroxine withdrawal. J Clin Endocrinol Metab 90(11):6123–6125

    Article  PubMed  CAS  Google Scholar 

  • La Quaglia MP, Corbally MT, Heller G, Exelby PR, Brennan MF (1988) Recurrence and morbidity in differentiated thyroid carcinoma in children. Surgery 104(6):1149–1156

    PubMed  Google Scholar 

  • Lanzi C, Cassinelli G, Nicolini V, Zunino F (2009) Targeting RET for thyroid cancer therapy. Biochem Pharmacol 77(3):297–309

    Article  PubMed  CAS  Google Scholar 

  • Lassaletta AL, Melchor Diaz MA, Gavilanes PJ, Martin HG, de Vergas GJ (1997) Thyroid nodules: factors suggestive of malignancy. Acta Otorrinolaringol Esp 48(3):220–224

    Google Scholar 

  • Levin KE, Clark AH, Duh QY, Demeure M, Siperstein AE, Clark OH (1992) Reoperative thyroid surgery. Surgery 111(6):604–609

    PubMed  CAS  Google Scholar 

  • Liesenkotter KP, Kiebler A, Stach B, Willgerodt H, Gruters A (1997) Small thyroid volumes and normal iodine excretion in Berlin schoolchildren indicate full normalization of iodine supply. Exp Clin Endocrinol Diabetes 105(Suppl 4):46–50

    Article  PubMed  Google Scholar 

  • Lugo-Vicente H, Ortiz VN (1998) Pediatric thyroid nodules: insights in management. Bol Asoc Med P R 90(4–6):74–78

    PubMed  CAS  Google Scholar 

  • Luster M, Handkiewicz-Junak D, Grossi A et al (2009) Recombinant thyrotropin use in children and adolescents with differentiated thyroid cancer: a multicenter retrospective study. J Clin Endocrinol Metab 94(10):3948–3953

    Article  PubMed  CAS  Google Scholar 

  • Machens A, Dralle H (2007) Genotype-phenotype based surgical concept of hereditary medullary thyroid carcinoma. World J Surg 31(5):957–968

    Article  PubMed  Google Scholar 

  • Machens A, Dralle H (2009) Age disparities in referrals to specialist surgical care for papillary thyroid cancer. Eur J Surg Oncol 35(12):1312–1317

    Article  PubMed  CAS  Google Scholar 

  • Massimino M, Collini P, Leite SF et al (2006) Conservative surgical approach for thyroid and lymph-node involvement in papillary thyroid carcinoma of childhood and adolescence. Pediatr Blood Cancer 46(3):307–313

    Article  PubMed  Google Scholar 

  • Melvin KE, Miller HH, Tashjian AH Jr (1971) Early diagnosis of medullary carcinoma of the thyroid gland by means of calcitonin assay. N Engl J Med 285(20):1115–1120

    Article  PubMed  CAS  Google Scholar 

  • Mettler FA Jr, Williamson MR, Royal HD et al (1992) Thyroid nodules in the population living around Chernobyl. JAMA 268(5):616–619

    Article  PubMed  Google Scholar 

  • Miccoli P, Antonelli A, Spinelli C, Ferdeghini M, Fallahi P, Baschieri L (1998) Completion total thyroidectomy in children with thyroid cancer secondary to the Chernobyl accident. Arch Surg 133(1):89–93

    Article  PubMed  CAS  Google Scholar 

  • Miccoli P, Minuto MN, Ugolini C et al (2008) Papillary thyroid cancer: pathological parameters as prognostic factors in different classes of age. Otolaryngol Head Neck Surg 138(2):200–203

    Article  PubMed  Google Scholar 

  • Milone F, Ramundo V, Chiofalo MG et al (2010) Predictive value of pentagastrin test for preoperative differential diagnosis between C-cell hyperplasia and medullary thyroid carcinoma in patients with moderately elevated basal calcitonin levels. Clin Endocrinol (Oxf) 73(1):85–88

    CAS  Google Scholar 

  • Modigliani E, Cohen R, Campos JM et al (1998) Prognostic factors for survival and for biochemical cure in medullary thyroid carcinoma: results in 899 patients. The GETC Study Group. Groupe d’etude des tumeurs a calcitonine. Clin Endocrinol (Oxf) 48(3):265–273

    Article  CAS  Google Scholar 

  • Newman KD, Black T, Heller G et al (1998) Differentiated thyroid cancer: determinants of disease progression in patients <21 years of age at diagnosis: a report from the Surgical Discipline Committee of the Children’s Cancer Group. Ann Surg 227(4):533–541

    Article  PubMed  CAS  Google Scholar 

  • Ng Tang Fui SC, Hoffenberg R, Maisey MN, Black EG (1979) Serum thyroglobulin concentrations and whole-body radioiodine scan in follow-up of differentiated thyroid cancer after thyroid ablation. Br Med J 2(6185):298–300

    Article  PubMed  CAS  Google Scholar 

  • Niedziela M (2006) Pathogenesis, diagnosis and management of thyroid nodules in children. Endocr Relat Cancer 13(2):427–453

    Article  PubMed  CAS  Google Scholar 

  • Ogilvie JB, Patel KN, Heller KS (2010) Impact of the 2009 American Thyroid Association guidelines on the choice of operation for well-differentiated thyroid microcarcinomas. Surgery 148(6):1222–1226

    Article  PubMed  Google Scholar 

  • Okayasu I, Fujiwara M, Hara Y, Tanaka Y, Rose NR (1995) Association of chronic lymphocytic thyroiditis and thyroid papillary carcinoma. A study of surgical cases among Japanese, and white and African Americans. Cancer 76(11):2312–2318

    Article  PubMed  CAS  Google Scholar 

  • Ott RA, Calandra DB, McCall A, Shah KH, Lawrence AM, Paloyan E (1985) The incidence of thyroid carcinoma in patients with Hashimoto’s thyroiditis and solitary cold nodules. Surgery 98(6):1202–1206

    PubMed  CAS  Google Scholar 

  • Parisi MT, Mankoff D (2007) Differentiated pediatric thyroid cancer: correlates with adult disease, controversies in treatment. Semin Nucl Med 37(5):340–356

    Article  PubMed  Google Scholar 

  • Pelttari H, Valimaki MJ, Loyttyniemi E, Schalin-Jantti C (2010) Post-ablative serum thyroglobulin is an independent predictor of recurrence in low-risk differentiated thyroid carcinoma: a 16-year follow-up study. Eur J Endocrinol 163(5):757–763

    Article  PubMed  CAS  Google Scholar 

  • Puxeddu E, Romagnoli S, Dottorini ME (2011) Targeted therapies for advanced thyroid cancer. Curr Opin Oncol 23:13–21.

    Article  PubMed  CAS  Google Scholar 

  • Ralli M, Cohan P, Lee K (2005) Successful use of recombinant human thyrotropin in the therapy of pediatric well-differentiated thyroid cancer. J Endocrinol Invest 28(3):270–273

    PubMed  CAS  Google Scholar 

  • Raue F, Frank-Raue K (2009) Genotype-phenotype relationship in multiple endocrine neoplasia type 2. Implications for clinical management. Hormones (Athens) 8(1):23–28

    Google Scholar 

  • Reeve T, Thompson NW (2000) Complications of thyroid surgery: how to avoid them, how to manage them, and observations on their possible effect on the whole patient. World J Surg 24(8):971–975

    Article  PubMed  CAS  Google Scholar 

  • Ron E, Modan B, Preston D, Alfandary E, Stovall M, Boice JD Jr (1989) Thyroid neoplasia following low-dose radiation in childhood. Radiat Res 120(3):516–531

    Article  PubMed  CAS  Google Scholar 

  • Rosai J, Carcangiu ML, DeLellis RA (2011) Tumors of the thyroid gland. In: Rosai J, Sobin H (eds) Atlas of tumor pathology. Armed Forces Institute of Pathology, Washington DC

    Google Scholar 

  • Ruegemer JJ, Hay ID, Bergstralh EJ, Ryan JJ, Offord KP, Gorman CA (1988) Distant metastases in differentiated thyroid carcinoma: a multivariate analysis of prognostic variables. J Clin Endocrinol Metab 67(3):501–508

    Article  PubMed  CAS  Google Scholar 

  • Schlumberger M, de Vathaire F, Travagli JP et al (1987) Differentiated thyroid carcinoma in childhood: long term follow-up of 72 patients. J Clin Endocrinol Metab 65(6):1088–1094

    Article  PubMed  CAS  Google Scholar 

  • Shaha AR (2008) Revision thyroid surgery - technical considerations. Otolaryngol Clin North Am 41(6):1169–1183, x

    Article  PubMed  Google Scholar 

  • Sherman SI (2010) Targeted therapy of thyroid cancer. Biochem Pharmacol 80(5):592–601

    Article  PubMed  CAS  Google Scholar 

  • Showalter TN, Siegel BA, Moley JF, Baranski TJ, Grigsby PW (2008) Prognostic factors in patients with well-differentiated thyroid cancer presenting with pulmonary metastasis. Cancer Biother Radiopharm 23(5):655–659

    Article  PubMed  Google Scholar 

  • Spinelli C, Bertocchini A, Antonelli A, Miccoli P (2004) Surgical therapy of the thyroid papillary carcinoma in children: experience with 56 patients  <  or =16 years old. J Pediatr Surg 39(10):1500–1505

    Article  PubMed  Google Scholar 

  • Stevens C, Lee JK, Sadatsafavi M, Blair GK (2009) Pediatric thyroid fine-needle aspiration cytology: a meta-analysis. J Pediatr Surg 44(11):2184–2191

    Article  PubMed  Google Scholar 

  • Szinnai G, Sarnacki S, Polak M (2007) Hereditary medullary thyroid carcinoma: how molecular genetics made multiple endocrine neoplasia type 2 a paediatric disease. Endocr Dev 10:173–187

    Article  PubMed  CAS  Google Scholar 

  • van Santen HM, Aronson DC, Vulsma T et al (2004) Frequent adverse events after treatment for childhood-onset differentiated thyroid carcinoma: a single institute experience. Eur J Cancer 40(11):1743–1751

    Article  PubMed  Google Scholar 

  • Verburg FA, Mäder U, Luster M, Reiners C (2009) Histology does not influence prognosis in differentiated thyroid carcinoma when accounting for age, tumour diameter, invasive growth and metastases. Eur J Endocrinol 160:619–624

    Article  PubMed  CAS  Google Scholar 

  • Verga U, Fugazzola L, Cambiaghi S et al (2003) Frequent association between MEN 2A and cutaneous lichen amyloidosis. Clin Endocrinol (Oxf) 59(2):156–161

    Article  CAS  Google Scholar 

  • Welch Dinauer CA, Tuttle RM, Robie DK et al (1998) Clinical features associated with metastasis and recurrence of differentiated thyroid cancer in children, adolescents and young adults. Clin Endocrinol (Oxf) 49(5):619–628

    Article  CAS  Google Scholar 

  • Wiersinga WM (2001) Thyroid cancer in children and adolescents–consequences in later life. J Pediatr Endocrinol Metab 14(Suppl 5):1289–1296

    PubMed  Google Scholar 

  • Yin M, King SK, Hutson JM, Chow CW (2006) Multiple endocrine neoplasia type 2B diagnosed on suction rectal biopsy in infancy: a report of 2 cases. Pediatr Dev Pathol 9(1):56–60

    Article  PubMed  Google Scholar 

  • Yip FW, Reeve TS, Poole AG, Delbridge L (1994) Thyroid nodules in childhood and adolescence. Aust N Z J Surg 64(10):676–678

    Article  PubMed  CAS  Google Scholar 

  • Zimmerman D, Hay ID, Gough IR et al (1988) Papillary thyroid carcinoma in children and adults: long-term follow-up of 1039 patients conservatively treated at one institution during three decades. Surgery 104(6):1157–1166

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Pediatric Unit, Fondazione IRCCS Istituto Nazionale Tumori, Via Venezian 1, 20133, Milano, Italy

    Maura Massimino

  2. Department of Pediatric Oncology, Otto-von-Guericke University Magdeburg, Leipziger Str. 44, 39120, Magdeburg, Germany

    Antje Redlich & Peter Vorwerk

  3. Pathology Department, Fondazione IRCCS Istituto Nazionale Tumori, Via Venezian 1, 20133, Milano, Italy

    Paola Collini

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  1. Maura Massimino
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  2. Antje Redlich
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  3. Paola Collini
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  4. Peter Vorwerk
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Correspondence to Maura Massimino .

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Editors and Affiliations

  1. Klinik für Kinder- und Jugendmedizin, Klinikum Dortmund gGmbH, Beurhausstr. 40, Dortmund, 44137, Germany

    Dominik T. Schneider

  2. Klinik für Kinder und Jugendliche, Universitätsklinikum Erlangen-Nürnberg, Loschgestr. 15, Erlangen, 91054, Germany

    Ines B. Brecht

  3. at Egleston, Dept. Pediatric Hematology/Oncology, Children's Healthcare of Atlanta, Uppergate Drive NE., 2015, Atlanta, 30322, Georgia, USA

    Thomas A. Olson

  4. Unità di Oncologia Pediatrica, Istituto Nazionale Tumori, Via G. Venezian 1, Milano, 20133, Italy

    Andrea Ferrari

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Massimino, M., Redlich, A., Collini, P., Vorwerk, P. (2012). Thyroid Carcinomas. In: Schneider, D., Brecht, I., Olson, T., Ferrari, A. (eds) Rare Tumors In Children and Adolescents. Pediatric Oncology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-04197-6_16

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