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Integration of microneedle-arrays and micro pumps in disposable and cheap drug delivery devices

  • Conference paper
4th European Conference of the International Federation for Medical and Biological Engineering

Part of the book series: IFMBE Proceedings ((IFMBE,volume 22))

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Abstract

Microneedle-arrays offer the chance to establish a fluidic interface between a drug delivery device and the human body. By bypassing the rate limiting diffusion barrier (skin) one is able to deliver a wide range of molecules. Novel physicochemical pumping concepts offer the possibility of controlling the time of delivery without any electronic control and thus enable the realization of cheap and disposable night time dosing devices.

Infusion studies and experimental data of drug delivery components presented in this paper demonstrate the feasibility of delivering a drug to the patient hours after starting the drug delivery device.

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References

  1. Ionsys by Ortho-McNeil-Janssen Pharmaceuticals at http://www.ortho-mcneil.com

    Google Scholar 

  2. PassPort Patch by Altea Therapeutics Corporation http://www.alteatherapeutics.com

    Google Scholar 

  3. ViaDerm System by TransPharma Medical Ltd. http://www.transpharma-medical.com

    Google Scholar 

  4. Vosseler M, Hradetzky D, Zengerle R (2007) Transdermale Medikamentendosiersysteme — Eine Option für die Chronopharmakologie?, 41. Jahrestagung der DGBMT, Aachen, Germany, 2007

    Google Scholar 

  5. Gardeniers H J G E, Luttge R, Berenschot E J W et al. (2003) Silicon Micromachined Hollow Microneedles for Transdermal Liquid Transport. JMEMS 12:855–862

    Google Scholar 

  6. Griss P, Stemme G (2003) Side-Opened Out-of-Plane Microneedles for Microfluidic Transdermal Liquid Transfer. JMEMS 12:296–301

    Google Scholar 

  7. Vosseler M, Kain A, Hradetzky D et al. (2008) Medical Grade Plastic Microneedles and an Evaluation-Kit for the Characterisation of Intradermal Microinfusions, PPP Conference, Vol. 11, La Grande Motte, France, 2008, pp 39

    Google Scholar 

  8. Martanto W, Moore J S, Kashlan O et al. (2006) Microinfusion Using Hollow Microneedles Pharm Res 23:104–113

    Google Scholar 

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Author information

Authors and Affiliations

  1. Institute of Micromachining and Information Technology (HSG-IMIT), Hahn-Schickard-Gesselschaft, Villingen-Schwenningen, Germany

    Michael Vosseler, M. Jugl, M. Blaesing, D. Hradetzky, S. Messner & R. Zengerle

  2. Department of Microsystems Engineering (IMTEK), Laboratory for MEMS Applications, Freiburg, Germany

    R. Zengerle

Authors
  1. Michael Vosseler
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  2. M. Jugl
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  3. M. Blaesing
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  4. D. Hradetzky
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  5. S. Messner
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  6. R. Zengerle
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Corresponding author

Correspondence to Michael Vosseler .

Editor information

Editors and Affiliations

  1. Biomechanics and Engineering Design Section, KULeuven, Celestijnenlaan 300c - bus 2419, 3001, Heverlee, Belgium

    Jos Vander Sloten

  2. Cardiovascular Mechanics and Biofluid Dynamics Research Unit, Ghent University, De Pintelaan 185, 9000, Gent, Belgium

    Pascal Verdonck

  3. Medical Informatics Department, Free University Brussels, Laarbeeklaan 103, 1090, Brussels, Belgium

    Marc Nyssen

  4. Institute for Biomedical Engineering and Informatics, Technical University of Ilmenau, P.O. Box 100565, 98639, Ilmenau, Germany

    Jens Haueisen

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© 2009 Springer-Verlag Berlin Heidelberg

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Cite this paper

Vosseler, M., Jugl, M., Blaesing, M., Hradetzky, D., Messner, S., Zengerle, R. (2009). Integration of microneedle-arrays and micro pumps in disposable and cheap drug delivery devices. In: Vander Sloten, J., Verdonck, P., Nyssen, M., Haueisen, J. (eds) 4th European Conference of the International Federation for Medical and Biological Engineering. IFMBE Proceedings, vol 22. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-89208-3_567

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  • DOI: https://doi.org/10.1007/978-3-540-89208-3_567

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-89207-6

  • Online ISBN: 978-3-540-89208-3

  • eBook Packages: EngineeringEngineering (R0)

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