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Hematopoietic Stem Cell Transplantation

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Book cover Pediatric Oncology Nursing

Part of the book series: Pediatric Oncology ((PEDIATRICO))

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Abstract

The purpose of hematopoietic stem cell transplantation (HSCT) is to replace diseased, damaged, or absent hematopoietic stem cells (HSCs) with healthy HSCs. In general, allogeneic transplants are used when the hematopoietic stem cells are diseased (e.g., leukemia), damaged (e.g., sickle cell disease), or absent (e.g., severe immunodeficiency disease). Autologous transplants are used to provide stem cell rescue after higher doses of chemotherapy or radiation therapy, for example, in the treatment of solid tumors.

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Norville, R., Tomlinson, D. (2010). Hematopoietic Stem Cell Transplantation. In: Tomlinson, D., Kline, N.E. (eds) Pediatric Oncology Nursing. Pediatric Oncology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-87984-8_11

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