Abstract
The replacement of hip and knee joints has been a standard surgical procedure for decades. Around 1.3 million hip replacements and 1.0 million knee replacements are conducted annually worldwide, in Germany about 150,000 hip prostheses and around 100,000 knee prostheses are implanted (Bundesgeschäftsstelle Qualitätssicherung GGmbH 2006, Bundésgeschäftsstelle Qualitätssicherung GGmbH 2006; The Institute for Orthopaedics 2007). Up to a few years ago, the life of an endoprosthesis frequently exceeded the life expectancy of the patient. However, demographic trends along with increasing life expectancy mean that revision arthroplasty is becoming more importan (Sculco 1993). Thus in Sweden from 1995 to 2000 already around 8% of the hip total prostheses were revised and from 1995 to 2004 around 6% of the knee total prostheses (Kärrholm et al. 2007; Lidgren and Robertsson 2006).
Participating physicians: Constantin Baumgarte, Kiel, Germany, Basilio José de la Torre, Guadalajara, Spain, Jürgen Esper, Nuremberg, Germany, Philipp Funovics, Vienna, Austria, Hrubina Maroš, Pelhřimov, Czech Republic, Matthias Kemmerer, Frankfurt/Main, Germany, Kozák Martin, Karviná-Ráj, Czech Republic, Andreas Kostka, Berlin, Germany, Wilfried Materna, Graz, Austria, Christian Melzer, Bad Düben, Germany, Molano Muñoz, Vitoria, Spain, Andreas Peters, Frankfurt/Main, Germany, Martin Rieger, Bremen, Germany, Martin Stuhlinger, Reutlingen, Germany, Fernando Trell, Valdemoro, Spain
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Literature
Bauer TW, Parvizi J, Kobayashi N, Krebs V (2006) Diagnosis of periprosthetic infection. J Bone Joint Surg Am 88: 869–882
Blom AW, Taylor AH, Pattison G, Whitehouse S, Bannister GC (2003) Infection after total hip arthroplasty. The Avon experience. J Bone Joint Surg Br 85: 956–959
Buchholz H, Engelbrecht H (1970) Über die Depotwirkung einiger Antibiotika bei Vermischung mit dem Kunstharz Palacos. Chirurg 41: 511–515
Bundesgeschäftsstelle Qualitätssicherung GGmbH (2006) Hüft-Endoprothesen-Erstimplantation. http://www.bqsoutcome.de/2006/ergebnisse/leistungsbereiche/hueft_endo_erst/download
Bundesgeschäftsstelle Qualitätssicherung GGMBH (2007) Knie-Totalendoprothesen-Erstimplantation. http://www.bqs-outcome.de/2007/ergebnisse/leistungsbereiche/knie_tep_erst/index_html
Darouiche RO (2004) Treatment of infections associated with surgical implants. N Engl J Med 350:1422–1429
Elson RA (1993) Exchange arthroplasty for infection. Perspectives from the United Kingdom. Orthop Clin North Am 24: 761–767
Engesaeter LB, Lie SA, Espehaug B, Furnes O, Vollset SE, Havelin LI (2003) Antibiotic prophylaxis in total hip arthroplasty: effects of antibiotic prophylaxis systemically and in bone cement on the revision rate of 22,170 primary hip replacements followed 0–14 years in the Norwegian Arthroplasty Register. Acta Orthop Scand 74: 644–651
Espehaug B, Engesaeter LB, Vollset SE, Havelin LI, Langeland N (2007) Antibiotic prophylaxis in total hip arthroplasty. Review of 10,905 primary cemented total hip replacements reported to the Norwegian arthroplasty register, 1987 to 1995. J Bone Joint Surg Br 79: 590–595
Fitzgerald BH Jr (1992) Total hip arthroplasty sepsis. Prevention and diagnosis. Orthop Clin North Am 23: 259–264
Frommelt L (2004) Lokale Antibiotikatherapie. In: Schnettler S (Hrsg) Septische Knochenchirurgie. Thieme, Stuttgart, New York,S 82–90
Frommelt L (2007) Antibiotic choices in bone surgery — local therapy using antibiotic-loaded bone cement. In: Walenkamp GHIM (ed) Local antibiotics in arthroplasty. State of the art from an interdisciplinary view. Thieme, Stuttgart New York, pp 59–64
Frommelt L, Kühn KD (2005) Antibiotic-loaded cement. In: Breusch SJ, Malchau M (eds) The well-cemented total hip arthroplasty. Springer, Berlin Heidelberg New York Tokyo, pp 86–92
Garvin KL, Hanssen AD (1995) Infection after total hip arthroplasty Past, present, and future. J Bone Joint Surg Am 77: 1576–1588
Gehrke T (1998) Neuer antibiotikahaltiger Knochenzement. Medizin Forum aktuell 64
Gehrke T, v. Foerster G, Frommelt L, Marx A (2001) Pharmacokinetic study of a gentamicin/clindamycin bone cement used in one-stage revision arthroplasty. In: Walenkamp GHIM, Murray DW (eds) Bone cements and cementing technique. Springer, Berlin Heidelberg New York Tokyo, pp 127–134
Gristina AG, Naylor PT, Myrvik QN (1991) Mechanisms of musculoskeletal sepsis. Orthop Clin North Am 22: 363–371
Jamsen E, Huhtala H, Puolakka T, Moilanen T (2009) Risk factors for infection after knee arthroplasty. A register-based analysis of 43,149 cases. J Bone Joint Surg Am 91: 38–47
Josefsson G, Kolmert L (1993) Prophylaxis with systematic antibiotics versus gentamicin bone ement in total hip arthroplasty. A ten-year survey of 1,688 hips. Clin Orthop Relat Res 210–214
Kärrholm J, Garellick G, Rogmark C, Herberts P (2007) The Swedish hip arthroplasty register. Annual Report 2006. [Internet] http://www.jru.orthop.gu.se/2007
Kühn KD (2000) Bone cements. Up-to-date comparison of physical and chemical properties of commercial materials. Springer, Berlin, Heidelberg New York Tokyo
Kühn KD (2007) Antibiotic-loaded bone cements — antibiotic release and influence on mechanical properties. In: Walenkamp GHIM, ed. Local antibiotics in arthroplasty. State of the art from an interdisciplinary view. Thieme, Stuttgart, New York, pp 47–58
Kühn KD, Ege W, Gopp U (2005) Acrylic bone cements: composition and properties. Orthop Clin North Am 36: 17–28.
Kurtz S, Lau E, Zhao K, Mowat F, Ong K, Halpern M (2006) The future burden of hip and knee revisions. US projections from 2005 to 2030. 73rd Meeting of the American Academy of Orthopaedic Surgeons. Chicago, USA
Lidgren L, Robertsson O (2006) The Swedish Knee Arthroplasty Register 2005. Department of Orthopedics, Lund University Hospital
Musso AD, Mohanty K, Spencer-Jones R (2003) Role of frozen section histology in diagnosis of infection during revision arthroplasty. Postgrad Med J 79: 590–593
Neut D, van Horn JR, van Kooten TG, van der Mei HC, Busscher HJ (2003) Detection of biomaterial-associated infections in orthopaedic joint implants. Clin Orthop Relat Res 261–268
Parvizi J, Saleh KJ, Ragland PS, Pour AE, Mont MA (2008) Efficacy of antibiotic-impregnated cement in total hip replacement. Acta Orthop 79: 335–341
Peersman G, Laskin R, Davis J, Peterson M (2001) Infection in total knee replacements: Clin Orthop Relat Res 15–23
Sanzen L, Carlsson AS (1989) The diagnostic value of C-reactive protein in infected total hip arthroplasties. J Bone Joint Surg Br 71: 638–641
Sculco TP (1993) The economic impact of infected total joint arthroplasty. Instr Course Lect 42: 349–351
Sheng PY, Konttinen L, Lehto M et al. (2006) Revision total knee arthroplasty: 1990 through 2002. A review of the Finnish arthroplasty registry. J Bone Joint Surg Am 88: 1425–1430
Soderman P, Malchau H, Herberts P (2000) Outcome after total hip arthroplasty: Part I. General health evaluation in relation to definition of failure in the Swedish National Total Hip Arthoplasty register. Acta Orthop Scand 71: 354–359
Spangehl MJ, Masri BA, O’Connell JX, Duncan CP (1999) Prospective analysis of preoperative and intraoperative investigations for the diagnosis of infection at the sites of two hundred and two revision total hip arthroplasties. J Bone Joint Surg Am 81: 672–683
The Institute for Orthopaedics (2008) The 2007–2008 orthopaedics industry annual report. Chagrin Falls, Ohio, USA
Trampuz A, Zimmerli W (2005) Prosthetic joint infections: update in diagnosis and treatment. Swiss Med Wkly 135: 243–251
Tunney MM, Patrick S, Curran MD, et al. (1999) Detection of prosthetic hip infection at revision arthroplasty by immunofluorescence microscopy and PCR amplification of the bacterial 16S rRNA gene. J Clin Microbiol 37: 3281–3290
van de Belt H, Neut D, Schenk W, van Horn JR, van der Mei HC, Busscher HJ (2001) Infection of orthopedic implants and the use of antibiotic-loaded bone cements. A review. Acta Orthop Scand 72: 557–571
White J, Kelly M, Dunsmuir R (1998) C-reactive protein level after total hip and total knee replacement. J Bone Joint Surg Br 80: 909–911
Zimmerli W, Trampuz A, Ochsner PE (2004) Prosthetic-joint infections. N Engl J Med 351: 1645–1654
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2009 Springer Medizin Verlag Heidelberg
About this chapter
Cite this chapter
Sauer, J. (2009). Observational Study of Bone Cement with Two Antibiotics in Revision Arthroplasty of Knee and Hip. In: Kienapfel, H., Kühn, KD. (eds) The Infected Implant. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-92836-2_10
Download citation
DOI: https://doi.org/10.1007/978-3-540-92836-2_10
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-92835-5
Online ISBN: 978-3-540-92836-2
eBook Packages: MedicineMedicine (R0)