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Barton–McCombie deoxygenation

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Deoxygenation of alcohols by means of radical scission of their corresponding thiocarbonyl derivatives.

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References

  1. Barton, D. H. R.; McCombie, S. W. J. Chem. Soc., Perkin Trans. 1 1975, 1574–1585. Stuart McCombie, a Barton student, now works at Schering–Plough.

    Google Scholar 

  2. Gimisis, T.; Ballestri, M.; Ferreri, C.; Chatgilialoglu, C.; Boukherroub, R.; Manuel, G. Tetrahedron Lett. 1995, 36, 3897–3900.

    Article  CAS  Google Scholar 

  3. Zard, S. Z. Angew. Chem., Int. Ed. 1997, 36, 673–685.

    CAS  Google Scholar 

  4. Lopez, R. M.; Hays, D. S.; Fu, G. C. J. Am. Chem. Soc. 1997, 119, 6949–6950.

    Article  CAS  Google Scholar 

  5. Hansen, H. I.; Kehler, J. Synthesis 1999, 1925–1930.

    Google Scholar 

  6. Boussaguet, P.; Delmond, B.; Dumartin, G.; Pereyre, M. Tetrahedron Lett. 2000, 41, 3377–3380.

    Article  CAS  Google Scholar 

  7. Cai, Y.; Roberts, B. P. Tetrahedron Lett. 2001, 42, 763–766.

    Article  CAS  Google Scholar 

  8. Clive, D. L. J.; Wang, J. J. Org. Chem. 2002, 67, 1192–1198.

    Article  CAS  Google Scholar 

  9. Rhee, J. U.; Bliss, B. I.; RajanBabu, T. V. J. Am. Chem. Soc. 2003, 125, 1492–1493.

    Article  CAS  Google Scholar 

  10. Gómez, A. M.; Moreno, E.; Valverde, S.; López, J. C. Eur. J. Org. Chem. 2004, 1830– 1840.

    Google Scholar 

  11. Deng, H.; Yang, X.; Tong, Z.; Li, Z.; Zhai, H. Org. Lett. 2008, 10, 1791–1793.

    Article  CAS  Google Scholar 

  12. Mancuso, J. Barton–McCombie deoxygenation. In Name Reactions for Homologations-Part I; Li, J. J., Corey, E. J., Eds.; Wiley & Sons: Hoboken, NJ, 2009, pp 614–632. (Review).

    Google Scholar 

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Correspondence to Jie Jack Li .

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© 2009 Springer-Verlag Berlin Heidelberg

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Li, J.J. (2009). Barton–McCombie deoxygenation. In: Name Reactions. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-01053-8_12

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