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Commentary

  • C. Max Schmidt
Chapter

Abstract

This commentary serves to: (1) draw attention to the importance of the chapter by Professor Buechler’s group; (2) reinforce the concept that identification and screening of patients with pancreatic cysts is a unique opportunity to prevent and cure pancreatic cancer through early detection and (3) review current management and anticipate future changes in management of these complex patients.

Keywords

Pancreatic Cancer Kras Mutation Cystic Neoplasm Pancreatic Cyst Mural Nodule 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. Cauley CE et al (2012) Outcomes of primary surveillance for intraductal papillary mucinous neoplasm. J Gastrointest Surg 16(2):258–67PubMedCrossRefGoogle Scholar
  2. Miller JR et al (2011) Outcome of the pancreatic remnant following segmental pancreatectomy for non-invasive intraductal papillary mucinous neoplasm. HPB (Oxford) 13(11):759–66. doi: 10.1111/j.1477-2574.2011.00354.x, Epub 2011 Sep 9CrossRefGoogle Scholar
  3. Ryu JK, Matthaei H, Dal Molin M, et al. (2011) Elevated microRNA miR-21 levels in pancreatic cyst fluid are predictive of mucinous precursor lesions of ductal adenocarcinoma. Pancreatology. 2011;11(3):343–50. doi: 10.1159/000329183, Epub 2011 Jul 12CrossRefGoogle Scholar
  4. Wu J et al (2011a) Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development. Sci Transl Med 3(92):92ra66. doi: 10.1126/scitranslmed. 3002543 PubMedCrossRefGoogle Scholar
  5. Wu J et al (2011b) Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways. Proc Natl Acad Sci USA 108(52):21188–21193PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • C. Max Schmidt
    • 1
    • 2
  1. 1.Department of Surgery, Biochemistry and Molecular BiologyIU Health Pancreatic Cyst and Cancer Early Detection CenterIndianapolisUSA
  2. 2.Department of Surgery, Biochemistry, and Molecular BiologyIndiana University School of MedicineIndianapolisUSA

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