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Lymph Nodes, Thymus, Spleen, and Lymphatics

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Abbreviations

AHS:

Adult health study samples

CTV:

Clinical target volumes

HSCT:

Hematopoetic stem cell transplantation

MLR:

Mixed lyphocyte reactions

NK:

Natural killer

PHA:

Phytohemagglutinin

TBI:

Total body irradiation

TLI:

Total lymphoid irradiation

References

  • Akiyama M, Yamakido M, Kobuka K, et al (1983) Peripheral lymphcyte response to PHA and T cell population among atomic bomb survivors. Radiat Res 93:572–580

    Google Scholar 

  • Akiyama M, Zhou OL, Kusunoki Y, et al (1989) Age and dose related alteration of in vitro mixed lymphcyte culture response of blood lymphocytes from A-bomb survivors. Radiat Res 117:26–34

    Google Scholar 

  • Akiyama M (1995) Late effects of radiation on the human immune system: an overview of immune response among the atomic-bomb survivors. Int J Radiat Biol 68(5):497–508

    Article  PubMed  CAS  Google Scholar 

  • Bloom ET, Akiyama M, Kom EL, et al (1988) Immunological responses of aging Japanese A-bomb survivors. Radiat Res 116:343–355

    Google Scholar 

  • Cao MD, Chen ZD, Xing Y (2004) Gamma irradiation of human dendritic cells influences proliferation and cytokine profile of T cells in autologous mixed lymphocyte reaction. Cell Biol Int 28(3):223–228

    Article  PubMed  CAS  Google Scholar 

  • Congdon CC (1966) The destructive effect of radiation on lymphatic tissue. Cancer Res 26(1):1211–1220

    PubMed  CAS  Google Scholar 

  • Cross AM, Leuchars E, Miller JFAP (1964) Studies on the recovery of the immune response in irradiated mice thymectomized in adult life. J Exp Med 119:837–850

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  • Dailey MO, Coleman CN, Fajardo LF (1981) Splenic injury caused by therapeutic irradiation. Am J Surg Pathol 5(4):325–331

    Article  PubMed  CAS  Google Scholar 

  • Doughty WE, Anderson RE, Yamamoto TT, Webber LS (1973) Spleen index in atomic bomb survivors. Arch pathol 96(6):395–398

    Google Scholar 

  • Engaset A (1964) Irradiation of lymph nodes and vessels. Oslo Universitetsforlaget

    Google Scholar 

  • Fujiwara S, Carter RL, Akiyama M, et al. (1994) Autoantibodies and immunoglobulins among atomic bomb survivors. Radiat Res 137:89–95

    Google Scholar 

  • Hall CB, Hall WJ, Ashley FW, Hamilton HB (1973) Immunoglobulin levels in atomic bomb survivors in Hiroshima Japan. Am J Epidemial 98:423–429

    Google Scholar 

  • Harrington NP, Chambers KA, Ross WM, Filion LG (1997) Radiation damage and immune suppression in splenic mononuclear cell populations. Clin Exp Immunol 107(2):417–424

    PubMed  CAS  PubMed Central  Google Scholar 

  • Harvey WG (1908) On the pathological effects of rontgen rays on animal tissues. J Pathol Bacteriol 12:U549–U123

    Google Scholar 

  • Hauer-Jensen M (1990) Late radiation injury of the small intestine—clinical, pathophysiologic and radiobiologic aspects. Acta Oncol 29(4):401–415

    Article  PubMed  CAS  Google Scholar 

  • Hayter CRR (1998) The clinic as laboratory: the case of radiation therapy, 1896–1920. Bull Hist Med 72(4):663–688

    Article  PubMed  CAS  Google Scholar 

  • Heineke H (1914) On the question of the effect of x-rays and radium on internal organs, particularly on the spleen. Dtsch Med Wochenschr 40:1311–1312

    Google Scholar 

  • Hektoen L (1915) The influence of the x-ray on the production of antibodies. J Infect Dis 17(2):415–422

    Article  CAS  Google Scholar 

  • King RA, Milton RC, Hamilton HB (1973) Serum immunoglobulin levels in the ABCC-JNIH Adult Health Study, Hiroshima—Nagasaki. At Bomb Casuality Commis Tech Rep 14–73

    Google Scholar 

  • Kusunoki Y, Akiyamam, Kyoizumi S, et al. (1986) Late effects of atomic bomb radiation on human immune response (2). Nagasaki Med J 61:340–344

    Google Scholar 

  • Kusunoki Y, Akigama M, Kyoizumi S, Bloom ET, Makinodan T (1988) Age-related alteration in the composition of immunocompetent blood cells in atomic bomb survivors. Int J Radiol Biol 53:19–198

    Google Scholar 

  • Kusunoki Y, Kgoizumi S, Hirai Y, et al. (1994) Late effects of atomic bomb radiation on human immune response (11). Flow cytometric analysis for subsets of T, B and NK cells in peripheral blood. J Hiroshima Med Assoc 97:25–29

    Google Scholar 

  • Murphy JB, Morton JJ (1915a) The lymphocyte as a factor in natural and induced resistance to transplanted cancer. Proc Natl Acad Sci USA 1:435–437

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  • Murphy JB, Morton JJ (1915b) The lymphocyte in natural and induced resistance to transplanted cancer: II. studies in lymphoid activity. J Exp Med 22(2):204–211

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  • Osterle SN, Norman JE (1981) Long term observation on absolute lymphocyte counts in the adult health study sample, Hiroshima and Nagasaki 1981 (book) published by the Radiation Effects Research Foundation RERF TR 10–79

    Google Scholar 

  • Pusey WA (1900) Lupus healed with roentgen rays report of case. J Am Med Assoc 35:1476–1478

    Article  Google Scholar 

  • Pusey WA (1902a) Report of cases treated with roentgen rays. J Am Med Assoc 38:911–919

    Article  Google Scholar 

  • Pusey WA (1902b) Cases of sarcoma and of Hodgkin’s disease treated by exposures to x-rays—a preliminary report. J Am Med Assoc 38:166–169

    Article  Google Scholar 

  • Pusey WA (1904) The treatment of leukemia and pseudo leukemia with roentgen rays. J Am Med Assoc 43:0273–0274

    Article  Google Scholar 

  • Pusey WA, Caldwell EW (1904) The practical application of the Rontgen rays in therapeutics and diagnosis WB Saunders Philadelphia, New York

    Google Scholar 

  • Ren HW, Shen JW, Tomiyama-Miyaji C et al (2006) Augmentation of innate immunity by low-dose irradiation. Cell Immunol 244(1):50–56

    Article  PubMed  CAS  Google Scholar 

  • Slavin S, Strober S, Fuks Z, Kaplan HS (1976) Long term survival of skin allografts in mice treated with fractionated total lymphoid irradiation. Science 193(4259):1252–1254

    Article  PubMed  CAS  Google Scholar 

  • Sung HK, Morisada T, Cho CH, Oike Y, Lee J, Sung EK, Chung JH, Suda T, Koh GY (2006) Intestinal and peri-tumoral lymphatic endothelial cells are resistant to radiation-induced apoptosis. Biochem Biophys Res Commun 345(2):545–551

    Article  PubMed  CAS  Google Scholar 

  • Taylor HD, Witherbee WD, Murphy JB (1919) Studies on x-ray effects. I. destructive action on blood cells. J Exp Med 29(1):53–73

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  • Thomas MM, Taylor HD, Witherbee WD (1919) Studies on x-ray effects. II. stimulative action on the lymphocytes. J Exp Med 29(1):75–82

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  • Usui Y, Okunuki Y, Hattori T et al (2006) Expression of costimulatory molecules on human retinoblastoma cells Y-79: Functional expression of CD40 and B7H1. Invest Ophthalmol Vis Sci 47(10):4607–4613

    Article  PubMed  Google Scholar 

  • Van den Brenk HAS (1957) The effect of ionizing radiation on the regeneration and behaviour of mammalian lymphatics. Am J Roentgenol 78:837–849

    Google Scholar 

  • Yao Z, Liu Y, Jones J, Strober S (2009) Differences in Bcl-2 expression by T-cell subsets alter their balance after in vivo irradiation to favor CD4 + Bcl-2hi NKT cells. Eur J Immunol 39(3):763–775

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  • Zweifach BW, Kivy-Rosenbery E (1965) Microcirculatory effects of whole-body X-irradiation and radiomimetic procedures. Am J Physiol 208:492–498

    PubMed  CAS  Google Scholar 

  • Zhang Shu-Xin (1999) An atlas of histology. Springer, New York, pp 337–339

    Book  Google Scholar 

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Correspondence to Susan J. Knox .

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Jones, J.C., Knox, S.J. (2014). Lymph Nodes, Thymus, Spleen, and Lymphatics. In: Rubin, P., Constine, L., Marks, L. (eds) ALERT • Adverse Late Effects of Cancer Treatment. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-75863-1_26

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  • DOI: https://doi.org/10.1007/978-3-540-75863-1_26

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  • Publisher Name: Springer, Berlin, Heidelberg

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