New Results on Energy Balance Analysis of Metabolic Networks

  • Qinghua Zhou
  • Simon C. K. Shiu
  • Sankar K. Pal
  • Yan Li
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 4815)


A central and long-standing objective of cellular physiology has been to understand the metabolic capabilities of living cells. In this paper, we perform optimization of metabolic networks in E.Coli under both flux and energy balance constraints. The impact of the energy balance is investigated on the behavior of metabolic networks. Different from the existing work, the preliminary results showed that the impact of imposing energy balance constraints on the biological metabolic systems is very limited.


Metabolic networks Flux Balance Analysis Energy Balance Analysis Constraint optimization 


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Copyright information

© Springer-Verlag Berlin Heidelberg 2007

Authors and Affiliations

  • Qinghua Zhou
    • 1
  • Simon C. K. Shiu
    • 2
  • Sankar K. Pal
    • 3
  • Yan Li
    • 1
  1. 1.College of Mathematics and Computer Science, Hebei University, Baoding City 071002, Hebei ProvinceChina
  2. 2.Department of Computing, The Hong Kong Polytechnic University, HungHom, KowloonHong Kong
  3. 3.Indian Statistical Institute, Kolkata 700 108India

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