Tumoren des Knochenmarkraumes

  • Jürgen Freyschmidt
  • Helmut Ostertag
  • Gernot Jundt

Zusammenfassung

Aus histogenetischer Sicht ist es heute nicht mehr gerechtfertigt, alle oben genannten Entitäten in einen Bezug zum Knochenmark zu bringen. Da sie jedoch aus klinisch-radiologischer oder topographischer Sicht und im Zusammenhang mit dem Generalthema „Knochentumoren“ primär überwiegend im Knochenmarkraum aufzutreten pflegen, handeln wir sie unter der Kapitelüberschrift „Tumoren des Knochenmarkraumes“ ab.

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Literatur

  1. Angervall L, Enzinger FM (1975) Extraskeletal neoplasm resembling Ewing’s sarcoma. Cancer 36: 240PubMedGoogle Scholar
  2. Bacci G, Picci P, Gitelis S et al. (1982) The treatment of localized Ewing’s-Sarcoma. Cancer 49:1561PubMedGoogle Scholar
  3. Ball J, Freedman L, Sissons HA (1977) Malignant round cell tumours of bone: An analytical histological study from the Cancer Research Campaign’s Bone Tumour Panel. Br J Cancer 36: 254PubMedGoogle Scholar
  4. Bator SM, Bauer TW, Marks KE et al. (1986) Periosteal Ewing’s sarcoma. Cancer 58:1781PubMedGoogle Scholar
  5. Bernstein M, Kovar H, Paulussen M et al. (2006) Ewing’s sarcoma family of tumors: current management. Oncologist 11: 503–519PubMedGoogle Scholar
  6. Bhagia SM, Grimer RJ, Davies AM et al. (1997) Ewing’s sarcoma presenting as a solitary bone cyst. Skeletal Radiol. 26: 722PubMedGoogle Scholar
  7. Carpentieri DF, Qualman SJ, Bowen J et al. (2005) Protocol for the examination of specimens from pediatric and adult patients with osseous and extraosseous Ewing Sarcoma Family of tumors, including Peripheral Primitive Neuroectodermal Tumor and Ewing Sarcoma. Arch Pathol Lab Med 129: 866PubMedGoogle Scholar
  8. Cavazzana AO, Miser JS, Jefferson J et al. (1987) Experimental evidence for a neural origin of Ewing’s sarcoma of bone. Am J Pathol 127:507PubMedGoogle Scholar
  9. Chan RC, Sutow WW, Lindberg RD (1979) Management and results of localized Ewing’s sarcoma. Cancer 43:1001PubMedGoogle Scholar
  10. Coombs RJ, Zeiss J, McCann K (1986) Multifocal Ewing’s tumor of the skeletal system. Skeletal Radiol 15: 254PubMedGoogle Scholar
  11. Coombs RJ, Zeiss J, Paley KJ et al. (1993) Ewing’s tumor of the proximal phalanx of the third finger with radiographic progression documented over a 6-year-period (case report 802). Skeletal Radiol 22: 460PubMedGoogle Scholar
  12. Dabbs DJ (2006) Diagnostic immunohistochemistry, 2nd edn. Churchill-Livigstone, OxfordGoogle Scholar
  13. Dahlin DC (1978) Bone tumors. Thomas, SpringfieldGoogle Scholar
  14. Dahlin DC, Coventry MD, Scanlow PV (1961) Ewing sarcoma. A critical analysis of 165 cases. J Bone Joint Surg (Am) 43:185–192Google Scholar
  15. Davies AM, Makwana NK, Grimer RJ et al. (1997) Skip metastasis in Ewing’s sarcoma: a report of three cases. Skeletal Radiology 26: 379PubMedGoogle Scholar
  16. de Alava E, A Kawai, J Healey et al. (1998) EWS-FLI1 fusion transcript structure is an independent determinant of prognosis in Ewing’s sarcoma [published erratum appears in J Clin Oncol 16: 2895]. J Clin Oncol 16:1248–1255PubMedGoogle Scholar
  17. Dehner LP (1993) Primitive neuroectodermal tumor and Ewing’s sarcoma. Am J Surg Pathol 17:1PubMedGoogle Scholar
  18. Ewing J (1921) Diffuse endothelioma of bone. Proc NY Pathol Soc 21: 17Google Scholar
  19. Ewing J (1939) A review of the classification of bone tumors. Surg Gynecol Obstet 68: 971Google Scholar
  20. Fletcher CDM, Unni KK, Mertens F (2002) Pathology and genetics of tumours of soft tissue and bone. IARC Press, LyonGoogle Scholar
  21. Friedrichs N, Kriegl L, Poremba C et al. (2006) Pitfalls in the detection of t(11;22) translocation by fluorescence in situ hybridization and RT-PCR: A single-blinded study. Diagn Molecular Pathol 15: 83–89Google Scholar
  22. Gasparini M, Fossati-Bellani F, Bonadonna G (1979) Current results with a combined treatment approach to localized Ewing’s sarcoma. Rec Results Cancer Res 68:45Google Scholar
  23. Göbel V, Jürgens H, Etspüler G et al. (1987) Prognostic significance of tumor volume in localized Ewing’s sarcoma of bone in children and adolescents. J Cancer Res Clin Oncol 113:187PubMedGoogle Scholar
  24. Hammoud S, Frassica FJ, McCarthy EF (2006) Ewing’s sarcoma presenting as a solitary cyst. Skeletal Radiology 35: 533PubMedGoogle Scholar
  25. Hartmann KR, Triche TJ, Kinsella TJ et al. (1991) Prognostic value of histopathology in Ewing’s sarcoma. Long-term follow-up of distal extremity primary tumors. Cancer 67:163Google Scholar
  26. Hindman BW, Gill HK, Zuppan CW (1997) Primitive neuroectodermal tuomor in a child with tuberous sclerosis. Skeletal Radiol 26:184PubMedGoogle Scholar
  27. Huvos A (1992) Bone tumors. Saunders, PhiladelphiaGoogle Scholar
  28. Jaffe HL (1958) Ewing’s sarcoma. In: Tumors and tumorous conditions of the bones and joints. Lea Febiger, Philadelphia, p 350Google Scholar
  29. Jaffe N, Traggis D, Salian S et al. (1976) Improved outlook for Ewing’s sarcoma with combination chemotherapy (Vincristine, Actinomycin D, and Cyclophosphamide) and radiation therapy. Cancer 38: 1925PubMedGoogle Scholar
  30. Johnson RE, Pomeroy TC (1975) Evaluation of therapeutic results in Ewing’s sarcoma. AJR 123: 583Google Scholar
  31. Jürgens H, Craft AW (1992) Studienprotokoll European Intergroup Cooperative Ewing’s sarcoma. Study EICESS 92Google Scholar
  32. Kenan S, Abdelwahab IF, Klein MJ et al. (1994) Periosteal Ewing’s sarcoma of the tibia (case report 819). Skeletal Radiol 23:59PubMedGoogle Scholar
  33. Kolar J, Zidkova H, Matejovsky Z et al. (1989) Periosteal Ewing’s sarcoma. RÖFO 150: 182Google Scholar
  34. Kovar H (2005) Context matters: The hen or egg problem in Ewing’s sarcoma. Seminars in Cancer Biology 15:189–196PubMedGoogle Scholar
  35. Levine E, Levine C (1983) Ewing tumor of rib: radiologic findings and computed tomography contribution. Skeletal Radiol 9: 227PubMedGoogle Scholar
  36. Lichtenstein L (1977) Bone tumors, 5th edn. Mosby, St. LouisGoogle Scholar
  37. Lipinski M, Braham K, Philip J et al. (1987) Neuroectodermal associated antigens on Ewing’s sarcoma cell lines. Cancer Res 47:183PubMedGoogle Scholar
  38. Llombart-Bosch A, Lacombe MJ, Peydro-Olaga A et al. (1988) Malignant peripheral neuroectodermal tumors of bone other than Askin’s neoplasm: Characterization of 14 new cases with immunhistiochemistry and electron microscopy. Virchows Arch Pathol [A]: 412–421Google Scholar
  39. Llombart-Bosch A, Peydro-Olaya A, Gomar F (1980) Ultrastructure of one Ewing’s sarcoma of bone with endothelial character and comparative review of the vessels in 27 cases of typical Ewing’s sarcoma. Path Res Pract 167: 71PubMedGoogle Scholar
  40. López-Terrada D (1994) Molecular genetics of small round cell tumors. Semin Diagn Pathol 13: 242Google Scholar
  41. Macintosh DJ, Price CHG, Jeffree GM (1975) Ewing’s tumour: a study of behaviour and treatment in fortyseven cases. J Bone Joint Surg [Br] 57: 331Google Scholar
  42. MacVicar AD, Olliff JFC, Pringle J et al. (1992) Ewing’s sarcoma: MR imaging of chemotherapy-induced changes with histologic correlation. Radiology 184: 859PubMedGoogle Scholar
  43. Mahoney JP, Balinger WE, Alexander RW (1978) So-called extraskeletal Ewing’s sarcoma. Am J Clin Pathol 70:926PubMedGoogle Scholar
  44. May WA, Gishizky ML, Lessnick SL et al. (1993) Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLU for transformation. Proc Nat Acad Sci USA 90: 5752–5756PubMedGoogle Scholar
  45. Meier VS, Kühne T, Jundt G et al. (1998) Molecular diagnosis of Ewing tumors: improved detection of EWS-FLI-1 and EWS-ERG chimeric transcripts and rapid determination of exon combinations. Diagn Mol Pathol 7: 29–35PubMedGoogle Scholar
  46. Mhawech-Fauceglia P, Herrmann FR, Bshara W et al. (2007) Friend leukaemia integration-1 expression in malignant and benign tumours: a multiple tumour tissue microarray analysis using polyclonal antibody. J Clin Pathol 60: 694–700PubMedGoogle Scholar
  47. Mirra JM (1989) Bone tumors. Lea Febiger, PhiladelphiaGoogle Scholar
  48. Nascimento AG, Unni KK, Pritchard PJ, Cooper KL, Dahlin DC (1980) Aclinicopathologic study of 20 cases of large cell (atypical) Ewing’s sarcoma of bone. Am J Surg Pathol 4: 29PubMedGoogle Scholar
  49. Noguera R (1996) Cytogenetics and tissue culture of small round cell tumors of bone and soft tissue. Semin Diagn Pathol 13:171PubMedGoogle Scholar
  50. Paulussen M, Craft AW, Lewis I et al. (2008) Results of the EICESS-92 Study: two randomized trials of Ewing’s sarcoma treatment — cyclophosphamide compared with ifosfamide in standard-risk patients and assessment of benefit of etoposide added to standard treatment in high-risk patients. J Clin Oncol 26:4385–4393PubMedGoogle Scholar
  51. Perez C, Razek A, Tefft M et al. (1977) Analyses of local tumor control in Ewing’s sarcoma. Cancer 40: 2864PubMedGoogle Scholar
  52. Petit C, Levilliers J, Weissenbach J (1988) Physical mapping of the human pseudo-autosomal region; comparison with genetic linkage map. Embo J 7: 2369–2376PubMedGoogle Scholar
  53. Pritchard DJ, Dahlin DC, Dauphine RT et al. (1975) Ewing’s sarcoma: a clinicopathological and statistical analysis of patients surviving five years or longer. J Bone Joint Surg [Am] 57:10Google Scholar
  54. Rettig NJ, Garin-Chesa P, Huvos AJ (1992) Ewing’s sarcoma: New approaches to histogenesis and molecular plasticity. Lab Invest 66: 133PubMedGoogle Scholar
  55. Riggi N, Stamenkovic I (2007) The biology of Ewing sarcoma. Cancer Letters 254: 1–10PubMedGoogle Scholar
  56. Roessner A (1984) Zur Zyto-and Histogenese der malignen und semimalignen Knochentumoren. Fischer, Stuttgart, S 99Google Scholar
  57. Roessner A, Jürgens H (1993) Neue Aspekte zur Pathologie des Ewing-Sarkoms. Osteoradiologie 2: 57Google Scholar
  58. Roessner A, Voss B, Rauterberg J, Immenkamp M, Grundmann E (1982) Biological characterization of human bone tumors. I. Ewing’s sarcoma. A comparative electron and immunofluorescence microscopy study. J Cancer Res Clin Oncol 104:171PubMedGoogle Scholar
  59. Rose JS, Hermann G, Mendelson DS et al. (1983) Extraskeletal Ewing’s sarcoma with computed tomography correlation. Skeletal Radiol 9:234PubMedGoogle Scholar
  60. Salzer-Kuntschik M, Delling G, Beron G et al. (1983) Morphological grades of regression in osteosarcoma after polychemotherapy — study COSS 80. J Cancer Res Clin Oncol 106 Suppl: 21PubMedGoogle Scholar
  61. Salzer-Kuntschik M, Wunderlich M (1971) Das Ewing-Sarkom in der Literatur: Kritische Studien zur histomorphologischen Definition und zur Prognose. Arch Orthop Unfallchir 71: 297PubMedGoogle Scholar
  62. Schajowicz F (1981, 1994) Tumors and tumorlike lesions of bone and joints. Springer, Berlin Heidelberg New YorkGoogle Scholar
  63. Schoedel K, Dickman PS, Krailo M et al. (1995) Histologic reponse to chemotherapy and prognosis in osseous Ewing’s sarcoma/primitive neuroectodermal tumor (ES/PNET) [Abstrakt]. Int J Surg Pathol 2 (Suppl): 443Google Scholar
  64. Schulz A, Jundt G, Alles JU et al. (1984) Ewing-Sarkom des Knochens. Pathologe 5: 63PubMedGoogle Scholar
  65. Shapeero LG, Vanel D, Sundaram M et al. (1994) Periostal Ewing’s sarcoma. Radiology 191:825PubMedGoogle Scholar
  66. Shirley SK, Gilula LA, Siegal GP et al. (1984) Roentgenographic-pathologic correlation of diffuse sclerosis in Ewing’s sarcoma of bone. Skeletal Radiol 12:69PubMedGoogle Scholar
  67. Spjut HJ, Dorfmann HD, Fechner RE et al. (1971) Tumors of bone and cartilage. In: Atlas of tumor pathology, fasc 5. Armed Forces Institute of Pathology, Washington, p 229Google Scholar
  68. Stevenson AJ, Chatten J, Bertoni F et al. (1994) CD 99 (p30/32MIC 2) Neuroectodermal/Ewing’s sarcoma antigen as an immunohistochemical marker. Review of more than 600 tumors and the literature experience. Appl Immunohistochem 2: 231Google Scholar
  69. Sundaram M, Inwards CY, Shives TE et al. (2005) Ewing’s sarcoma of the humerus mimicking fibrous dysplasia on imaging and biological behaviour. Skeletal Radiol 34: 285PubMedGoogle Scholar
  70. Swenson PC (1943) The roentgenologic aspects of Ewing’s tumor of bone marrow. AJR 50:343Google Scholar
  71. Triche T, Cavazzana A (1988) Round cell tumors of bone. In: Unni KK (ed) Bone tumors. Churchill Livingstone, Edinburgh, pp 199–224Google Scholar
  72. Turc-Carel C, Philip I, Berger MP et al. (1984) Chromosome study of Ewing’s sarcoma (ES) cell lines. Consistency of a reciprocal translocation t(11; 12) (q24; q12). Cancer Genet Cytogenet 12: 1PubMedGoogle Scholar
  73. Uehlinger E, Botsztejn C, Schinz HR (1942) Ewingsarkom und Knochenretikulosarkom: Klinik, Diagnose und Differentialdiagnose. Oncologia 1:193Google Scholar
  74. ürgens H, Exner U, Gadner H et al. (1988) Multidisciplinary treatment of Ewing’s sarcoma of bone. A 6-year experience of a European Cooperative Trial. Cancer 61: 23Google Scholar
  75. Vanel D, Contesso G, Couanet D et al. (1982) Computed tomography in the evaluation of 41 cases of Ewing’s sarcoma. Skeletal Radiol 9: 8PubMedGoogle Scholar
  76. Vlasak R, Sim FH (1996) Ewing’s sarcoma. Orthop Clin North Am 27: 591PubMedGoogle Scholar
  77. Vohra VG (1967) Roentgenmanifestations in Ewing’s sarcoma. Cancer 20: 727PubMedGoogle Scholar
  78. Weinstein JB, Siegel MJ, Griffith RC (1984) Spinal Ewing’s sarcoma: misleading appearances. Skeletal Radiol 11: 262PubMedGoogle Scholar
  79. Wooten WB, de Santos LA, Finkelstein JB (1978) Ewing tumor producing sclerosis of the left pedicle of the fourth vertebra. (Case report 64.) Skeletal Radiol 3: 65Google Scholar
  80. Woude HJ van der, Bloem JL, Holscher HC et al. (1994) Monitoring the effect of chemotherapy in Ewing’s sarcoma of bone with MR imaging. Skeletal Radiol 23:493PubMedGoogle Scholar
  81. Wuisman P, Roessner A, Blasius S et al. (1992) (Sub)peri-osteal Ewing’s sarcoma of bone. J Cancer Res Clin Oncol 118: 72PubMedGoogle Scholar
  82. Yamaguchi T, Tamai K, Saotome K et al. (1997) Ewing’s sarcoma of the thumb. Skeletal Radiol 26: 725PubMedGoogle Scholar
  83. Zoubek A, Dockhorn-Dworniczak B, Delattre O et al. (1996) Does expression of different EWS chimeric transcripts define clinically distinct risk groups of Ewing tumor patients? J Clin Oncol 14: 1245–1251PubMedGoogle Scholar
  84. Zucman J, Melot T, Desmaze C et al. (1993) Combinatorial generation of variable fusion proteins in the Ewing family of tumours. Embo J 12: 4481–4487PubMedGoogle Scholar

Literatur

  1. Ackerman L, van Drunen M, Reyes CV (1994) Malignant large cell lymphoma of sacrum (case report 836). Skeletal Radiol 23: 232PubMedGoogle Scholar
  2. Adams H, Tzankow A, d’Hondt S et al. (2008) Primary diffuse large B-cell lymphomas of the bone: prognostic relevance of protein expression and clinical factors. Hum Pathol 39:1323PubMedGoogle Scholar
  3. Bakshi NA, Ross CW, Finn WG et al. (2006) ALK-positive anaplastic large cell lymphoma with primary bone involvement in children. Am J Clin Pathol 125: 57PubMedGoogle Scholar
  4. Barbieri E, Cammelli S, Mauro F et al. (2004) Primary non-hodgkon’s lymphoma of the bone: Treatment and analysis of prognostic factors for stage I and Stage II. Int J Radiation Oncology Biol Phys 59: 760Google Scholar
  5. Beal K, Allen L, Yahalom J (2006) Primary bone lymphoma: Treatment results and prognostic factors with longterm follow-up of 82 patients. Cancer 106: 2652PubMedGoogle Scholar
  6. Boston HC Jr, Dahlin DC, Ivins JC et al. (1974) Malignant lymphoma (so-called reticulum cell sarcoma) of bone. Cancer 34: 1131PubMedGoogle Scholar
  7. Braunstein EM, White SJ (1980) Non-Hodgkin-Lymphoma of bone. Radiology 135:59PubMedGoogle Scholar
  8. Campbell SE, Filzen TW, Bezzant SM et al. (2003) Primary periosteal lymphoma: an unusual presentation of non-Hodgkin’s lymphoma with radiographic, MR imaging, and pathologic correlation. Skeletal Radiol 32: 231PubMedGoogle Scholar
  9. Chan JKC, Chi-Sing Ng, Pak-Kwan H et al. (1991) Anaplastic large cell Ki-1 lymphoma of bone. Cancer 68: 2186PubMedGoogle Scholar
  10. Dahlin DC (1978) Bone tumors, 3rd edn. Thomas, SpringfieldGoogle Scholar
  11. Dahlin DC, Unni KK (1986) Bone tumors: General aspects and data on 8542 cases, 4th edn. Thomas, Springfield, p 208Google Scholar
  12. Deshmukh C, Bakshi A, Parikh P (2004) Primary non-Hodgkin’s lymphoma of the bone. A single institution experience. Medical Oncology 21:263PubMedGoogle Scholar
  13. Dosoretz D, Raymond AK, Morphy GF et al. (1982) Primary lymphoma of bone. The relationship of morphologic diversity to clinical behavior. Cancer 50: 1009PubMedGoogle Scholar
  14. Dubey P, Ha CS, Besa PC et al. (1997) Localized primary malignant lymphoma of bone. Int J Radiation Oncology Biol Phys 37:1087Google Scholar
  15. Freyschmidt J (1986) Tumoren der Wirbelsäule und des Sakrums. In: Radiologische Diagnostik in Klinik und Praxis, Bd V/2. Thieme, StuttgartGoogle Scholar
  16. Freyschmidt J (2008) Knochenerkrankungen im Erwachsenenalter. Springer, Berlin Heidelberg New YorkGoogle Scholar
  17. Giudici MAI, Eggli KD, Moser RP et al. (1992) Malignant large cell lymphoma of tibial epiphysis (case report 730). Skeletal Radiol 21: 260PubMedGoogle Scholar
  18. Glotzbecker MP, Kersun LS, Choi JK et al. (2006) Primary Non-Hodgkin’s lymphoma of bone. J Bone Joint Surg Am 88-A: 583Google Scholar
  19. Hans CP, Weisenburger DD, Greiner TC et al. (2004) Confirmation of the molecular classification of diffuse large b-cell lymphoma by imunohistochemistry using a tissue microarray. Blood 103: 275PubMedGoogle Scholar
  20. Harris NL, Jaffe ES, Stein H et al. (1994) Revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group. Blood 84:1361PubMedGoogle Scholar
  21. Hermann G, Feldman F, Abdelwahab IF et al. (1991) Skeletal manifestations of granulocytic sarcoma (chloroma). Skeletal Radiol 20: 509PubMedGoogle Scholar
  22. Heyning FH, Hogendoorn PC, Kramer MH et al. (1999) Primary non-Hodgkin’s lymphoma of bone: a clinicopathological investigation of 60 cases. Leukemia 13: 2094PubMedGoogle Scholar
  23. Hillemanns M, McLeod RA, Unni KK (1996) Malignant lymphoma (case report). Skeletal Radiol 25: 73PubMedGoogle Scholar
  24. Jones D, Kraus MD, Dorfman DM (1999) Lymphoma presenting as a solitary bone lesion. Am J Clin Pathol 111: 171PubMedGoogle Scholar
  25. Kirsch J, llaslan H, Bauer TW et al. (2006) The incidence of imaging findings, and the distribution of skeletal lymphoma in a consecutive patient population seen over 5 years. Skeletal Radiol 35:590PubMedGoogle Scholar
  26. Kluin PM, Slootweg PJ, Schnurman HJ et al. (1984) Primary B-cell malignant lymphoma of the maxilla with a sarcomatous pattern and multilobated nuclei. Cancer 54: 1598PubMedGoogle Scholar
  27. Kremens B, Roessner A, Decking D (1982) Solitäre Knochenläsion als radiologische Erstmanifestation einer akuten lymphatischen Leukämie. Pädiatr Prax 26: 67Google Scholar
  28. Laufer L, Bernharroch D, Girges H et al. (1996) Pelvic granulocytic sarcoma. Skeletal Radiol 25: 693PubMedGoogle Scholar
  29. Lee HJ, Im JG, Goo JM (2003) Peripheral T-cell lymphoma: Spectrum of imaging findings with clinical and pathologic features. Radiographics 23: 7PubMedGoogle Scholar
  30. Lim MS, Huebner-Chan D, Fernandes B et al. (2001) An immunophenotypic and molecular study of primary large B-cell lymphoma of bone. Mod Pathol 14:1000PubMedGoogle Scholar
  31. Melamed JW, Martiez S, Hoffman O (1997) Imaging of primary multifocal osseous lymphoma. Skeletal Radiol 26: 35PubMedGoogle Scholar
  32. Mirra JM (1980) Bone tumors. Diagnosis and treatment. Lippincott, PhiladelphiaGoogle Scholar
  33. Moller MB, Pedersen NT, Christensen BE (2004) Diffuse large B-cell lymphoma: clinical implications of extranodal versus nodal presentation — a population-based study of 1575 cases. Brit J Haematology 124:151Google Scholar
  34. Ostrowski ML, Unni KK, Banks PM et al. (1986) Malignant lymphoma of bone. Cancer 58: 2646PubMedGoogle Scholar
  35. Pettit CK, Zukerberg LR, Gray MH et al. (1990) Primary lymphoma of bone. A B-cell neoplasma with a high frequency of multilobated cells. Am J Surg Pathol 14: 329PubMedGoogle Scholar
  36. Pires de Camargo O, Murias dos Santos Machado T, Croci AT et al. (2002) Primary bone lymphoma in 24 patients treated between 1955 and 1999. Clin Orthop Rel Res 397: 271Google Scholar
  37. Radaszkiewicz T, Hansmann M-L (1988) Primary high-grade malignant lymphomas of bone. Virchows Archiv [A] 413: 269Google Scholar
  38. Ramadan KM, Shenkier T, Sehn LH et al. (2007) A clinicopathological retrospective study of 131 patients with primary bone lymphoma: a population-based study of successively treated cohorts from the British Columbia Cancer Agency. Ann Oncol 18:129PubMedGoogle Scholar
  39. Roessner A (1984) Zur Zyto-und Histogenese der malignen und semimalignen Knochentumoren. Fischer, StuttgartGoogle Scholar
  40. Schajowicz F (1981, 1994) Tumors and tumorlike lesions of bone and joints. Springer, Berlin Heidelberg New YorkGoogle Scholar
  41. Spagnoli I, Gattoni F, Viganotti G (1982) Roentgenographic aspects of Non-Hodgkin-lymphomas presenting with osseous lesions. Skeletal Radiol 8: 39PubMedGoogle Scholar
  42. Stein H, Hummel M, Jöhrens K et al. (2007) Klassifikation und Pathogenese der malignen Lymphome. Internist 48: 351PubMedGoogle Scholar
  43. Swerdlow SH, Campo E, Harris NL et al. (2008) WHO classification of tumours of haematopoetic and lymphoid tissues, 4th edn. IARC Press, LyonGoogle Scholar
  44. Unni KK, Hogendoorn PC (2002) Malignant lymphoma. In: Fletcher CDM et al. (eds) Pathology & Genetics. Tumors of soft tissue and bone. IARC Press, LyonGoogle Scholar
  45. Vassallo J, Roessner A, Mellin W et al. (1986) Maligne Lymphome mit primärer Knochenmanifestation. Verh Dtsch Ges Pathol 70: 593Google Scholar
  46. Vermess M, Pearson KD, Einstein AB et al. (1972) Osseous manifestations of Waldenström’s macroglobulinemia. Radiology 102: 497PubMedGoogle Scholar
  47. Willis RB, Rozencwaig R (1996) Pediatric osteomyelitis masquerading as skeletal neoplasia. Orthop Clin North Am 27: 625PubMedGoogle Scholar

Literatur

  1. Aegerter E, Kirkpatrick JA (1975) Orthopedic diseases. Saunders, PhiladelphiaGoogle Scholar
  2. Angtuaco EJC, Fassas ABT, Walker R et al. (2004) Multiple myeloma: clinical review and diagnostic imaging. Radiology 231:11PubMedGoogle Scholar
  3. Baur A (2000) Diagnostik des Plasmozytoms mit der MRT. Radiologe 40: 716PubMedGoogle Scholar
  4. Baur A, Stäbler A, Bartl R et al. (1996) Infiltrationsmuster des Plasmozytoms in der Magnetresonanztomographie. Fortschr Röntgenstr 164:457Google Scholar
  5. Baur A, Stäbler A, Nagel D et al. (2002) Magnetic resonance imaging as a supplement for the clinical staging system of Durie and Salmon? Cancer 95: 1334PubMedGoogle Scholar
  6. Baur A, Stäbler S, Bartl R et al. (1997) MRI gadolinium enhancement of bone marrow: age-related changes in normals and in diffuse neoplastic infiltration. Skeletal Radiol 26:414PubMedGoogle Scholar
  7. Berenson JR, Lichtenstein A, Porter L et al. (1996) Efficacy of Pamidronate in reducing skeletal events in patients with advanced multiple myeloma. N Engl J Med 334:488PubMedGoogle Scholar
  8. Brandon C, Martel W, Weatherbee L et al. (1989) Osteosclerotic myeloma (POEMS syndrome). Skeletal Radiol 18: 542PubMedGoogle Scholar
  9. Dahlin DC (1978) Bone tumors, 3rd edn. Thomas, SpringfieldGoogle Scholar
  10. Dimopoulos MA, Barlogie B, Smith TL (1991) High serum lactate dehydrogenase level as a marker for drug resistance and short survival in multiple myeloma. Ann Intern Med 115: 931PubMedGoogle Scholar
  11. Doll G, Schaub T, Benning R (1992) Amyloidose des Knochens und der Weichteile nach einem Plasmozytom. RÖFO 156: 390PubMedGoogle Scholar
  12. Dooms GC, Fisher MR, Hricak H et al. (1985) Bone marrow imaging: magnetic resonance studies related to age and sex. Radiology 155: 429PubMedGoogle Scholar
  13. Durie BG (2003) A consensus report from the scientific advisors of the international myeloma foundation. Hematol J 4: 379–398PubMedGoogle Scholar
  14. Edelmann RR, Kaufmann H, Kolodny GM (1986) Case Report 350. Skeletal Radiol 15: 160Google Scholar
  15. Freyschmidt J (2008) Skeletterkrankungen. Klinisch-radiologische Diagnose und Differentialdiagnose, 3. Aufl. Springer, Heidelberg New York TokioGoogle Scholar
  16. Freyschmidt J, Freyschmidt G (1996) Haut-, Schleimhaut-und Skeletterkrankungen. SKIBO diseases. Springer, Berlin Heidelberg New York TokioGoogle Scholar
  17. Gleeeson TG, Moriarti J, Shortt CP et al. (2009) Accuracy of whole-body low-dose multidetector CT (WBLDCT) versus skeletal survey in the detection of myelomatous lesions, and correlation of disease distribution with whole-body MRI (WBMRI). Skeletal Radiol 38: 225Google Scholar
  18. Gompels BM, Votaw MC, Martel W (1972) Correlation of radiological manifestations of multiple myeloma with immunoglobulin abnormalities and prognosis. Radiology 104: 509PubMedGoogle Scholar
  19. Hall FM, Gore SM (1988) Osteosclerotic myeloma variants. Skeletal Radiol 17: 101PubMedGoogle Scholar
  20. Heiser S, Schwartzmann JJ (1952) Variations in the roentgen appearance of the skeletal system in myeloma. Radiology 58: 178PubMedGoogle Scholar
  21. Henschel MG, Freyschmidt J, Holland BR (1995) Experimentelle Untersuchungen zur Darstellbarkeit von Wirbelkörperspongiosa in der hochauflösenden Computertomographie. RÖFO 162: 269PubMedGoogle Scholar
  22. Hermann G, Abdelwahab IF, Berson BD (1990) Multiple myeloma (IgD) in a 28-year-old woman. Case report 621. Skeletal Radiol 19: 379PubMedGoogle Scholar
  23. Hermann G, Sherry H, Rabinowitz G (1981) Solitary plasmocytoma associated with peripheral neuropathy. Skeletal Radiol 6: 217PubMedGoogle Scholar
  24. Ishida T, Dorfman HD (1995) Plasma cell myeloma in unusually young patients: a report of two cases and review of the literature. Skeletal Radiol 24: 47PubMedGoogle Scholar
  25. Karasick D, Schweitzer ME, Miettinen M et al. (1996) Osseous metaplasia associated with amyloidproducing plasmocytoma of bone: a report of two cases. Skeletal Radiol 25: 263PubMedGoogle Scholar
  26. Kelly JJ, Kyle RA, Miles JM et al. (1983) Osteosclerotic myeloma and peripheral neuropathy. Neurology 33: 202PubMedGoogle Scholar
  27. Klein B, Wijdenes J, Zhang XG et al. (1991) Murine antiinterleukin-6 monoclonal antibody therapy for a patient with plasma cell leukemia. Blood 78: 1198PubMedGoogle Scholar
  28. Koppenfels R von (1972) Klinische Erfahrungen mit dem Plasmozytom unter besonderer Berücksichtigung der Röntgendiagnostik und der Strahlentherapie. Strahlentherapie 142: 276Google Scholar
  29. Krull R Hülsten H, Seeberg A et al. (1972) Klinische und röntgenologische Besonderheiten des solitären Plasmozytoms. RÖFO 117: 324Google Scholar
  30. Kyle RA (1975) Multiple myeloma. Review of 869 cases. Mayo Clin Proc 50:29PubMedGoogle Scholar
  31. Kyle RA, Maldonado JE, Bayrd ED (1974) Plasma cell leukemia. Report of 17 cases. Arch Intern Med 133: 813PubMedGoogle Scholar
  32. Lecouvet FE, Nayer P, Garbar C et al. (1998) Treated plasma cell lesions of bone with MRI signs of response to treatment: unexpected pathological findings. Skeletal Radiol 27: 692PubMedGoogle Scholar
  33. Lecouvet FE, van den Berg BC, Michaux L et al. (1998) Stage III multiple myeloma: clinical and prognostic value of spinal bone marrow MR imaging. Radiology 209: 653PubMedGoogle Scholar
  34. Libshitz HJ, Malthouse SR, Cunningham D et al. (1992) Multiple myeloma: appearance at MR imaging. Radiology 182: 833PubMedGoogle Scholar
  35. Morley JB, Schweiger AC (1967) The relation between chronic polyneuropathy and osteosclerotic myeloma. J Neurol Neurosurg Psychiatry 30: 432PubMedGoogle Scholar
  36. Moulopoulos LA, Dimopoulos MA, Alexanin R et al. (1994) Multiple myeloma: MR patterns of response to treatment. Radiology 193: 441PubMedGoogle Scholar
  37. Moulopoulos LA, Varma DGK, Dimopoulos MA et al. (1992) Multiple myeloma: spinal MR imaging in patients with untreated newly diagnosed disease. Radiology 185: 833PubMedGoogle Scholar
  38. Mulder JD, van Rijssel TG (1983) Case report 233. Skeletal Radiol 10:53PubMedGoogle Scholar
  39. Mundy GR, Raisz LG, Cooper RA et al. (1974) Evidence for the secretion of an osteoclast stimulation factor in myeloma. N Engl J Med 291: 1041PubMedGoogle Scholar
  40. Mundy GR, Rick ME, Furcotte R et al. (1978) Pathogenesis of hypercalcemia in lymphosarcoma cell leukemia. Role of an osteoclast activating factor like substance and mechanism of action for glucocorticoidtherapy. Am J Med 65: 600PubMedGoogle Scholar
  41. Read D, Warlow C (1978) Peripheral neuropathy and solitary plasmocytoma. J Neurol Neurosurg 41:177Google Scholar
  42. Reinus WR, Kyriakos M, Gilula LA et al. (1993) Plasma cell tumors with calcified amyloid deposition mistaken for chondrosarcoma. Radiology 189: 505PubMedGoogle Scholar
  43. Resnick D, Greenway GD, Bardwick PA (1981) Plasma-cell dyscrasia with polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes: the POEMS-syndrome. Radiology 140:17PubMedGoogle Scholar
  44. Schirmeister H et al. (2003) Positron emission tomography (PET) for staging of solitary plasmacytoma. Cancer Biother Radiopharm 18: 841Google Scholar
  45. Schmidt GP, Baur A, Stäbler A et al. (2005) Beurteilbarkeit diffuser Knochenmarkinfiltrationen der Wirbelsäule bei multiplem Myelom. Korrelation von MRT-Befunden mit der Histologie. Fortschr Röntgenstr 177: 745Google Scholar
  46. Sebes JJ, Niell HB, Palmien GMA et al. (1986) Skeletal surveys in multiple myeloma. Skeletal Radiol 15:354PubMedGoogle Scholar
  47. Snapper J, Kahn A (1971) Myelomatosis, fundamentals and clinical features. Univ Park Press, BaltimoreGoogle Scholar
  48. Spiro T, Freyschmidt J (1988) Zur Klinik und Radiologie des Plasmozytoms. — Analyse von 116 Fällen. RÖFO 148:516PubMedGoogle Scholar
  49. Stäbler A, Baur A, Bartl R et al. (1996) Contrast enhancement and quantitative signal analysis in MRI of multiple myeloma: assessment of focal and diffuse growth patterns in marrow correlated with biopsies and survival rates. Am J Radiol 167:1029Google Scholar
  50. Swiderski G, Bruszewski J (1972) Die röntgenologischen Veränderungen im Frühstadium des Wirbelsäulenmyeloms. Beitr Orthop 19: 623Google Scholar
  51. Tanaka O, Ohsawa T (1984) The POEMS-syndrome. Radiologe 24: 472PubMedGoogle Scholar
  52. Valderrama JAF, Bullough PG (1968) Solitary myeloma of the spine. J Bone Joint Surg [Br] 50: 82Google Scholar
  53. Voss S, Murphey M, Hall F (2001) Solitary osteosclerotic plasmacytoma: association with demyelinating polyneuropathy and amyloid deposition. Skeletal Radiol 30: 527PubMedGoogle Scholar
  54. Waldenström J (1970) Diagnosis and treatment of multiple myeloma. Grüne & Stratton, New YorkGoogle Scholar
  55. Wilner D (1982) Radiology of bone tumors and allied disorders. Saunders, PhiladelphiaGoogle Scholar

Literatur

  1. Abdelwahab IF, Klein MJ, Springfield DS et al. (2004) A solitary lesion of talus with mixed sclerotic and lytic changes: Rosai-Dorfman disease of 25 years duration. Skeletal Radiol 33: 230PubMedGoogle Scholar
  2. Foucar E, Rosai J, Dorfman RF (1990) Sinus histiocytosis with massive lymphadenopathy. Semin Diagn Pathol 7:19PubMedGoogle Scholar
  3. George J, Stacy G, Peabody T et al. (2003) Rosai-Dorfman disease manifesting as a solitary lesion of the radius in a 41-year-old woman. Skeletal Radiol 32: 236PubMedGoogle Scholar
  4. Lin J, Lazarus M, Wilbur A (1996) Sinus histiocytosis with massive lymphadenopathy: MRI findings of osseous lesions. Skeletal Radiology 25: 279PubMedGoogle Scholar
  5. McAlister WH, Herman T, Dehner LP (1990) Sinus histiocytosis with massive lymphadenopathy. Pediatr Radiol 20: 425PubMedGoogle Scholar
  6. Rosai J, Dorfman RF (1969) Sinus histiocytosis with massive lymphadenopathy. A newly recognized benign clinicopathological entity. Arch Pathol 87: 63PubMedGoogle Scholar
  7. Sartoris D, Resnick D (1986) Osseous involvement in sinus histiocytosis with massive lymphadenopathy. Eur J Pediatr 145: 238PubMedGoogle Scholar
  8. Sundaram C, Shantveer G, Chandrashekar V et al. (2005) Multifocal osseous involvement as the sole manifestation of Rosai-Dorfman disease. Skeletal Radiol 34: 658PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  • Jürgen Freyschmidt
    • 1
  • Helmut Ostertag
    • 2
  • Gernot Jundt
    • 3
  1. 1.Klinikum Bremen-Mitte gGmbHBeratungsstelle und Referenzzentrum für OsteoradiologieBremen
  2. 2.Klinikum Hannover NordstadtPathologisches InstitutHannover
  3. 3.Knochentumor-Referenzzentrum am Institut für Pathologieder Universität BaselBasel

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