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Nuclear Medicine

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Imaging of Bone Tumors and Tumor-Like Lesions

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

Key Points

99mTechnechium labelled methylene diphosphonate (99mTc-MDP) bone scan:

• Detects bone metabolism

• Is a non-specific imaging modality

• Remains one of the primary investigations in the evaluation of bone malignancy

• May show patterns of disease or disease distribution which may help to confirm a diagnosis

• Should always be viewed in conjunction with other imaging modalities

Positron emission tomography (PET) in combination with CT (PET/CT):

• Has an undefined role in the management of bone sarcoma

• The primary lesion must be avid for 18Florine labelled floro-2-deoxy-d-glucose (FDG) or other radiopharmaceutical for the application of this modality

• Knowledge of the limitations and normal variants is necessary in order to avoid false positive results

• Sufficient time delay is necessary between imaging and previous surgery or radiotherapy to differentiate between recurrence and inflammatory reaction

• May have a future role in demonstrating response to therapy and as a prognostic indicator in the management of bone sarcoma

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Author information

Authors and Affiliations

  1. Radiology Department, Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, HA7 4LP, London, Middlesex, UK

    Ruth A. R. Green

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  1. Ruth A. R. Green
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Editor information

Editors and Affiliations

  1. MRI Department, Royal Orthopaedic Hospital, NHS Foundation Trust, Bristol Road South, Northfield, B31 2AP, Birmingham, UK

    A. Mark Davies

  2. Section of Musculoskeletal Radiology, Imaging Institute, Diagnostic Radiology/A21, School of Medicine of Case Western Reserve University, Cleveland Clinic Foundation, 9500 Euclid Ave., 44195, Cleveland, OH, USA

    Murali Sundaram

  3. Imaging Department, Royal Orthopaedic Hospital, NHS Foundation Trust, Bristol Road South, Northfield, B31 2AP, Birmingham, UK

    Steven L. J. James

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© 2009 Springer-Verlag Berlin Heidelberg

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Green, R. (2009). Nuclear Medicine. In: Davies, A., Sundaram, M., James, S. (eds) Imaging of Bone Tumors and Tumor-Like Lesions. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-77984-1_4

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  • DOI: https://doi.org/10.1007/978-3-540-77984-1_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-77982-7

  • Online ISBN: 978-3-540-77984-1

  • eBook Packages: MedicineMedicine (R0)

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