Fungi are an extremely diverse group of organisms, with about 230,000 species distributed widely essentially in every ecosystem. Among them, only limited species are considered to be effective biocontrol agents. The fungal antagonists restrict the growth of plant pathogens by the three suggested mechanisms: antibiosis, competition and parasitism. Besides, they also induce the defense responses in host plants, termed “induced systemic resistance” (van Loon et al. 1998). Among the abovementioned mechanisms, antibiosis is considered the most important, in which the antagonists produce an array of secondary metabolites such as antibiotics and toxin, which contribute to the antagonistic activity of fungal biocontrol agents against plant pathogens. Antagonistic strains belonging to the Trichoderma and Fusarium genera were able to produce various secondary metabolites which can play a role in the mechanism of their biological activity (http://www.item.ba.cnr.it/biopesti.htm). Production of antimicrobial secondary metabolites has been reported in many fungal biocontrol agents (Gottlieb and Shaw 1970; Fries 1973; Hutchinson 1973; Sivasithamparam and Ghisalberti 1998; Vyas and Mathur 2002). In this review, we highlight the secondary metabolites of selected fungal biocontrol agents and their involvement in the control of plant pathogens.
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Mathivanan, N., Prabavathy, V.R., Vijayanandraj, V.R. (2008). The Effect of Fungal Secondary Metabolites on Bacterial and Fungal Pathogens. In: Karlovsky, P. (eds) Secondary Metabolites in Soil Ecology. Soil Biology, vol 14. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-74543-3_7
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