Diacylglycerol Kinase

  • Steven A. Arisz
  • Teun MunnikEmail author
Part of the Plant Cell Monographs book series (CELLMONO, volume 16)


Diacylglycerol kinase (DGK, EC is a lipid kinase that phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). DGK belongs to a well-conserved family of proteins found in diverse species, such as Saccharomyces cerevisiae, Drosophila melanogaster, Caenorhabditis elegans, mammals, plants, and bacteria (Merida et al. Biochem J 409:1–18, 2008). In eukaryotes, DGK can be activated in response to various stimuli, and its product PA is emerging as a novel lipid second messenger (Munnik, Trends Plant Sci 6:227–233, 2001; Testerink and Munnik, Trends Plant Sci 10:368–375, 2005). Despite similarities to the mammalian system, plant DGKs display several distinctive features.


Phosphatidic Acid Phosphatidic Acid Diacylglycerol Kinase Phosphatidic Acid Phosphatase Cold Shock Treatment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  1. 1.Section Plant Physiology, Swammerdam Institute for Life SciencesUniversity of AmsterdamAmsterdamThe Netherlands

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