Abstract
Disorders of glycerol metabolism include glycerol kinase deficiency and glycerol intolerance syndrome. Glycerol is a neutral, colorless liquid that can be detected in urine and blood. Analysis in urine is done by gas chromatography-mass spectrometry as performed for urine organic acid analysis as long as the sample is not treated with an ion exchange procedure. Glycerol in blood is detected by routine clinical chemistry labs. Alternative methods include an enzymatic based isotope dilution method and commercially available kits. It is important to avoid contaminants from lotions and suppositories. Enzyme activity assays and DNA testing are available although primarily on a research basis.
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© 2008 Springer-Verlag Berlin Heidelberg
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Dipple, K., McCabe, E. (2008). Glycerol and Glycerol Phosphates. In: Blau, N., Duran, M., Gibson, K. (eds) Laboratory Guide to the Methods in Biochemical Genetics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-76698-8_14
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DOI: https://doi.org/10.1007/978-3-540-76698-8_14
Publisher Name: Springer, Berlin, Heidelberg
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