Abstract
One of the goals of bioengineers today is to answer the basic question of how individual cells, which together comprise an entire living being, communicate and interact with one another and the physical and chemical environment in which they reside. In this chapter, we will focus on the micro and nano technologies that have been used to investigate the regulation of cell functions by micro and nano features in matrix distribution, surface topography and three-dimensional (3D) microenvironment, and explore the technologies that can be applied to the fabrication of functional tissue constructs.
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References
Cao Y, Vacanti JP, Paige KT, Upton J, Vacanti CA (1997) Plast Reconstr Surg 100:297–302; discussion 303–304
Singhvi R, Kumar A, Lopez GP, Stephanopoulos GN, Wang DI, Whitesides GM, Ingber DE (1994) Science 264:696–698
Li Jeon N, Baskaran H, Dertinger SK, Whitesides GM, Van de Water L, Toner M (2002) Nat Biotechnol 20:826–830
Chen CS, Mrksich M, Huang S, Whitesides GM, Ingber DE (1997) Science 276:1425–1428
Thakar RG, Ho F, Huang NF, Liepmann D, Li S (2003) Biochem Biophys Res Commun 307:883–890
Jiang X, Bruzewicz DA, Wong AP, Piel M, Whitesides GM (2005) Proc Natl Acad Sci USA 102:975–978
Li S, Bhatia S, Hu YL, Shiu YT, Li YS, Usami S, Chien S (2001) Biorheology 38:101–108
Hsu S, Thakar R, Liepmann D, Li S (2005) Biochem Biophys Res Commun 337:401–409
Dertinger SK, Jiang X, Li Z, Murthy VN, Whitesides GM (2002) Proc Natl Acad Sci USA 99:12542–12547
Clark P, Britland S, Connolly P (1993) J Cell Sci 105(1):203–212
McBeath R, Pirone DM, Nelson CM, Bhadriraju K, Chen CS (2004) Dev Cell 6:483–495
Flaim CJ, Chien S, Bhatia SN (2005) Nat Methods 2:119–125
Huang NF, Patel S, Thakar RG, Wu J, Hsiao BS, Chu B, Lee RJ, Li S (2006) Nano Lett 6:537–542
Turner DC, Lawton J, Dollenmeier P, Ehrismann R, Chiquet M (1983) Dev Biol 95:497–504
Nakatsuji N, Johnson KE (1984) Nature 307:453–455
Curtis A, Wilkinson C (1999) Biochem Soc Symp 65:15–26
Balaban NQ, Schwarz US, Riveline D, Goichberg P, Tzur G, Sabanay I, Mahalu D, Safran S, Bershadsky A, Addadi L, Geiger B (2001) in Nat Cell Biol 3:466–472
Tan JL, Tien J, Pirone DM, Gray DS, Bhadriraju K, Chen CS (2003) Proc Natl Acad Sci USA 100:1484–1489
Park A, Wu B, Griffith LG (1998) J Biomater Sci Polym Ed 9:89–110
Albrecht DR, Underhill GH, Wassermann TB, Sah RL, Bhatia SN (2006) Nat Methods 3:369–375
Tan W, Desai TA (2003) Tissue Eng 9:255–267
Nelson CM, Vanduijn MM, Inman JL, Fletcher DA, Bissell MJ (2006) Science 314:298–300
Li D, Ouyang G, McCann JT, Xia Y (2005) Nano Lett 5:913–916
Yang F, Murugan R, Wang S, Ramakrishna S (2005) Biomaterials 26:2603–2610
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Patel, S., Lam, H., Li, S. (2008). Micro and Nano Patterning for Cell and Tissue Engineering. In: Artmann, G., Chien, S. (eds) Bioengineering in Cell and Tissue Research. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-75409-1_10
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DOI: https://doi.org/10.1007/978-3-540-75409-1_10
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-75408-4
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