Pädiatrie pp 1440-1445 | Cite as

Polio- und Leukodystrophien des Zentralnervensystems

  • F. Hanefeld

Auszug

Definition. Der Begriff Poliodystrophia cerebri progressiva (M. Alpers) umfasst eine Gruppe von Krankheiten der grauen Substanz, die basierend auf den Erstbeschreibungen von Alpers aus den Jahren 1931 und 1960 diese von den Leukodystrophien abgrenzen sollte. Es handelt sich also um akute Degenerationen der grauen Substanz, deren Ätiologie sehr heterogen ist. Die primäre Definition des Krankheitsbildes orientierte sich an der Degeneration der Neurone der grauen Substanz.

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Copyright information

© Springer Medizin Verlag Heidelberg 2007

Authors and Affiliations

  • F. Hanefeld
    • 1
  1. 1.Univ.-KinderklinikGöttingenGermany

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