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Springer Handbook of Enzymes pp 89–125Cite as

Phosphorylase kinase

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References

  1. Hunter, T.: Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling. Cell, 80, 225–236 (1995)

    PubMed  CAS  Google Scholar 

  2. Kemp, B.E.; Parker, M.W.; Hu, S.; Tiganis, T.; House, C.: Substrate and pseudosubstrate interactions with protein kinases: determinants of specificity. Trends Biochem. Sci., 19, 440–444 (1994)

    PubMed  CAS  Google Scholar 

  3. Johnson, L.N.; Noble, M.E.M.; Owen, D.J.: Active and inactive protein kinases: structural basis for regulation. Cell, 85, 149–158 (1996)

    PubMed  CAS  Google Scholar 

  4. Kemp, B.E.; Pearson, R.B.; House, M.: Pseudosubstrate-based peptide inhibitors. Methods Enzymol., 201, 287–304 (1991)

    PubMed  CAS  Google Scholar 

  5. Adams, J.A.: Kinetic and catalytic mechanisms of protein kinases. Chem. Rev., 101, 2271–2290 (2001)

    PubMed  CAS  Google Scholar 

  6. da Cruz e Silva, E.F.; Cohen, P.T.: Isolation and sequence analysis of a cDNA clone encoding the entire catalytic subunit of phosphorylase kinase. FEBS Lett., 220, 36–42 (1987)

    PubMed  Google Scholar 

  7. Dasgupta, M.; Blumenthal, D.K.: Characterization of the regulatory domain of the γ-subunit of phosphorylase kinase. The two noncontiguous calmodulin-binding subdomains are also autoinhibitory. J. Biol. Chem., 270, 22283–22289 (1995)

    PubMed  CAS  Google Scholar 

  8. Dasgupta, M.; Honeycutt, T.; Blumenthal, D.K.: The γ-subunit of skeletal muscle phosphorylase kinase contains two noncontiguous domains that act in concert to bind calmodulin. J. Biol. Chem., 264, 17156–17163 (1989)

    PubMed  CAS  Google Scholar 

  9. Lowe, E.D.; Noble, M.E.; Skamnaki, V.T.; Oikonomakos, N.G.; Owen, D.J.; Johnson, L.N.: The crystal structure of a phosphorylase kinase peptide substrate complex: kinase substrate recognition. EMBO J., 16, 6646–6658 (1997)

    PubMed  CAS  Google Scholar 

  10. Owen, D.J.; Noble, M.E.; Garman, E.F.; Papageorgiou, A.C.; Johnson, L.N.: Two structures of the catalytic domain of phosphorylase kinase: an active protein kinase complexed with substrate analogue and product. Structure, 3, 467–482 (1995)

    PubMed  CAS  Google Scholar 

  11. Reimann, E.M.; Titani, K.; Ericsson, L.H.; Wade, R.D.; Fischer, E.H.; Walsh, K.A.: Homology of the γ subunit of phosphorylase b kinase with cAMP-dependent protein kinase. Biochemistry, 23, 4185–4192 (1984)

    PubMed  CAS  Google Scholar 

  12. Bender, P.K.; Emerson, C.P., Jr.: Skeletal muscle phosphorylase kinase catalytic subunit mRNAs are expressed in heart tissue but not in liver. J. Biol. Chem., 262, 8799–8805 (1987)

    PubMed  CAS  Google Scholar 

  13. Chamberlain, J.S.; Van Tuinen, P.; Reeves, A.A.; Philip, B.A.; Caskey, C.T.: Isolation of cDNA clones for the catalytic γ subunit of mouse muscle phosphorylase kinase: expression of mRNA in normal and mutant Phk mice. Proc. Natl. Acad. Sci. USA, 84, 2886–2890 (1987)

    PubMed  CAS  Google Scholar 

  14. Maichele, A.J.; Farwell, N.J.; Chamberlain, J.S.: A B2 repeat insertion generates alternate structures of the mouse muscle γ-phosphorylase kinase gene. Genomics, 16, 139–149 (1993)

    PubMed  CAS  Google Scholar 

  15. Hanks, S.K.: Homology probing: identification of cDNA clones encoding members of the protein-serine kinase family. Proc. Natl. Acad. Sci. USA, 84, 388–392 (1987)

    PubMed  CAS  Google Scholar 

  16. Cawley, K.C.; Akita, C.G.; Angelos, K.L.; Walsh, D.A.: Characterization of the gene for rat phosphorylase kinase catalytic subunit. J. Biol. Chem., 268, 1194–1200 (1993)

    PubMed  CAS  Google Scholar 

  17. Cawley, K.C.; Ramachandran, C.; Gorin, F.A.; Walsh, D.A.: Nucleotide sequence of cDNA encoding the catalytic subunit of phosphorylase kinase from rat soleus muscle. Nucleic Acids Res., 16, 2355–2356 (1988)

    PubMed  CAS  Google Scholar 

  18. Burwinkel, B.; Shiomi, S.; Al Zaben, A.; Kilimann, M.W.: Liver glycogenosis due to phosphorylase kinase deficiency: PHKG2 gene structure and mutations associated with cirrhosis. Hum. Mol. Genet., 7, 149–154 (1998)

    PubMed  CAS  Google Scholar 

  19. Hanks, S.K.: Messenger ribonucleic acid encoding an apparent isoform of phosphorylase kinase catalytic subunit is abundant in the adult testis. Mol. Endocrinol., 3, 110–116 (1989)

    PubMed  CAS  Google Scholar 

  20. Maichele, A.J.; Burwinkel, B.; Maire, I.; Sovik, O.; Kilimann, M.W.: Mutations in the testis/liver isoform of the phosphorylase kinase γ subunit (PHKG2) cause autosomal liver glycogenosis in the gsd rat and in humans. Nat. Genet., 14, 337–340 (1996)

    PubMed  CAS  Google Scholar 

  21. Calalb, M.B.; Fox, D.T.; Hanks, S.K.: Molecular cloning and enzymatic analysis of the rat homolog of “PhK-γ T”, an isoform of phosphorylase kinase catalytic subunit. J. Biol. Chem., 267, 1455–1463 (1992)

    PubMed  CAS  Google Scholar 

  22. Wehner, M.; Kilimann, M.W.: Human cDNA encoding the muscle isoform of the phosphorylase kinase γ subunit (PHKG1). Hum. Genet., 96, 616–618 (1995)

    PubMed  CAS  Google Scholar 

  23. Bahri, S.M.; Chia, W.: DPhK-γ, a putative Drosophila kinase with homology to vertebrate phosphorylase kinase γ subunits: molecular characterisation of the gene and phenotypic analysis of loss of function mutants. Mol. Gen. Genet., 245, 588–597 (1994)

    PubMed  CAS  Google Scholar 

  24. Kawai, J.; Shinagawa, A.; Shibata, K.; Yoshino, M.; Itoh, M.; et al.: Functional annotation of a full-length mouse cDNA collection. Nature, 409, 685–690 (2001)

    PubMed  Google Scholar 

  25. Krebs, E.G.; Fischer, E.H.: Phosphorylase b-to-a converting enzyme of rabbit skeletal muscle. Biochim. Biophys. Acta, 20, 150–157 (1956)

    PubMed  CAS  Google Scholar 

  26. Rall, T.W.; Wosilait, W.D.; Sutherland, E.W.: Interconversion of phosphorylase a and phosphorylase b from dog heart muscle. Biochim. Biophys. Acta, 20, 69–76 (1956)

    PubMed  CAS  Google Scholar 

  27. Krebs, E.G.; Love, D.S.; Bratvold, G.E.; Trayser, K.A.; Meyer, W.L.; Fischer, E.H.: Purification and properties of rabbit skeletal muscle phosphorylase b kinase. Biochemistry, 3, 1022–1033 (1964)

    PubMed  CAS  Google Scholar 

  28. Meyer, W.L.; Fischer, E.H.; Krebs, E.G.: Activation of skeletal muscle phosphorylase b kinase by calcium ion. Biochemistry, 3, 1033–1039 (1964)

    PubMed  CAS  Google Scholar 

  29. Graves, D.J.; Hayakawa, T.; Horvitz, R.A.; Beckman, E.; Krebs, E.G.: Studies on the subunit structure of trypsin-activated phosphorylase kinase. Biochemistry, 12, 580–585 (1973)

    PubMed  CAS  Google Scholar 

  30. Hayakawa, T.; Perkins, J.P.; Walsh, D.A.; Krebs, E.G.: Physiochemical properties of rabbit skeletal muscle phosphorylase kinase. Biochemistry, 12, 567–573 (1973)

    PubMed  CAS  Google Scholar 

  31. Hayakawa, T.; Perkins, J.P.; Krebs, E.G.: Studies of the subunit structure of rabbit skeletal muscle phosphorylase kinase. Biochemistry, 12, 574–580 (1973)

    PubMed  CAS  Google Scholar 

  32. Tu, J.I, Graves, D.J.: Inhibition of the phosphorylase kinase catalyzed reaction by glucose-6-P. Biochem. Biophys. Res. Commun., 53, 59–65 (1973)

    PubMed  CAS  Google Scholar 

  33. Yeoman, S.J.; Cohen, P.: The hormonal control of activity of skeletal muscle phosphorylase kinase. Phosphorylation of the enzyme at two sites in vivo in response to adrenalin. Eur. J. Biochem., 51, 93–104 (1975)

    Google Scholar 

  34. Pickett-Gies, C.A.; Walsh, D.A.: Phosphorylase kinase. The Enzymes, 3rd. Ed. (Boyer, P.D., Krebs, E.G., eds.), 17, 395–456 (1986)

    Google Scholar 

  35. Kilimann, M.; Heilmeyer, L.M.G.: The effect of Mg2+ on the Ca2+-binding properties of non-activated phosphorylase kinase. Eur. J. Biochem., 73, 191–197 (1977)

    PubMed  CAS  Google Scholar 

  36. Cohen, P.; Burchell, A.; Foulkes, J.G.; Cohen, P.T.W.; Vanaman, T.C.; Nairn, A.C.: Identification of the Ca2+-dependent modulator protein as the fourth subunit of rabbit skeletal muscle phosphorylase kinase. FEBS Lett., 92, 287–293 (1978)

    PubMed  CAS  Google Scholar 

  37. Sakai, K.; Matsumura, S.; Okimura, Y.; Yamamura, H.; Nishizuka, Y.: Liver glycogen phosphorylase kinase. Partial purification and characterization. J. Biol. Chem., 254, 6631–6637 (1979)

    PubMed  CAS  Google Scholar 

  38. Vandenheede, J.R.; De Wulf, H.; Merlevede, W.: Liver phosphorylase b kinase. Cyclic-AMP-mediated activation and properties of the partially purified rat-liver enzyme. Eur. J. Biochem., 101, 51–58 (1979)

    PubMed  CAS  Google Scholar 

  39. Carlson, G.M.; Bechtel, P.J.; Graves, D.J.: Chemical and regulatory properties of phosphorylase kinase and cyclic AMP-dependent protein kinase. Adv. Enzymol. Relat. Areas Mol. Biol., 50, 41–115 (1979)

    PubMed  CAS  Google Scholar 

  40. Cooper, R.H.; Sul, H.S.; McCullough, T.E.; Walsh, D.: Purification and properties of the cardiac isoenzyme of phosphorylase kinase. J. Biol. Chem., 255, 11794–11801 (1980)

    PubMed  CAS  Google Scholar 

  41. Skuster, J.R.; Chan, K.F.J.; Graves, D.J.: Isolation and properties of the catalytically active γ subunit of phosphorylase b kinase. J. Biol. Chem., 255, 2203–2210 (1980)

    PubMed  CAS  Google Scholar 

  42. Pocinwong, S.; Blum, H.; Malencik, D.; Fisher, E.H.: Phosphorylase kinase from dogfish skeletal muscle. Purification and properties. Biochemistry, 20, 7219–7226 (1981)

    PubMed  CAS  Google Scholar 

  43. Cohen, P.; Klee, C.B.; Picton, C.; Shenolikar, S.: Calcium control of muscle phosphorylase kinase through the combined action of calmodulin and troponin. Ann. N.Y. Acad. Sci., 356, 151–161 (1980)

    PubMed  CAS  Google Scholar 

  44. King, M.M.; Carslon, G.M.: Synergistic effect of Ca2+ and Mg2+ in promoting an activity of phosphorylase kinase that is insensitive to ethylene glycol bis (β-aminoethyl ether)-N,N-tetraacetic acid. Arch. Biochem. Biophys., 209, 517–523 (1981)

    PubMed  CAS  Google Scholar 

  45. King, M.M.; Carslon, G.M.: Synergistic activation by Ca2+ and Mg2+ as the primary cause for hysteresis in the phosphorylase kinase reactions. J. Biol. Chem., 256, 11058–11064 (1981)

    PubMed  CAS  Google Scholar 

  46. Chan, K.F.J.; Graves, D.J.: Rabbit skeletal muscle phosphorylase kinase. Catalytic and regulatory properties of the active α γ δ and γ δ complexes. J. Biol. Chem., 257, 5948–5955 (1982)

    PubMed  CAS  Google Scholar 

  47. Chan, K.F.J.; Graves, D.J.: Rabbit skeletal muscle phosphorylase kinase. Interactions between subunits and influence of calmodulin on different complexes. J. Biol. Chem., 257, 5956–5961 (1982)

    PubMed  CAS  Google Scholar 

  48. Chrisman, T.D.; Jordan, J.E.; Exton, J.H.: Purification of rat liver phosphorylase kinase. J. Biol. Chem., 257, 10798–10804 (1982)

    PubMed  CAS  Google Scholar 

  49. Kilimann, M.W.; Heilmeyer, L.M.G.: Multiple activities on phosphorylase kinase. 1. Characterization of three partial activities by their response to calcium ion, magnesium ion, pH, and ammonium chloride and effect of activation by phosphorylation and proteolysis. Biochemistry, 21, 1727–1734 (1982)

    PubMed  CAS  Google Scholar 

  50. Kilimann, M.W.; Heilmeyer, L.M.G.: Multiple activities on phosphorylase kinase. 2. Different specificities toward the protein substrates phosphorylase b, troponin, and phosphorylase kinase. Biochemistry, 21, 1735–1739 (1982)

    PubMed  CAS  Google Scholar 

  51. Chan, K.F.J.; Graves, D.J.: Isolation and physicochemical properties of active complexes of rabbit muscle phosphorylase kinase. J. Biol. Chem., 257, 5939–5947 (1982)

    PubMed  CAS  Google Scholar 

  52. Pohlig, G.; Wingender-Drissen, R.; Becker, J.U.: Characterization of phosphorylase kinase activities in yeast. Biochem. Biophys. Res. Commun., 114, 331–338 (1983)

    PubMed  CAS  Google Scholar 

  53. Picton, C.; Shenolikar, S.; Grand, R.; Cohen, P.: Calmodulin as an integral subunit of phosphorylase kinase from rabbit skeletal muscle. Methods Enzymol., 102, 219–227 (1983)

    PubMed  CAS  Google Scholar 

  54. Killilea, S.D.; Ky, N.M.: Purification and partial characterization of bovine heart phosphorylase kinase. Arch. Biochem. Biophys., 221, 333–342 (1983)

    PubMed  CAS  Google Scholar 

  55. Cohen, P.: Phosphorylase kinase from rabbit skeletal muscle. Methods Enzymol., 99, 243–250 (1983)

    PubMed  CAS  Google Scholar 

  56. Sul, H.S.; Dirden, B.; Angelos, K.L.; Hallenbeck, P.; Walsh, D.: Cardiac phosphorylase kinase: preparation and properties. Methods Enzymol., 99, 250–259 (1983)

    PubMed  CAS  Google Scholar 

  57. Chan, K.F.J.; Graves, D.J.: Separation of the subunits of muscle phosphorylase kinase. Methods Enzymol., 99, 259–267 (1983)

    PubMed  CAS  Google Scholar 

  58. Graves, D.J.: Use of peptide substrates to study the specificity of phosphorylase kinase phosphorylation. Methods Enzymol., 99, 268–278 (1983)

    PubMed  CAS  Google Scholar 

  59. Ashida, M.; Wyatt, G.R.: Properties and activation of phosphorylase kinase from silkmoth fat body. Insect Biochem. 9, 403–409 (1979)

    CAS  Google Scholar 

  60. Negami, A.; Sakai, K.; Kobayashi, T.; Tabuchi, H.; Nakamura, S.; Yamamura, H.: Two diverse effects of poly(L-lysine) on rabbit skeletal muscle phosphorylase kinase: stimulation of autophosphorylation and inhibition of its activity. FEBS Lett., 166, 335–338 (1984)

    PubMed  CAS  Google Scholar 

  61. Chrisman, F.D.; Sobo, G.E.; Exton, J.H.: The Mg2+ requirements of nonactivated and activated rat liver phosphorylase kinase. Inhibition of the activated form by free Mg2+. FEBS Lett., 167, 295–300 (1984)

    PubMed  CAS  Google Scholar 

  62. Crabb, J.W.; Heilmeyer, L.M.G.: High performance liquid chromatography purification and structural characterization of the subunits of rabbit muscle phosphorylase kinase. J. Biol. Chem., 259, 6346–6350 (1984)

    PubMed  CAS  Google Scholar 

  63. Srivastava, A.K.: Inhibition of phosphorylase kinase, and tyrosine protein kinase activities by quercetin. Biochem. Biophys. Res. Commun., 131, 1–5 (1985)

    PubMed  CAS  Google Scholar 

  64. Nikolaropoulos, S.; Sotiroudis, T.G.: Phosphorylase kinase from chicken gizzard. Partial purification and characterization. Eur. J. Biochem., 151, 467–473 (1985)

    PubMed  CAS  Google Scholar 

  65. Jennissen, H.P.; Petersen-von Gehr, J.K.H.; Botzet, G.: Activation and inhibition of phosphorylase kinase by monospecific antibodies against preparatively isolated α, β and γ subunits. Eur. J. Biochem., 147, 619–630 (1985)

    PubMed  CAS  Google Scholar 

  66. Andreeva, I.E.; Livanova, N.B.; Eronina, T.B.; Silonova, G.V.; Poglazov, B.F.: Phosphorylase kinase from chicken skeletal muscle. Quaternary structure, regulatory properties and partial proteolysis. Eur. J. Biochem., 158, 99–106 (1986)

    PubMed  CAS  Google Scholar 

  67. Kee, S.M.; Graves, D.J.: Properties of the γ subunit of phosphorylase kinase. J. Biol. Chem., 262, 9448–9453 (1987)

    PubMed  CAS  Google Scholar 

  68. Paudel, H.K.; Carlson, G.M.: Inhibition, of the catalytic subunit of phosphorylase kinase by its α/β subunits. J. Biol. Chem., 262, 11912–11915 (1987)

    PubMed  CAS  Google Scholar 

  69. Cox, D.E.; Meinke, M.H.; Edstrom, R.D.: Mechanism of calmodulin inhibition of cAMP-dependent protein kinase activation of phosphorylation kinase. Arch. Biochem. Biophys., 259, 350–362 (1987)

    PubMed  CAS  Google Scholar 

  70. Crabb, J.W.; Harris, W.R.; Johnson, C.M.; Sotiroudis, T.G.; Kuhn, C.C.; Heilmeyer, L.M.G.: Electrophoretic purification of the α and β subunits of phosphorylase kinase and evidence in support of the deduced amino acid sequences. Electrophoresis, 11, 133–140 (1990)

    PubMed  CAS  Google Scholar 

  71. Elliott, L.H.; Wilkinson, S.E.; Sedgwick, A.D.; Hill, C.H.; Lawton, G.; Davis, P.D.; Nixon, J.S.: K252a is a potent and selective inhibitor of phosphorylase kinase. Biochem. Biophys. Res. Commun., 171, 148–154 (1990)

    PubMed  CAS  Google Scholar 

  72. Farrar, Y.J.K.; Carlson, G.M.: Kinetic characterization of the calmodulinactivated catalytic subunit of phosphorylase kinase. Biochemistry, 30, 10274–10279 (1991)

    PubMed  CAS  Google Scholar 

  73. Beleta, J. Benedicto, P.; Gella, F.J.: Regulatory properties of rabbit liver phosphorylase kinase. Int. J. Biochem., 22, 453–460 (1990)

    PubMed  CAS  Google Scholar 

  74. Beleta, J.; Benedicto, P.; Aymerich, P.; Gella, F.J.: Purification and characterization of native and proteolytic forms of rabbit liver phosphorylase kinase. Int. J. Biochem., 22, 443–451 (1990)

    PubMed  CAS  Google Scholar 

  75. Eronina, T.B.; Andreeva, I.E.; Livanova, N.B.; Silonova, G.V.; Poglazov, B.F.: Regulatory properties and quaternary structure of chicken skeletal muscle phosphorylase kinase. Biol. Zentralbl., 107, 39–43 (1988)

    CAS  Google Scholar 

  76. Doorneweerd, D.D.; Tan, A.W.H.; Nuttall, F.Q.: Liver phosphorylase kinase: characterization of two interconvertible forms and partial purification of phosphorylase kinase a. Mol. Cell. Biochem., 47, 45–53 (1982)

    PubMed  CAS  Google Scholar 

  77. Paudel, H.K.; Carlson, G.M.: Functional and structural similarities between the inhibitory region of troponin I coded by exon VII and the calmodulin-binding regulatory region of the catalytic subunit of phosphorylase kinase. Proc. Natl. Acad. Sci. USA, 87, 7285–7289 (1990)

    PubMed  CAS  Google Scholar 

  78. Heilmeyer, L.M.G.: Molecular basis of signal integration in phosphorylase kinase. Biochim. Biophys. Acta, 1094, 168–174 (1991)

    PubMed  CAS  Google Scholar 

  79. Paudel, H.K.; Xu, Y.H.; Jarrett, H.W.; Carlson, G.M.: The model calmodulin-binding peptide melittin inhibits phosphorylase kinase by interacting with its catalytic center. Biochemistry, 32, 11865–11872 (1993)

    PubMed  CAS  Google Scholar 

  80. Lanciotti, R.A.; Bender, P.K.: Baculovirus-directed expression of the γ-subunit of phosphorylase kinase: purification and calmodulin dependence. Biochem. J., 299, 183–189 (1994)

    PubMed  CAS  Google Scholar 

  81. Cheng, A.; Fitzgerald, T.J.; Carlson, G.M.: Adenosine 5-diphosphate as an allosteric effector of phosphorylase kinase from rabbit skeletal muscle. J. Biol. Chem., 260, 2535–2542 (1985)

    PubMed  CAS  Google Scholar 

  82. Huang, C.Y.F.; Yuan, C.J.; Blumenthal, D.K.; Graves, D.J.: Identification of the substrate and pseudosubstrate binding sites of phosphorylase kinase γ-subunit. J. Biol. Chem., 270, 7183–7188 (1995)

    PubMed  CAS  Google Scholar 

  83. Lanciotti, R.A.; Bender, P.K.: The γ subunit of phosphorylase kinase contains a pseudosubstrate sequence. Eur. J. Biochem., 230 139–145 (1995)

    PubMed  CAS  Google Scholar 

  84. Owen, D.J.; Papageorgiou, A.C.; Garman, E.F.; Noble, M.E.M.; Johnson, L.N.: Expression, purification and crystallisation of phosphorylase kinase catalytic domain. J. Mol. Biol., 246, 374–381 (1995)

    PubMed  CAS  Google Scholar 

  85. Kee, S.M.; Graves, D.J.: Isolation and properties of the active γ subunit of phosphorylase kinase. J. Biol. Chem., 261, 4732–4737 (1986)

    PubMed  CAS  Google Scholar 

  86. Xu, Y.H.; Wilkinson, D.A.; Carlson, G.M.: Divalent cations but not other activators enhance phosphorylase kinases affinity for glycogen phosphorylase. Biochemistry, 35, 5014–5021 (1996)

    PubMed  CAS  Google Scholar 

  87. Rozi, A.; Jia, Y.: A theoretical study of effects of cytosolic Ca2+ oscillations on activation of glycogen phosphorylase. Biophys. Chem., 106, 193–202 (2003)

    PubMed  CAS  Google Scholar 

  88. Kumar, P.; Brushia, R.J.; Hoye, E.; Walsh, D.A.: Baculovirus-mediated over-expression of the phosphorylase b kinase holoenzyme and α γ δ and γ δ subcomplexes. Biochemistry, 43, 10247–10254 (2004)

    PubMed  CAS  Google Scholar 

  89. Burwinkel, B.; Hu, B.; Schroers, A.; Clemens, P.R.; Moses, S.W.; Shin, Y.S.; Pongratz, D.; Vorgerd, M.; Kilimann, M.W.: Muscle glycogenosis with low phosphorylase kinase activity: mutations in PHKA1, PHKG1 or six other candidate genes explain only a minority of cases. Eur. J. Hum. Genet., 11, 516–526 (2003)

    PubMed  CAS  Google Scholar 

  90. Shmelev, V.K.; Serebrenikova, T.P.; Nesterov, V.P.: Role of glycogen phosphorylase kinase in regulation of Ca2+-ATPase of sarcoplasmic reticulum of the common frog Rana temporaria. J. Evol. Biochem. Physiol., 40, 98–101 (2004)

    CAS  Google Scholar 

  91. Chebotareva, N.A.; Andreeva, I.E.; Makeeva, V.F.; Livanova, N.B.; Kurganov, B.I.: Effect of molecular crowding on self-association of phosphorylase kinase and its interaction with phosphorylase b and glycogen. J. Mol. Recognit., 17, 426–432 (2004)

    PubMed  CAS  Google Scholar 

  92. Hilder, T.L.; Carlson, G.M.; Haystead, T.A.; Krebs, E.G.; Graves, L.M.: Caspase-3 dependent cleavage and activation of skeletal muscle phosphorylase b kinase. Mol. Cell. Biochem., 275, 233–242 (2005)

    PubMed  CAS  Google Scholar 

  93. Priddy, T.S.; MacDonald, B.A.; Heller, W.T.; Nadeau, O.W.; Trewhella, J.; Carlson, G.M.: Ca2+-induced structural changes in phosphorylase kinase detected by small-angle X-ray scattering. Protein Sci., 14, 1039–1048 (2005)

    PubMed  CAS  Google Scholar 

  94. Nadeau, O.W.; Gogol, E.P.; Carlson, G.M.: Cryoelectron microscopy reveals new features in the three-dimensional structure of phosphorylase kinase. Protein Sci., 14, 914–920 (2005)

    PubMed  CAS  Google Scholar 

  95. Archila, S.; King, M.A.; Carlson, G.M.; Rice, N.A.: The cytoskeletal organizing protein Cdc42-interacting protein 4 associates with phosphorylase kinase in skeletal muscle. Biochem. Biophys. Res. Commun., 345, 1592–1599 (2006)

    PubMed  CAS  Google Scholar 

  96. Makeeva, V.F.; Chebotareva, N.A.; Andreeva, I.E.; Livanova, N.B.; Kurganov, B.I.: Interaction of phosphorylase kinase from rabbit skeletal muscle with flavin adenine dinucleotide. Biochemistry (Moscow), 71, 652–657 (2006)

    CAS  Google Scholar 

  97. Sijens, P.E.; Smit, G.P.; Borgdorff, M.A.; Kappert, P.; Oudkerk, M.: Multiple voxel 1H MR spectroscopy of phosphorylase-b kinase deficient patients (GSD IXa) showing an accumulation of fat in the liver that resolves with aging. J. Hepatol., 45, 851–855 (2006)

    PubMed  CAS  Google Scholar 

  98. Nadeau, O.W.; Anderson, D.W.; Yang, Q.; Artigues, A.; Paschall, J.E.; Wyckoff, G.J.; McClintock, J.L.; Carlson, G.M.: Evidence for the location of the allosteric activation switch in the multisubunit phosphorylase kinase complex from mass spectrometric identification of chemically crosslinked peptides. J. Mol. Biol., 365, 1429–1445 (2007)

    PubMed  CAS  Google Scholar 

  99. Wang, H.; Brautigan, D.L.: Peptide microarray analysis of substrate specificity of the transmembrane Ser/Thr kinase KPI-2 reveals reactivity with cystic fibrosis transmembrane conductance regulator and phosphorylase. Mol. Cell. Proteomics, 5, 2124–2130 (2006)

    PubMed  CAS  Google Scholar 

  100. Winchester, J.S.; Rouchka, E.C.; Rowland, N.S.; Rice, N.A.: In silico characterization of phosphorylase kinase: evidence for an alternate intronic polyadenylation site in PHKG1. Mol. Genet. Metab., 92, 234–242 (2007)

    PubMed  CAS  Google Scholar 

  101. Priddy, T.S.; Price, E.S.; Johnson, C.K.; Carlson, G.M.: Single molecule analyses of the conformational substates of calmodulin bound to the phosphorylase kinase complex. Protein Sci., 16, 1017–1023 (2007)

    PubMed  CAS  Google Scholar 

  102. Priddy, T.S.; Middaugh, C.R.; Carlson, G.M.: Electrostatic changes in phosphorylase kinase induced by its obligatory allosteric activator Ca2+. Protein Sci., 16, 517–527 (2007)

    PubMed  CAS  Google Scholar 

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(2009). Phosphorylase kinase. In: Schomburg, D., Schomburg, I., Chang, A. (eds) Springer Handbook of Enzymes. Springer Handbook of Enzymes, vol S4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-85701-3_3

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