Inositol Polyphosphates and Kinases
Since the turn of the century, an advent of discoveries has revealed novel functions of specific inositol phosphates in eukaryotic cells. Forward- and reverse-genetic approaches in plant systems have allowed for the identification of many of the genes involved in plant inositol phosphate metabolism. There appears to be a relatively small group of promiscuous kinases responsible for a plethora of reactions that potentially generate multiple and branched inositol phosphate pathways leading to phytate synthesis. This chapter describes the known plant inositol polyphosphate kinases, the inositol phosphates that are modified by them, and the possibility for emerging roles of these small molecules in plant biology.
KeywordsInositol Phosphate Inositol Polyphosphate COP9 Signalosome Inositol Ring Inositol Pyrophosphate
- Biswas S, Maity IB, Chakrabarti S, Biswas BB (1978) Purification and characterization of myo-inositol hexaphosphate-adenosine diphosphate phosphotransferase from Phaseolus aureus. Arch Biochem Biophys185:557–566Google Scholar
- Kim SI, Andaya CB, Goyal SS, Tai TH (2008) The rice OsLpa1 gene encodes a novel protein involved in phytic acid metabolism. Theor Appl Genet 117:769–779Google Scholar
- Yang X, Rudolf M, Carew MA, Yoshida M, Nerreter V, Riley AM, Chung SK, Bruzik KS, Potter BV, Schultz C, Shears SB (1999) Inositol 1,3,4-trisphosphate acts in vivo as a specific regulator of cellular signaling by inositol 3,4,5,6-tetrakisphosphate. J Biol Chem 274:18973–18980CrossRefPubMedGoogle Scholar