Liver cirrhosis is a term used to describe the histologi-cal development of regenerative hepatic nodules surrounded by fibrous bands in response to chronic liver injury.
Cirrhosis is an advanced, diffuse stage of liver injury, which is characterized by replacement of the normal liver parenchyma by collagenous scar (fibrosis). Cirrhosis is accompanied by diffuse distortion of the hepatic vasculature and architecture, resulting in vascular disturbance between the portal veins and the hepatic veins, plus porta hepatic fibrosis. The major cirrhosis consequences are hepatic function impairment, increased intrahepatic resistance (portal hypertension), and the development of hepatocellular carcinoma (HCC).
KeywordsPortal Hypertension Hepatic Encephalopathy Primary Biliary Cirrhosis Dysplastic Nodule Ligamentum Teres
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For Further Reading
Schuppan D et al Liver cirrhosis. Lancet. 2008;371:838–51PubMedCrossRefGoogle Scholar
Colli A et al Severe liver fibrosis or cirrhosis: accuracy of US for detection—analysis of 300 cases. Radiology. 2003; 227:89–94PubMedCrossRefGoogle Scholar
Ito K et al Imaging findings of unusual intra- and extrahe-patic portosystemic collaterals. Clin Radiol. 2009;64:200–07PubMedCrossRefGoogle Scholar
Meyer CA et al Diseases of the hepatopulmonary axis. RadioGraphics. 2000;20:687–98PubMedGoogle Scholar
Lim JH et al Regenerative nodules in liver cirrhosis: find- ings at CT during arterial portography and CT arteriogra-phy with histopathologic correlation. Radiology. 1999;210:451–58PubMedGoogle Scholar
Martinez-Noguera A et al Doppler in hepatic cirrhosis and chronic hepatitis. Semin Ultrasound CT MR. 2002;23:19–36PubMedCrossRefGoogle Scholar
Palazzi C et al Hepatitis C virus-related arthritis. Autoimmun Rev 2008;8:48–51PubMedCrossRefGoogle Scholar
Bonekamp S et al Can imaging modalities diagnose and stage hepatic fibrosis and cirrhosis accurately. J Hepatol. 2009;50:17–35Google Scholar
Chavhan GB et al Normal Doppler spectral-waves of major pediatric vessels: specific patterns. RadioGraphics 2008;28:691–706PubMedCrossRefGoogle Scholar
Ba-Ssalamah A et al Dedicated multi-detector CT of the esophagus: spectrum of diseases. Abdom Imaging. 2009;34:3–18PubMedCrossRefGoogle Scholar
Verma SK et al Dilated cisternae chyli: a sign of uncompen- sated cirrhosis at MR imaging. Abdom Imaging. 2009;34:211–16PubMedCrossRefGoogle Scholar
Sharma S et al MRI diagnosis of plantar fibromatosis—a rare anatomic location. The Foot. 2003;13:219–22CrossRefGoogle Scholar
Mauro MA et al Computed tomography of hepatic venous hypertension: the reticulated-mosaic pattern. Gastrointest Radiol. 1990;15:35–38PubMedCrossRefGoogle Scholar
Kobayashi S et al MRI findings of primary biliary cirrhosis: correlation with Scheuer histologic staging. Abdom Imaging. 2005;30:71–76PubMedCrossRefGoogle Scholar
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