Keywords
- Liver Blood Flow
- Sinusoidal Endothelium
- Hepatic Drug Clearance
- Hepatic Sinusoidal Endothelium
- Injurious Insult
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Barber DJ, Fairhurst S, Horton AA (1983) Effect of old age on paracetamol induced lipid peroxidation in rat liver. Toxicol Lett 15: 283–7
Boyd WP (1933) Normal variability in weight of the adult human liver and spleen. Arch Pathol 16: 350–72
Cotran RS, Kumar V, Robbins SL (1999) Cellular aging. In: Robbins (ed), Pathologic basis of disease. 6th edn. WB Saunders, Philadelphia, PA, pp 45–8
David H, Peinke P (1988) Liver morphology with aging. In: Bianchi L (ed), Aging in liver and gastrointestinal tract. MTP, Lancester, pp 143–59
Fabbri AA, Marchesini A, Bianchi G, et al (1994) Hepatic nitrogen clearance in ageing man. Liver 14: 288–92
Hilmer SN, Coggger VC, Fraser R, et al. (2005) Age-related changes in the hepatic sinusoidal endothelium impede lipo-protein transfer in the rat. Hepatology 42: 1349–54
James OFW (1997) Parenchymal liver disease in the elderly. Gut 41: 430–2
Kitani K (1990) Aging and the liver. In: Popper H, Schaffner F (eds) Progress in liver disease, vol. 9, W.B. Saunders, Philadelphia, PA, pp 603–23
Le Couteur DG, Cogger VC, Markus AMA, et al (2001) Pseudocapillarization and associated energy limitation in the aged rat liver. Hepatology 33: 537–43
Le Couteur DG, Fraser R, Cogger VA, et al (2002) Hepatic pseudocapillarisation and atherosclerosis in ageing. Lancet 359: 1612–5
Liu Y, Guyton KZ, Gorospe M, et al (1996) Age-related decline in mitogen activated protein kinase activity in epidermal growth factor-stimulated rat hepatocytes. J Biochem 271: 3604–7
MacDonald RA (1971) “Lifespan” of liver cells. Arch Intern Med 107: 335–43
Sastre J, Pallardo FV, Pla R, et al (1996) Aging of the liver: age-associated mitochondrial damage in intact hepatocytes. Hepatology 24: 1199–205
Vestal RE (1989) Aging and determinants of hepatic drug clearance. Hepatology 9: 331–4
Weik C, Strohmeyer G (1999) Hepatobiliäre Erkrankungen im Alter. Dtsch med Wschr 124: 466–71
Wood AJJ, Vestal RE, Wilkinson GR, et al (1979) Effect of aging and cigarette smoking on antipyrine and indo-cyanine green elimination. Clin Pharmacol Ther 26: 16–20
Woodhouse KW, James OFW (1990) Hepatic drug metabolism and ageing. Br Med Bull 46: 22–35
Wynne HA, Cope LH, Mutch E, et al (1989) The effect of age upon liver volume and apparent liver blood flow in healthy man. Hepatology 9: 297–301
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2010 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Dancygier, H. (2010). Aging and the Liver. In: Clinical Hepatology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-93842-2_12
Download citation
DOI: https://doi.org/10.1007/978-3-540-93842-2_12
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-93841-5
Online ISBN: 978-3-540-93842-2
eBook Packages: MedicineMedicine (R0)