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Cutaneous Lymphomas

  • Laura Y. McGirt
  • Matthias Steinhoff
Chapter
  • 849 Downloads

Core Messages

  • Cutaneous lymphomas are malignancies of the skin composed most commonly of aberrant lymphocytes from either a B or T-cell lineage. These lymphomas manifest in heterogenous clinical presentations, including the subtle eczematous patch to the more observable ulcerated nodules and tumors. There is also marked variation in morbidity and mortality, ranging from little to no effect on lifespan, to a devas-tatingly rapid progression to death. Numerous therapeutic options have become available in the last few decades, including extracorporeal photopheresis, monoclonal antibodies, and his-tone deacetylase inhibitors, and the choice of treatment is generally based upon the clinical staging and histologic diagnosis. Unfortunately, many of the more aggressive cutaneous lym-phomas will ultimately lead to death despite therapeutic intervention. In this chapter, we will focus on the clinical features, diagnosis, and management of primary cutaneous B and T-cell lymphomas.

Keywords

Mycosis Fungoides Cutaneous Lymphoma Denileukin Diftitox Lymphomatoid Papulosis Extracorporeal Photopheresis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  • Laura Y. McGirt
    • 1
  • Matthias Steinhoff
  1. 1.Department of DermatologyJohns Hopkins School of MedicineBaltimoreUSA

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