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Weibliches Becken

  • J. Bahnsen
  • G. Hänsgen
  • W. Harms
Chapter

Zusammenfassung

Tab. 29.1 zeigt, dass Tumoren der Organe des weiblichen Beckens 11,5 % aller Tumoren der Frau ausmachen.

Literatur

  1. Albano, M, Dumas, Dumas I, Haie-Meder M (2008) [Brachytherapy at the Institut-Gustave-Roussy: personalized vaginal mould applicator: technical modification and improvement] [Article in French] Cancer Radiother 12:822–6PubMedGoogle Scholar
  2. Alvarez RD, Soong SJ, Kinney WK et al. (1989) Identification of prognostic factors and risk groups in patients found to have nodal metastasis at the time of radical hysterectomy for early stage squamous carcinoma of the cervix. Gynecol Oncol 35:130–135PubMedGoogle Scholar
  3. Annweiler H, Sack H (1996) Cervix uteri. In: Scherer E, Sack H (Hrsg) Strahlentherapie. Radiologische Onkologie. Springer, Berlin Heidelberg New York Tokio, S 589–628Google Scholar
  4. ARO (Arbeitsgemeinschaft Radioonkologie der DKG) (2010) http://www.aro-dkg.de/studien.htm. Zugegriffen: 30. April 2013
  5. Ball HG, Blessing JA, Lentz SS et al. (1996) A phase II trial of paclitaxel in patients with advanced or recurrent adenocarcinoma of the endometrium: a Gyecologic Oncology Group study. Gynecol Oncol 62:278–281PubMedGoogle Scholar
  6. Beadle BM, Jhingran A, Yom BM et al. (2010) Patterns of regional recurrence after definitive radiotherapy for cervical cancer. Int J Radiat Oncol Biol Phys 76:1396–403PubMedGoogle Scholar
  7. Boronow RC (1991) Combined radiation and surgery for locally advanced cancer of the vulva. In: Knappstein PG, di Re F, DiSaia P, Haller U Sevin B-U (eds) Malignancies of the vulva. Thieme, Stuttgart New York, S 133–142Google Scholar
  8. Burr RC, Robertson EM (1968) Value of radiation therapy in the treatment of cancer of the endometrium. Canad Med Assoc J 99:206–211PubMedGoogle Scholar
  9. Cardenas J, Ol guin A, Figueroa F et al. (1991) Randomized neoadjuvant chemotherapy in cervical carcinoma stage IIB: PEC + RT versus RT. Proc Am Soc Oncol 10 (Abstract)Google Scholar
  10. Chatani M, Nose T, Masaki N, Inoue T (1998) Adjuvant radiotherapy after radical hysterectomy of the cervical cancer. Prognostic factors and complications. Strahlenther Onkol 174:504–509PubMedGoogle Scholar
  11. Carmichael JA, Bean HA (1967) Carcinoma of the endometrium in Saskatchewan. A review of 603 cases with a suggested scheme of management for patients with stage I disease and regarded as good surgical risk. Amer J Obstet Gynecol 97:294–307Google Scholar
  12. Chauvergne J, Rohart J, Heron JF et al. (1990) Essai randomise de chimiotherapie initiale dans 151 carcinomes du col uterin localement etendus (T2b-N1, T3b, Mo). Bull Cancer 77:1007–1024PubMedGoogle Scholar
  13. Cohen JG, Kapp DS, Shin JG et al. (2010) Small cell carcinoma of the cervix: treatment and survival outcomes of 188 patients. Am J Obstet Gynecol:e1–e6Google Scholar
  14. Creutzberg CL, van Putten WL, Koper PC et al. (2001) The morbidity of treatment for patients with Stage I endometrial cancer: results from a randomized trial. Int J Radiat Oncol Biol Phys 51:1246–1255PubMedGoogle Scholar
  15. Dembo AJ, Bush RS, Beale FA et al. (1979) Ovarian carcinoma: Improved survival following abdominopelvic irradiation in patients with a complete pelvic operation. Amer J Obstet Gynecol 134:793–800Google Scholar
  16. DiSilvestro PA, et al. (2012) A Gynecologic Oncology Group phase III randomized trial of weekly cisplatin and radiation versus cisplatin and tirapazamine and radiation in stage IB2, IIA, IIIB and IVA cervical carcinoma limited to the pelvisGoogle Scholar
  17. Gynecol Oncol 125(s1): 3–4 (Abstrac)Google Scholar
  18. Dixit S, Singhal S, Baboo HA (1993) Squamous cell carcinoma of the vagina: a rewiew of 70 cases. Gynecol Oncol 48:80–87PubMedGoogle Scholar
  19. EBM (2003) Evidence Based Medicine Level. Antes G, Bassler D, Forster J: Evidenzbasierte Medizin. Thieme, Stuttgart New YorkGoogle Scholar
  20. Eifel PJ, Levenback C, Wharton JT et al. (1995) Time course and incidence of late complications in patients treated with radiation therapy for FIGO stage IB carcinoma of the uterine cervix. Int J Radiat Oncol Biol Phys 32:1289–1300PubMedGoogle Scholar
  21. Einhorn N, Trope C, Ridderheim M, Boman K, Sorbe B, Cavallin-Stahl E (2003) A systematic overview of radiation therapy effects in cervical cancer (cervix uteri). Acta Oncol 42:546–556PubMedGoogle Scholar
  22. Eitan R, Levavi H, Peled Y et al. (2010) Should simple hysterectomy be added after chemo-radiation for stage IB2 and bulky IIA cervical carcinoma? Aust N Z J Obstet Gynecol 50: 289–293Google Scholar
  23. Emons G, Kimmig R, Bechmann W (2009) Interdisziplinäre Leitlinie der deutschen Krebsgesellschaft e.V. (DKG) und der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe (DKG). AWMF-Leilinienregister Nr. 032/034Google Scholar
  24. EORTC (2010) http://www.eortc.org/clinical-trials. Zugegriffen: 20. Juni 2013
  25. Fanning J (2001) Long-term survival of intermediate risk endometrial cancer (stage IG3, IC, II) treated with full lymphadenectomy and brachytherapy without teletherapy. Gynecol Oncol 82:371–374PubMedGoogle Scholar
  26. Fletcher GH (1980) Textbook of radiotherapy. Lea & Febiger, Philadelphia, BaltimoreGoogle Scholar
  27. Frischbier H-J (1986) Die Strahlentherapie des Vulvakarzinoms (Hamburger Methode). In: Zander J, Baltzer J (Hrsg) Erkrankungen der Vulva. Urban & Schwarzenberg, München Wien, S 161–167Google Scholar
  28. Gaffney DK, Winter K, Dicker AP et al. (2007) Efficacy and pattern of failure for locally advanced cancer of the cervix treated with celebrex (celecoxib) and chemoradiotherapy in RTOG 0128. IJROBP 69:111–117Google Scholar
  29. Gerszten, K, Selvaraj, Selvaraj RN, Kelley K et al. (2005) Preoperative chemoradiation for locally advanced carcinoma of the vulva. Gynecol Oncol 3: 640–644Google Scholar
  30. Glaser FH (1988) Comparison of HDR afterloading with 192-Ir versus conventional radium therapy in cervix cancer: 5-year results and complications. In: Vahrson H, Rauthe G (eds) High dose rate afterloading in the treatment of cancer of the uterus, breast, and rectum. Urban & Schwarzenberg, München Wien, pp 106–113Google Scholar
  31. Gonzalez D, Ketting BW, van Bunningen B et al. (1989) Carcinoma of the uterine cervix stage IB and IIA: Results of postoperative irradiation in patients with microscopic infiltration in the parametrium and/or lymph node metastasis. Int J Radiat Oncol Biol Phys 16:389–395Google Scholar
  32. Gunthert AR, Achermann S, Beckmann MW et al.: Phase II study of weekly doxetaxel in patients with recurrent or metastatic endometrial cancer: AGO Uterus-4. Gynecol Oncol 104 (2007): 86–90PubMedGoogle Scholar
  33. Gusberg SB, Yannopoulos D (1964) Therapeutic decision in corpus cancer. Amer J Obstet Gynecol 88:157Google Scholar
  34. Haensgen G, Nagel M, Dunst J et al. (1999) Die postoperative Strahlentherapie beim Endometriumkarzinom. Eine retrospektive Analyse von 541 Patienten. Strahlenth Onc 175:548–553Google Scholar
  35. Haie C, Pejovic H, Gerbaulet A et al. (1988) Is prophylactic para-aortic irradiation worthwile in the treatment of advanced cervical carcinoma? Results of a controlled clinical trial of the EORTC radiotherapy group. Radiother Oncol 11:102–112Google Scholar
  36. Hamburgisches Krebsregister (2010) Hamburger Krebsdokumentation. Behörde für Arbeit, Gesundheit und Soziales, HamburgGoogle Scholar
  37. Hamilton, CA, Cheung, Cheung MK, Osann CA et al. (2006) The effect of adjuvant chemotherapy versus whole abdominopelvic radiation on the survival of patients with advanced stage uterine papillary serous carcinoma. Gynecol Oncol. 103:679–683.PubMedGoogle Scholar
  38. Hammer J, Zoidl JP, Altendorfer C et al. (1993) Combined external and high-dose rate intracavitary radiotherapy in the primary treatment of cancer of the uterine cervix. Radiother Oncol 27:66–68PubMedGoogle Scholar
  39. Herbolsheimer M, Rotte K (1997) Cancer of the endometrium. In: Vahrson HW (ed) Radiation oncology of gynecologic cancers. Springer, Berlin Heidelberg New York Tokio, pp 242–296Google Scholar
  40. Höckel M, Knapstein PG, Hohenfellner R et al. (1993) Die kombinierte operative und radiotherapeutische Behandlung (CORT) von Beckenwandrezidiven: Erfahrungsbericht nach 3 Jahren. Geb Fra 53:169–176Google Scholar
  41. Höckel M, Schlenger K, Höckel S, Vaupel P (1999) Association between tumor hypoxia and malignant progression: The clinical evidence in cancer of the uterine cervix. In: Vaupel P, Kelleher DK (eds) Tumor hypoxia. Wissenschaftliche Verlagsgesellschaft, Stuttgart, pp 65–74Google Scholar
  42. Höckel M, Vaupel P (2001) Biological consequences of tumor hypoxia. Semin Oncol 28, 2 (Suppl 8):36–41Google Scholar
  43. Höller U, Hoecht S, Wudel E, Hinkelbein W (2001) Osteoradionekrose nach Strahlentherapie gynäkologischer Tumoren. Strahlenther Onkol 177:291–295PubMedGoogle Scholar
  44. Homesley HD, Bundy BN, Sedlis A et al. (1993) Prognostic factors for groin node metastasis in squamous cell carcinoma of the vulva (a Gynecologic Oncologic Group study). Gynecol Oncol 49:279–283PubMedGoogle Scholar
  45. Homesley HD, Bundy BN, Sedlis A et al. (1991) Assessment of current International Federation of Gynecology and Obstetrics staging of vulvar carcinoma relative to prognostic factors for survival (a Gynecologic Oncology Group study). Amer J Obstet Gynecol 164:997–1004Google Scholar
  46. Horiot JC, Pigneux J, Pourquir H et al. (1988) Radiotherapy alone in carcinoma of the intact cervix according to GH Fletcher guidelines: a French cooperative study of 1383 cases. Int J Radiat Oncol Biol Phys 14:605–611PubMedGoogle Scholar
  47. Humber C, Tierney J, Symonds P et al. (2007) Chemotherapy for advanced, recurrent or metastatic endometrial cancer: a systematic review of Cochrane collaboration. Ann Oncol 18:409–420PubMedGoogle Scholar
  48. Inoue T, Morita K (1995) Long-term observation of patients treated by postoperative extended-field irradiation for nodal metastases from cervical carcinoma stages IB, IIA, and IIB. Gynecol Oncol 58:4–10PubMedGoogle Scholar
  49. Jacobs H (1997) Use of interstitial brachytherapy in the management of progression and recurrences. In: Vahrson HW (ed) Radiation oncology of gynecologic cancers. Springer, Berlin Heidelberg New York Tokio, pp 89–94Google Scholar
  50. Kaneyasu et al. (2012) Treatment Outcome of Medium-Dose-Rate Intracavitary Brachytherapy for Carcinoma of the Uterine Cervix: Comparison With Low-Dose_Rate Intracavitary Brachytherapy. Int J Radiation Oncol Biol Phys. 84:137–145Google Scholar
  51. Keys HM, Bundy BN, Stehman FB et al. (1999) Cisplatin, radiation, and adjuvant hysterectomy compared with radiation and adjuvant hysterectomy for bulky stage IB cervical carcinoma. N Engl J Med 340:1154–1161PubMedGoogle Scholar
  52. Kim JH, KIM HJ, Hong S, Wu HG, Ha SW (2005) Post-hysterectomy radiotherapy in FIGO stage IB – IIB uterine cervical carcinoma. Gynecol Oncol 96:407–414PubMedGoogle Scholar
  53. Klötzer KH, Günther R, Wendt T (1997) Die Vaginalstumpf-Rezidivrate beim Endometriumkarzinom in Abhängigkeit des Zielvolumens der postoperativen HDR-Afterloading-Brachytherapie. Strahlenther Onkol 173:13–17Google Scholar
  54. Knapstein PG, di Re F, DiSaia P et al. (1991) Malignancies of the vulva. Thieme, Stuttgart New YorkGoogle Scholar
  55. Krebs in Deutschland 2007/2008. Eine gemeinsame Veröffentlichung des Robert Koch-Instituts und der Gesellschaft der epidemiologischen Krebsregister in Deutschland e. V 8. Ausgabe, 2012Google Scholar
  56. Kucera H (1988) Experiences with HDR afterloading in endometrium cancer and results. Sonderb Strahlenth Onkol 82:228–236Google Scholar
  57. Kucera H (1990) Die Bedeutung der postoperativen Strahlentherapie beim Zervix- und Korpuskarzinom (The significance of postoperative radiotherapy in cervix and uterine cancer). Wien Med Wochenschr 140:502–506PubMedGoogle Scholar
  58. Kucera H (1992) Ergebnisse und Nebenwirkungen der postoperativen Strahlentherapie beim Korpuskarzinom. In: Ladner H-A, Pfleiderer A, Profous CZ (Hrsg) Gynäkologische Radiologie. Springer, Berlin Heidelberg New York Tokio, S 26–34Google Scholar
  59. Kucera H (1990) Therapieformen und -techniken bei der Bestrahlung des Korpuskarzinoms. In: Baier K, Herbolsheimer M, Sauer O (Hrsg) Interdisziplinäre Behandlungsformen beim Mammakarzinom und bei gynäkologischen Malignomen. DE Wachholz, Nürnberg, S 125–129Google Scholar
  60. Kucera H, Mock U, Knocke TH et al. (2001) Radiotherapy alone for invasive vaginal cancer: outcome with intracavitary high dose rate brachytherapy versus conventional low dose rate brachytherapy. Acta obstet gynecol scand 80:355–360PubMedGoogle Scholar
  61. Kucera K (1997) Electroresection, coagulation, and groin radiotherapy (Viennese methode). In: Vahrson HW (ed) Radiation oncology of gynecologic cancers. Springer, Berlin Heidelberg New York Tokio, S 80–82Google Scholar
  62. Kümmel S, Thomas A, Jeschke S et al. (2006) Postoperative therapy modalities for cervical carcinoma. Anticancer Res 26:1707–1714PubMedGoogle Scholar
  63. Kumar L, Kaushal R, Nandy M et al. (1994) Chemotherapy followed by radiotherapy versus radiotherapy alone in locally advanced cervical cancer: a randomized study. Gynecol Oncol 54:307–315PubMedGoogle Scholar
  64. Lochmüller H (1983) Zur Strahlentherapie bei der Behandlung des Vulvakarzinoms. Radiology 23:24–28Google Scholar
  65. Lovecchio JL, Averette HE, Donato D et al. (1989) Five-year survival of patients with periaortic nodal metastases in clinical stage IB and IIA cervical carcinoma. Gynecol Oncol 34:43–51PubMedGoogle Scholar
  66. Malfetano J, Keys H, Kredentser D et al. (1993) Weekly cisplatin and radical radiation therapy for advanced, recurrent, and poor prognosis cervical carcinoma. Cancer 71:3703–3706PubMedGoogle Scholar
  67. Mock U, Kucera H, Fellner C, Knocke TH, Potter R (2003) High-dose-rate (HDR) brachytherapy with or without external beam radiotherapy of primary vaginal carcinoma: longterm results and side effects. Int J Radiat Oncol Biol Phys 56:950–957PubMedGoogle Scholar
  68. Monk BJ, Walker JL, Tewari K et al. (1994) Open interstitial brachytherapy for the treatment of local-regional recurrences of uterine corpus and cervix cancer after primary surgery. Gynecol Oncol 52:222–228PubMedGoogle Scholar
  69. Moore DH, Blessing JA, McQuellon RP et al. (2004) Phase III Study of Cisplatin with or without paclitaxel in stage IVb, recurrent, or persistant squamous cell carcinoma of the cervix: A gynecologic oncology group study. JCO 22:3113–3119Google Scholar
  70. Morris M, Eifel PJ, Lu J et al. (1999) Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancer. N Engl J Med 340:1137–1143PubMedGoogle Scholar
  71. Munstedt K, Johnson P, Bohlmann MK, Zygmunt M, von Georgi R, Vahrson H (2005) Adjuvant radiotherapy in carcinomas of the uterine cervix: the prognostic value of haemoglobin levels. Int J Gynecol Cancer 15:285–291PubMedGoogle Scholar
  72. Munstedt K, Johnson P, von Georgi R, Vahrson H, Tinneberg HR (2004) Consequences of inadvertent, suboptimal primary surgery in carcinoma of the uterine cervix. Gynecol Oncol 94:515–520PubMedGoogle Scholar
  73. Nolan JF, Dorough ME, Anson JH (1967) The value of preoperative radiation therapy in stage I carcinoma of the uterine corpus. Amer J Obstet Gynecol 98:663–674Google Scholar
  74. Nori D, Merimsky O, Batata M (1994) Postoperative high doserate intravaginal brachytherapy combined with external irradiation for early stage endometrial cancer: a long-term follow-up. Int J Rad Onc 30:831–837Google Scholar
  75. Nout RA et al. for the PORTEC Study Group (2010) Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2): an open-label, non-inferiority, randomised trial. The Lancet 375: 816–823Google Scholar
  76. Paton F, Paulden M, Saramago P et al. (2010) Topotecan for the treatment of recurrent and stage IVb carcinoma of the cervix. Health technol Assess Suppl 1: 55–62Google Scholar
  77. Pecorelli S (2009) für das „FIGO Committee on Gynecologic Oncology“ Revisted FIGO staging for carcinoma of the vulva, cervix and endometrium. Intern J Gynecol Obstet 105:103–104Google Scholar
  78. Perez C, Kao MS, Hederman MA (1987) Randomized study of preoperative radiation and surgery or irradiation alone in the treatment of stage IB and IIA carcinoma of the uterine cervix: final report. Gynecol Oncol 27:129–140PubMedGoogle Scholar
  79. Perez CA, Camel HM, Galakatos AE et al. (1988) Definitive irradiation in carcinoma of the vagina: long term evaluation of results. Int J Radiat Oncol Biol Phys 15:1283–1290PubMedGoogle Scholar
  80. Perez CA, Camel HM, Kuske RR et al. (1986) Radiation therapy alone in the treatment of carcinoma of the uterine cervix: A 20-year experience. Gynecol Oncol 23:127–140PubMedGoogle Scholar
  81. Perez CA, Grigsby PW, Camel HM et al. (1995) Irradiation alone or in combination with surgery in stage Ib, IIa, and IIb carcinoma of uterine cervix: update of a nonrandomized comparison. Int J Radiat Oncol Biol Phys 31:703–716PubMedGoogle Scholar
  82. Perez CA, Grigsby PW, Garipagaoglu M et al. (1999) Factors effecting long-term outcome of irradiation in carcinoma of the vagina. Int J Radiat Oncol Biol Phys 44:37–45PubMedGoogle Scholar
  83. Peters WA, Liu PY, Barrett RJ et al. (2000) Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix. J Clin Oncol 18:1606–1613PubMedGoogle Scholar
  84. Pettersson F (1995) Annual report on the results of the treatment in gynecologic cancer. Vol. 22, statements of results obtained in patients 1987–1989. inclusive actuarial survival up to 1993. Editoral Office Radium Hemmet, StockholmGoogle Scholar
  85. Pfleiderer A (1992) Die Operation beim Endometriumkarzinom. In: Ladner H-A, Pfleiderer A, Profous CZ (Hrsg) Gynäkologische Radiologie. Springer, Berlin Heidelberg New York Tokio, S 13–25Google Scholar
  86. Piver MS, Marchetti DL, Patton T et al. (1988) Radical hysterectomy and pelvic lymphadenectomy versus radiation therapy for small (⤠3 cm) stage Ib cervical carcinoma. AJCO 11:21–24PubMedGoogle Scholar
  87. Piver MS, Rutledge F, Smith JP (1974) Five classes of extended hysterectomy for women with cervical cancer. Obstet Gynecol 44:265–270PubMedGoogle Scholar
  88. Potish RA, Twiggs LB, Adcock LL et al. (1986) Effect of cis-platinum on tolerance to radiation therapy in advanced cervical cancer. Amer J Clin Oncol 9:387–391Google Scholar
  89. Price J, Hahn GA (1965) Vaginal involvement in endometrial carcinoma. Am J Obstet Gynecol 91:1060–1065PubMedGoogle Scholar
  90. Quinn MA, Campbell JJ (1989) Tamoxifen therapy in advanced/recurrent endometrial carcinoma. Gynecol Oncol 32:1–3PubMedGoogle Scholar
  91. Randall ME, Filiaci VL, Muss H et al. (2006) Randomized phase III trial of whole-abdominal irradiation versus doxorubicin and cisplatin chemotherapy in advanced endometrial cancer: A Gynecologic Oncology Group study. JCO 24:36–44Google Scholar
  92. Reed NS, et al. für: European Organisation for Research and Treatment of Cancer Gynaecological Cancer Group (2008) Phase III randomised study to evaluate the role of adjuvant pelvic radiotherapy in the treatment of uterine sarcomas stages I and II: an European Organisation for Research and Treatment of Cancer Gynaecological Cancer Group Study (protocol 55874). Eur J Cancer 44:808–818PubMedGoogle Scholar
  93. Rose PG, Bundy BN, Watkins EB et al. (1999) Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer. N Engl J Med 340:1144–1153PubMedGoogle Scholar
  94. Rotman M, Pajak TF, Choi K et al. (1995) Prophylactic extended-field irradiation of para-aortic lymph nodes in stages IIB and bulky IB and IIA cervical carcinomas: ten-year treatment results of RTOG 79–20. JAMA 274:387–393PubMedGoogle Scholar
  95. Rotte K (1975) Übersicht über die Afterloadingverfahren in der gynäkologischen Strahlentherapie. Strahlenther Onkol 150:237–242Google Scholar
  96. Runowicz CD, Wadler S, Rodrigues I et al. (1989) Concomittant cisplatin and radiotherapy in locally advanced cervical carcinoma. Gynecol Oncol 34:395–401PubMedGoogle Scholar
  97. Rush S, Lovecchio J, Gal D et al. (1992) Comprehensive management including interstitial brachytherapy for locally advanced or recurrent gynecologic malignancies. Gynecol Oncol 46:322–325PubMedGoogle Scholar
  98. Salazar OM, Feldstein ML, DePapp EW et al. (1977) Endometrial carcinoma: analysis of failures with special emphasis on the use of initial preoperative external beam radiation. Int J Radiat Oncol Biol Phys 2:1101–1107PubMedGoogle Scholar
  99. Scherer E, Sack H (1996) Strahlentherapie. Radiologische Onkologie. Springer, Berlin Heidelberg New York TokioGoogle Scholar
  100. Schreer I (1997) Primary irradiation. In: Vahrson HW (ed) Radiation oncology of gynecologic cancers. Springer, Berlin Heidelberg New York Tokio, pp 82–86Google Scholar
  101. Sedlis A, Bundy BN, Rotman MZ et al. (1999) A randomized trial of pelvic radiation therapy versus no further therapy in selected patients with stage IB carcinoma of the cervix after radical hysterectomy and pelvic lymphadenectomy: A Gynecologic Oncology Group Study. Gynecol Oncol 73:177–183PubMedGoogle Scholar
  102. Seegenschmiedt MH (1998) Nebenwirkungen in der Onkologie. Springer, Berlin Heidelberg New York TokioGoogle Scholar
  103. Singh AK, Grigsby PW, Rader JS, Mutch DG, Powel MA (2005) Cervix carcinoma, concurrent chemoradiation, and salvage of isolated paraaortic lymph node recurrence. Int J Radiat Oncol Biol Phys 61:450–455PubMedGoogle Scholar
  104. Shueng PW, Hsu WL, Jen YM et al. (1998) Neoadjuvant chemotherapy followed by radiotherapy should not be a standard for locally advanced cervical cancer. Int J Radiat Oncol Biol Phys 40:889–896PubMedGoogle Scholar
  105. Smit BJ, Du Troit JP, Groenewald WA (1989) An indwelling intra-uterine tube to facilitate high dose rate intra-cavitary therapy for carcinoma of the cervix. Br J Radiol 62:68–69PubMedGoogle Scholar
  106. Sorbe B, Kjellgren O, Stenson S (1990) Prognosis of endometrial carcinoma stage I in two Swedish regions. A study with special regard to the effects of intracavitary irradiation with high dose-rate afterloading technique or with low dose-rate radium. Acta Oncol 29:29–37PubMedGoogle Scholar
  107. Souhami L, Gill R, Allan S et al. (1991) A randomized trial of chemotherapy followed by pelvic radiation therapy in stage IIIb carcinoma of the cervix. Int J Radiat Oncol Biol Phys 9:970–997Google Scholar
  108. Souhami L, Seymour R, Roman TN et al. (1993) Weekly cisplatin plus external beam radiotherapy and high dose rate brachytherapy in patients with locally advanced carcinoma of the cervix. Int J Radiat Oncol Biol Phys 27:871–878PubMedGoogle Scholar
  109. Stehman FB, Bundy BN, Thomas G (1993) Hydroxyurea versus misonidazole with radiation in cervical carcinoma: longterm follow-up of a Gynecologic Oncology Group trial. J Clin Oncol 11:1523–1528PubMedGoogle Scholar
  110. Stock RG, Chen AS, Flickinger JC et al. (1995) Node-positive cervical cancer: impact of pelvic irradiation and pattern of failure. Int J Radiat Oncol Biol Phys 31:31–36PubMedGoogle Scholar
  111. Stock RG, Chen AS, Seski J (1995) A 30-year experience in the management of primary carcinoma of the vagina: analysis of prognostic factors and treatment modalities. Gynecol Oncol 56:45–52PubMedGoogle Scholar
  112. Tan R, Chung CH, Liu MT et al. (1991) Radiotherapy for postoperative recurrent uterine cervical carcinoma. Acta Oncol 30:353–356PubMedGoogle Scholar
  113. Tattersall MHN, Lorvidhaya V, Vootiprux A (1995) Randomized trial of epirubicin and cisplatin chemotherapy followed by pelvic radiation in locally advanced cervical cancer. J Clin Oncol 13:444–451PubMedGoogle Scholar
  114. Tran PT, Su Z, Hara W et al. (2007) Long-term survivors using intraoperative radiotherapy for recurent gynecologic malignancies. IJROBP 69: 504–511Google Scholar
  115. Vahrson H (1982) Die radiologische Behandlung unter Einschluss der Instillationstherapie. In: Zander J (Hrsg) Ovarialkarzinom. Urban & Schwarzenberg, München Wien, S 88–99Google Scholar
  116. Vahrson HW (1997) Postoperative irradiation in primary epithelial ovarian cancer. In: Vahrson HW (ed) Radiation oncology of gynecologic cancers. Springer, Berlin Heidelberg New York Tokio, pp 320–334Google Scholar
  117. Vavra N, Seifert M, Kucera H et al. (1991) Die Strahlentherapie des primären Vaginalkarzinoms und der Einfluß histologischer und klinischer Faktoren auf die Prognose. Strahlenth Onc 167:1–6Google Scholar
  118. Wade MD, Kohorn EI, Morris JM (1967) Adenocarcinoma of the endometrium. Am J Obstet Gynecol 99:867Google Scholar
  119. Wang X, Liu R, Ma R et al. (2010) High dose rate versus low dose rate brachytherapy for locally advanced uterine cervix cancer. Cochrane Database Syste RevGoogle Scholar
  120. Way S (1960) Carcinoma of the vulva. Am J Obstet Gynecol 0:692Google Scholar
  121. Whitney CW, Sause W, Bundy BN et al. (1999) Randomized comparison of fluorouracil plus cisplatin versus hydroxyurea as an adjunct to radiation therapy in stage IIB-IVA carcinoma of the cervix with negative para-aortic lymph nodes: a Gynecologic Oncology Group and Southwest Oncology Group study. J Clin Oncol 17:1339–1348PubMedGoogle Scholar
  122. Wittekind C, Meyer H-J (2010) TNM Klassifikation maligner Tumoren. UICC 7. Auflage. Wiley-Blackwell WeinheimGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • J. Bahnsen
    • 1
  • G. Hänsgen
    • 2
  • W. Harms
    • 3
  1. 1.Klinik für RadioonkologieJohanniter-KrankenhausStendalDeutschland
  2. 2.SalzmündeDeutschland
  3. 3.RadioonkologieSt. Clara SpitalBaselSwitzerland

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