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Investigation of Sleepiness Induced by Insomnia Medication Treatment and Sleep Deprivation

  • Ioanna Chouvarda
  • Emmanouil Michail
  • Athina Kokonozi
  • Luc Staner
  • Nathalie Domis
  • Nicos Maglaveras
Part of the Lecture Notes in Computer Science book series (LNCS, volume 5638)

Abstract

The main objective of this work is the study of EEG signals in order to investigate sleepiness induced from drug administration for insomnia and sleep deprivation. Data used in this work were obtained from real experiments in FORENAP, France and in CERTH, Thessaloniki, Greece. The features under consideration are Power Spectrum in certain frequency areas, alpha slow-wave index (ASI) and Fractal Dimension (FD) for placebo and verum subjects. Studying these features in the above groups, we found that sleepiness due to hypnotic medication and due to sleep deprivation can cause different behaviour in brain activity at certain locations. These EEG characteristics could be used for the classification of the medication intake (verum or placebo) and its effect.

Keywords

insomnia sleep deprivation EEG signals 

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References

  1. 1.
    De Gennaro, L., Ferrara, M., Curcio, G., Cristiani, R.: Antero-posterior EEG changes during the wakefulness-sleep transition. Clinical Neurophysiology 112, 1901–1911 (2001)CrossRefPubMedGoogle Scholar
  2. 2.
    Cajochen, C., Brunner, D.P., Kräuchi, K., Graw, P., Wirz-Jstice, A.: Power density in theta/alpha frequencies of the waking EEG progressively increases during sustained wakefulness. Sleep 18, 890–894 (1995)PubMedGoogle Scholar
  3. 3.
    Åkerstedt, T., Gillberg, M.: Subjective and objective sleepiness in the active individual. Int. J. Neurosci. 52, 29–37 (1990)CrossRefPubMedGoogle Scholar
  4. 4.
    Makeig, S., Jung, T.P.: Changes in alertness are a principal component of variance in the EEG spectrum. Neuroreport 7, 213–216 (1995)CrossRefPubMedGoogle Scholar
  5. 5.
    Portouli, E., Bekiaris, E., Papakostopoulos, V., Maglaveras, N.: On-road experiment for collecting driving behavioural data of sleepy drivers. Somnologie 11(4), 259–267 (2006)Google Scholar
  6. 6.
    Åkerstedt, T., Gillberg, M.: Subjective and objective sleepiness in the active individual. Int. J. Neurosci. 52, 29–37 (1990)CrossRefPubMedGoogle Scholar
  7. 7.
    Kaida, K., Takahashi, M., Åkerstedt, T., Nakata, A., Otsuka, Y., Haratani, T., Fukasawa, K.: Validation of the Karolinska sleepiness scale against performance and EEG variables. Clinical Neurophysiology 117, 1574–1581 (2006)CrossRefPubMedGoogle Scholar
  8. 8.
    Papadelis, C., Chen, Z., Kourtidou-Papadeli, C., Bamidis, P., Chouvarda, I., Bekiaris, E., Maglaveras, N.: Monitoring sleepiness with on-board electrophysiological recordings for preventing sleep-deprived traffic accident. Clinical Neurophysiology 118, 1906–1922Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2009

Authors and Affiliations

  • Ioanna Chouvarda
    • 1
  • Emmanouil Michail
    • 1
  • Athina Kokonozi
    • 1
  • Luc Staner
    • 2
  • Nathalie Domis
    • 2
  • Nicos Maglaveras
    • 1
  1. 1.Lab of Medical Informatics, the Medical SchoolAristotle University of ThessalonikiThessalonikiGreece
  2. 2.FORENAPRouffachFrance

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